Centellian24 Madeca Cream Time Reverse

Centellian24

Madeca Cream Time Reverse

face neck cream

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Fit by skin type

General, ingredient-based — not your personalized match.

Dry
73%
Combination (dry)
73%
Balanced
97%
Combination (oily)
67%
Oily
67%

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105
Ingredients
8
Benefits
5
Actives
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The Centellian24 Madeca Cream Time Reverse is a rich, anti-aging moisturizer designed to improve the look of fine lines, enhance firmness, and support skin repair. Powered by Centellian24’s signature Madeca (Centella Asiatica-based) technology, it helps strengthen the skin barrier while delivering deep hydration and long-lasting comfort. Its nourishing texture melts into the skin to smooth roughness, boost elasticity, and leave the complexion looking healthier, plumper, and more radiant, ideal for daily use, especially for dry or aging skin.

Key Insights

Benefits

8
Anti-Acne
Anti-Aging
Dark Spot Fading
Evens Skin Tone
Hydration
Oil Control
Pore Minimizer
Soothing

Active Ingredients

5
Ceramides Hyaluronic acid Retinoids Vitamin B3 (niacinamide) Vitamin B5 (panthenol)

Risks

4
Allergen
Pregnancy Unsafe
Silicone
Synthetic polymer

Full Ingredients

105 total
WATER DIPROPYLENE GLYCOL HYDROGENATED POLYDECENE CAPRYLIC/CAPRIC TRIGLYCERIDE GLYCERIN GLYCERYL STEARATE PENTAERYTHRITYL TETRAETHYLHEXANOATE NIACINAMIDE Vitamin B3 (niacinamide) CYCLOHEXASILOXANE CETYL ALCOHOL POLYGLYCERYL-6 DISTEARATE VINYL DIMETHICONE DICAPRYLYL ETHER CENTELLA ASIATICA EXTRACT ASIATICOSIDE ASIATIC ACID MADECASSIC ACID CENTELLA ASIATICA OIL HYDROLYZED CENTELLA ASIATICA EXTRACT MADECASSOSIDE TRISODIUM ASCORBYL PALMITATE PHOSPHATE HYDROLYZED HYALURONIC ACID Hyaluronic acid CENTELLA ASIATICA LEAF EXTRACT CIMICIFUGA RACEMOSA ROOT EXTRACT SILYBUM MARIANUM EXTRACT LEPIDIUM MEYENII ROOT EXTRACT MACADAMIA TERNIFOLIA SEED OIL GLYCINE SOJA OIL HYDROGENATED LECITHIN SODIUM HYALURONATE Hyaluronic acid POLYGLYCERYL-10 LAURATE STEARYL ALCOHOL BEESWAX SODIUM STEAROYL GLUTAMATE PANTHENOL Vitamin B5 (panthenol) XYLITYLGLUCOSIDE HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER JOJOBA ESTERS ANHYDROXYLITOL BUTYLENE GLYCOL POLYGLYCERYL-3 BEESWAX 1,2-HEXANEDIOL HYDROXYACETOPHENONE XYLITOL METHYLPROPANEDIOL ALLANTOIN PROPANEDIOL CANDIDA BOMBICOLA/GLUCOSE/METHYL RAPESEEDATE FERMENT XANTHAN GUM ETHOXYDIGLYCOL DISODIUM EDTA GLUCOSE ADENOSINE SORBITAN ISOSTEARATE ETHYLHEXYLGLYCERIN SODIUM LAURATE CYCLODEXTRIN LAURIC ACID SODIUM POLYACRYLATE PVM/MA COPOLYMER OCTYLDODECANOL GLYCOLIPIDS CAFFEINE C12-13 PARETH-9 COLLAGEN AMINO ACIDS CERAMIDE NP Ceramides RESVERATROL ARGININE GLYCOGEN ECTOIN TAURINE HYDROLYZED ELASTIN RETINOL Retinoids MALTODEXTRIN PHYTOSPHINGOSINE SUCROSE DISTEARATE SODIUM DNA CYANOCOBALAMIN GLYCINE GLUTAMIC ACID HELIANTHUS ANNUUS SEED WAX POLYGLYCERIN-3 TOCOPHEROL ARTEMISIA ABSINTHIUM EXTRACT VANILLA PLANIFOLIA FRUIT EXTRACT OLEA EUROPAEA FRUIT OIL CITRUS AURANTIUM DULCIS OIL CITRUS NOBILIS PEEL OIL LAVANDULA ANGUSTIFOLIA OIL CITRUS AURANTIUM BERGAMIA FRUIT OIL ROSMARINUS OFFICINALIS LEAF OIL CITRUS AURANTIUM DULCIS PEEL OIL LITSEA CUBEBA FRUIT OIL JUNIPERUS VIRGINIANA OIL CITRUS GRANDIS PEEL OIL CEDRUS ATLANTICA BARK OIL PELARGONIUM GRAVEOLENS FLOWER OIL JASMINUM OFFICINALE FLOWER WATER MYRTUS COMMUNIS OIL ROSE FLOWER OIL FERULA GALBANIFLUA RESIN OIL COPAIFERA OFFICINALIS RESIN LIMONENE LINALOOL CITRAL

About Madeca Cream Time Reverse

Overview

Madeca Cream Time Reverse is a cushioning cream from Centellian24. The formula is built mainly around hydration and soothing. The ingredient list runs to 105 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as moderately cushioned — emollient enough to feel like a cream, without the heaviest occlusives near the top. It contains both silicones and oils, a combination that usually finishes smooth and slightly satin and sits well under makeup. Hydration is handled by Glycerin, Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: Very high. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate and Panthenol.

