Dr. Althea 345 Relief Cream

Dr. Althea

345 Relief Cream

face cream

Added Last edited

Fit by skin type

General, ingredient-based — not your personalized match.

Dry
49%
Combination (dry)
49%
Balanced
79%
Combination (oily)
91%
Oily
91%

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38
Ingredients
6
Benefits
4
Actives
Find Dupes

The Dr. Althea 345 Relief Cream is a regenerating cream designed to nourish, soothe, and repair the skin barrier, especially after breakouts, irritation, or cosmetic procedures. Lightweight and non-greasy, it delivers multi-layered hydration and calming care without clogging pores. Ideal for dry or sensitized skin types.

Key Insights

Benefits

6
Anti-Aging
Dark Spot Fading
Evens Skin Tone
Hydration
Pore Minimizer
Soothing

Active Ingredients

4
Ceramides Hyaluronic acid Vitamin B3 (niacinamide) Vitamin B5 (panthenol)

Risks

3
Microplastic
Silicone
Synthetic polymer

About 345 Relief Cream

Overview

345 Relief Cream is a watery-light cream from Dr. Althea, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 38 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as very light — essentially a water-and-humectant base with little emollient weight. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Propanediol, Glycerin and Panthenol, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Propanediol, Glycerin, Panthenol and Butylene Glycol.

Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Panthenol, Centella Asiatica Leaf Water, Beta-glucan and Madecassoside.

Who it suits

On richness alone it suits Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on cell renewal and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, sulfate-free and dye-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after serums. Seal in your serums with it; in the morning, sunscreen still goes on top.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • Strong humectant content for hydration
  • No common irritants flagged in the list
  • No recognised malassezia (fungal acne) triggers

Things to know

  • Contains a solid synthetic polymer (microplastic)

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Combination (oily) skin
  • Oily skin

May suit

  • Balanced skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 17 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 10 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 8 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Dark Spot Fading 1 ingredient

    Fades hyperpigmentation and evens out dark spots over time

  • Evens Skin Tone 1 ingredient

    Brightens and balances complexion for a more uniform appearance

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

Does not target

Anti-Acne Blackhead Reducing Oil Control Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

3rd on the list, which puts it at an estimated 5–20% of the formula.

1,3-dihydroxypropane

Hydration

4th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

6th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1-Decene, homopolymer, hydrogenated

Hydration
Niacinamide Vitamin B3 (niacinamide)

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration
Panthenol Vitamin B5 (panthenol)

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Carbonic Acid, Dicaprylyl Ester

Hydration

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of ammonium acryloyldimethyltaurate and vinylpyrrolidone monomers

Hydration

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,1,3,5,5,5-Heptamethyl-3-octyl-trisiloxane

Hydration

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone

Anti-Aging Hydration

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-(N,N,N-Trimethylamino)ethyl 2-(2-methyl-2-propenoyloxy)ethyl phosphate inner salt, polymer with butyl 2-methyl-2-propenoate

Hydration

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration High

Ingredients that pull and hold water in the upper layers of skin

Barrier support Low

Lipids and repair signals that support skin barrier integrity

Antioxidant support Low

Ingredients that mop up free radicals from UV and pollution

Oil control Low

Ingredients that moderate sebum or absorb shine

Brightening Low

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Moderate

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (5)

Supporting ingredients (33)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Aqua Melaleuca Alternifolia Leaf Water Propanediol Glycerin 1,2-hexanediol Hydrogenated Polydecene Vinyl Dimethicone C14-22 Alcohols Caprylic/capric Triglyceride Dicaprylyl Carbonate Butylene Glycol Ammonium Acryloyldimethyltaurate/vp Copolymer Caprylyl Methicone Polymethylsilsesquioxane C12-20 Alkyl Glucoside Hydroxyacetophenone Acrylates/c10-30 Alkyl Acrylate Crosspolymer Polyquaternium-51 Ethylhexylglycerin Tromethamine Sodium Stearoyl Glutamate Coptis Japonica Root Extract Centella Asiatica Leaf Water Beta-glucan Resveratrol Camellia Sinensis Leaf Water Tocopherol Madecassoside Sodium DNA Centella Asiatica Extract Tannic Acid Disodium Edta Sodium Phytate

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Sulfate-free
  • Dye-free
  • Oil-free
  • No animal-derived ingredients

Contains

  • Silicones

    Vinyl Dimethicone, Caprylyl Methicone, Polymethylsilsesquioxane

  • Microplastics

    Polymethylsilsesquioxane

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Vitamin C (L-ascorbic acid)
  • Retinoids (retinol, retinal)
  • AHAs (glycolic, lactic)
  • BHA (salicylic acid)
  • PHAs (gluconolactone)
  • Benzoyl peroxide
  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Nothing in this formula belongs to a group our rules can put in conflict, so it layers freely. Order still matters — thinnest texture first.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Moisturise" step.

