-
Estimated level
- 30–80%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Hydration
3 scientific references
- Skin Research and Technology, May 2015, pages 131-136
- Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
- Journal of Cosmetic Science, September-October 1993, pages 249-262
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Occlusive, Texture agent, Solvent
2nd on the list, which puts it at an estimated 5–20% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
Hydration
Anti-Aging
6 scientific references
- Journal of Pharmaceutical Investigation, March 2021, pages 223-231
- International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
- International Journal of Cosmetic Science, August 2016, ePublication
- British Journal of Dermatology, July 2008, pages 23-34
- Journal of Cosmetic Dermatology, June 2007, pages 75-82
- Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Texture agent, Solvent
3rd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7)
(R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Hydration
5 scientific references
- CosmeticsInfoorg, Accessed March 2021, ePublication
- US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
- International Journal of Toxicology, May 2011, pages 5S-16S
- Skin Research and Technology, November 2007, pages 417-24
- Journal of the American College of Toxicology, September 1985, pages 223-248
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
4th on the list, which puts it at an estimated 2–10% of the formula.
2-Methyl-1,3-propanediol
Hydration
3 scientific references
- PubChem, Accessed April 2021, ePublication
- Cosmetic Ingredient Review, June 2018, pages 1-73
- Contact Dermatitis, September 2017, pages 159-162
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Active
5th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
Soothing
Anti-Aging
Pore Minimizer
15 scientific references
- International Journal of Dermatology, February 2021, pages 166-173
- Biomolecules & Therapeutics, July 2019, pages 562-569
- Experimental Dermatology, February 2019, pages 15-22
- Dermatologic Therapy, September 2017, ePublication
- Journal of Investigative Dermatology, May 2017, page S116
- International Journal of Pharmaceutics, March 2017, pages 158-162
- Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
- Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
- Skin Pharmacology and Physiology, June 2014, pages 311-315
- International Journal of Pharmacy, January 2013, pages 192-201
- Dermatoendrocrinology, July 2012, pages 308-319
- International Journal of Toxicology, September 2005, pages 1-31
- Dermatologic Surgery, July 2005, pages 860-865
- International Journal of Cosmetic Science, October 2004, pages 231-238
- Journal of Cosmetic Dermatology, April 2004, pages 88-93
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
6th on the list, which puts it at an estimated 2–10% of the formula.
Irish Moss
Hydration
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Solvent
7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Keratins. Natural, fibrous proteins occurring in vertebrates. They contain all of the common amino acids and are characterized by high cystine content
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant, Texture agent
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Xanthan gum
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Fluorphlogopite, Mg3K[AlF2O(SiO3)3] (synthetic)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Solvent
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Dihydroxypentane
Hydration
4 scientific references
- https://thedermreviewcom/pentylene-glycol/
- Regulatory Toxicology and Pharmacology, July 2017, pages 106-111
- Prospector, June 2015, ePublication
- International Journal of Toxicology, October 2012, pages 147S-168S
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
UV filter, Texture agent
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Titanium dioxide (CI 77891)
Anti-Aging
10 scientific references
- Journal of Cosmetic Dermatology, February 2021, pages 532-537
- Frontiers in Bioengineering and Biotechnology, June 2020
- Journal of Nanoparticle Research, March 2020
- Journal of the European Academy of Dermatology and Venereology, November 2019, pages 34-46
- Photodermatology, Photoimmunology and Photomedicine, November 2019, pages 442-446
- Journal of Cosmetic Science, September 2019, pages 223-234
- Materials, July 2019, pages 1-24
- Photodermatology, Photoimmunology, and Photomedicine, April 2011, pages 58-67
- Skin Therapy Letter, July-August 2008, pages 5-7
- Environmental and Health Perspectives, July 2008, pages 893
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Texture agent
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cellulose, carboxymethyl ether, sodium salt
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Potassium chloride
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Soothing
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sucrose
Hydration
8 scientific references
- Supercharged Hydration
- How Hyaluronic Acid Benefits Skin
- What is Dehydrated Skin & How to Choose the Best Products
- What Your Moisturizer Must Contain
- Moisturizer Myths You Should Stop Believing Now
- The Benefits of Glycerin in Skin Care
- The Best Face Oils for Skin
- How Facial Oils Help Skin
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Soothing
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Urea, (2,5-dioxo-4-imidazolidinyl)-
Soothing
8 scientific references
- Chemistry Series, March 2020, pages 7-21
- Molecules, June 2019, pages 1-33
- European Journal of Pharmacology, February 2018, pages 68-78
- Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
- Pharmacognosy Review, Volume 5, July-December 2011
- International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
- Journal of Occupational Medicine and Toxicology, October 2008, ePublication
- https://wwwaccessdatafdagov/scripts/cdrh/cfdocs/cfcfr/CFRSearchcfm?CFRPart=347&showFR=1
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
Hydration
5 scientific references
- PLoS One, October 2016, ePublication
- Contact Dermatitis, May 2016, pages 281-288
- International Journal of Toxicology, September 2013, pages 5S-21S
- Personal Care, 2008, pages 1-4
- Cosmetic Science Technology, 2006, pages 1-11
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Soothing
8 scientific references
- PubChem, Accessed May 2021, ePublication
- Cosmetic Ingredient Review, September 2020, pages 1-38
- Experimental Dermatology, August 2014, pages 553-554
- Journal of Investigative Dermatology, August 2011, pages 526-546
- International Journal of Cosmetic Science, December 2006, pages 447-451
- British Journal of Pharmacology, October 2008, issue 4, pages 475-486
- PloS One, May 2008 (ePublication)
- >International Journal of Cosmetic Science, August 2006, pages 447-451
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Chelator
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Myo-Inositol, hexakis(dihydrogen phosphate), sodium salt
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3-O-Ethyl Ascorbic Acid is the organic compound.