Soothing: High. Ingredients aimed at visible redness and reactivity, and here that comes from Pentaerythrityl Tetraethylhexanoate, Centella Asiatica Extract, Asiaticoside and Centella Asiatica Oil.

Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Madecassoside, Hydrogenated Lecithin and Panthenol.

Brightening: Moderate. Ingredients that act on uneven tone and post-inflammatory marks, and here that comes from Niacinamide, Trisodium Ascorbyl Palmitate Phosphate, Silybum Marianum Extract and Resveratrol.

Who it suits

On richness alone it suits Balanced skin best, and is the least natural fit for Dry, Combination (dry), Combination (oily) and Oily skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on cell renewal and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is no drying alcohol, paraben-free, microplastic-free, sulfate-free and dye-free. Those claims come from the ingredient list itself, not from the packaging. It does contain fragrance and essential oils, worth knowing if your skin reacts to any of them.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after serums. Seal in your serums with it; in the morning, sunscreen still goes on top.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No drying alcohol
  • No microplastics
  • Strong humectant content for hydration
  • Several soothing ingredients
  • No common irritants flagged in the list

Things to know

  • Contains fragrance or declared fragrance allergens
  • Contains essential oils, a common source of reactivity
  • 14 ingredients could feed malassezia (fungal acne)
  • Contains ingredients usually flagged for review during pregnancy

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin

Less suitable for

  • Dry skin
  • Combination (dry) skin
  • Combination (oily) skin
  • Oily skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 40 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 24 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 16 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Dark Spot Fading 2 ingredients

    Fades hyperpigmentation and evens out dark spots over time

  • Evens Skin Tone 2 ingredients

    Brightens and balances complexion for a more uniform appearance

  • Oil Control 2 ingredients

    Regulates sebum production to reduce shine and greasiness

  • Pore Minimizer 2 ingredients

    Tightens and refines the look of enlarged pores

  • Anti-Acne 1 ingredient

    Targets breakouts by reducing bacteria and unclogging pores

Does not target

Blackhead Reducing Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

3rd on the list, which puts it at an estimated 5–20% of the formula.

1-Decene, homopolymer, hydrogenated

Hydration

4th on the list, which puts it at an estimated 2–10% of the formula.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration

5th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

6th on the list, which puts it at an estimated 2–10% of the formula.

Stearic acid, monoester with glycerol

Hydration

7th on the list, which puts it at an estimated 1–5% of the formula.

2,2-bis[[(2-Ethyl-1-oxohexyl)oxy]methyl]propane-1,3-diyl bis(2-ethylhexanoate)

Hydration
Niacinamide Vitamin B3 (niacinamide)

8th on the list, which puts it at an estimated 1–5% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

9th on the list, which puts it at an estimated 1–5% of the formula.

Dodecamethylcyclohexasiloxane

Hydration

10th on the list, which puts it at an estimated 1–5% of the formula.

Hexadecan-1-ol

Hydration

11th on the list, which puts it at an estimated 1–3% of the formula.

diester of hexaglycerol and stearic acid

Hydration

13th on the list, which puts it at an estimated 1–3% of the formula.

Dioctyl ether

Hydration

14th on the list, which puts it at an estimated 1–3% of the formula.

Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae

Soothing Anti-Aging

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration Very high

Ingredients that pull and hold water in the upper layers of skin

Barrier support Moderate

Lipids and repair signals that support skin barrier integrity

Antioxidant support Low

Ingredients that mop up free radicals from UV and pollution

Oil control Low

Ingredients that moderate sebum or absorb shine

Brightening Moderate

Ingredients that act on uneven tone and post-inflammatory marks

Soothing High

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (6)

Supporting ingredients (99)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Dipropylene Glycol Hydrogenated Polydecene Caprylic/capric Triglyceride Glycerin Glyceryl Stearate Pentaerythrityl Tetraethylhexanoate Cyclohexasiloxane Cetyl Alcohol Polyglyceryl-6 Distearate Vinyl Dimethicone Dicaprylyl Ether Centella Asiatica Extract Asiaticoside Asiatic Acid Madecassic Acid Centella Asiatica Oil Hydrolyzed Centella Asiatica Extract Madecassoside Trisodium Ascorbyl Palmitate Phosphate Centella Asiatica Leaf Extract Cimicifuga Racemosa Root Extract Silybum Marianum Extract Lepidium Meyenii Root Extract Macadamia Ternifolia Seed Oil Glycine Soja Oil Hydrogenated Lecithin Polyglyceryl-10 Laurate Stearyl Alcohol Beeswax Sodium Stearoyl Glutamate Xylitylglucoside Hydroxyethyl Acrylate/sodium Acryloyldimethyl Taurate Copolymer Jojoba Esters Anhydroxylitol Butylene Glycol Polyglyceryl-3 Beeswax 1,2-hexanediol Hydroxyacetophenone Xylitol Methylpropanediol Allantoin Propanediol Candida Bombicola/glucose/methyl Rapeseedate Ferment Xanthan Gum Ethoxydiglycol Disodium Edta Glucose Adenosine Sorbitan Isostearate Ethylhexylglycerin Sodium Laurate Cyclodextrin Lauric Acid Sodium Polyacrylate Pvm/ma Copolymer Octyldodecanol Glycolipids Caffeine C12-13 Pareth-9 Collagen Amino Acids Resveratrol Arginine Glycogen Ectoin Taurine Hydrolyzed Elastin Maltodextrin Phytosphingosine Sucrose Distearate Sodium DNA Cyanocobalamin Glycine Glutamic Acid Helianthus Annuus Seed Wax Polyglycerin-3 Tocopherol Artemisia Absinthium Extract Vanilla Planifolia Fruit Extract Olea Europaea Fruit Oil Citrus Aurantium Dulcis Oil Citrus Nobilis Peel Oil Lavandula Angustifolia Oil Citrus Aurantium Bergamia Fruit Oil Rosmarinus Officinalis Leaf Oil Citrus Aurantium Dulcis Peel Oil Litsea Cubeba Fruit Oil Juniperus Virginiana Oil Citrus Grandis Peel Oil Cedrus Atlantica Bark Oil Pelargonium Graveolens Flower Oil Jasminum Officinale Flower Water Myrtus Communis Oil Rose Flower Oil Ferula Galbaniflua Resin Oil Copaifera Officinalis Resin Limonene Linalool Citral

