Quick answer

Synthetic peptide; Composed of amino acids (alanine, proline, serine, and glycine); Works with water channels in skin’s surface layers; Helps provide balanced hydration between skin’s layers Key benefits: Anti-Aging, Hydration.

Acetyl Hexapeptide-37

Updated

Acetyl Hexapeptide-37 is the product obtained by the acetylation of Hexapeptide-37

Purpose

This synthetic peptide is composed of amino acids (alanine, proline, serine, and glycine). It works to help skin’s layers maintain adequate hydration.

Rating

BEST

Category

Peptides, Humectant

INCI Purpose

SKIN CONDITIONING

Benefits

Anti-Aging — Boosts collagen and cell turnover to reduce fine lines and wrinkles
Hydration — Attracts and locks in moisture to keep skin plump and dewy

Alternative Names

At a Glance

Synthetic peptide

Composed of amino acids (alanine, proline, serine, and glycine)

Works with water channels in skin’s surface layers

Helps provide balanced hydration between skin’s layers

Article

Acetyl hexapeptide-37 is a synthetic peptide composed of the amino acids alanine, proline, serine and glycine. This peptide works with the water channels (known as aquaporins) in skin’s surface layers, helping to provide adequate, balanced hydration between skin’s layers, a process which alleviates signs of dry, dehydrated skin.

Although there isn’t independent research confirming the effectiveness of this peptide on skin, the supplier (Lipotec) has made the results of their research available in a lengthy technical report that’s supported by third-party studies. Between this information and the wider field of published scientific research on peptides for skin, we feel confident recommending acetyl hexapeptide-37, particularly for dehydrated skin.

See: Peptides, Amino Acids

References

Lipotec, Accessed December 2021, ePublication Phytotherapy Research, December 2019, pages 3, 054–3, 063 Household and Personal Products Industry, September 2013, ePublication