Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Synthetic peptide helps improve skin’s hyaluronic acid content

Helps maintain surface hydration and smoothness

Contributes to a firmer look and feel

Not shown to improve wrinkle depth better than placebo

Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate (say that five times fast!) is a synthetic tripeptide said to help improve skin’s hyaluronic acid content. This improves its ability to maintain surface hydration and helps to visibly restore a firmer appearance.

Clinical studies from this ingredient’s supplier show that it helps improve the “biomechanical properties” of skin.

This means ongoing use helps to improve skin’s ability to bounce back when stretched, something which naturally declines with age and is compounded by cumulative environmental damage. It was also shown to smooth rough texture and decrease wrinkle volume, although the latter benefit was also achieved with a placebo product. These studies were done on human skin and objectively measured over a period of 8 weeks.

In vitro data indicate that this peptide helps support skin’s underlying elements, further contributing to the look and feel of firmer, smoother skin.

This peptide is supplied as a liquid, with the peptide combined with magnesium chloride and glycerin or similar substances to enhance skin compatibility and improve penetration. The recommended usage levels of tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate in such blends is 2–3%.

See: Urea, Peptides