-
Estimated level
- 30–80%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Hydration
3 scientific references
- Skin Research and Technology, May 2015, pages 131-136
- Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
- Journal of Cosmetic Science, September-October 1993, pages 249-262
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Texture agent, Solvent
2nd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7)
(R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Hydration
5 scientific references
- CosmeticsInfoorg, Accessed March 2021, ePublication
- US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
- International Journal of Toxicology, May 2011, pages 5S-16S
- Skin Research and Technology, November 2007, pages 417-24
- Journal of the American College of Toxicology, September 1985, pages 223-248
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Occlusive, Texture agent, Solvent
3rd on the list, which puts it at an estimated 5–20% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
Hydration
Anti-Aging
6 scientific references
- Journal of Pharmaceutical Investigation, March 2021, pages 223-231
- International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
- International Journal of Cosmetic Science, August 2016, ePublication
- British Journal of Dermatology, July 2008, pages 23-34
- Journal of Cosmetic Dermatology, June 2007, pages 75-82
- Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Texture agent, Solvent
4th on the list, which puts it at an estimated 2–10% of the formula.
1,3-dihydroxypropane
Hydration
4 scientific references
- PubChem Compound Summary, April 2021, ePublication
- SpecialChem, Accessed April 2021, ePublication
- Cosmetic Ingredient Review, June 2018, pages 1-73
- Cosmetics & Toiletries, May 2013, pages 81-86
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Active
5th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
Soothing
Anti-Aging
Pore Minimizer
15 scientific references
- International Journal of Dermatology, February 2021, pages 166-173
- Biomolecules & Therapeutics, July 2019, pages 562-569
- Experimental Dermatology, February 2019, pages 15-22
- Dermatologic Therapy, September 2017, ePublication
- Journal of Investigative Dermatology, May 2017, page S116
- International Journal of Pharmaceutics, March 2017, pages 158-162
- Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
- Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
- Skin Pharmacology and Physiology, June 2014, pages 311-315
- International Journal of Pharmacy, January 2013, pages 192-201
- Dermatoendrocrinology, July 2012, pages 308-319
- International Journal of Toxicology, September 2005, pages 1-31
- Dermatologic Surgery, July 2005, pages 860-865
- International Journal of Cosmetic Science, October 2004, pages 231-238
- Journal of Cosmetic Dermatology, April 2004, pages 88-93
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Emollient, Occlusive
6th on the list, which puts it at an estimated 2–10% of the formula.
Dimethicone
Hydration
Silicone
7 scientific references
- FDA Code of Federal Regulations, April 2020, ePublication
- International Journal of Toxicology, May 2014, pages 65S-115S
- The Journal of Clinical and Aesthetic Dermatology, May 2014, pages 36-44
- Dermatologic Therapy, May 2012, pages 229-233
- Clinics in Dermatology, May-June 2012, pages 345-348
- International Journal of Cosmetic Science, January 2008, pages 19-33
- Skin Research and Technology, May 2000, pages 77-80
-
Estimated level
- 1–5%
-
Confidence
- Moderate — INCI order above the 1% line
7th on the list, which puts it at an estimated 1–5% of the formula.
1,1,5,5,5-Hexamethyl-3-phenyl-3-[(trimethylsilyl)oxy]trisiloxane
Hydration
Silicone
5 scientific references
- International Journal of Toxicology, 2006, pages 1-89
- https://onlinepersonalcarecouncilorg/ctfa-static/online/lists/cir-pdfs/PRNS513pdf
- Journal of Cosmetic Science, June 2003, pages 335-351
- Silicone Surfactants, 1999, page 190
- International Journal of Toxicology, 1986, pages 353-371
-
Estimated level
- 1–5%
-
Confidence
- Moderate — INCI order above the 1% line
8th on the list, which puts it at an estimated 1–5% of the formula.
