Quick answer
Vegan, collagen-identical peptide made via fermentation; Shown to reduce the look of wrinkles and boost skin’s resilience; Soothing properties visibly reduce redness and puffiness; Excellent synergy with vitamin C Key benefits: Anti-Aging, Soothing.
Sh-polypeptide-121
Updated
sh-Polypeptide-121 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Collagen alpha-1(XXI) chain used such or adapted to the production host. It contains a maximum of 957 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
Purpose
This bio-identical single chain peptide plays a role in helping to shore up skin’s underlying support, smoothing wrinkles and improving resilience, among other benefits.
Rating
BEST
Category
Peptides
INCI Purpose
FILM FORMING, SKIN CONDITIONING
Benefits
Alternative Names
At a Glance
Vegan, collagen-identical peptide made via fermentation
Shown to reduce the look of wrinkles and boost skin’s resilience
Soothing properties visibly reduce redness and puffiness
Excellent synergy with vitamin C
Article
Sh-Polypeptide-121 is bio-identical vegan collagen signal peptide produced via bacterial fermentation. Research from the supplier has shown this single chain peptide can increase skin’s tensile strength by helping to bolster its supportive elements. This also helps smooth the appearance of wrinkles.
Sh-polypeptide-121 has excellent synergy with vitamin C, with supplier studies showing the combination leads to a significant improvement in skin’s firm look and feel. It also has soothing properties that may play a role in reducing the appearance of puffy eyes and reddened skin.
This peptide is supplied as a solution or a powder. Usage levels vary by format, with the recommended level for the solution being 2% and the more concentrated powder being at 0.1%.
References