NEOGEN
Dermalogy Real Peptide Serum
face serum
NEOGEN
face serum
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Fit by skin type
General, ingredient-based — not your personalized match.
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| PANTHENOL | 5% |
A revolutionary serum that combines 13 potent peptides to provide vitality and rejuvenation to the skin. This symphony of peptides not only nourishes the skin but also infuses it with renewed vitality, transforming it from dry and lackluster to radiant. The addition of adenosine ingredients enhances overall elasticity.
Dermalogy Real Peptide Serum is a lightweight serum from NEOGEN. The formula is built mainly around firmness signalling and hydration. The ingredient list runs to 53 ingredients, each broken down in full below.
By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Hydration is handled by Panthenol, Butylene Glycol and Propanediol, humectants that pull water into the upper layers of skin rather than sealing it there.
Firmness signalling: Very high. Peptides and growth factors that signal for collagen support, and here that comes from Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1 and Tripeptide-29.
Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Panthenol, Butylene Glycol, Propanediol and Sodium Hyaluronate.
Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Tripeptide-29, Panthenol, Hydrogenated Lecithin and Niacinamide.
On richness alone it suits Balanced skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.
The formula contributes little or nothing on oil control and cell renewal. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.
Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, silicone-free and microplastic-free. Those claims come from the ingredient list itself, not from the packaging.
It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.
This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.
Drawn purely from the ingredient list
Scored on how rich or light the formula reads from its INCI order.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Based on the curated benefits documented for this product's ingredients.
Boosts collagen and cell turnover to reduce fine lines and wrinkles
Attracts and locks in moisture to keep skin plump and dewy
Calms redness, irritation, and inflammation for sensitive skin
Brightens and balances complexion for a more uniform appearance
Fades hyperpigmentation and evens out dark spots over time
Tightens and refines the look of enlarged pores
None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.
The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.
1st on the list, which puts it at an estimated 10–40% of the formula.
Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues
2nd on the list, which puts it at an estimated 5–20% of the formula.
Copper Tripeptide-1 is a copper complex of Tripeptide-1
3rd on the list, which puts it at an estimated 5–20% of the formula.
Tripeptide-1 is a synthetic peptide containing glycine, histidine, and lysine
4th on the list, which puts it at an estimated 2–10% of the formula.
Tripeptide-29 is the synthetic peptide consisting of glycine, proline and hydroxyproline
5th on the list, which puts it at an estimated 2–10% of the formula.
Palmitoyl Tetrapeptide-7 is the reaction product of palmitic acid and Tetrapeptide-7
6th on the list, which puts it at an estimated 2–10% of the formula.
L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl-
7th on the list, which puts it at an estimated 1–5% of the formula.
Lysine, synthetic pentapeptide with serine, and threonine, hexadecanoyl derivatives
12th on the list, which puts it at an estimated 1–3% of the formula.
Hexapeptide-11 is a synthetic peptide containing Alanine, Phenylalanine, Proline and Valine residues
13th on the list, which puts it at an estimated 1–3% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
14th on the list, which puts it at an estimated 1–3% of the formula.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
15th on the list, which puts it at an estimated 1–3% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
16th on the list, which puts it at an estimated 1–3% of the formula.
1,3-dihydroxypropane
Each axis is scored from the ingredients present and how high up the list they sit.
Ingredients that pull and hold water in the upper layers of skin
Lipids and repair signals that support skin barrier integrity
Ingredients that mop up free radicals from UV and pollution
Ingredients that moderate sebum or absorb shine
Ingredients that act on uneven tone and post-inflammatory marks
Ingredients aimed at visible redness and reactivity
Retinoids, acids and enzymes that speed surface turnover
Peptides and growth factors that signal for collagen support
"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.
Solvents, emollients, texture agents and preservatives — the formula that carries the actives.
Read from the full ingredient list. A brand's own claim may differ.
Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
This product is the "Treat" step.
Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.
Most ingredients do more than one job, so these counts add up to more than the 53 ingredients on the label.
Changes how skin behaves rather than how it feels
Amino-acid chains that signal for repair or firmness
Draws water into the upper layers of skin
Botanical material, usually for antioxidants or scent
Sets the thickness, spread and stability of the formula
Dissolves and carries everything else
Forms a film that slows water loss
Lifts oil and dirt, or holds oil and water together
Neutralises free radicals from UV and pollution
Softens and smooths by filling gaps between skin cells
Sets the acidity the formula needs to work
Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.