1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Solvent
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2,6,10,15,19,23-Hexamethyltetracosane
Hydration
Anti-Aging
9 scientific references
- Cosmetics Ingredient Review, 2019, ePublication
- ACS Open, July 2017, pages 3, 989–3, 996
- Indian Journal of Dermatology, May-June 2016, pages 279-297
- The Journal of Clinical and Aesthetic Dermatology, June 2014, pages 25-32
- Journal of Cosmetic Science, January-February 2013, pages 59-66
- Advances in Food and Nutrition Research, 2012, pages 223-233
- Molecules, January 2009, pages 540-554
- Journal of Investigative Dermatology, November 2006, pages 2, 430-2, 437
- Free Radical Research, April 2002, pages 471-477
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Polysilicone-33 is a polysilsesquioxane that also contains dimethyl siloxane groups. It is produced by the hydrolysis and condensation of dimethyldimethoxysilane, Methyltrimethoxysilane, propyltrimethoxysilane, Aminopropyl Triethoxysilane, octyltriethoxysilane, and phenyltrimethoxysilane
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether
Synthetic polymer
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3-(4-Carboxy-2-oxo-1-pyrrolidinyl)propyl methyl siloxane, polymer with dimethylsiloxane, trimethylsilyl-terminated
Hydration
Silicone
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Polyacrylate Crosspolymer-6 is a copolymer of ammonium acryloyldimethyltaurate, dimethylacrylamide, lauryl methacrylate and laureth-4 methacrylate, crosslinked with trimethylolpropane triacrylate
Synthetic polymer
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
pH adjuster
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Boron nitride
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2,2-Dimethyl-2-(2'-propenamido)ethanesulfonic acid, sodium salt, homopolymer
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
UV filter, Texture agent
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Titanium dioxide (CI 77891)
Anti-Aging
10 scientific references
- Journal of Cosmetic Dermatology, February 2021, pages 532-537
- Frontiers in Bioengineering and Biotechnology, June 2020
- Journal of Nanoparticle Research, March 2020
- Journal of the European Academy of Dermatology and Venereology, November 2019, pages 34-46
- Photodermatology, Photoimmunology and Photomedicine, November 2019, pages 442-446
- Journal of Cosmetic Science, September 2019, pages 223-234
- Materials, July 2019, pages 1-24
- Photodermatology, Photoimmunology, and Photomedicine, April 2011, pages 58-67
- Skin Therapy Letter, July-August 2008, pages 5-7
- Environmental and Health Perspectives, July 2008, pages 893
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Emollient
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Poly[oxy(dimethylsilylane)], .alpha.-hydro-.omega.-hydroxy-
Hydration
3 scientific references
- CosmeticsInfoorg, Accessed September 2021, ePublication
- International Journal of Toxicology, November 2017, pages 31S-50S
- International Journal of Cosmetic Science, April 2005, page 139
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Fluorphlogopite, Mg3K[AlF2O(SiO3)3] (synthetic)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient, Surfactant
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octanoic acid, monoester with glycerol
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Chelator, pH adjuster
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sodium metaphosphate
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
Hydration
5 scientific references
- PLoS One, October 2016, ePublication
- Contact Dermatitis, May 2016, pages 281-288
- International Journal of Toxicology, September 2013, pages 5S-21S
- Personal Care, 2008, pages 1-4
- Cosmetic Science Technology, 2006, pages 1-11
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Soothing
8 scientific references
- PubChem, Accessed May 2021, ePublication
- Cosmetic Ingredient Review, September 2020, pages 1-38
- Experimental Dermatology, August 2014, pages 553-554
- Journal of Investigative Dermatology, August 2011, pages 526-546
- International Journal of Cosmetic Science, December 2006, pages 447-451
- British Journal of Pharmacology, October 2008, issue 4, pages 475-486
- PloS One, May 2008 (ePublication)
- >International Journal of Cosmetic Science, August 2006, pages 447-451
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
UV filter, Humectant, Emollient, Occlusive, Antioxidant, Plant extract, Preservative
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Camellia Sinensis Leaf Extract is an extract of the leaves of the Tea, Camellia sinensis, Theaceae
Anti-Aging
Soothing
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
L-Arginine
Hydration
Anti-Aging
6 scientific references
- Biobased Surfactants (Second Edition), 2019, pages 413-445
- Scientific Reports, February 2016, pages 1-10
- Cosmetic Ingredient Review, October 2012, pages 1-35
- Journal of Advanced Research, July 2010, pages 169–177
- International Journal of Cosmetic Science, April 2005, page 139
- Wound Repair and Regeneration, November-December 2003, pages 419-423
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Chelator
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cycloheptapentylose
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
.beta.-Cyclodextrin, 2-hydroxypropyl ethers
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Texture agent
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Maltodextrin
Oil Control
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Chelator, pH adjuster
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Hydroxy-1,2,3-propanetricarboxylic acid
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
Hydration
Anti-Aging
Soothing
5 scientific references
- Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
- Journal of Cosmetic Dermatology, July 2014, pages 277-287
- Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
- DermatoEndocrinology, July-December 2012, pages 253-258
- Journal of Drugs in Dermatology, September 2011, pages 990-1000
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Exfoliant, Texture agent
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tin dioxide (CI 77861)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium salt, polymer with 1,1'-sulfonylbis[ethene]
Hydration
Anti-Aging
Soothing
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid
Anti-Aging
Hydration
5 scientific references
- Journal of Evidence-Based, Complementary and Alternative Medicine, October 2017, pages 816-823
- Journal of Medicinal Food, October 2016, pages 1, 172-1, 179
- Nutrition Journal, July 2013, ePublication
- Journal of Drugs in Dermatology, 2011, issue 9, pages 990-1000
- Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38-43
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Antioxidant
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
Anti-Aging
Evens Skin Tone
Soothing
4 scientific references
- Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
- Journal of Investigative Dermatology, November 2001, pages 1212-1217
- Canadian Family Physician, July 2006, pages 855-856
- Dermatologic Surgery, April 1999, pages 311-315
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sodium Acetylhyaluronate
Hydration
Anti-Aging