Quick answer

Synthetic tripeptide that’s patented and proven to help aging skin; Visibly reduces fine lines and wrinkles (including deep wrinkles); Encourges a firmer look and feel; Helps reduce rough texture Key benefits: Anti-Aging.

Palmitoyl Tripeptide-5

Updated

Palmitoyl Tripeptide-5 is the reaction product of palmitic acid and Tripeptide-5

Purpose

Anti-aging peptide proven to visibly impact wrinkles, firmness, and rough texture for smoother, younger-looking skin.

Rating

BEST

Category

Peptides

INCI Purpose

SKIN CONDITIONING

Benefits

Anti-Aging — Boosts collagen and cell turnover to reduce fine lines and wrinkles

Alternative Names

At a Glance

Synthetic tripeptide that’s patented and proven to help aging skin

Visibly reduces fine lines and wrinkles (including deep wrinkles)

Encourges a firmer look and feel

Helps reduce rough texture

Article

Palmitoyl Tripeptide-5 is a synthetic, patented signal peptide made from the amino acids lysine and valine combined with the fatty acid palmitic acid, which aids penetration. It has a visible impact on skin’s firmness and also helps smooth the appearance of fine lines and wrinkles, including deep wrinkles.

Peer-reviewed published research has shown that this peptide helps support several components of what’s known as skin’s extracellular matrix, including collagen and hyaluronic acid, so skin looks smoother and more youthful. It can also help inhibit environmentally-generated (as in sun exposure) damaging enzymes in skin that degrade its firmness and resilience.

Use levels of palmitoyl tripeptide-5 in cosmetics range from 1–3% as a blend supplied in a water and glycerin base.

See: Peptides

References

Molecules, March 2023, pages 1–12 Pharmaceuticals, July 2021, pages 1–22 Frontiers in Chemistry, October 2020, pages 1–8 Journal of Topical and Cosmetic Science, October 2020, pages 77–82 Household and Personal Care Today, November/December 2015, pages 6–11 The Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38–43