1st on the list, which puts it at an estimated 10–40% of the formula.
Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues
2nd on the list, which puts it at an estimated 5–20% of the formula.
Copper Tripeptide-1 is a copper complex of Tripeptide-1
3rd on the list, which puts it at an estimated 5–20% of the formula.
Tripeptide-1 is a synthetic peptide containing glycine, histidine, and lysine
4th on the list, which puts it at an estimated 2–10% of the formula.
Tripeptide-29 is the synthetic peptide consisting of glycine, proline and hydroxyproline
5th on the list, which puts it at an estimated 2–10% of the formula.
Palmitoyl Tetrapeptide-7 is the reaction product of palmitic acid and Tetrapeptide-7
6th on the list, which puts it at an estimated 2–10% of the formula.
L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl-
7th on the list, which puts it at an estimated 1–5% of the formula.
Lysine, synthetic pentapeptide with serine, and threonine, hexadecanoyl derivatives
8th on the list, which puts it at an estimated 1–5% of the formula.
Hexapeptide-12 is a synthetic peptide containing Alanine, Glycine, Proline and Valine residues
9th on the list, which puts it at an estimated 1–5% of the formula.
Hexapeptide-9 is a synthetic peptide containing Glutamine, Glycine and Proline residues
10th on the list, which puts it at an estimated 1–5% of the formula.
Tripeptide-2 is a synthetic peptide containing tryrosine and valine residues
11th on the list, which puts it at an estimated 1–3% of the formula.
Nonapeptide-1 is a synthetic nonapeptide derived from arginine, lysine, methionine, phenylalanine, proline, tryptophan and valine
12th on the list, which puts it at an estimated 1–3% of the formula.
Hexapeptide-11 is a synthetic peptide containing Alanine, Phenylalanine, Proline and Valine residues
13th on the list, which puts it at an estimated 1–3% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
14th on the list, which puts it at an estimated 1–3% of the formula.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
15th on the list, which puts it at an estimated 1–3% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
16th on the list, which puts it at an estimated 1–3% of the formula.
1,3-dihydroxypropane
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio)
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Melia Azadirachta Leaf Extract is an extract of the leaves of the Neem Tree, Melia azadirachta L., Meliaceae
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Melia Azadirachta Flower Extract is an extract of the flowers of the Neem Tree, Melia Azadirachta L., Meliaceae
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Coccinia Indica Fruit Extract is an extract of the fruit of Coccinia indica, Cucurbitaceae
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Solanum Melogena Fruit Extract is an extract of the fruit of the Eggplant, Solanum melongena L., Solanaceae
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ocimum Sanctum Leaf Extract is an extract of the leaves of Ocimum sanctum, Labiatae
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Xanthan gum
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Curcuma Longa Root Extract is an extract of the rhizomes of the Turmeric, Curcuma longa L., Zingiberaceae
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Corallina Officinalis Extract is an extract of the Alga, Corallina officinalis L., Corallinaceae
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octane-1,2-diol
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lecithins, hydrogenated
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
L-Ascorbic acid, 2-(dihydrogen phosphate), trisodium salt
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glucose
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Chondrus Crispus Extract is an extract of the carrageenan, Chondrus crispus, Gigartinaceae
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, 2-hydroxy-3-(N,N,N-trimethylammonio)propyl chloride derivatives
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, [3aS-(3a.alpha.,4.beta.,6a.alpha.)]-
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-; vitamine B6
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Folic acid
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis
43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sodium Acetylhyaluronate
44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cyanocobalamin; Vitamine B12
45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid
47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium salt, polymer with 1,1'-sulfonylbis[ethene]
48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Sodium Hyaluronate is the hydrolysate of Sodium Hyaluronate derived by acid, enzyme or other method of hydrolysis
49th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Riboflavin
50th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
51st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
9,12-Octadecadienoic acid (9Z, 12Z)-
52nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, potassium salt
53rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
.beta.,.beta.-carotene
Products in the same category that share this formula's distinguishing ingredients.
