La Roche-Posay  Toleriane Dermallergo Soothing Cream

La Roche-Posay

Toleriane Dermallergo Soothing Cream

face cream

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Fit by skin type

General, ingredient-based — not your personalized match.

Dry
73%
Combination (dry)
73%
Balanced
97%
Combination (oily)
67%
Oily
67%

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20
Ingredients
2
Benefits
1
Actives
Find Dupes

Designed with sensitive skin in mind, the La Roche-Posay Toleriane Dermallergo Cream offers a lightweight, nourishing formula that helps hydrate the skin to reduce the appearance of dryness. Enriched with probiotic-derived fractions and neurosenine, the formula boosts skin with moisture and promotes a visibly balanced appearance. Blended with La Roche-Posay Thermal Spring Water, the cream provides up to 48 hours of hydration and leaves skin feeling soft and supple throughout the day.

Key Insights

Benefits

2
Anti-Aging
Hydration

Active Ingredients

1
AHA

Risks

2
Silicone
Synthetic polymer

About Toleriane Dermallergo Soothing Cream

Overview

Toleriane Dermallergo Soothing Cream is a cushioning cream from La Roche-Posay, a brand based in France. The formula is built mainly around hydration. The ingredient list runs to 20 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as moderately cushioned — emollient enough to feel like a cream, without the heaviest occlusives near the top. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Glycerin, Butylene Glycol and Water, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Butylene Glycol, Water and Squalane.

Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Squalane and Butyrospermum Parkii.

Who it suits

On richness alone it suits Balanced skin best, and is the least natural fit for Dry, Combination (dry), Combination (oily) and Oily skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on antioxidant protection, oil control, brightening and tone and soothing. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after serums. Seal in your serums with it; in the morning, sunscreen still goes on top.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • 4 ingredients could feed malassezia (fungal acne)

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin

Less suitable for

  • Dry skin
  • Combination (dry) skin
  • Combination (oily) skin
  • Oily skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 9 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 3 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

Does not target

Anti-Acne Blackhead Reducing Dark Spot Fading Evens Skin Tone Oil Control Pore Minimizer Smooths Bumpy Skin Soothing

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

3rd on the list, which puts it at an estimated 5–20% of the formula.

2,6,10,15,19,23-Hexamethyltetracosane

Hydration Anti-Aging

5th on the list, which puts it at an estimated 2–10% of the formula.

Dimethicone

Hydration

6th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

8th on the list, which puts it at an estimated 1–5% of the formula.

1,2-Dihydroxypentane

Hydration

9th on the list, which puts it at an estimated 1–5% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration

10th on the list, which puts it at an estimated 1–5% of the formula.

Stearic acid, monoester with glycerol

Hydration

12th on the list, which puts it at an estimated 1–3% of the formula.

Hexadecan-1-ol

Hydration

14th on the list, which puts it at an estimated 1–3% of the formula.

Poly[oxy(dimethylsilylane)], .alpha.-hydro-.omega.-hydroxy-

Hydration

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Hydroxy-1,2,3-propanetricarboxylic acid

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Tyrosine acetate and arginine, hexadecyl ester, dipeptide

Anti-Aging

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration High

Ingredients that pull and hold water in the upper layers of skin

Barrier support Moderate

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control None

Ingredients that moderate sebum or absorb shine

Brightening None

Ingredients that act on uneven tone and post-inflammatory marks

Soothing None

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (1)

Supporting ingredients (19)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Isocetyl Stearate Squalane Butyrospermum Parkii Dimethicone Glycerin ZEA Mays Starch Pentylene Glycol Butylene Glycol Glyceryl Stearate Peg-100 Stearate Cetyl Alcohol Salvia Miltiorrhiza Root Extract Dimethiconol Sodium Hydroxide Sphingomonas Ferment Extract Caprylyl Glycol Acetyl Dipeptide-1 Cetyl Ester Acrylates/c10-30 Alkyl Acrylate Crosspolymer

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • Oil-free
  • No animal-derived ingredients

Contains

  • Silicones

    Dimethicone, Dimethiconol

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Vitamin C (L-ascorbic acid)
  • Retinoids (retinol, retinal)
  • AHAs (glycolic, lactic)
  • BHA (salicylic acid)
  • PHAs (gluconolactone)
  • Benzoyl peroxide
  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Nothing in this formula belongs to a group our rules can put in conflict, so it layers freely. Order still matters — thinnest texture first.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Moisturise" step.