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • No drying alcohol
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free

Contains

  • Fragrance

    Limonene, Linalool, Citral

  • Essential oils

    Lavandula Angustifolia Oil, Rosmarinus Officinalis Leaf Oil, Citrus Aurantium Dulcis Peel Oil, Litsea Cubeba Fruit Oil, Juniperus Virginiana Oil

  • Silicones

    Cyclohexasiloxane, Vinyl Dimethicone

  • Facial oils

    Macadamia Ternifolia Seed Oil, Olea Europaea Fruit Oil, Citrus Aurantium Bergamia Fruit Oil, Litsea Cubeba Fruit Oil

  • Animal-derived ingredients

    Beeswax

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Retinoids (retinol, retinal)
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • AHAs (glycolic, lactic)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • BHA (salicylic acid)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • PHAs (gluconolactone)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Benzoyl peroxide

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Vitamin C (L-ascorbic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • Azelaic acid

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Moisturise" step.

  • Seal in your serums with it; in the morning, sunscreen still goes on top.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Contains Retinol, usually reviewed with a doctor during pregnancy.
Fungal acne (malassezia)
14 ingredients could feed malassezia: Glyceryl Stearate, Polyglyceryl-6 Distearate, Trisodium Ascorbyl Palmitate Phosphate, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Laurate, Sorbitan Isostearate, Sodium Laurate, Sucrose Distearate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Allergen, Pregnancy Unsafe, Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 105 ingredients on the label.

17
Humectant

Draws water into the upper layers of skin

15
Emollient

Softens and smooths by filling gaps between skin cells

15
Surfactant

Lifts oil and dirt, or holds oil and water together

15
Texture agent

Sets the thickness, spread and stability of the formula

13
Solvent

Dissolves and carries everything else

11
Occlusive

Forms a film that slows water loss

9
Antioxidant

Neutralises free radicals from UV and pollution

9
Plant extract

Botanical material, usually for antioxidants or scent

6
Active

Changes how skin behaves rather than how it feels

4
Preservative

Keeps the product free of microbial growth

3
Fragrance / colour

Changes how the product smells or looks

3
Soothing

Calms visible redness and irritation

2
Chelator

Binds trace metals that would otherwise spoil the formula

2
pH adjuster

Sets the acidity the formula needs to work

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Dipropylene Glycol Texture agent
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol

Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

1-Decene, homopolymer, hydrogenated

Hydration
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line

4th on the list, which puts it at an estimated 2–10% of the formula.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration
5 scientific references
  • International Journal of Toxicology, September 2020, pages 34-35
  • Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
  • International Journal of Toxicology, January 2003, pages 4-5
  • Food and Chemical Toxicology, January 2000, pages 79-98
  • Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
5 Glycerin Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

5th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Surfactant

6th on the list, which puts it at an estimated 2–10% of the formula.

Stearic acid, monoester with glycerol

Hydration
3 scientific references
  • Cosmeticsinfoorg, Accessed November 2021, ePublication
  • Drugs in Context, April 2018, pages 1-14
  • International Journal of Toxicology, May 2007, pages 1–30
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Texture agent

7th on the list, which puts it at an estimated 1–5% of the formula.

2,2-bis[[(2-Ethyl-1-oxohexyl)oxy]methyl]propane-1,3-diyl bis(2-ethylhexanoate)

Hydration
8 Niacinamide Active
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

8th on the list, which puts it at an estimated 1–5% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Solvent

9th on the list, which puts it at an estimated 1–5% of the formula.

Dodecamethylcyclohexasiloxane

Hydration
2 scientific references
  • Dow (supplier info), Accessed September 2021, ePublication
  • International Journal of Toxicology, December 2011, pages 149S-227S
10 Cetyl Alcohol Emollient
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Surfactant, Texture agent

10th on the list, which puts it at an estimated 1–5% of the formula.

Hexadecan-1-ol

Hydration
3 scientific references
  • International Journal of Cosmetic Science, December 2012, Issue 34, Volume 6, pages 567-74
  • http://wwwcir-safetyorg/sites/default/files/115_buff3a_supplpdf
  • https://pubchemncbinlmnihgov/compound/1-Hexadecanol
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

11th on the list, which puts it at an estimated 1–3% of the formula.

diester of hexaglycerol and stearic acid

Hydration
3 scientific references
  • Cosmetics, October 2018, pages 1–11
  • International Journal of Pharmaceutics, March 2011, pages 163–172
  • https://wwwcir-safetyorg/sites/default/files/PGlyFE092016FRpdf
12 Vinyl Dimethicone Texture agent
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent

12th on the list, which puts it at an estimated 1–3% of the formula.