Arencia
Shares 18 key ingredients with Dermalogy Real Peptide Serum: Water, Propanediol, Sodium Hyaluronate, Niacinamide, Potassium Hyaluronate
Arencia
Shares 18 key ingredients with Dermalogy Real Peptide Serum: Water, Butylene Glycol, Propanediol, Niacinamide, Sodium Hyaluronate
Eqqualberry
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Numbuzin
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VT Cosmetics
Shares 14 key ingredients with Dermalogy Real Peptide Serum: Water, Niacinamide, Propanediol, Butylene Glycol, Sodium Hyaluronate
ACETYL HEXAPEPTIDE-8, COPPER TRIPEPTIDE-1, TRIPEPTIDE-1, TRIPEPTIDE-29, PALMITOYL TETRAPEPTIDE-7, PALMITOYL TRIPEPTIDE-1, PALMITOYL PENTAPEPTIDE-4, HEXAPEPTIDE-12, HEXAPEPTIDE-9, TRIPEPTIDE-2, NONAPEPTIDE-1, HEXAPEPTIDE-11, WATER, PANTHENOL, BUTYLENE GLYCOL, PROPANEDIOL, 1,2-HEXANEDIOL, POLYGLYCERYL-10 LAURATE, SODIUM HYALURONATE, CARBOMER, ETHYLHEXYLGLYCERIN, TROMETHAMINE, MELIA AZADIRACHTA LEAF EXTRACT, MELIA AZADIRACHTA FLOWER EXTRACT, COCCINIA INDICA FRUIT EXTRACT, SOLANUM MELONGENA FRUIT EXTRACT, GLYCERIN, OCIMUM SANCTUM LEAF EXTRACT, XANTHAN GUM, CURCUMA LONGA ROOT EXTRACT, CORALLINA OFFICINALIS EXTRACT, CAPRYLYL GLYCOL, HYDROGENATED LECITHIN, SODIUM ASCORBYL PHOSPHATE, GLUCOSE, NIACINAMIDE, CHONDRUS CRISPUS EXTRACT, HYDROXYPROPYLTRIMONIUM HYALURONATE, BIOTIN, PYRIDOXINE, FOLIC ACID, HYDROLYZED HYALURONIC ACID, SODIUM ACETYLATED HYALURONATE, CYANOCOBALAMIN, TOCOPHEROL, HYALURONIC ACID, SODIUM HYALURONATE CROSSPOLYMER, HYDROLYZED SODIUM HYALURONATE, RIBOFLAVIN, THIAMINE HCL, LINOLEIC ACID, POTASSIUM HYALURONATE, BETA-CAROTENE.
ACETYL HEXAPEPTIDE-8, COPPER TRIPEPTIDE-1, TRIPEPTIDE-1, TRIPEPTIDE-29, PALMITOYL TETRAPEPTIDE-7, PALMITOYL TRIPEPTIDE-1, PALMITOYL PENTAPEPTIDE-4, HEXAPEPTIDE-11, PANTHENOL, SODIUM HYALURONATE, SODIUM ASCORBYL PHOSPHATE, NIACINAMIDE, HYDROLYZED HYALURONIC ACID, SODIUM ACETYLATED HYALURONATE, HYALURONIC ACID, SODIUM HYALURONATE CROSSPOLYMER, POTASSIUM HYALURONATE.
Before applying face cream in the morning and evening, spread the serum evenly onto your face and tap gently to ensure absorption.
Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry) skin.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
One ingredient could feed malassezia: Polyglyceryl-10 Laurate. That describes the yeast's food supply, not a prediction that it will cause a breakout.
Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.
Yes. Reading the full ingredient list, this formula is fragrance-free.
No. Reading the full ingredient list, this formula is no drying alcohol.
Yes. Reading the full ingredient list, this formula is silicone-free.
No. Reading the full ingredient list, this formula is essential-oil-free.
Yes. Reading the full ingredient list, this formula is paraben-free.
It layers well with Vitamin C (L-ascorbic acid), Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Azelaic acid. Take more care combining it with Benzoyl peroxide — use them in separate routines or on alternate days.
Use it morning and evening, after toner, before moisturiser.
It lists 53 ingredients, of which 17 are recorded as actives.
NEOGEN.
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