-
Estimated level
- 10–40%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient
1st on the list, which puts it at an estimated 10–40% of the formula.
3,5,5-Trimethylhexyl 3,5,5-trimethylhexanoate
-
Estimated level
- 5–20%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient
2nd on the list, which puts it at an estimated 5–20% of the formula.
Hexadecyl 2-ethylhexanoate
Hydration
2 scientific references
- Engineering in Life Sciences, March 2019, pages 370-388
- International Journal of Toxicology, Nov-Dec 2015, pages 61S-73S
-
Estimated level
- 5–20%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
UV filter, Texture agent
3rd on the list, which puts it at an estimated 5–20% of the formula.
Titanium dioxide (CI 77891)
Anti-Aging
10 scientific references
- Journal of Cosmetic Dermatology, February 2021, pages 532-537
- Frontiers in Bioengineering and Biotechnology, June 2020
- Journal of Nanoparticle Research, March 2020
- Journal of the European Academy of Dermatology and Venereology, November 2019, pages 34-46
- Photodermatology, Photoimmunology and Photomedicine, November 2019, pages 442-446
- Journal of Cosmetic Science, September 2019, pages 223-234
- Materials, July 2019, pages 1-24
- Photodermatology, Photoimmunology, and Photomedicine, April 2011, pages 58-67
- Skin Therapy Letter, July-August 2008, pages 5-7
- Environmental and Health Perspectives, July 2008, pages 893
-
Estimated level
- 2–10%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Surfactant
4th on the list, which puts it at an estimated 2–10% of the formula.
1,2,3-Propanetriol, homopolymer, isooctadecanoates (1:3) (2 mol glycerol average molar ratio)
-
Estimated level
- 2–10%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Texture agent, Fragrance / colour
5th on the list, which puts it at an estimated 2–10% of the formula.
Mica is a series of silicate minerals of varying chemical composition but with similar physical properties. Mica may have well-defined cleavage and split into very thin sheets.
-
Estimated level
- 2–10%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient, Occlusive
6th on the list, which puts it at an estimated 2–10% of the formula.
Dimethicone
Hydration
Silicone
7 scientific references
- FDA Code of Federal Regulations, April 2020, ePublication
- International Journal of Toxicology, May 2014, pages 65S-115S
- The Journal of Clinical and Aesthetic Dermatology, May 2014, pages 36-44
- Dermatologic Therapy, May 2012, pages 229-233
- Clinics in Dermatology, May-June 2012, pages 345-348
- International Journal of Cosmetic Science, January 2008, pages 19-33
- Skin Research and Technology, May 2000, pages 77-80
-
Estimated level
- 1–5%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient, Texture agent
7th on the list, which puts it at an estimated 1–5% of the formula.
Propene, 2-methyl-, homopolymer
Hydration
4 scientific references
- https://thedermreviewcom/hydrogenated-polyisobutene/
- CosmeticsInfoorg, Accessed March 2021, ePublication
- International Journal of Toxicology, September 2020, pages 59S-90S
- International Journal of Cosmetic Science, February 2010, pages 81-82
-
Estimated level
- 1–5%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Texture agent
8th on the list, which puts it at an estimated 1–5% of the formula.
Ceresin. A complex combination of hydrocarbons produced by the purification of ozocerite with sulfuric acid and filtration through bone black to form waxy cakes
-
Estimated level
- 1–5%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient
9th on the list, which puts it at an estimated 1–5% of the formula.
Hexyl laurate
Hydration
8 scientific references
- Supercharged Hydration
- How Hyaluronic Acid Benefits Skin
- What is Dehydrated Skin & How to Choose the Best Products
- What Your Moisturizer Must Contain
- Moisturizer Myths You Should Stop Believing Now
- The Benefits of Glycerin in Skin Care
- The Best Face Oils for Skin
- How Facial Oils Help Skin
-
Estimated level
- 1–5%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Texture agent
10th on the list, which puts it at an estimated 1–5% of the formula.
Hydrocarbon waxes (petroleum), chemically neutralized. A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists predominantly of saturated straight chain hydrocarbons having carbon numbers predominantly in the range of C20 through C50
-
Estimated level
- 1–3%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Exfoliant, Texture agent
11th on the list, which puts it at an estimated 1–3% of the formula.