Anti-Aging
Evens Skin Tone
Dark Spot Fading
5 scientific references
- Free Radical Biology and Medicine, September 2021, pages 151–169
- Life, May 2021, pages 1–13
- International Journal of Pharmaceutics, December 2019, pages 1–9
- Journal of Cosmetic Science, July-August 2018, pages 233–243
- AAPS PharmSciTech, June 2016, pages 767–777
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
Hydration
Soothing
7 scientific references
- The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
- International Journal of Cosmetic Science, December 2019, pages 534-547
- Journal of Cosmetic Dermatology, January 2019, pages 346-354
- Cosmetic Ingredient Review, March 2018, pages 1-51
- The Journal of Dermatological Treatment, August 2017, pages 173-180
- Journal of Cosmetic Science, August 2011, pages 361-370
- American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
alpha-D-Glucopyranoside, 2-Hydroxy-1-(Hydroxymethyl)ethyl
Hydration
Soothing
4 scientific references
- Health Science Reports, April 2021, pages 1–7
- Antioxidants, February 2020, pages 1–20
- The Journal of Clinical and Aesthetic Dermatology, August 2012, pages 29–39
- Skin Pharmacology and Physiology, May 2012, pages 192–199
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Surfactant, Preservative
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Product obtained by the fermentation of glucose and methyl rapeseedate by the microorganism Candida bombicola
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ester of hexaglycerol and caprylic acid
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2,3-Propanetriol, homopolymer, decanoates (1:1) (4 mol glycerol average molar ratio)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Fragrance / colour
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Parfum is a term for ingredient labelling used to identify that a product contains a material or a combination of materials normally added to a cosmetic to produce or to mask a particular odour. According to Article 19 of the Cosmetics Regulation, 'Perfume and aromatic compositions and their raw materials shall be referred to by the terms ‘parfum’ or ‘aroma’. '
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent, Solvent
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Helianthus Annuus Seed Oil is the oil expressed from the seeds of the Sunflower, Helianthus annuus L., Compositae
Anti-Aging
Hydration
4 scientific references
- Pediatric Dermatology, August 2018, ePublication; and January-February 2013, pages 42-50
- Chemicke Zvesti, May 2018, pages 2, 607-2, 615
- International Journal of Molecular Sciences, December 2017, ePublication
- Dermatology, October 2014, pages 230-239
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagens. A fibrous protein comprising one third of the total protein in mammalian organisms. It is a polypeptide containing three peptide chains and rich in proline and hydroxyproline
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine
Hydration
Anti-Aging
11 scientific references
- International Journal of Toxicology, 2020, pages 5S-25S
- International Journal of Molecular Sciences, August 2019, pages 1-15
- Skin Pharmacology and Physiology, 2016, pages 135-147
- Biochimica et Biophysica Acta, October 2014, pages 2473-2483
- Journal of the American Academy of Dermatology, July 2014, pages 177-184
- Journal of Lipid Research, July 2008, pages 1, 466-1, 476
- Journal of Lipid Research, September 2007, pages 1936-1943
- American Journal of Clinical Dermatology, 2003, pages 107-129
- Contact Dermatitis, June 2002, pages 331-338
- Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
- Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Antioxidant
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
Anti-Aging
Evens Skin Tone
Soothing
4 scientific references
- Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
- Journal of Investigative Dermatology, November 2001, pages 1212-1217
- Canadian Family Physician, July 2006, pages 855-856
- Dermatologic Surgery, April 1999, pages 311-315
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Plant extract
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagen Extract is an oil-soluble extract of Collagen
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-22 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Transforming Growth Factor Beta 1. It contains a maximum of 390 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-1 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Basic Fibroblast Growth Factor used as such or adapted to the production host. It contains a maximum of 288 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Epidermal Growth Factor. It contains a maximum of 53 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
It is a single chain recombinant human peptide,produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Insulin-Like Growth Factor used as such or adapted to the production host.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
It is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Keratinocyte Growth Factor used as such or adapted to the production host.