Quick answer

Humectant that provides long-lasting hydration; Hydrating efficacy rivals (some studies show it surpasses) hyaluronic acid; Made via fermentation of glutamic acid with Bacillus subtilis.; May be animal-derived or synthetic Key benefits: Hydration, Anti-Aging.

Polyglutamic Acid

Updated

Polymer of glutamic acid

Purpose

Established humectant available in a range of molecular sizes, including those capable of penetrating skin’s surface for long-lasting moisture retention.

Rating

BEST

Category

Humectant, Polymer

INCI Purpose

SKIN CONDITIONING

Benefits

Hydration — Attracts and locks in moisture to keep skin plump and dewy
Anti-Aging — Boosts collagen and cell turnover to reduce fine lines and wrinkles

Alternative Names

At a Glance

Humectant that provides long-lasting hydration

Hydrating efficacy rivals (some studies show it surpasses) hyaluronic acid

Made via fermentation of glutamic acid with Bacillus subtilis.

May be animal-derived or synthetic

Article

Polyglutamic acid is a water-soluble humectant capable of attracting and holding water within skin and on its surface. It’s a polymer of the amino acid glutamic acid that’s made via bacterial fermentation using various types of skin-friendly Bacillus, a gram-positive, rod-shaped bacteria. The resulting ingredient has been shown to rival hydrating results of hyaluronic acid; in fact, some studies indicate it surpasses hyaluronic acid, although it does not have that ingredient’s antioxidant or skin-soothing properties, nor is polyglutamic acid naturally found in skin.

Although it’s not as well-rounded in the benefits-for-skin department as hyaluronic acid, polyglutamic acid remains a worthwhile ingredient. Just like hyaluronic acid, it’s available in various molecular weights, some capable of penetrating skin’s uppermost layers for multi-level hydration and prevention of water loss that leads to dehydration.

Another aspect of polyglutamic acid that it shares with hyaluronic acid is that it forms what’s described as a hydrogel mesh network. This network expands to attract and hold water plus aid delivery of antioxidants (such as quercetin and ferulic acid) to skin that would otherwise prove difficult.

Outside the cosmetics industry, polyglutamic acid has gained notoriety for it applications in other fields such as medicine, wastewater treatment, “bio-ink”, and foods. It has replaced or is being studied to replace various other ingredients that are not biodegradable, making polyglutamic acid an environmentally friendly option. Standard usage levels in cosmetics range from 0.05%–1%.

References

Biomass Conversion and Biorefinery, March 2021, ePublication Molecules, July 2020, pages 1–33 Journal of Materials Science, Materials in Medicine, Volume 31, May 2020, ePublication Journal of Biomedical Materials Research, November 2017, pages Saudi Journal of Biological Sciences, April 2014, pages 153–158