Quick answer

Amino acid used in the body’s synthesis of proteins; Considered a conditionally essential amino acid; Helps skin retain moisture; Supports structures that keep skin looking and feeling younger Key benefits: Hydration, Anti-Aging.

Proline

Updated

2-Pyrrolidinecarboxylic acid, (S)-

Purpose

This amino acid helps skin retain moisture and supports the structures in skin that keep it looking and feeling youthful.

Rating

BEST

Category

Humectant

INCI Purpose

HAIR CONDITIONING, SKIN CONDITIONING

Benefits

Hydration — Attracts and locks in moisture to keep skin plump and dewy
Anti-Aging — Boosts collagen and cell turnover to reduce fine lines and wrinkles

Alternative Names

At a Glance

Amino acid used in the body’s synthesis of proteins

Considered a conditionally essential amino acid

Helps skin retain moisture

Supports structures that keep skin looking and feeling younger

Article

Proline is an amino acid that is used in the body’s synthesis of proteins. While the body can produce proline, its synthesis can be limited by certain physiological circumstances, which has led some scientists to refer to proline as a conditionally essential amino acid. In those circumstances, it must be consumed as part of a person’s diet for them to obtain the proper amount.

Like all amino acids, proline helps skin retain moisture, adding to a supple look and feel. It also helps support structures that prevent the appearance of fine lines and wrinkles.

As an amino acid, it is considered safe as used in cosmetics; in fact, proline is part of many peptides used in skin care. Forms of this amino acid, such as cocoyl proline, are typically used in concentrations between 0.1–5%.

See: Cocoyl Proline, Dipalmitoyl Hydroxyproline, Palmitoyl Proline, Amino Acids

References

Amino Acids in Nutrition and Health, August 2020, pages 187-199 Current Medicinal Chemistry, December 2018, pages 5, 512-5, 527 PLoS ONE, February 2018, ePublication International Journal of Cosmetic Science, August 2009, pages 327-345