  • Seal in your serums with it; in the morning, sunscreen still goes on top.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Nothing in this formula is on the standard pregnancy-caution list. That is not clearance — ask your doctor about anything you use daily.
Fungal acne (malassezia)
No ingredient here is a recognised food source for malassezia.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Microplastic, Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 38 ingredients on the label.

9
Texture agent

Sets the thickness, spread and stability of the formula

6
Solvent

Dissolves and carries everything else

5
Active

Changes how skin behaves rather than how it feels

5
Plant extract

Botanical material, usually for antioxidants or scent

4
Antioxidant

Neutralises free radicals from UV and pollution

4
Humectant

Draws water into the upper layers of skin

4
Occlusive

Forms a film that slows water loss

3
Surfactant

Lifts oil and dirt, or holds oil and water together

2
Emollient

Softens and smooths by filling gaps between skin cells

2
Chelator

Binds trace metals that would otherwise spoil the formula

1
Soothing

Calms visible redness and irritation

1
pH adjuster

Sets the acidity the formula needs to work

1
Preservative

Keeps the product free of microbial growth

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Aqua Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Water

Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Plant extract, Preservative

2nd on the list, which puts it at an estimated 5–20% of the formula.

Melaleuca Alternifolia Leaf Water is an aqueous solution of the steam distillates obtained from the leaves of the Tea Tree, Melaleuca alternifolia, Myrtaceae

3 Propanediol Texture agent
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

1,3-dihydroxypropane

Hydration
4 scientific references
  • PubChem Compound Summary, April 2021, ePublication
  • SpecialChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Cosmetics & Toiletries, May 2013, pages 81-86
4 Glycerin Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

4th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

5th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Solvent

6th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1-Decene, homopolymer, hydrogenated

Hydration
7 Vinyl Dimethicone Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Silicones and siloxanes, dimethyl, ethenyl methyl, ethenyldimethylsilyl terminated

Silicone
8 C14-22 Alcohols Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

C14-22 Alcohols is a mixture of synthetic fatty alcohols with 14 to 22 carbons in the alkyl chain

9 Niacinamide Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration
5 scientific references
  • International Journal of Toxicology, September 2020, pages 34-35
  • Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
  • International Journal of Toxicology, January 2003, pages 4-5
  • Food and Chemical Toxicology, January 2000, pages 79-98
  • Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
11 Panthenol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Carbonic Acid, Dicaprylyl Ester

Hydration
5 scientific references
  • OCL, April 2018, pages 1-10
  • Journal of Surfactants and Detergents, July 2017, pages 1, 337–1, 349
  • Cosmetic Ingredient Review, December 2016, pages 1-50
  • https://wwwcir-safetyorg/sites/default/files/dialkyl%20carbonatespdf
  • https://wwwulprospectorcom/en/na/PersonalCare/Detail/75/204256/Cetiol-CC
13 Butylene Glycol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Texture agent, Solvent

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of ammonium acryloyldimethyltaurate and vinylpyrrolidone monomers

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,1,3,5,5,5-Heptamethyl-3-octyl-trisiloxane

Hydration Silicone
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Polymer formed by hydrolysis and condensation of methyltrimethoxysilane

Microplastic
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

C12-20 Alkyl Glucoside is the product obtained by the condensation of C12-20 alcohols with glucose

18 Hydroxyacetophenone Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone

Anti-Aging Hydration
4 scientific references
  • Journal of Oleo Science, February 2019, pages 183-191
  • Applied Environmental Microbiology, June 2018, ePublication
  • Journal of Biosciences, May-June 2004, pages 345-353
  • Scientific Reports, April 2021, pages 1–7
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol

Synthetic polymer
20 Polyquaternium-51 Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-(N,N,N-Trimethylamino)ethyl 2-(2-methyl-2-propenoyloxy)ethyl phosphate inner salt, polymer with butyl 2-methyl-2-propenoate

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
22 Tromethamine pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium hydrogen N-(1-oxooctadecyl)-L-glutamate

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Coptis Japonica Root Extract is an extract of the roots of Coptis japonica, Ranunculaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Centella Asiatica Leaf Water is an aqueous solution of the steam distillate obtained from the leaves of Hydrocotyl, Centella asiatica L., Apiaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

beta-Glucan is a polysaccharide consisting of b(1-3) linked glucose chains carrying b(1-6) linked glucose sidechains

Soothing Hydration
6 scientific references
  • Journal of Cosmetic Dermatology, December 2018, pages 1, 101-1, 107
  • International Journal of Molecular Sciences, September 2017, pages 1-48
  • Phytotherapy Research, February 2014, pages 159-166
  • Cosmetic Ingredient Review, October 2012, pages 1-52
  • Journal of Drugs in Dermatology, February 2007, pages 167-170
  • International Journal of Cosmetic Science, October 2005, page 292
28 Resveratrol Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Antioxidant

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Benzenediol, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-

