1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Dr.Melaxin
Cicapyrin Calming Ampoule
face ampoule
Dr.Melaxin
face ampoule
Added Last edited
Fit by skin type
General, ingredient-based — not your personalized match.
See how this fits your skin
Take the skin test and I'll show you how suitable this product is for you.
Take the skin testUnleash the power of calm with the Dr.Melaxin Cicapyrin Calming Ampoule, a skin-soothing solution crafted to restore harmony to irritated, sensitive skin. This potent yet gentle formula harnesses the calming properties of centella asiatica and pycnogenol-rich ingredients to relieve redness, reduce inflammation, and strengthen the skin’s natural barrier. Ideal for those battling flare-ups, post-treatment sensitivity, or environmental stressors, Cicapyrin delivers fast-acting relief in a lightweight, deeply hydrating serum that absorbs effortlessly without residue.
Cicapyrin Calming Ampoule is a lightweight ampoule from Dr.Melaxin. The formula is built mainly around hydration. The ingredient list runs to 46 ingredients, each broken down in full below.
By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Hydration is handled by Butylene Glycol, Glycerin and Propanediol, humectants that pull water into the upper layers of skin rather than sealing it there.
Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Butylene Glycol, Glycerin, Propanediol and Sodium Hyaluronate.
Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Centella Asiatica Leaf Extract, Niacinamide, Xylitol and Sodium Hyaluronate.
Oil control: Moderate. Ingredients that moderate sebum or absorb shine, and here that comes from Niacinamide, Capryloyl Salicylic Acid, Salicylic Acid and Sodium Polyacrylate.
Brightening: Moderate. Ingredients that act on uneven tone and post-inflammatory marks, and here that comes from Niacinamide and Aspergillus Ferment.
On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.
The formula contributes little or nothing on antioxidant protection and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.
Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, silicone-free and microplastic-free. Those claims come from the ingredient list itself, not from the packaging.
It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.
This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.
Drawn purely from the ingredient list
Scored on how rich or light the formula reads from its INCI order.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Based on the curated benefits documented for this product's ingredients.
Attracts and locks in moisture to keep skin plump and dewy
Boosts collagen and cell turnover to reduce fine lines and wrinkles
Calms redness, irritation, and inflammation for sensitive skin
Targets breakouts by reducing bacteria and unclogging pores
Helps unclog pores and reduce blackheads for clearer skin
Regulates sebum production to reduce shine and greasiness
Brightens and balances complexion for a more uniform appearance
Tightens and refines the look of enlarged pores
None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.
The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
3rd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
4th on the list, which puts it at an estimated 2–10% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
5th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
6th on the list, which puts it at an estimated 2–10% of the formula.
1,3-dihydroxypropane
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Propenoic acid, homopolymer, sodium salt
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Xylitol
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Dextrin
Each axis is scored from the ingredients present and how high up the list they sit.
Ingredients that pull and hold water in the upper layers of skin
Lipids and repair signals that support skin barrier integrity
Ingredients that mop up free radicals from UV and pollution
Ingredients that moderate sebum or absorb shine
Ingredients that act on uneven tone and post-inflammatory marks
Ingredients aimed at visible redness and reactivity
Retinoids, acids and enzymes that speed surface turnover
Peptides and growth factors that signal for collagen support
"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.
Solvents, emollients, texture agents and preservatives — the formula that carries the actives.
Read from the full ingredient list. A brand's own claim may differ.
Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
This product is the "Treat" step.
Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.
Most ingredients do more than one job, so these counts add up to more than the 46 ingredients on the label.
Botanical material, usually for antioxidants or scent
Draws water into the upper layers of skin
Sets the thickness, spread and stability of the formula
Changes how skin behaves rather than how it feels
Neutralises free radicals from UV and pollution
Dissolves and carries everything else
Forms a film that slows water loss
Softens and smooths by filling gaps between skin cells
Keeps the product free of microbial growth
Lifts oil and dirt, or holds oil and water together
Binds trace metals that would otherwise spoil the formula
Loosens or dissolves dead surface cells
Sets the acidity the formula needs to work
Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
Denatured Lysozyme is Lysozyme that is denatured through heat treatment.
