Products

The Ordinary

Argireline Solution 10%

face serum

The Ordinary

Argireline Solution 10%

face serum

Added June 7, 2026 Last edited June 7, 2026

Fit by skin type

General, ingredient-based — not your personalized match.

Dry

54%

Combination (dry)

54%

Balanced

84%

Combination (oily)

86%

Oily

86%

See how this fits your skin

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Ingredients

Benefits

Actives

Find Dupes

A non-injective solution for visible, dynamic lines.

Key Insights

Benefits

Anti-Aging

Hydration

Active Ingredients

Neuropeptides

Full Ingredients

11 total

WATER PROPANEDIOL ACETYL HEXAPEPTIDE-8 Neuropeptides TRISODIUM ETHYLENEDIAMINE DISUCCINATE GELLAN GUM SODIUM CHLORIDE ISOCETETH-20 DIMETHYL ISOSORBIDE POTASSIUM SORBATE PHENOXYETHANOL CHLORPHENESIN

About Argireline Solution 10%

Overview

Argireline Solution 10% is a lightweight serum from The Ordinary, a brand based in Canada. The formula is built mainly around hydration. The ingredient list runs to 11 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Hydration is handled by Propanediol, Water and Acetyl Hexapeptide-8, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Propanediol, Water and Acetyl Hexapeptide-8.

Firmness signalling: Moderate. Peptides and growth factors that signal for collagen support, and here that comes from Acetyl Hexapeptide-8.

Who it suits

On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on barrier support, antioxidant protection, oil control and brightening and tone. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, silicone-free and microplastic-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

No fragrance or declared allergens
No essential oils
No drying alcohol
Silicone-free
No microplastics
Strong humectant content for hydration
No common irritants flagged in the list
No recognised malassezia (fungal acne) triggers

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

Balanced skin
Combination (oily) skin
Oily skin

Less suitable for

Dry skin
Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

Hydration 3 ingredients

Attracts and locks in moisture to keep skin plump and dewy
Anti-Aging 1 ingredient

Boosts collagen and cell turnover to reduce fine lines and wrinkles

Does not target

Anti-Acne Blackhead Reducing Dark Spot Fading Evens Skin Tone Oil Control Pore Minimizer Smooths Bumpy Skin Soothing

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

Water

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

Propanediol

2nd on the list, which puts it at an estimated 5–20% of the formula.

1,3-dihydroxypropane

Hydration

Acetyl Hexapeptide-8 Neuropeptides

3rd on the list, which puts it at an estimated 5–20% of the formula.

Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues

Anti-Aging Hydration

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration High

Ingredients that pull and hold water in the upper layers of skin

Barrier support None

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control None

Ingredients that moderate sebum or absorb shine

Brightening None

Ingredients that act on uneven tone and post-inflammatory marks

Soothing None

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling Moderate

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (1)

Acetyl Hexapeptide-8 · 5–20%

Supporting ingredients (10)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Propanediol Trisodium Ethylenediamine Disuccinate Gellan Gum Sodium Chloride Isoceteth-20 Dimethyl Isosorbide Potassium Sorbate Phenoxyethanol Chlorphenesin

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

Fragrance-free
Essential-oil-free
No drying alcohol
Paraben-free
Silicone-free
Microplastic-free
Sulfate-free
Dye-free
Oil-free
No animal-derived ingredients

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

Vitamin C (L-ascorbic acid)
Retinoids (retinol, retinal)
AHAs (glycolic, lactic)
BHA (salicylic acid)
PHAs (gluconolactone)
Benzoyl peroxide
Azelaic acid
Copper peptides
Bakuchiol
Niacinamide
Hyaluronic acid
Ceramides
Signal peptides
Panthenol
Sunscreen

Nothing in this formula belongs to a group our rules can put in conflict, so it layers freely. Order still matters — thinnest texture first.

Where it fits in a routine

Cleanse
Toning
Treat
Moisturise
Protect

This product is the "Treat" step.