Anti-Aging Dark Spot Fading Soothing
8 scientific references
  • Biomedicine and Pharmacotherapy, November 2021, ePublication
  • International Journal of Molecular Sciences, October 2021, pages 1–26
  • Phytotherapy Research, March 2020, pages 435–447
  • Biomolecules and Therapeutics, October 2018, pages 1–14
  • Journal of Cosmetic and Laser Therapy, May 2018 ePublication
  • Journal of Drugs in Dermatology, December 2013, pages 1389-1394
  • Archives of Biochemistry and Biophysics, April 2011, pages 164-170
  • Antioxidants and Redox Signaling, December 2001, pages 1041-1064
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Camellia Sinensis Leaf Water is an aqueous solution of the odoriferous principles of the leaves of the Tea, Camellia sinensis, Theaceae

31 Tocopherol Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E

Anti-Aging Evens Skin Tone Soothing
4 scientific references
  • Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
  • Journal of Investigative Dermatology, November 2001, pages 1212-1217
  • Canadian Family Physician, July 2006, pages 855-856
  • Dermatologic Surgery, April 1999, pages 311-315
32 Madecassoside Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

O-6-Deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oate

Anti-Aging Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Deoxyribonucleic acid, sodium salts

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing, Surfactant, Plant extract

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae

Soothing Anti-Aging
6 scientific references
  • Phytomedicine, April 2018, pages 110–119
  • Clinical, Cosmetic, and Investigational Dermatology, August 2017, pages 311–315
  • Indian Journal of Pharmaceutical Sciences, Jan-Feb 2016, pages 27–33
  • Postepy Dermatologii I, February 2013, pages 46–49
  • Indian Journal of Pharmaceutical Sciences, 2010, pages 546–556
  • Scientific Reports, June 2021, ePublication
35 Ceramide NP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Hydration Anti-Aging
11 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Tannins. Gallic acid derivatives found in nutgalls, bark and other plant parts, especially oak bark

Anti-Aging
37 Disodium Edta Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Chelator

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Disodium dihydrogen ethylenediaminetetraacetate

38 Sodium Phytate Chelator
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Chelator

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Myo-Inositol, hexakis(dihydrogen phosphate), sodium salt

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Frequently asked questions

What ingredients are in 345 Relief Cream?

AQUA, MELALEUCA ALTERNIFOLIA LEAF WATER, PROPANEDIOL, GLYCERIN, 1,2-HEXANEDIOL, HYDROGENATED POLYDECENE, VINYL DIMETHICONE, C14-22 ALCOHOLS, NIACINAMIDE, CAPRYLIC/CAPRIC TRIGLYCERIDE, PANTHENOL, DICAPRYLYL CARBONATE, BUTYLENE GLYCOL, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, CAPRYLYL METHICONE, POLYMETHYLSILSESQUIOXANE, C12-20 ALKYL GLUCOSIDE, HYDROXYACETOPHENONE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, POLYQUATERNIUM-51, ETHYLHEXYLGLYCERIN, TROMETHAMINE, SODIUM HYALURONATE, SODIUM STEAROYL GLUTAMATE, COPTIS JAPONICA ROOT EXTRACT, CENTELLA ASIATICA LEAF WATER, BETA-GLUCAN, RESVERATROL, HYDROLYZED HYALURONIC ACID, CAMELLIA SINENSIS LEAF WATER, TOCOPHEROL, MADECASSOSIDE, SODIUM DNA, CENTELLA ASIATICA EXTRACT, CERAMIDE NP, TANNIC ACID, DISODIUM EDTA, SODIUM PHYTATE.

What are the active ingredients in 345 Relief Cream?

NIACINAMIDE, PANTHENOL, SODIUM HYALURONATE, HYDROLYZED HYALURONIC ACID, CERAMIDE NP.

How do I use 345 Relief Cream?

Wash your face with a gentle cleanser suited for your skin type. Apply less viscous skincare products like toner first. Apply an adequate amount of the 345 Barrier Cream as your final or semi-final step in your skincare routine.

What skin types is 345 Relief Cream good for?

Judged on how rich the formula reads from its ingredient list, it suits Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is 345 Relief Cream good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is 345 Relief Cream fungal acne safe?

No ingredient in this formula is a recognised food source for malassezia, the yeast behind fungal acne.

Can I use 345 Relief Cream while pregnant?

Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.

Is 345 Relief Cream fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does 345 Relief Cream contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is 345 Relief Cream silicone free?

No — it contains Vinyl Dimethicone, Caprylyl Methicone, Polymethylsilsesquioxane.

Does 345 Relief Cream contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is 345 Relief Cream paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with 345 Relief Cream?

It layers well with Vitamin C (L-ascorbic acid), Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide.

When should I apply 345 Relief Cream?

Use it morning and evening, after serums.

How many ingredients does 345 Relief Cream have?

It lists 38 ingredients, of which 5 are recorded as actives.

Who makes 345 Relief Cream?

Dr. Althea, a brand based in Korea.

Brand
Dr. Althea
Country
Korea

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