3rd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
4th on the list, which puts it at an estimated 2–10% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
5th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
6th on the list, which puts it at an estimated 2–10% of the formula.
1,3-dihydroxypropane
7th on the list, which puts it at an estimated 1–5% of the formula.
1-Decanol, 2-octyl-
8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lactid Acid/Glycolic Acid Copolymer is a copolymer of Lactic Acid and Glycolic Acid monomers
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Butane-1,2,3,4-tetrol
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Propenoic acid, homopolymer, sodium salt
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Xylitol
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Poly(oxy-1,2-ethanediyl), .alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris-.omega.-hydroxy-, esters with 5-oxo-L-proline and isooctadecanoic acid (25 mol EO average molar ratio)
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Castor oil (Ricinus communis), hydrogenated, ethoxylated, diesters with isooctadecanoic acid and 2-pyrrolidinone-5-carboxylic acid (60 mol EO average molar ratio)
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Xanthan gum
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,1,2,3,3,6-hexamethylindan-5-yl methyl ketone
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Disodium dihydrogen ethylenediaminetetraacetate
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Theobroma Cacao Seed Extract is the extract of the seeds of the Cocoa, Theobroma cacao L., Sterculiaceae
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Zanthoxylum Schinifolium Fruit Extract is the extract of the fruit of Zanthoxylum schinifolium.
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Aloe Vera Callus Extract is the extract of the callus of Aloe vera grown in culture
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Dioscorea Villosa Root Extract is an extract of the roots of the Wild Yam, Dioscorea villosa L., Dioscoreaceae
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sulfated oligosaccharides obtained from the Seaweed Kelp (Macrocystis pyrifera, Lessoniaceae) hydrolyzate
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Zingiber Officinale Extract is an extract of the roots of the Ginger, Zingiber officinalis L., Zingiberaceae
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1-Hydroxy-4-(p-toluidino)anthraquinone (CI 60725)
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octane-1,2-diol
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Dextrin
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Gardenia Florida Extract is the hydrolysate of Gardenia Florida L., Rubiaceae, Extract derived by acid, enzyme or other method of hydrolysis
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Malt Extract obtained by acid, enzyme or other method of hydrolysis
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Yeast is the hydrolysate of Yeast Extract derived by acid, enzyme or other method of hydrolysis
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Rose Extract is an extract of various species of the Rose, Rosa spp., Rosaceae
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Centella Asiatica Leaf Extract is an extract of the leaves of the Hydrocotyl, Centella asiatica L., Apiaceae
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Benzene, (1-Methylethenyl)-, homopolymer, ar-(2-hydroxy-2-methyl-1-oxopropyl) derivs // Poly(Allyl Phenyl Isopropanol Ketone)
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Eucommia Ulmoides Bark Extract is an extract of the bark of Eucommia ulmoides, Eucommiaceae
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Coral Extract is the extract of the marine invertebrate of the class, Anthozoa.
43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Palau White Clay Extract is the extract of the clay mined in Ngeruktabel Island in Palau
44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Aspergillus Ferment is the product obtained by the fermentation of Aspergillus
45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Benzoic acid, 2-octanoyloxy-
46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Salicylic acid
Products in the same category that share this formula's distinguishing ingredients.