Silicones and siloxanes, dimethyl, ethenyl methyl, ethenyldimethylsilyl terminated

Silicone
13 Dicaprylyl Ether Emollient
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Solvent

13th on the list, which puts it at an estimated 1–3% of the formula.

Dioctyl ether

Hydration
2 scientific references
  • SpecialChem, Accessed January 2022, ePublication
  • Personal Care Council, December 2021, ePublication
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Soothing, Surfactant, Plant extract

14th on the list, which puts it at an estimated 1–3% of the formula.

Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae

Soothing Anti-Aging
6 scientific references
  • Phytomedicine, April 2018, pages 110–119
  • Clinical, Cosmetic, and Investigational Dermatology, August 2017, pages 311–315
  • Indian Journal of Pharmaceutical Sciences, Jan-Feb 2016, pages 27–33
  • Postepy Dermatologii I, February 2013, pages 46–49
  • Indian Journal of Pharmaceutical Sciences, 2010, pages 546–556
  • Scientific Reports, June 2021, ePublication
15 Asiaticoside Antioxidant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Antioxidant

15th on the list, which puts it at an estimated 1–3% of the formula.

Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester (2alpha, 3beta, 4alpha)-

Anti-Aging Soothing
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line

16th on the list, which puts it at an estimated 1–3% of the formula.

(2.alpha.,3.beta.,4.alpha.)-2,3,23-Trihydroxyurs-12-en-28-oic acid

Anti-Aging
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line

17th on the list, which puts it at an estimated 1–3% of the formula.

Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-

Anti-Aging Soothing
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Antioxidant, Preservative

18th on the list, which puts it at an estimated 1–3% of the formula.

Centella Asiatica Oil is the volatile oil obtained from the whole plant Centella asiatica, Apiaceae.

Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Antioxidant, Plant extract

19th on the list, which puts it at an estimated 1–3% of the formula.

Hydrolyzed Centella Asiatica Extract

20 Madecassoside Antioxidant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Antioxidant

20th on the list, which puts it at an estimated 1–3% of the formula.

O-6-Deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oate

Anti-Aging Soothing
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Antioxidant

21st on the list, which puts it at an estimated 1–3% of the formula.

Trisodium Ascorbyl Palmitate Phosphate

Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Active

22nd on the list, which puts it at an estimated 1–3% of the formula.

Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis

Hydration
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Plant extract

23rd on the list, which puts it at an estimated 1–3% of the formula.

Centella Asiatica Leaf Extract is an extract of the leaves of the Hydrocotyl, Centella asiatica L., Apiaceae

Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Emollient, Occlusive, Antioxidant, Plant extract, Preservative

24th on the list, which puts it at an estimated 1–3% of the formula.

Cimicifuga Racemosa Root Extract is an extract of the roots of the Black Cohosh, Cimicifuga racemosa, Ranunculaceae

Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Plant extract

25th on the list, which puts it at an estimated 1–3% of the formula.

Silybum Marianum Extract is an extract of the seeds and leaves of the Lady's Thistle, Silybum marianum (L.), Asteraceae

Anti-Aging Dark Spot Fading Soothing
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Plant extract

26th on the list, which puts it at an estimated 1–3% of the formula.

Lepidium Meyenii Root Extract is an extract of the roots of the Lepidium meyenii, Brassicaceae

Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

27th on the list, which puts it at an estimated 1–3% of the formula.

Macadamia Ternifolia Seed Oil is the fixed oil obtained from the nuts of the Bushnut, Macadamia ternifolia, Proteaceae. It consists primarily of the glycerides of the fatty acids

28 Glycine Soja Oil Emollient
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

28th on the list, which puts it at an estimated 1–3% of the formula.

Glycine Soja Oil is the oil obtained from the soybean, Glycine soja, Leguminosae, by extraction or expression. It consists esentially of triglycerides of oleic, linoleic and saturated acids

Anti-Aging Hydration
8 scientific references
  • Phytotherapy Research, March 2020, pages 435-437
  • AAPS PharmSciTech, October 2018, pages 3, 029-3, 039
  • The Journal of Clinical and Aesthetic Dermatology, February 2018, pages 28-37
  • International Journal of Molecular Sciences, December 2017, ePublication
  • Molecules, Volume 22, September 2017, ePublication
  • Journal of Drugs in Dermatology, September 2013, pages s123-s127
  • Journal of Medicinal Food, January 2012, pages 89-95
  • International Journal of Dermatology, April 2011, pages 470-477
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

29th on the list, which puts it at an estimated 1–3% of the formula.

Lecithins, hydrogenated

Hydration
4 scientific references
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Nanocosmetics, June 2019, pages 95–140
  • Current Drug Delivery, 2016, pages 111–120
  • Pharmaceutical Research, February 2013, pages 538–55
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Active

30th on the list, which puts it at an estimated 1–3% of the formula.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line

31st on the list, which puts it at an estimated 1–3% of the formula.

1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio)

32 Stearyl Alcohol Emollient
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Surfactant, Texture agent

32nd on the list, which puts it at an estimated 1–3% of the formula.

