md:ceuticals melan:off maintenance cream

md:ceuticals

melan:off maintenance cream

face neck body hands cream

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Fit by skin type

General, ingredient-based — not your personalized match.

Dry
67%
Combination (dry)
67%
Balanced
97%
Combination (oily)
73%
Oily
73%

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43
Ingredients
9
Benefits
3
Actives
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Whitening cream for topical use for a perfect skin. It produces effective skin whitening, eliminating blemishes of melanic origin, accelerating cell renewal, increasing skin luminosity, and protecting against solar radiations.

Key Insights

Benefits

9
Anti-Acne
Anti-Aging
Dark Spot Fading
Evens Skin Tone
Hydration
Oil Control
Pore Minimizer
Smooths Bumpy Skin
Soothing

Active Ingredients

3
Retinoids Vitamin B3 (niacinamide) Vitamin C

Risks

2
Pregnancy Unsafe
Silicone

About melan:off maintenance cream

Overview

melan:off maintenance cream is a cushioning cream from md:ceuticals. Its job is UV protection, with the rest of the formula working on hydration. The ingredient list runs to 43 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as moderately cushioned — emollient enough to feel like a cream, without the heaviest occlusives near the top. It contains both silicones and oils, a combination that usually finishes smooth and slightly satin and sits well under makeup. Hydration is handled by Glycerin, Butylene Glycol and Water, humectants that pull water into the upper layers of skin rather than sealing it there.

UV filter system

It uses a hybrid filter system — Titanium Dioxide and Octinoxate — combining mineral and organic filters. Between them those filters cover UVB and UVA II. They stop short of UVA I (340–400 nm), the deepest ageing wavelengths, so this is not a broad-spectrum filter system by the strictest reading. One of the filters is photounstable and no recognised stabiliser sits beside it, so protection may drop measurably within the first hour of direct sun. Reapply more often than the label suggests.

What the formula does

Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Butylene Glycol, Water and Sorbitol.

Brightening: Moderate. Ingredients that act on uneven tone and post-inflammatory marks, and here that comes from Azelaic Acid, Niacinamide, Alpha-arbutin and Kojic Acid.

Cell renewal: Moderate. Retinoids, acids and enzymes that speed surface turnover, and here that comes from Retinyl Palmitate and Azelaic Acid.

Who it suits

On richness alone it suits Balanced skin best, and is the least natural fit for Dry, Combination (dry), Combination (oily) and Oily skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on barrier support, antioxidant protection and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after serums. Seal in your serums with it; in the morning, sunscreen still goes on top. It carries UV filters, so it belongs in your morning routine.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • A photounstable UV filter with no stabiliser beside it
  • Filter system does not reach UVA I
  • 4 ingredients could feed malassezia (fungal acne)
  • Contains ingredients usually flagged for review during pregnancy

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin

Less suitable for

  • Dry skin
  • Combination (dry) skin
  • Combination (oily) skin
  • Oily skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Anti-Aging 12 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Hydration 9 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Dark Spot Fading 5 ingredients

    Fades hyperpigmentation and evens out dark spots over time

  • Evens Skin Tone 4 ingredients

    Brightens and balances complexion for a more uniform appearance

  • Soothing 3 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Anti-Acne 1 ingredient

    Targets breakouts by reducing bacteria and unclogging pores

  • Oil Control 1 ingredient

    Regulates sebum production to reduce shine and greasiness

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

  • Smooths Bumpy Skin 1 ingredient

    Refines texture by gently exfoliating rough, uneven patches

Does not target

Blackhead Reducing

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

UV filters

Hybrid mineral and organic filter system · does not reach UVA I

Titanium Dioxide

titanium dioxide
Protects from
UVB (290–320 nm), UVA II (320–340 nm)
Photostable
Yes — photostable
Generation
Mineral (inorganic) filter
Approved in
Approved worldwide
Maximum permitted level
Up to 25% (EU, US, KR)

Strong UVB and short-UVA protection, but it stops before UVA I — a mineral formula leaning on titanium dioxide alone needs zinc oxide beside it for deep UVA.

Octinoxate

ethylhexyl methoxycinnamate
Protects from
UVB (290–320 nm)
Photostable
No — degrades in sunlight
Generation
First-generation UVB filter
Approved in
EU, UK, Korea, Japan, US — banned in Hawaii and Key West
Maximum permitted level
Up to 10% (EU), 7.5% (US)

Efficient UVB absorber that degrades in sunlight on its own, and destabilises avobenzone when the two are formulated together without a quencher.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

3rd on the list, which puts it at an estimated 5–20% of the formula.

Nonanedioic acid

Anti-Acne Dark Spot Fading Smooths Bumpy Skin

5th on the list, which puts it at an estimated 2–10% of the formula.

Titanium dioxide (CI 77891)

Anti-Aging

11th on the list, which puts it at an estimated 1–3% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

12th on the list, which puts it at an estimated 1–3% of the formula.

Silicic acid, aluminum magnesium salt

Oil Control
Niacinamide Vitamin B3 (niacinamide)

13th on the list, which puts it at an estimated 1–3% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

15th on the list, which puts it at an estimated 1–3% of the formula.