Dr.Melaxin
Shares 12 key ingredients with Cicapyrin Calming Ampoule: Water, Propanediol, Butylene Glycol, Glycerin, Niacinamide
Dr.Melaxin
Shares 12 key ingredients with Cicapyrin Calming Ampoule: Water, Propanediol, Niacinamide, Butylene Glycol, Glycerin
Centellian24
Shares 12 key ingredients with Cicapyrin Calming Ampoule: Water, Glycerin, Propanediol, Niacinamide, Butylene Glycol
Dr.Melaxin
Shares 11 key ingredients with Cicapyrin Calming Ampoule: Water, Butylene Glycol, Glycerin, Niacinamide, Propanediol
Centellian24
Shares 11 key ingredients with Cicapyrin Calming Ampoule: Water, Glycerin, Propanediol, Niacinamide, Butylene Glycol
Biodance
Shares 11 key ingredients with Cicapyrin Calming Ampoule: Water, Glycerin, Propanediol, Niacinamide, Butylene Glycol
WATER, DENATURED LYSOZYME, BUTYLENE GLYCOL, GLYCERIN, NIACINAMIDE, PROPANEDIOL, OCTYLDECANOL, 1,2-HEXANEDIOL, LACTIC ACID/GLYCOLIC ACID COPOLYMER, ERYTHRITOL, SODIUM POLYACRYLATE, XYLITOL, HYDROXYACETOPHENONE, CARBOMER, TROMETHAMINE, SODIUM HYALURONATE, GLYCERETH-25 PCA ISOSTEARATE, PEG-60 HYDROGENATED CASTOR OIL PCA ISOSTEARATE, ETHYLHEXYLGLYCERIN, XANTHAN GUM, ADENOSINE, ACETYL HEXAMETHYL INDAN, DISODIUM EDTA, THEOBROMA CACAO SEED EXTRACT, ZANTHOXYLUM SCHINIFOLIUM FRUIT EXTRACT, ALOE VERA CALLUS EXTRACT, DIOSCOREA VILLOSA ROOT EXTRACT, KELP SULFATED OLIGOSACCHARIDES, ZINGIBER OFFICINALE ROOT EXTRACT, SOLVENT VIOLET 13, CAPRYLYL GLYCOL, DEXTRIN, HYDROLYZED GARDENIA FLORIDA EXTRACT, HYDROLYZED MALT EXTRACT, HYDROLYZED YEAST EXTRACT, ROSE EXTRACT, CENTELLA ASIATICA LEAF EXTRACT, POLY METHYL STYRENE ISOPROPANOL KETONE, EUCOMMIA ULMOIDES BARK EXTRACT, HYALURONIC ACID, HYDROLYZED HYALURONIC ACID, CORAL EXTRACT, PALAU WHITE CLAY EXTRACT, ASPERGILLUS FERMENT, CAPRYLOYL SALICYLIC ACID, SALICYLIC ACID.
NIACINAMIDE, SODIUM HYALURONATE, HYALURONIC ACID, HYDROLYZED HYALURONIC ACID, SALICYLIC ACID.
For best results, apply 2-3 drops of Cicapyrin Calming Ampoule onto clean, toned skin, gently patting it in with fingertips until fully absorbed. Follow with your moisturizer. Tip: For an extra soothing boost, refrigerate the Cicapyrin Calming Ampoule before use.
Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
2 ingredients could feed malassezia: Glycereth-25 PCA Isostearate, Peg-60 Hydrogenated Castor Oil PCA Isostearate. That describes the yeast's food supply, not a prediction that they will cause a breakout.
It contains Salicylic Acid, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.
Yes. Reading the full ingredient list, this formula is fragrance-free.
No. Reading the full ingredient list, this formula is no drying alcohol.
Yes. Reading the full ingredient list, this formula is silicone-free.
No. Reading the full ingredient list, this formula is essential-oil-free.
Yes. Reading the full ingredient list, this formula is paraben-free.
It layers well with Azelaic acid, Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides. Take more care combining it with Retinoids (retinol, retinal), Vitamin C (L-ascorbic acid), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide — use them in separate routines or on alternate days.
Use it morning and evening, after toner, before moisturiser.
It lists 46 ingredients, of which 5 are recorded as actives.
Dr.Melaxin.
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