  • Seal in your serums with it; in the morning, sunscreen still goes on top.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Nothing in this formula is on the standard pregnancy-caution list. That is not clearance — ask your doctor about anything you use daily.
Fungal acne (malassezia)
4 ingredients could feed malassezia: Isocetyl Stearate, Butyrospermum Parkii, Glyceryl Stearate, Peg-100 Stearate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 20 ingredients on the label.

7
Emollient

Softens and smooths by filling gaps between skin cells

5
Texture agent

Sets the thickness, spread and stability of the formula

4
Occlusive

Forms a film that slows water loss

4
Solvent

Dissolves and carries everything else

3
Humectant

Draws water into the upper layers of skin

3
Surfactant

Lifts oil and dirt, or holds oil and water together

2
pH adjuster

Sets the acidity the formula needs to work

2
Plant extract

Botanical material, usually for antioxidants or scent

1
Active

Changes how skin behaves rather than how it feels

1
Chelator

Binds trace metals that would otherwise spoil the formula

1
Exfoliant

Loosens or dissolves dead surface cells

1
Peptide

Amino-acid chains that signal for repair or firmness

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

2nd on the list, which puts it at an estimated 5–20% of the formula.

Isohexadecyl stearate

3 Squalane Emollient
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

3rd on the list, which puts it at an estimated 5–20% of the formula.

2,6,10,15,19,23-Hexamethyltetracosane

Hydration Anti-Aging
9 scientific references
  • Cosmetics Ingredient Review, 2019, ePublication
  • ACS Open, July 2017, pages 3, 989–3, 996
  • Indian Journal of Dermatology, May-June 2016, pages 279-297
  • The Journal of Clinical and Aesthetic Dermatology, June 2014, pages 25-32
  • Journal of Cosmetic Science, January-February 2013, pages 59-66
  • Advances in Food and Nutrition Research, 2012, pages 223-233
  • Molecules, January 2009, pages 540-554
  • Journal of Investigative Dermatology, November 2006, pages 2, 430-2, 437
  • Free Radical Research, April 2002, pages 471-477
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line

4th on the list, which puts it at an estimated 2–10% of the formula.

5 Dimethicone Emollient
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Occlusive

5th on the list, which puts it at an estimated 2–10% of the formula.

Dimethicone

Hydration Silicone
7 scientific references
  • FDA Code of Federal Regulations, April 2020, ePublication
  • International Journal of Toxicology, May 2014, pages 65S-115S
  • The Journal of Clinical and Aesthetic Dermatology, May 2014, pages 36-44
  • Dermatologic Therapy, May 2012, pages 229-233
  • Clinics in Dermatology, May-June 2012, pages 345-348
  • International Journal of Cosmetic Science, January 2008, pages 19-33
  • Skin Research and Technology, May 2000, pages 77-80
6 Glycerin Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

6th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
7 ZEA Mays Starch Occlusive
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Occlusive, Exfoliant, Texture agent

7th on the list, which puts it at an estimated 1–5% of the formula.

Zea Mays Starch is a high-polymeric carbohydrate material usually derived from the peeled seeds of the Corn, Zea mays L., Gramineae

Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

8th on the list, which puts it at an estimated 1–5% of the formula.

1,2-Dihydroxypentane

Hydration
4 scientific references
  • https://thedermreviewcom/pentylene-glycol/
  • Regulatory Toxicology and Pharmacology, July 2017, pages 106-111
  • Prospector, June 2015, ePublication
  • International Journal of Toxicology, October 2012, pages 147S-168S
9 Butylene Glycol Humectant
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

9th on the list, which puts it at an estimated 1–5% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
10 Glyceryl Stearate Emollient
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Surfactant

10th on the list, which puts it at an estimated 1–5% of the formula.

Stearic acid, monoester with glycerol

Hydration
3 scientific references
  • Cosmeticsinfoorg, Accessed November 2021, ePublication
  • Drugs in Context, April 2018, pages 1-14
  • International Journal of Toxicology, May 2007, pages 1–30
11 Peg-100 Stearate Surfactant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

11th on the list, which puts it at an estimated 1–3% of the formula.

Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- (100 mol EO average molar ratio)

12 Cetyl Alcohol Emollient
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Surfactant, Texture agent

12th on the list, which puts it at an estimated 1–3% of the formula.

Hexadecan-1-ol

Hydration
3 scientific references
  • International Journal of Cosmetic Science, December 2012, Issue 34, Volume 6, pages 567-74
  • http://wwwcir-safetyorg/sites/default/files/115_buff3a_supplpdf
  • https://pubchemncbinlmnihgov/compound/1-Hexadecanol
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Plant extract

13th on the list, which puts it at an estimated 1–3% of the formula.

Salvia Miltiorrhiza Root Extract is the extract of the roots of the Chinese Sage, Salvia miltiorrhiza, Lamiaceae

14 Dimethiconol Humectant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Emollient

14th on the list, which puts it at an estimated 1–3% of the formula.

Poly[oxy(dimethylsilylane)], .alpha.-hydro-.omega.-hydroxy-

Hydration
3 scientific references
  • CosmeticsInfoorg, Accessed September 2021, ePublication
  • International Journal of Toxicology, November 2017, pages 31S-50S
  • International Journal of Cosmetic Science, April 2005, page 139
15 Sodium Hydroxide pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium hydroxide

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sphingomonas Ferment Extract is an extract of the product obtained by the fermentation of Sphingomonas

17 Caprylyl Glycol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Octane-1,2-diol

18 Citric Acid Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Chelator, pH adjuster

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Hydroxy-1,2,3-propanetricarboxylic acid

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Peptide

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Tyrosine acetate and arginine, hexadecyl ester, dipeptide

Anti-Aging
3 scientific references
  • Pharmaceuticals, July 2021, pages 1–22
  • Journal of Cosmetic Dermatology, June 2020, pages 1, 415–1, 425
  • Journal of the European Academy of Dermatology and Venereology, Supplement 1, February 2016, pages 18–20
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol

Synthetic polymer

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Frequently asked questions

What ingredients are in Toleriane Dermallergo Soothing Cream?

WATER, ISOCETYL STEARATE, SQUALANE, Butyrospermum Parkii, DIMETHICONE, GLYCERIN, ZEA MAYS STARCH, PENTYLENE GLYCOL, BUTYLENE GLYCOL, GLYCERYL STEARATE, PEG-100 STEARATE, CETYL ALCOHOL, SALVIA MILTIORRHIZA ROOT EXTRACT, DIMETHICONOL, SODIUM HYDROXIDE, SPHINGOMONAS FERMENT EXTRACT, CAPRYLYL GLYCOL, CITRIC ACID, ACETYL DIPEPTIDE-1 CETYL ESTER, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER.

What are the active ingredients in Toleriane Dermallergo Soothing Cream?

CITRIC ACID.

How do I use Toleriane Dermallergo Soothing Cream?

Apply this comforting cream morning and evening to face, eye area and neck.

What skin types is Toleriane Dermallergo Soothing Cream good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry), Combination (oily), Oily skin.

Is Toleriane Dermallergo Soothing Cream good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is Toleriane Dermallergo Soothing Cream fungal acne safe?

4 ingredients could feed malassezia: Isocetyl Stearate, Butyrospermum Parkii, Glyceryl Stearate, Peg-100 Stearate. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use Toleriane Dermallergo Soothing Cream while pregnant?

Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.

Is Toleriane Dermallergo Soothing Cream fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does Toleriane Dermallergo Soothing Cream contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is Toleriane Dermallergo Soothing Cream silicone free?

No — it contains Dimethicone, Dimethiconol.

Does Toleriane Dermallergo Soothing Cream contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is Toleriane Dermallergo Soothing Cream paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with Toleriane Dermallergo Soothing Cream?

It layers well with Vitamin C (L-ascorbic acid), Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide.

When should I apply Toleriane Dermallergo Soothing Cream?

Use it morning and evening, after serums.

How many ingredients does Toleriane Dermallergo Soothing Cream have?

It lists 20 ingredients, of which 1 are recorded as actives.

Who makes Toleriane Dermallergo Soothing Cream?

La Roche-Posay, a brand based in France.

Brand
La Roche-Posay
Country
France

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