4-Hydroxyphenyl-alpha-D-glucopyranoside

Anti-Aging Dark Spot Fading Evens Skin Tone

17th on the list, which puts it at an estimated 1–3% of the formula.

D-Glucitol

Hydration

18th on the list, which puts it at an estimated 1–3% of the formula.

5-Hydroxy-2-hydroxymethyl-4-pyrone

Dark Spot Fading Evens Skin Tone Anti-Aging

19th on the list, which puts it at an estimated 1–3% of the formula.

(R*,R*)-.alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (theta,theta)-(+/-)-; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (S-(theta,theta))- (levomenol)

Soothing Anti-Aging

21st on the list, which puts it at an estimated 1–3% of the formula.

Dimethicone

Hydration

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration High

Ingredients that pull and hold water in the upper layers of skin

Barrier support None

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control Low

Ingredients that moderate sebum or absorb shine

Brightening Moderate

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Low

Ingredients aimed at visible redness and reactivity

Cell renewal Moderate

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Photostability Low

A photounstable filter stands without a stabiliser

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (5)

Supporting ingredients (38)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Dihydroxybiphenyl Azelaic Acid Ppg-15 Stearyl Ether Steareth-2 Stearyl Alcohol Ethoxydiglycol Isononyl Isononanoate Glycerin Magnesium Aluminum Silicate 4-butylresorcinol Alpha-arbutin Dimethyl MEA Sorbitol Kojic Acid Bisabolol Glyceryl Dibehenate Dimethicone Caprylic/capric Triglyceride Ppg-25-laureth-25 Steareth-21 Rumex Occidentalis Extract Aminoethylphosphinic Acid Butylene Glycol Dextran Nonapeptide-1 Aloe Barbadensis Leaf Powder Helianthus Annuus Seed Oil Rosmarinus Officinalis Leaf Extract Tocopheryl Acetate Propylene Glycol Dicaprylate/dicaprate Propylene Carbonate Stearalkonium Hectorite Xanthan Gum Disodium Edta Tetrahydropiperine BHT Sodium Metabisulfite

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • No animal-derived ingredients

Contains

  • Silicones

    Dimethicone

  • Facial oils

    Helianthus Annuus Seed Oil

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • AHAs (glycolic, lactic)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • BHA (salicylic acid)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • PHAs (gluconolactone)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Benzoyl peroxide

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Vitamin C (L-ascorbic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • Retinoids (retinol, retinal)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • Azelaic acid

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Moisturise" step.

  • Seal in your serums with it; in the morning, sunscreen still goes on top.
  • It carries UV filters, so it belongs in your morning routine.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Contains Retinyl Palmitate, Alpha-arbutin, Kojic Acid, usually reviewed with a doctor during pregnancy.
Fungal acne (malassezia)
4 ingredients could feed malassezia: Glyceryl Dibehenate, Retinyl Palmitate, Helianthus Annuus Seed Oil, Propylene Glycol Dicaprylate/dicaprate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Pregnancy Unsafe, Silicone

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 43 ingredients on the label.

10
Texture agent

Sets the thickness, spread and stability of the formula

7
Antioxidant

Neutralises free radicals from UV and pollution

7
Emollient

Softens and smooths by filling gaps between skin cells

5
Solvent

Dissolves and carries everything else

5
Surfactant

Lifts oil and dirt, or holds oil and water together

4
Humectant

Draws water into the upper layers of skin

3
Active

Changes how skin behaves rather than how it feels

3
Occlusive

Forms a film that slows water loss

3
pH adjuster

Sets the acidity the formula needs to work

2
Soothing

Calms visible redness and irritation

2
Plant extract

Botanical material, usually for antioxidants or scent

2
Preservative

Keeps the product free of microbial growth

2
UV filter

Absorbs or scatters ultraviolet light

1
Chelator

Binds trace metals that would otherwise spoil the formula

1
Peptide

Amino-acid chains that signal for repair or firmness

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Occlusive

2nd on the list, which puts it at an estimated 5–20% of the formula.

Biphenyl-4,4'-diol

3 Azelaic Acid pH adjuster
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
pH adjuster

3rd on the list, which puts it at an estimated 5–20% of the formula.

Nonanedioic acid

Anti-Acne Dark Spot Fading Smooths Bumpy Skin
8 scientific references
  • Journal of Cosmetic Dermatology, March 2017, pages 35-42
  • The Journal of Clinical and Aesthetic Dermatology, March 2017, pages 37-40
  • Advanced Biomedical Research, February 2017, ePublication
  • Biomedicine & Pharmacotherapy, October 2016, pages 771-775
  • Skin Therapy Letter, January 2016, pages 1-7
  • Cutis, January 2016, pages E9-E11
  • Journal of Drugs in Dermatology, September 2015, pages 964-968
  • International Journal of Toxicology, August 2012, pages 1-72
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

4th on the list, which puts it at an estimated 2–10% of the formula.

Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-octadecyl-.omega.-hydroxy-

5 Titanium Dioxide UV filter
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
UV filter, Texture agent

5th on the list, which puts it at an estimated 2–10% of the formula.

