-
Estimated level
- 30–80%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Hydration
3 scientific references
- Skin Research and Technology, May 2015, pages 131-136
- Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
- Journal of Cosmetic Science, September-October 1993, pages 249-262
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Emollient, Surfactant
2nd on the list, which puts it at an estimated 5–20% of the formula.
Silicones and siloxanes, dimethyl, diphenyl
Silicone
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant
3rd on the list, which puts it at an estimated 5–20% of the formula.
Oxybispropanediol
Hydration
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Emollient, Solvent
4th on the list, which puts it at an estimated 2–10% of the formula.
2-Octyldodecan-1-ol
Hydration
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Emollient, Texture agent
5th on the list, which puts it at an estimated 2–10% of the formula.
Propene, 2-methyl-, homopolymer
Hydration
4 scientific references
- https://thedermreviewcom/hydrogenated-polyisobutene/
- CosmeticsInfoorg, Accessed March 2021, ePublication
- International Journal of Toxicology, September 2020, pages 59S-90S
- International Journal of Cosmetic Science, February 2010, pages 81-82
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
6th on the list, which puts it at an estimated 2–10% of the formula.
1,1,5,5,5-Hexamethyl-3-phenyl-3-[(trimethylsilyl)oxy]trisiloxane
Hydration
Silicone
5 scientific references
- International Journal of Toxicology, 2006, pages 1-89
- https://onlinepersonalcarecouncilorg/ctfa-static/online/lists/cir-pdfs/PRNS513pdf
- Journal of Cosmetic Science, June 2003, pages 335-351
- Silicone Surfactants, 1999, page 190
- International Journal of Toxicology, 1986, pages 353-371
-
Estimated level
- 1–5%
-
Confidence
- Moderate — INCI order above the 1% line
7th on the list, which puts it at an estimated 1–5% of the formula.
1,3-Ccyclopentadiene homopolymer, hydrogenated
-
Estimated level
- 1–5%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Surfactant
8th on the list, which puts it at an estimated 1–5% of the formula.
Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs.
-
Estimated level
- 1–5%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
9th on the list, which puts it at an estimated 1–5% of the formula.
1,2-Dihydroxypentane
Hydration
4 scientific references
- https://thedermreviewcom/pentylene-glycol/
- Regulatory Toxicology and Pharmacology, July 2017, pages 106-111
- Prospector, June 2015, ePublication
- International Journal of Toxicology, October 2012, pages 147S-168S
-
Estimated level
- 1–5%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Surfactant
10th on the list, which puts it at an estimated 1–5% of the formula.
C16-18 alcohols, ethoxylated (20 mol EO average molar ratio)
-
Estimated level
- 1–3%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Emollient
11th on the list, which puts it at an estimated 1–3% of the formula.
Silica, reaction products with trimethylsilane
Hydration
Microplastic
8 scientific references
- Supercharged Hydration
- How Hyaluronic Acid Benefits Skin
- What is Dehydrated Skin & How to Choose the Best Products
- What Your Moisturizer Must Contain
- Moisturizer Myths You Should Stop Believing Now
- The Benefits of Glycerin in Skin Care
- The Best Face Oils for Skin
- How Facial Oils Help Skin
-
Estimated level
- 1–3%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Emollient, Occlusive
12th on the list, which puts it at an estimated 1–3% of the formula.
Dimethicone
Hydration
Silicone
7 scientific references
- FDA Code of Federal Regulations, April 2020, ePublication
- International Journal of Toxicology, May 2014, pages 65S-115S
- The Journal of Clinical and Aesthetic Dermatology, May 2014, pages 36-44
- Dermatologic Therapy, May 2012, pages 229-233
- Clinics in Dermatology, May-June 2012, pages 345-348
- International Journal of Cosmetic Science, January 2008, pages 19-33
- Skin Research and Technology, May 2000, pages 77-80
-
Estimated level
- 1–3%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Plant extract
13th on the list, which puts it at an estimated 1–3% of the formula.
Mel Extract (EU)
Hydration
Soothing
-
Estimated level
- 1–3%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Texture agent
14th on the list, which puts it at an estimated 1–3% of the formula.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium hydroxyethyl acrylate and acryloyldimethyl taurate monomers
Synthetic polymer
-
Estimated level
- 1–3%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Emollient
15th on the list, which puts it at an estimated 1–3% of the formula.
2,6,10,15,19,23-Hexamethyltetracosane
Hydration
Anti-Aging
9 scientific references
- Cosmetics Ingredient Review, 2019, ePublication
- ACS Open, July 2017, pages 3, 989–3, 996
- Indian Journal of Dermatology, May-June 2016, pages 279-297
- The Journal of Clinical and Aesthetic Dermatology, June 2014, pages 25-32
- Journal of Cosmetic Science, January-February 2013, pages 59-66
- Advances in Food and Nutrition Research, 2012, pages 223-233
- Molecules, January 2009, pages 540-554
- Journal of Investigative Dermatology, November 2006, pages 2, 430-2, 437
- Free Radical Research, April 2002, pages 471-477
-
Estimated level
- 1–3%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Occlusive, Texture agent
16th on the list, which puts it at an estimated 1–3% of the formula.