Octadecan-1-ol

33 Beeswax Texture agent
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent

33rd on the list, which puts it at an estimated 1–3% of the formula.

Beeswax absolute (RIFM),Beeswax concrete (RIFM),Beeswax, white (Apis mellifera L.) (RIFM),Bleached Beeswax,Cera Alba (EU),White Beeswax,White Wax,Yellow Wax

Hydration
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

34th on the list, which puts it at an estimated 1–3% of the formula.

Sodium hydrogen N-(1-oxooctadecyl)-L-glutamate

Hydration
35 Panthenol Active
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

35th on the list, which puts it at an estimated 1–3% of the formula.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
36 Xylitylglucoside Humectant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant

36th on the list, which puts it at an estimated 1–3% of the formula.

Xylitylglucoside

Hydration Soothing
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent

37th on the list, which puts it at an estimated 1–3% of the formula.

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium hydroxyethyl acrylate and acryloyldimethyl taurate monomers

Synthetic polymer
38 Jojoba Esters Humectant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Emollient, Soothing

38th on the list, which puts it at an estimated 1–3% of the formula.

Jojoba Esters is a complex mixture of esters produced by the transesterification/interesterification of Simmondsia Chinensis (Jojoba) Oil (q.v.), Hydrogenated Jojoba Oil (q.v.), or a mixture of the two

Hydration
39 Anhydroxylitol Humectant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant

39th on the list, which puts it at an estimated 1–3% of the formula.

D-Xylitol, 1,4-Anhydro-

Hydration
40 Butylene Glycol Humectant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

40th on the list, which puts it at an estimated 1–3% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

41st on the list, which puts it at an estimated 1–3% of the formula.

Ester of triglycerol and beeswax fatty acids

42 1,2-hexanediol Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

43 Hydroxyacetophenone Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone

Anti-Aging Hydration
4 scientific references
  • Journal of Oleo Science, February 2019, pages 183-191
  • Applied Environmental Microbiology, June 2018, ePublication
  • Journal of Biosciences, May-June 2004, pages 345-353
  • Scientific Reports, April 2021, pages 1–7
44 Xylitol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Xylitol

Hydration Soothing
7 scientific references
  • Microorganisms, January 2021, pages 1–14
  • Clinical, Cosmetic, and Investigational Dermatology, May 2019, pages 323-331
  • Advances in Nutrition, January 2019, Supplement, pages S31-S48
  • Experimental Dermatology, March 2018, pages 280-284
  • International journal of Applied Pharmaceutical and Biological Research, 2017, pages 67-73
  • Acta-dermato venereological, February 2017, pages 182-187
  • https://wwwcir-safetyorg/sites/default/files/Mannitol, %20Sorbitol, %20Xylitol_0pdf
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Methyl-1,3-propanediol

Hydration
3 scientific references
  • PubChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Contact Dermatitis, September 2017, pages 159-162
46 Allantoin Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Soothing

46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urea, (2,5-dioxo-4-imidazolidinyl)-

Soothing
8 scientific references
  • Chemistry Series, March 2020, pages 7-21
  • Molecules, June 2019, pages 1-33
  • European Journal of Pharmacology, February 2018, pages 68-78
  • Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
  • Pharmacognosy Review, Volume 5, July-December 2011
  • International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
  • Journal of Occupational Medicine and Toxicology, October 2008, ePublication
  • https://wwwaccessdatafdagov/scripts/cdrh/cfdocs/cfcfr/CFRSearchcfm?CFRPart=347&showFR=1
47 Propanediol Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Solvent

47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-dihydroxypropane

Hydration
4 scientific references
  • PubChem Compound Summary, April 2021, ePublication
  • SpecialChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Cosmetics & Toiletries, May 2013, pages 81-86
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Surfactant, Preservative

48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Product obtained by the fermentation of glucose and methyl rapeseedate by the microorganism Candida bombicola

49 Xanthan Gum Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant, Texture agent

49th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Xanthan gum

50 Ethoxydiglycol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Solvent

50th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-(2-Ethoxyethoxy)ethanol; Carbitol; Diethylene glycol monoethyl ether; DEGEE

51 Disodium Edta Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Chelator

51st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Disodium dihydrogen ethylenediaminetetraacetate

52 Glucose Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

52nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glucose

Hydration
4 scientific references
  • International Journal of Molecular Sciences, March 2020, pages 1–13
  • Foods, March 2019, pages 1–27
  • Nature Medicine, May 2018, pages 617–627
  • Clinical Chemistry and Laboratory Medicine, September 2003, pages 1, 224–1, 228
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

53rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

54th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sorbitan, isooctadecanoate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

55th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
56 Sodium Laurate Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

56th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dodecanoic Acid, Sodium Salt

57 Cyclodextrin Chelator
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Chelator

57th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cycloheptapentylose

58 Lauric Acid Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

58th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dodecanoic acid

Hydration Soothing
5 scientific references
  • Dermatologic Therapy, July 2020, pages 1-4
  • IOP Conference Series: Earth and Environmental Science, June 2020, pages 1-6
  • Biomaterials, October 2009, pages 6, 035-6, 040
  • Journal of the American college of Toxicology, 1987, pages 1-81
  • Tenside Surfactants Detergents, December 1976, pages 313-316
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Occlusive, Texture agent

59th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, homopolymer, sodium salt

