Quick answer

Helps strengthen skin’s underlying supportive elements; Backed by research for minimizing the appearance of wrinkles; Designated as a “messenger peptide” because of its ability to “tell” skin how to look better; Also goes by the names pal-GHK and palmitoyl oligopeptide; Safe history of use in cosmetics Key benefits: Anti-Aging.

Palmitoyl Tripeptide-1

Signal peptides

Updated

L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl-

Purpose

Synthetic peptide proven to strengthen skin’s underlying supportive elements and visibly reduce signs of sun damage such as wrinkles and rough texture.

Rating

BEST

Category

Peptides

INCI Purpose

SKIN CONDITIONING

Benefits

Anti-Aging — Boosts collagen and cell turnover to reduce fine lines and wrinkles

Alternative Names

At a Glance

Helps strengthen skin’s underlying supportive elements

Backed by research for minimizing the appearance of wrinkles

Designated as a “messenger peptide” because of its ability to “tell” skin how to look better

Also goes by the names pal-GHK and palmitoyl oligopeptide

Safe history of use in cosmetics

Article

Palmitoyl tripeptide-1 is a synthetic fatty acid-linked peptide that can help repair visible skin damage and strengthen skin’s underlying supportive elements. It’s categorized as a “messenger peptide” because of its ability to “tell” skin how to look better, specifically regarding reducing signs of sun damage like wrinkles and rough texture.

Some research has shown that this peptide has similar anti-aging benefits to retinol. (You can use both ingredients for even greater benefits.)

Palmitoyl tripeptide-1 also goes by the names pal-GHK and palmitoyl oligopeptide. It appears as a white powder in its raw material form.

In 2018, the Cosmetic Ingredient Review Expert Panel looked at personal care products using palmitoyl tripeptide-1 between 0.0000001% to 0.001% and deemed it was safe in current practice of use and concentration. As with most lab-made peptides, a little goes a long way.

See: Peptides

References

International Journal of Toxicology, November 2018, pages 90S-102S Cosmetics, May 2017, pages 1-14 Experimental and Therapeutic Medicine, August 2016, pages 1, 171-1, 176 International Journal of Cosmetic Science, June 2000, pages 207-218