Quick answer

A synthetic peptide that supports key proteins in skin; Promotes a firmer, less lined look; Great synergy with similar signal peptides; Made using an amino acid complex and palmitic acid Key benefits: Anti-Aging.

Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine

Updated

Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is the product of the reaction of palmitic acid and diaminobutyroyl hydroxythreonine with Dipeptide-5

Purpose

A synthetic peptide that helps visibly firm skin by supporting key collagens and other proteins that play a role in maintaining skin’s natural architecture.

Rating

BEST

Category

Peptides

INCI Purpose

SKIN CONDITIONING

Benefits

Anti-Aging — Boosts collagen and cell turnover to reduce fine lines and wrinkles

Alternative Names

At a Glance

A synthetic peptide that supports key proteins in skin

Promotes a firmer, less lined look

Great synergy with similar signal peptides

Made using an amino acid complex and palmitic acid

Article

Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine is a synthetic signal peptide that helps support specific collagens and proteins found in skin’s dermal-epidermal junction. It also promotes a smoother, less lined skin texture and firmer-feeling surface.

This peptide is made by combining the palm-derived fatty acid palmitic acid with the amino acids lysine, valine, and threonine along with diaminobutyric acid, which is a complex amino acid in which some of the hydrogen molecules are replaced by amino groups. In essence, Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine is a complex ingredient!

It is used in blends combined with other peptides, in amounts between 1–3%, which puts each peptide in the range clinical data shows is necessary for visible results. In vivo research has shown the synergy of palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine with supporting peptides is what drives its impressive results.

See: Peptides, Palmitic Acid

References

Journal of Cosmetic Dermatology, April 2022, pages 3, 458–3, 463 Maibach, Howard I and Gorouhi, Farzam Textbook of Aging Skin, January 2016, pages 1–33 Journal of Cosmetic Dermatology, June 2010, pages 108–116