Oil Control Synthetic polymer
7 scientific references
  • International Food Research Journal, February 2021, pages 44 - 55
  • Journal of Nanoscience and Nanotechnology, March 2018, pages 1, 611-1, 614
  • Industrial & Engineering Chemistry Research, November 2014, pages 18, 346-18, 351
  • Journal of Applied Polymer Science, November 2001, pages 1, 515-1, 520
  • United States Patent, April 2000, ePublication
  • https://wwwsocochemcom/is-sodium-polyacrylate-safehtml
  • https://wwwcir-safetyorg/sites/default/files/acryco092018TARpdf
60 Pvm/ma Copolymer Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

60th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,5-Furandione, polymer with methoxyethene; copolymer of methyl vinyl ether and maleic anhydride

61 Octyldodecanol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Solvent

61st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Octyldodecan-1-ol

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

62nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycolipids are mixed substances which contain carbohydrates covalently attached to a lipid

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

63rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-

Anti-Aging
64 C12-13 Pareth-9 Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

64th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Alcohols, C12-13, ethoxylated (9 mol EO average molar ratio)

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

65th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Amino Acids derived from collagen

Hydration
66 Ceramide NP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

66th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Hydration Anti-Aging
11 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
67 Resveratrol Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Antioxidant

67th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Benzenediol, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-

Anti-Aging Dark Spot Fading Soothing
8 scientific references
  • Biomedicine and Pharmacotherapy, November 2021, ePublication
  • International Journal of Molecular Sciences, October 2021, pages 1–26
  • Phytotherapy Research, March 2020, pages 435–447
  • Biomolecules and Therapeutics, October 2018, pages 1–14
  • Journal of Cosmetic and Laser Therapy, May 2018 ePublication
  • Journal of Drugs in Dermatology, December 2013, pages 1389-1394
  • Archives of Biochemistry and Biophysics, April 2011, pages 164-170
  • Antioxidants and Redox Signaling, December 2001, pages 1041-1064
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

68th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

L-Arginine

Hydration Anti-Aging
6 scientific references
  • Biobased Surfactants (Second Edition), 2019, pages 413-445
  • Scientific Reports, February 2016, pages 1-10
  • Cosmetic Ingredient Review, October 2012, pages 1-35
  • Journal of Advanced Research, July 2010, pages 169–177
  • International Journal of Cosmetic Science, April 2005, page 139
  • Wound Repair and Regeneration, November-December 2003, pages 419-423
69 Glycogen Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

69th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycogen

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

70th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

4-Pyrimidinecarboxylic Acid, 1,4,5,6,-Tetrahydro-2-Methyl-, (4S)-

Hydration Anti-Aging Evens Skin Tone
71 Taurine pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

71st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ethanesulfonic acid, 2-amino-

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

72nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydrolyzed Elastin is the hydrolysate of elastin derived by acid, enzyme or other method of hydrolysis

Hydration
73 Retinol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

73rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Retinol; vitamin A

Anti-Aging Anti-Acne Pore Minimizer Pregnancy Unsafe
10 scientific references
  • Journal of Drugs in Dermatology, September 2019, pages 918-923; and March 2015, pages 271-280
  • Experimental Dermatology, August 2019, pages 906-913
  • Archives of Dermatological Research, May 2017, pages 275-283
  • International Journal of Cosmetic Science, February 2017, pages 56-65
  • Dermatology, May 2014, pages 314-325
  • Dermatoendocrinology, July 2012, issue 3, pages 308-319
  • Toxicological Research, March 2010, pages 61-66
  • Archives of Dermatology, May 2007, pages 606-612
  • The Journal of Pathology, January 2007, issue 2, pages 241-251
  • Clinical Interventions in Aging, December 2006, pages 327-348
74 Maltodextrin Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

74th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Maltodextrin

Oil Control Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

75th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3,4-Octadecanetriol, 2-amino-, (2S, 3S, 4R)-

Anti-Aging Hydration
6 scientific references
  • Journal of Dermatological Science, January 2020, Volume 97, Issue 1, pages 2-8
  • Archives of Dermatological Research, December 2017, Volume 309, Issue 10, pages 795-803
  • Biochimica et Biophysica Acta: Biomembranes, May 2017, Volume 1859, Issue 5, pages 824-834
  • International Journal of Cosmetic Science, June 2007, Volume 29, Issue 3, pages 181-190
  • Molecular Medicine, January-March 2006, pages 17-24
  • Journal of Investigative Dermatology, October 2003, issue 5, pages 1135–1137
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

76th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sucrose distearate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

77th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Deoxyribonucleic acid, sodium salts

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

78th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cyanocobalamin; Vitamine B12

Anti-Aging
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
79 Glycine pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

79th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycine

Hydration
4 scientific references
  • Amino Acids in Nutrition and Health, August 2020, pages 187-199
  • Current Medicinal Chemistry, 2018, pages 5, 512-5, 527, ePublication
  • PLoS ONE, February 2018, ePublication
  • International Journal of Cosmetic Science, October 2009, pages 327-345
80 Glutamic Acid Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

80th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

(S)-2-Aminopentanedioic acid

Hydration
4 scientific references
  • Malaysian Applied Biology, May 2018, pages 113–117
  • Saudi Journal of Biological Sciences, April 2014, pages 153-158
  • International Journal of Toxicology, 2013, pages 41S-64S
  • Journal of Investigative Dermatology, June 2003, pages 1, 023-1, 029
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

81st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Helianthus Annus Seed Wax