Cellulose, ethyl ether
-
Estimated level
- 1–3%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Surfactant
17th on the list, which puts it at an estimated 1–3% of the formula.
Siloxanes and Silicones, dodecyl methyl, 2-trimethylsilylpoly(oxydimethylsilyl)ethyl methyl, dimethyl
Silicone
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
Hydration
5 scientific references
- PLoS One, October 2016, ePublication
- Contact Dermatitis, May 2016, pages 281-288
- International Journal of Toxicology, September 2013, pages 5S-21S
- Personal Care, 2008, pages 1-4
- Cosmetic Science Technology, 2006, pages 1-11
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Chelator
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
L-Aspartic acid, N,N'-1,2-ethanediylbis-, trisodium salt
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sorbitan, isooctadecanoate
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Emollient, Occlusive, Texture agent
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Aluminium hydroxide
Oil Control
8 scientific references
- Oil-Absorbing Ingredients
- Help for Oily Skin
- Salicylic Acid for Skin
- How BHA Exfoliants Work
- Which BHA Exfoliant is Right for Me?
- Niacinamide Benefits: What Does Niacinamide Do for Skin?
- The Best Toners for Oily Skin
- The Best Moisturizers for Oily, Acne-Prone Skin
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Surfactant
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Propenoic acid, homopolymer, ammonium salt
Synthetic polymer
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Texture agent, Solvent
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7)
(R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Hydration
5 scientific references
- CosmeticsInfoorg, Accessed March 2021, ePublication
- US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
- International Journal of Toxicology, May 2011, pages 5S-16S
- Skin Research and Technology, November 2007, pages 417-24
- Journal of the American College of Toxicology, September 1985, pages 223-248
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent, Solvent
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-dihydroxypropane
Hydration
4 scientific references
- PubChem Compound Summary, April 2021, ePublication
- SpecialChem, Accessed April 2021, ePublication
- Cosmetic Ingredient Review, June 2018, pages 1-73
- Cosmetics & Toiletries, May 2013, pages 81-86
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Solvent
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Antioxidant
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
Anti-Aging
Evens Skin Tone
Soothing
4 scientific references
- Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
- Journal of Investigative Dermatology, November 2001, pages 1212-1217
- Canadian Family Physician, July 2006, pages 855-856
- Dermatologic Surgery, April 1999, pages 311-315
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Antioxidant, pH adjuster
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ascorbic acid
Anti-Aging
Dark Spot Fading
Evens Skin Tone
12 scientific references
- Drug Delivery, February 2021, pages 445-453
- Journal of Cosmetic Dermatology, December 2020, pages 3, 262-3, 269
- Journal of Oral and Maxillofacial Pathology, May-August 2020, pages 374-382
- Journal of Cosmetic Dermatology, March 2020, pages 671-676
- Journal of Clinical and Aesthetic Dermatology, July 2017 pages 14-17
- Journal of Drugs in Dermatology, July 2016, pages 863-867
- Clinical, Cosmetic, and Investigational Dermatology, September 2015, pages 463-470
- Indian Dermatology Online Journal, April-June 2013, pages 143-146
- AAPS PharmSciTech, July 2011, pages 917-923
- Journal of Drugs in Dermatology, July 2008, Supplement, pages s2-s6
- International Journal of Toxicology, Supplement 2, March 2005, pages 51-111
- Skin Pharmacology and Physiology, July-August 2004, pages 200-206
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, [3aS-(3a.alpha.,4.beta.,6a.alpha.)]-
Anti-Aging
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cyanocobalamin; Vitamine B12
Anti-Aging
8 scientific references
- 5 Super Anti-Aging Antioxidants Your Skin Needs
- How to Keep Your Neck & Chest Looking Young
- Acne & Aging Skin
- How to Diminish Uneven Skin Tone and Get Your Glow Back
- What Are Peptides and What Do They Do for Skin?
- The Truth About Firming Creams
- Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
- Anti-Aging Superstars
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Folic acid
Anti-Aging
8 scientific references
- 5 Super Anti-Aging Antioxidants Your Skin Needs
- How to Keep Your Neck & Chest Looking Young
- Acne & Aging Skin
- How to Diminish Uneven Skin Tone and Get Your Glow Back
- What Are Peptides and What Do They Do for Skin?
