1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
La Roche-Posay
Retinol B3 Anti-wrinkle Anti-Ageing Serum
face serum
La Roche-Posay
face serum
Added Last edited
Fit by skin type
General, ingredient-based — not your personalized match.
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Take the skin testA retinol and vitamin B3 serum to reduce the look of fine lines and promote a visibly radiant and refined complexion. Specially formulated with sensitive skin in mind, this lightweight yet concentrated serum supports a smoother, more even-looking appearance.
Retinol B3 Anti-wrinkle Anti-Ageing Serum is a lightweight serum from La Roche-Posay, a brand based in France. The formula is built mainly around hydration. The ingredient list runs to 22 ingredients, each broken down in full below.
By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Glycerin, Sodium Hyaluronate and Water, humectants that pull water into the upper layers of skin rather than sealing it there.
Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Sodium Hyaluronate, Water and Cyclohexasiloxane.
Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Niacinamide, Sodium Hyaluronate, Adenosine and Tocopherol.
On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.
The formula contributes little or nothing on antioxidant protection and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.
Reading the full list, the formula is essential-oil-free, paraben-free, microplastic-free, sulfate-free, dye-free and oil-free. Those claims come from the ingredient list itself, not from the packaging. It does contain fragrance and drying alcohol, worth knowing if your skin reacts to any of them.
It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.
This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.
Drawn purely from the ingredient list
Scored on how rich or light the formula reads from its INCI order.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Based on the curated benefits documented for this product's ingredients.
Boosts collagen and cell turnover to reduce fine lines and wrinkles
Attracts and locks in moisture to keep skin plump and dewy
Calms redness, irritation, and inflammation for sensitive skin
Tightens and refines the look of enlarged pores
Targets breakouts by reducing bacteria and unclogging pores
Brightens and balances complexion for a more uniform appearance
None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.
The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
3rd on the list, which puts it at an estimated 5–20% of the formula.
Dodecamethylcyclohexasiloxane
5th on the list, which puts it at an estimated 2–10% of the formula.
1,2-Dihydroxypentane
6th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
7th on the list, which puts it at an estimated 1–5% of the formula.
Dimethicone
10th on the list, which puts it at an estimated 1–5% of the formula.
Hyaluronic acid, sodium, salt
11th on the list, which puts it at an estimated 1–3% of the formula.
Retinol; vitamin A
12th on the list, which puts it at an estimated 1–3% of the formula.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
15th on the list, which puts it at an estimated 1–3% of the formula.
2-Hydroxy-1,2,3-propanetricarboxylic acid
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Retinol, hexadecanoate
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
Each axis is scored from the ingredients present and how high up the list they sit.
Ingredients that pull and hold water in the upper layers of skin
Lipids and repair signals that support skin barrier integrity
Ingredients that mop up free radicals from UV and pollution
Ingredients that moderate sebum or absorb shine
Ingredients that act on uneven tone and post-inflammatory marks
Ingredients aimed at visible redness and reactivity
Retinoids, acids and enzymes that speed surface turnover
Peptides and growth factors that signal for collagen support
"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.
Solvents, emollients, texture agents and preservatives — the formula that carries the actives.
Read from the full ingredient list. A brand's own claim may differ.
Parfum
Alcohol Denat.
Cyclohexasiloxane, Dimethicone, Polysilicone-11
Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
This product is the "Treat" step.
Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.
Most ingredients do more than one job, so these counts add up to more than the 22 ingredients on the label.
Changes how skin behaves rather than how it feels
Dissolves and carries everything else
Softens and smooths by filling gaps between skin cells
Sets the thickness, spread and stability of the formula
Forms a film that slows water loss
Draws water into the upper layers of skin
Binds trace metals that would otherwise spoil the formula
Keeps the product free of microbial growth
Lifts oil and dirt, or holds oil and water together
Changes how the product smells or looks
Neutralises free radicals from UV and pollution
Sets the acidity the formula needs to work
Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
3rd on the list, which puts it at an estimated 5–20% of the formula.
Dodecamethylcyclohexasiloxane
4th on the list, which puts it at an estimated 2–10% of the formula.
Alcohol Denat. is ethyl alcohol that is denatured with one or more denaturing agents in accordance with the national legislation of each European Community (EU) country.
5th on the list, which puts it at an estimated 2–10% of the formula.
1,2-Dihydroxypentane
6th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
7th on the list, which puts it at an estimated 1–5% of the formula.
Dimethicone
8th on the list, which puts it at an estimated 1–5% of the formula.
Glycine Soja Oil Unsaponifiables is the fraction of the oil obtained from the soybean, Glycine soja, Leguminosae, which has not been transformed into soap during the process of saponification
9th on the list, which puts it at an estimated 1–5% of the formula.
