Quick answer

Key benefits: Evens Skin Tone, Anti-Aging, Hydration.

Gluconolactone

PHA

Updated

D-Glucono-1,5-lactone

Purpose

This ingredient is a type of polyhydroxy acid, or PHA, which is chemically and functionally similar to an AHA.

Rating

BEST

Category

Exfoliant

INCI Purpose

CHELATING, SKIN CONDITIONING

Benefits

Evens Skin Tone — Brightens and balances complexion for a more uniform appearance
Anti-Aging — Boosts collagen and cell turnover to reduce fine lines and wrinkles
Hydration — Attracts and locks in moisture to keep skin plump and dewy

Alternative Names

Hair Profile

Helps With

Dandruff Sensitive scalp

Suitable For

All types

Role

Ultra-mild polyhydroxy acid. Gently exfoliates while acting as a humectant; no irritation.

Scalp

At a Glance

Article

Gluconolactone is a type of polyhydroxy acid, or PHA. PHAs are supposed to be as effective as AHAs, but less sensitizing.

Gluconolactone is chemically and functionally similar to AHAs (such as glycolic acid). The significant difference between it and AHAs is that gluconolactone has a larger molecular structure, which limits its ability to penetrate the skin, resulting in less potential for sensitizing side-effects. Supposedly, this reduced absorption into the skin does not hamper their effectiveness.

Does that mean gluconolactone is better for your skin than AHAs in the form of glycolic acid or lactic acid? According to an Internet-published class lecture by Dr. Mark G. Rubin, a board-certified dermatologist and assistant clinical professor of dermatology at the University of California, San Diego, research on gluconolactone demonstrated only a “6% decrease in dermal penetration” in comparison to glycolic acid, which “isn’t a dramatic improvement.”

Gluconolactone may be slightly less sensitizing for some skin types, but this isn’t the magic bullet for exfoliation some cosmetics companies have been extolling. Polyhydroxy acids can also function as antioxidants and may promote some amount of improvement in skin’s surface strength.

See: PHA, Polyhydroxy Acid, Lactobionic Acid

References