- The Truth About Firming Creams
- Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
- Anti-Aging Superstars
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
Soothing
Anti-Aging
Pore Minimizer
15 scientific references
- International Journal of Dermatology, February 2021, pages 166-173
- Biomolecules & Therapeutics, July 2019, pages 562-569
- Experimental Dermatology, February 2019, pages 15-22
- Dermatologic Therapy, September 2017, ePublication
- Journal of Investigative Dermatology, May 2017, page S116
- International Journal of Pharmaceutics, March 2017, pages 158-162
- Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
- Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
- Skin Pharmacology and Physiology, June 2014, pages 311-315
- International Journal of Pharmacy, January 2013, pages 192-201
- Dermatoendrocrinology, July 2012, pages 308-319
- International Journal of Toxicology, September 2005, pages 1-31
- Dermatologic Surgery, July 2005, pages 860-865
- International Journal of Cosmetic Science, October 2004, pages 231-238
- Journal of Cosmetic Dermatology, April 2004, pages 88-93
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Propanoic acid, 3-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino-, (R)-
Hydration
Soothing
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-; vitamine B6
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Riboflavin
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
Anti-Aging
8 scientific references
- 5 Super Anti-Aging Antioxidants Your Skin Needs
- How to Keep Your Neck & Chest Looking Young
- Acne & Aging Skin
- How to Diminish Uneven Skin Tone and Get Your Glow Back
- What Are Peptides and What Do They Do for Skin?
- The Truth About Firming Creams
- Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
- Anti-Aging Superstars
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Soothing
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Flavonoids, lemon oil
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycine, N-(N-L-.gamma.-glutamyl-L-cysteinyl)-
Anti-Aging
8 scientific references
- Journal of Cosmetic Dermatology, June 2019, pages 728–737
- Clinical Cosmetic and Investigative Dermatology, April 2017, pages 147-153 and October 2014, pages 267-274
- Nutrients, August 2017, pages 1-27
- DermatoEndocrinology, July 2012, pages 308-319
- Journal of Agricultural and Food Chemistry, 2011, pages 3, 940-3, 949
- The Dermatologist, October 2011, volume 19, issue 10
- Journal of Dermatologic Science, May 2010, pages 85-90
- Free Radical Biology and Medicine, October 1994, pages 333-349
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient, Surfactant
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
9,12-Octadecadienoic acid (9Z, 12Z)-
Anti-Aging
Hydration
6 scientific references
- https://wwwcir-safetyorg/sites/default/files/facids042019finalreppdf
- Clinical, Cosmetic and Investigational Dermatology, January 2018, pages 21-28
- https://thedermreviewcom/linoleic-acid/
- Dermatology Research and Practice, 2012, pages 9231-9234
- Archives of Dermatological Research, 1998, issue 7, pages 375-381
- Clinical and Experimental Dermatology, 1998, issue 2, pages 56-58
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,4-Naphthalenedione, 2-methyl-; Vitamin K3
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Retinol; vitamin A
Anti-Aging
Anti-Acne
Pore Minimizer
Pregnancy Unsafe
10 scientific references
- Journal of Drugs in Dermatology, September 2019, pages 918-923; and March 2015, pages 271-280
- Experimental Dermatology, August 2019, pages 906-913
- Archives of Dermatological Research, May 2017, pages 275-283
- International Journal of Cosmetic Science, February 2017, pages 56-65
- Dermatology, May 2014, pages 314-325
- Dermatoendocrinology, July 2012, issue 3, pages 308-319
- Toxicological Research, March 2010, pages 61-66
- Archives of Dermatology, May 2007, pages 606-612
- The Journal of Pathology, January 2007, issue 2, pages 241-251
- Clinical Interventions in Aging, December 2006, pages 327-348
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Preservative
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Phenoxyethanol
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
UV filter, Texture agent
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Titanium dioxide (CI 77891)
Anti-Aging
10 scientific references
- Journal of Cosmetic Dermatology, February 2021, pages 532-537
- Frontiers in Bioengineering and Biotechnology, June 2020
- Journal of Nanoparticle Research, March 2020
- Journal of the European Academy of Dermatology and Venereology, November 2019, pages 34-46
- Photodermatology, Photoimmunology and Photomedicine, November 2019, pages 442-446
- Journal of Cosmetic Science, September 2019, pages 223-234
- Materials, July 2019, pages 1-24
- Photodermatology, Photoimmunology, and Photomedicine, April 2011, pages 58-67
- Skin Therapy Letter, July-August 2008, pages 5-7
- Environmental and Health Perspectives, July 2008, pages 893
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Disodium 5-amino-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate (CI 17200)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-(2-amino-4-nitroanilino)ethanol
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
4-(2',3'-Dihydroxypropyl)amino-3-nitro-trifluoromethylbenzene
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Fragrance / colour
46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
9,10-Anthracenedione, 1,4,5,8-tetraamino-