Silicon dioxide
Oil Control
6 scientific references
- Advances in Colloid and Interface Science, July 2021, page 10, 2437
- Cosmetic Ingredient Review, October 2019, pages 1-34
- Nanomedicine, August 2019, pages 2, 243-2, 267
- Biological and Pharmaceutical Bulletin, 2016, pages 1, 201-1, 205
- European Journal of Pharmaceutics and Biopharmaceutics, January 2015, pages 116-125
- Cosmetics & Toiletries, April 2015, pages 36-45
-
Estimated level
- 1–3%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Texture agent
12th on the list, which puts it at an estimated 1–3% of the formula.
Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
Silicone
Microplastic
-
Estimated level
- 1–3%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient
13th on the list, which puts it at an estimated 1–3% of the formula.
Hexadecyl hexadecanoate
-
Estimated level
- 1–3%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient, Texture agent
14th on the list, which puts it at an estimated 1–3% of the formula.
Silane, dichlorodimethyl-, reaction products with silica
-
Estimated level
- 1–3%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient, Surfactant
15th on the list, which puts it at an estimated 1–3% of the formula.
Glycerides, mixed decanoyl and octanoyl
-
Estimated level
- 1–3%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Surfactant
16th on the list, which puts it at an estimated 1–3% of the formula.
Sorbitan, (Z)-9-octadecenoate (2:3)
-
Estimated level
- 1–3%
-
Confidence
- Low — inferred from list position alone
17th on the list, which puts it at an estimated 1–3% of the formula.
Decanoic acid, ester with 1,2,3-propanetriol octanoate;
Glycerides, mixed decanoyl and octanoyl
Hydration
5 scientific references
- International Journal of Toxicology, September 2020, pages 34-35
- Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
- International Journal of Toxicology, January 2003, pages 4-5
- Food and Chemical Toxicology, January 2000, pages 79-98
- Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
-
Estimated level
- 1–3%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient
18th on the list, which puts it at an estimated 1–3% of the formula.
Octane-1,2-diol
-
Estimated level
- under 1%
-
Confidence
- Low — inferred from list position alone
19th on the list, which puts it at an estimated under 1% of the formula.
N-[6-[(2-chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl]acetamide
-
Estimated level
- under 1%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient
20th on the list, which puts it at an estimated under 1% of the formula.
Poly[oxy(methylsilylene)]
Hydration
Silicone
-
Estimated level
- under 1%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Surfactant
21st on the list, which puts it at an estimated under 1% of the formula.
12-Hydroxyoctadecanoic acid, homopolymer
-
Estimated level
- under 1%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Occlusive
22nd on the list, which puts it at an estimated under 1% of the formula.
Human Umbilical Blood Derived Natural Killer Cell Conditioned Media is the growth media removed from cultures of human umbilical blood derived natural killer cells after several days of growth. The starting media is Dulbecco's Modified Eagle Medium, and may or may not contain fetal bovine serum.
-
Estimated level
- under 1%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient
23rd on the list, which puts it at an estimated under 1% of the formula.
Hexadecanoic acid, 2-ethylhexyl ester; Octyl palmitate
Hydration
5 scientific references
- Dermatology Clinics and Research, August 2019, pages 239-271
- Clinical Medicine and Research, December 2017, pages 75-87
- International Journal of Toxicology, Volume 34, Issue 2, Supplement, September 2015, pages 5S-69S
- Molecules, February 2015, pages 2, 492-2, 509
- British Journal of Dermatology, October 2010, pages 695-703
-
Estimated level
- under 1%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient, Texture agent
24th on the list, which puts it at an estimated under 1% of the formula.
Tetradecanoic acid, isopropyl ester
Hydration
-
Estimated level
- under 1%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Surfactant, Texture agent
25th on the list, which puts it at an estimated under 1% of the formula.
Isooctadecanoic acid
-
Estimated level
- under 1%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Emollient, Surfactant
26th on the list, which puts it at an estimated under 1% of the formula.
Lecithins. The complex combination of diglycerides of fatty acids linked to the choline ester of phosphoric acid
Hydration
5 scientific references
- Cosmetics, November 2020, pages 1-19
- International Journal of Toxicology, September 2020, pages 5S-25S
- Molecules, March 2020, pages 1-9
- Journal of the American Oil Chemists' Society, March 2014, pages 1, 093-1, 101
- Scientia Pharmaceutica, July 2013, pages 1, 151-1, 166
-
Estimated level
- under 1%
-
Confidence
- Low — inferred from list position alone
-
Roles
-
Surfactant, Texture agent
27th on the list, which puts it at an estimated under 1% of the formula.
9-(Z)-Octadecanoic acid, 12-hydroxy- (9Z, 12R)-, homopolymer, ester with triglycerol