Tetradecanol, 2-decyl-, ethoxylated, propoxylated (30 mol EO, 6 mol PO average molar ratio)
10th on the list, which puts it at an estimated 1–5% of the formula.
Hyaluronic acid, sodium, salt
11th on the list, which puts it at an estimated 1–3% of the formula.
Retinol; vitamin A
12th on the list, which puts it at an estimated 1–3% of the formula.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
13th on the list, which puts it at an estimated 1–3% of the formula.
1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-propenyl)amino]-, monoammonium salt, homopolymer
14th on the list, which puts it at an estimated 1–3% of the formula.
Octane-1,2-diol
15th on the list, which puts it at an estimated 1–3% of the formula.
2-Hydroxy-1,2,3-propanetricarboxylic acid
16th on the list, which puts it at an estimated 1–3% of the formula.
L-Aspartic acid, N,N'-1,2-ethanediylbis-, trisodium salt
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Xanthan gum
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cyclosiloxanes, dimethyl, polymers with dimethyl, methyl hydrogen siloxanes and vinyl-group terminated dimethylsiloxanes
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Retinol, hexadecanoate
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Phenoxyethanol
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Parfum is a term for ingredient labelling used to identify that a product contains a material or a combination of materials normally added to a cosmetic to produce or to mask a particular odour. According to Article 19 of the Cosmetics Regulation, 'Perfume and aromatic compositions and their raw materials shall be referred to by the terms ‘parfum’ or ‘aroma’. '
Products in the same category that share this formula's distinguishing ingredients.
Medicube
Shares 9 key ingredients with Retinol B3 Anti-wrinkle Anti-Ageing Serum: Water, Glycerin, Niacinamide, Pentylene Glycol, Adenosine
La Roche-Posay
Shares 9 key ingredients with Retinol B3 Anti-wrinkle Anti-Ageing Serum: Water, Dimethicone, Niacinamide, Glycerin, Sodium Hyaluronate
La Roche-Posay
Shares 8 key ingredients with Retinol B3 Anti-wrinkle Anti-Ageing Serum: Water, Dimethicone, Glycerin, Sodium Hyaluronate, Adenosine
Medicube
Shares 8 key ingredients with Retinol B3 Anti-wrinkle Anti-Ageing Serum: Water, Glycerin, Niacinamide, Citric Acid, Dimethicone
innisfree
Shares 8 key ingredients with Retinol B3 Anti-wrinkle Anti-Ageing Serum: Water, Glycerin, Niacinamide, Dimethicone, Adenosine
Bioderma
Shares 8 key ingredients with Retinol B3 Anti-wrinkle Anti-Ageing Serum: Water, Glycerin, Pentylene Glycol, Niacinamide, Citric Acid
WATER, GLYCERIN, CYCLOHEXASILOXANE, ALCOHOL DENAT., PENTYLENE GLYCOL, NIACINAMIDE, DIMETHICONE, GLYCINE SOJA OIL UNSAPONIFIABLES, PPG-6-DECYLTETRADECETH-30, SODIUM HYALURONATE, RETINOL, ADENOSINE, AMMONIUM POLYACRYLOYLDIMETHYL TAURATE, CAPRYLYL GLYCOL, CITRIC ACID, TRISODIUM ETHYLENEDIAMINE DISUCCINATE, XANTHAN GUM, POLYSILICONE-11, RETINYL PALMITATE, TOCOPHEROL, PHENOXYETHANOL, PARFUM.
NIACINAMIDE, SODIUM HYALURONATE, RETINOL, CITRIC ACID, RETINYL PALMITATE.
Fill dropper with serum and apply in the evening on face and neck. Apply after cleansing. Always use in conjunction with a moisturiser. Always wear in conjunction with sunscreen when going out during the day.
Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
One ingredient could feed malassezia: Retinyl Palmitate. That describes the yeast's food supply, not a prediction that it will cause a breakout.
It contains Retinol, Retinyl Palmitate, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.
No — it contains Parfum.
Yes — it contains Alcohol Denat..
No — it contains Cyclohexasiloxane, Dimethicone, Polysilicone-11.
No. Reading the full ingredient list, this formula is essential-oil-free.
Yes. Reading the full ingredient list, this formula is paraben-free.
It layers well with Retinoids (retinol, retinal), Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides. Take more care combining it with AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide, Vitamin C (L-ascorbic acid), Azelaic acid — use them in separate routines or on alternate days.
Use it morning and evening, after toner, before moisturiser.
It lists 22 ingredients, of which 5 are recorded as actives.
La Roche-Posay, a brand based in France.
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