82 Polyglycerin-3 Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

82nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Triglycerol

83 Tocopherol Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

83rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E

Anti-Aging Evens Skin Tone Soothing
4 scientific references
  • Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
  • Journal of Investigative Dermatology, November 2001, pages 1212-1217
  • Canadian Family Physician, July 2006, pages 855-856
  • Dermatologic Surgery, April 1999, pages 311-315
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

84th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Artemisia Absinthium Extract is an extract of the whole herb of the Wormwort, Artemisia absinthium L., Compositae

Anti-Aging
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Plant extract

85th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Vanilla Planifolia Fruit Extract is an extract of the fruit of the Vanilla, Vanilla planifolia, Orchidaceae

Anti-Aging Soothing
7 scientific references
  • Pharmacological Research, March 2019, pages 208-213
  • British Journal of Dermatology, February 2019, pages 253-254
  • Oncotarget, March 2016, pages 14, 616-14, 627
  • International Journal of Cosmetic Science, June 2014, issue 3, pages 221-230
  • Bioscience, Biotechnology, and Biochemistry, Volume 74, Issue 7, 2010, pages 1504-1506
  • The American Journal of Chinese Medicine, 2010, pages 105-114
  • Pharmacognosy Review, January-June 2010, pages 68-76
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

86th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Olea Europaea Fruit Oil is the fixed oil obtained from the ripe fruit of the Olive, Olea europaea L., Oleaceae. It consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic

Hydration Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

87th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Citrus Aurantium Dulcis Oil is the volatile oil obtained from the whole plant, Citrus aurantium dulcis

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

88th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Citrus Nobilis Peel Oil is the oil expressed from the peel of the Mandarin, Citrus nobilis, Rutaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

89th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lavandula Angustifolia Oil is the volatile oil obtained from the flowers of the Lavender, Lavandula angustifolia, Labiatae. ISO 8902:2009

Allergen
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

90th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Citrus Aurantium Bergamia Fruit Oil is the psoralen-free volatile oil obtained from the fruit of Citrus aurantium L. var. bergamia, Rutaceae; Oils, bergamot; bergamot oil bergaptene free

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

91st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Rosmarinus Officinalis Leaf Oil is the essential oil obtained from the flowering tops and leaves of the Rosemary, Rosmarinus officinalis L., Lamiaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

92nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Citrus Sinensis Oil,Orange Oil,Orange oil terpeneless (Citrus sinensis (L.) Osbeck) (RIFM),Orange peel oil, sweet (Citrus sinensis (L.) Osbeck) (RIFM),Orange Yu (JPN)

Allergen
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

93rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Litsea Cubeba Fruit Oil is the volatile oil obtained from the berries of the Litsea cubeba, Lauraceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

94th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Juniperus Virginiana Oil is the volatile oil obtained from the fruits and leaves of the Red Cedar, Juniperus virginiana L., Cupressaceae

Allergen
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

95th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Citrus Grandis Peel Oil is the volatile oil obtained from the peel of the Grapefruit, Citrus grandis, Rutaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

96th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cedrus Atlantica Bark Oil is the volatile oil obtained from the bark of Cedrus atlantica, Pinaceae

Allergen
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

97th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Pelargonium Graveolens Flower Oil is the volatile oil obtained from the flowers of the Bourbon Geranium, Pelargonium graveolens (L.), Geraniaceae

Allergen
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

98th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Jasminum Officinale Flower Water is an aqueous solution of the steam distillate obtained from the flowers of the Jasmine, Jasminum officinale L., Oleaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

99th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Myrtus Communis Oil is a volatile oil obtained from the leaves of the Myrtle, Myrtus communis L., Myrtaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

100th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Rose Flower Oil is the volatile oil obtained from the flowers of Rosa spp. , rosaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Preservative

101st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Galbanum Oil. Ferula Galbaniflua Resin Oil is the essential oil obtained from the resin of the Galbanum, Ferula galbaniflua, Apiaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

102nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Copaifera Officinalis Resin is an oleoresin (Balsam Copaiba) obtained from the Copaiba, Copaifera officinalis L., Leguminosae. It consists primarily of resins, essential oils, and usually cinnamic and benzoic acids

103 Limonene Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent, Fragrance / colour

103rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1-Methyl-4-Isopropenylcyclohexene; dipentene

Allergen
104 Linalool Fragrance / colour
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Fragrance / colour

104th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,7-Dimethyl octa-1,6-diene-3-ol

Allergen
105 Citral Fragrance / colour
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Fragrance / colour

105th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,6-Octadienal, 3,7-dimethyl-; 3,7-Dimethyl-2,6-octadienal

Allergen

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Frequently asked questions

What ingredients are in Madeca Cream Time Reverse?