Apply to clean, dry skin and give it a minute to absorb before the next layer.
Introduce one new treatment at a time so you can identify what is working.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding: Nothing in this formula is on the standard pregnancy-caution list. That is not clearance — ask your doctor about anything you use daily.
Fungal acne (malassezia): No ingredient here is a recognised food source for malassezia.
Sensitive and reactive skin: No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 11 ingredients on the label.

Texture agent

Sets the thickness, spread and stability of the formula

Preservative

Keeps the product free of microbial growth

Solvent

Dissolves and carries everything else

Active

Changes how skin behaves rather than how it feels

Humectant

Draws water into the upper layers of skin

Chelator

Binds trace metals that would otherwise spoil the formula

Occlusive

Forms a film that slows water loss

Peptide

Amino-acid chains that signal for repair or firmness

Surfactant

Lifts oil and dirt, or holds oil and water together

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent

Estimated level: 30–80%
Confidence: Moderate — INCI order above the 1% line
Roles: Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

3 scientific references

Skin Research and Technology, May 2015, pages 131-136
Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
Journal of Cosmetic Science, September-October 1993, pages 249-262

2 Propanediol Texture agent

Estimated level: 5–20%
Confidence: Moderate — INCI order above the 1% line
Roles: Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

1,3-dihydroxypropane

Hydration

4 scientific references

PubChem Compound Summary, April 2021, ePublication
SpecialChem, Accessed April 2021, ePublication
Cosmetic Ingredient Review, June 2018, pages 1-73
Cosmetics & Toiletries, May 2013, pages 81-86

3 Acetyl Hexapeptide-8 Humectant

Estimated level: 5–20%
Confidence: Moderate — INCI order above the 1% line
Roles: Humectant, Active, Peptide

3rd on the list, which puts it at an estimated 5–20% of the formula.

Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues

Anti-Aging Hydration

6 scientific references

Cosmetics, November 2020, Issue 7, Volume 4, page 91
La Clinica Terapeutica, November 2020, pages e539-e548
https://wwwcir-safetyorg/sites/default/files/AcetylHexapeptide-8pdf
Cutaneous and Ocular Toxicology, March 2015, pages 46-52
European Journal of Pharmaceutical Sciences, February 2015, pages 27-35
Dermatologic Therapy, September-October 2007, issue 5, pages 343-349

4 Trisodium Ethylenediamine Disuccinate Chelator

Estimated level: 2–10%
Confidence: Moderate — INCI order above the 1% line
Roles: Chelator

4th on the list, which puts it at an estimated 2–10% of the formula.

L-Aspartic acid, N,N'-1,2-ethanediylbis-, trisodium salt

5 Gellan Gum Occlusive

Estimated level: 2–10%
Confidence: Moderate — INCI order above the 1% line
Roles: Occlusive, Texture agent

5th on the list, which puts it at an estimated 2–10% of the formula.

Gellan gum

6 Sodium Chloride Texture agent

Estimated level: 2–10%
Confidence: Moderate — INCI order above the 1% line
Roles: Texture agent

6th on the list, which puts it at an estimated 2–10% of the formula.

Sodium chloride

7 Isoceteth-20 Surfactant

Estimated level: 1–5%
Confidence: Moderate — INCI order above the 1% line
Roles: Surfactant

7th on the list, which puts it at an estimated 1–5% of the formula.

Alcohols, C16-branched, ethoxylated (20 mol EO average molar ratio)

8 Dimethyl Isosorbide Texture agent

Estimated level: 1–5%
Confidence: Moderate — INCI order above the 1% line
Roles: Texture agent, Solvent

8th on the list, which puts it at an estimated 1–5% of the formula.

1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol

9 Potassium Sorbate Preservative

Estimated level: under 1%
Confidence: Moderate — listed below the 1% line
Roles: Preservative

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Potassium (E,E)-hexa-2,4-dienoate

10 Phenoxyethanol Preservative

Estimated level: under 1%
Confidence: Moderate — listed below the 1% line
Roles: Preservative

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Phenoxyethanol

11 Chlorphenesin Preservative

Estimated level: under 1%
Confidence: Moderate — listed below the 1% line
Roles: Preservative

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(4-chlorophenoxy)-