WATER, DIPROPYLENE GLYCOL, HYDROGENATED POLYDECENE, CAPRYLIC/CAPRIC TRIGLYCERIDE, GLYCERIN, GLYCERYL STEARATE, PENTAERYTHRITYL TETRAETHYLHEXANOATE, NIACINAMIDE, CYCLOHEXASILOXANE, CETYL ALCOHOL, POLYGLYCERYL-6 DISTEARATE, VINYL DIMETHICONE, DICAPRYLYL ETHER, CENTELLA ASIATICA EXTRACT, ASIATICOSIDE, ASIATIC ACID, MADECASSIC ACID, CENTELLA ASIATICA OIL, HYDROLYZED CENTELLA ASIATICA EXTRACT, MADECASSOSIDE, TRISODIUM ASCORBYL PALMITATE PHOSPHATE, HYDROLYZED HYALURONIC ACID, CENTELLA ASIATICA LEAF EXTRACT, CIMICIFUGA RACEMOSA ROOT EXTRACT, SILYBUM MARIANUM EXTRACT, LEPIDIUM MEYENII ROOT EXTRACT, MACADAMIA TERNIFOLIA SEED OIL, GLYCINE SOJA OIL, HYDROGENATED LECITHIN, SODIUM HYALURONATE, POLYGLYCERYL-10 LAURATE, STEARYL ALCOHOL, BEESWAX, SODIUM STEAROYL GLUTAMATE, PANTHENOL, XYLITYLGLUCOSIDE, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, JOJOBA ESTERS, ANHYDROXYLITOL, BUTYLENE GLYCOL, POLYGLYCERYL-3 BEESWAX, 1,2-HEXANEDIOL, HYDROXYACETOPHENONE, XYLITOL, METHYLPROPANEDIOL, ALLANTOIN, PROPANEDIOL, CANDIDA BOMBICOLA/GLUCOSE/METHYL RAPESEEDATE FERMENT, XANTHAN GUM, ETHOXYDIGLYCOL, DISODIUM EDTA, GLUCOSE, ADENOSINE, SORBITAN ISOSTEARATE, ETHYLHEXYLGLYCERIN, SODIUM LAURATE, CYCLODEXTRIN, LAURIC ACID, SODIUM POLYACRYLATE, PVM/MA COPOLYMER, OCTYLDODECANOL, GLYCOLIPIDS, CAFFEINE, C12-13 PARETH-9, COLLAGEN AMINO ACIDS, CERAMIDE NP, RESVERATROL, ARGININE, GLYCOGEN, ECTOIN, TAURINE, HYDROLYZED ELASTIN, RETINOL, MALTODEXTRIN, PHYTOSPHINGOSINE, SUCROSE DISTEARATE, SODIUM DNA, CYANOCOBALAMIN, GLYCINE, GLUTAMIC ACID, HELIANTHUS ANNUUS SEED WAX, POLYGLYCERIN-3, TOCOPHEROL, ARTEMISIA ABSINTHIUM EXTRACT, VANILLA PLANIFOLIA FRUIT EXTRACT, OLEA EUROPAEA FRUIT OIL, CITRUS AURANTIUM DULCIS OIL, CITRUS NOBILIS PEEL OIL, LAVANDULA ANGUSTIFOLIA OIL, CITRUS AURANTIUM BERGAMIA FRUIT OIL, ROSMARINUS OFFICINALIS LEAF OIL, CITRUS AURANTIUM DULCIS PEEL OIL, LITSEA CUBEBA FRUIT OIL, JUNIPERUS VIRGINIANA OIL, CITRUS GRANDIS PEEL OIL, CEDRUS ATLANTICA BARK OIL, PELARGONIUM GRAVEOLENS FLOWER OIL, JASMINUM OFFICINALE FLOWER WATER, MYRTUS COMMUNIS OIL, ROSE FLOWER OIL, FERULA GALBANIFLUA RESIN OIL, COPAIFERA OFFICINALIS RESIN, LIMONENE, LINALOOL, CITRAL.

What are the active ingredients in Madeca Cream Time Reverse?

NIACINAMIDE, HYDROLYZED HYALURONIC ACID, SODIUM HYALURONATE, PANTHENOL, CERAMIDE NP, RETINOL.

How do I use Madeca Cream Time Reverse?

At the final step of your skincare routine, take an appropriate amount and gently massage it into your face and neck. Use morning and/or evening as needed. Tip: Apply it when your skin is slightly damp (after toner or essence) to help lock in moisture more effectively. Start with a thin layer, and increase slightly in colder or drier weather for added protection.

What skin types is Madeca Cream Time Reverse good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry), Combination (oily), Oily skin.

Is Madeca Cream Time Reverse good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is Madeca Cream Time Reverse fungal acne safe?

14 ingredients could feed malassezia: Glyceryl Stearate, Polyglyceryl-6 Distearate, Trisodium Ascorbyl Palmitate Phosphate, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Laurate, Sorbitan Isostearate, Sodium Laurate, Sucrose Distearate. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use Madeca Cream Time Reverse while pregnant?

It contains Retinol, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.

Is Madeca Cream Time Reverse fragrance free?

No — it contains Limonene, Linalool, Citral.

Does Madeca Cream Time Reverse contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is Madeca Cream Time Reverse silicone free?

No — it contains Cyclohexasiloxane, Vinyl Dimethicone.

Does Madeca Cream Time Reverse contain essential oils?

Yes — it contains Lavandula Angustifolia Oil, Rosmarinus Officinalis Leaf Oil, Citrus Aurantium Dulcis Peel Oil, Litsea Cubeba Fruit Oil, Juniperus Virginiana Oil.

Is Madeca Cream Time Reverse paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with Madeca Cream Time Reverse?

It layers well with Retinoids (retinol, retinal), Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides. Take more care combining it with AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide, Vitamin C (L-ascorbic acid), Azelaic acid — use them in separate routines or on alternate days.

When should I apply Madeca Cream Time Reverse?

Use it morning and evening, after serums.

How many ingredients does Madeca Cream Time Reverse have?

It lists 105 ingredients, of which 6 are recorded as actives.

Who makes Madeca Cream Time Reverse?

Centellian24.

Brand
Centellian24

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