Titanium dioxide (CI 77891)

Anti-Aging
10 scientific references
  • Journal of Cosmetic Dermatology, February 2021, pages 532-537
  • Frontiers in Bioengineering and Biotechnology, June 2020
  • Journal of Nanoparticle Research, March 2020
  • Journal of the European Academy of Dermatology and Venereology, November 2019, pages 34-46
  • Photodermatology, Photoimmunology and Photomedicine, November 2019, pages 442-446
  • Journal of Cosmetic Science, September 2019, pages 223-234
  • Materials, July 2019, pages 1-24
  • Photodermatology, Photoimmunology, and Photomedicine, April 2011, pages 58-67
  • Skin Therapy Letter, July-August 2008, pages 5-7
  • Environmental and Health Perspectives, July 2008, pages 893
6 Steareth-2 Surfactant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

6th on the list, which puts it at an estimated 2–10% of the formula.

Poly(oxy-1,2-ethanediyl), .alpha.-octadecyl-.omega.-hydroxy

7 Stearyl Alcohol Emollient
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Surfactant, Texture agent

7th on the list, which puts it at an estimated 1–5% of the formula.

Octadecan-1-ol

8 Ethoxydiglycol Humectant
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Solvent

8th on the list, which puts it at an estimated 1–5% of the formula.

2-(2-Ethoxyethoxy)ethanol; Carbitol; Diethylene glycol monoethyl ether; DEGEE

Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

9th on the list, which puts it at an estimated 1–5% of the formula.

3,5,5-Trimethylhexyl 3,5,5-trimethylhexanoate

Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
UV filter

10th on the list, which puts it at an estimated 1–5% of the formula.

2-Ethylhexyl 4-methoxycinnamate

Anti-Aging
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
11 Glycerin Humectant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

11th on the list, which puts it at an estimated 1–3% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent

12th on the list, which puts it at an estimated 1–3% of the formula.

Silicic acid, aluminum magnesium salt

Oil Control
3 scientific references
  • The Cosmetic Ingredient Review, March 2021, pages 1-27
  • International Journal of Toxicology, January 2003, pages 37-102
  • International Federation Societies of Cosmetic Chemists, 1997, pages 1-43
13 Niacinamide Active
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

13th on the list, which puts it at an estimated 1–3% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
14 4-butylresorcinol Antioxidant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Antioxidant

14th on the list, which puts it at an estimated 1–3% of the formula.

1,3-Dihydroxy-4-N Butyl Benzene

15 Alpha-arbutin Antioxidant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Antioxidant

15th on the list, which puts it at an estimated 1–3% of the formula.

4-Hydroxyphenyl-alpha-D-glucopyranoside

Anti-Aging Dark Spot Fading Evens Skin Tone
16 Dimethyl MEA pH adjuster
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
pH adjuster

16th on the list, which puts it at an estimated 1–3% of the formula.

2-Dimethylaminoethanol; N,N-Dimethyl-2-aminoethanol

17 Sorbitol Humectant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant

17th on the list, which puts it at an estimated 1–3% of the formula.

D-Glucitol

Hydration
7 scientific references
  • International Journal of Pharmaceutics, January 2019, pages 175–183
  • Clinical Medicine and Research, January 2017, pages 75–87
  • Frontiers in Microbiology, December 2017, ePublication
  • 3 Biotech, June 2012, pages 115-125
  • The Journal of Clinical and Aesthetic Dermatology, August 2011, pages 31-49
  • Applied Biochemistry and Biotechnology, July-September 2004, pages 321-336
  • https://wwwcir-safetyorg/sites/default/files/Mannitol, %20Sorbitol, %20Xylitol_0pdf
18 Kojic Acid Antioxidant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Antioxidant

18th on the list, which puts it at an estimated 1–3% of the formula.

5-Hydroxy-2-hydroxymethyl-4-pyrone

Dark Spot Fading Evens Skin Tone Anti-Aging
19 Bisabolol Soothing
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Soothing

19th on the list, which puts it at an estimated 1–3% of the formula.

(R*,R*)-.alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (theta,theta)-(+/-)-; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (S-(theta,theta))- (levomenol)

Soothing Anti-Aging
6 scientific references
  • CosmeticsInfoorg, Accessed May 2021, ePublication
  • International Journal of Cosmetic Science, August 2019, pages 299-303
  • International Journal of Toxicology, September 2017, pages 24S-25S
  • Cutis, November 2015, pages 337-342
  • Current Pharmaceutical Biotechnology, 2014, pages 173-181
  • Food and Chemical Toxicology, October 2011, pages 2580-2585
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

20th on the list, which puts it at an estimated 1–3% of the formula.

2-Hydroxypropane-1,3-diyl didocosanoate

21 Dimethicone Emollient
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Occlusive

21st on the list, which puts it at an estimated 1–3% of the formula.

Dimethicone

Hydration Silicone
7 scientific references
  • FDA Code of Federal Regulations, April 2020, ePublication
  • International Journal of Toxicology, May 2014, pages 65S-115S
  • The Journal of Clinical and Aesthetic Dermatology, May 2014, pages 36-44
  • Dermatologic Therapy, May 2012, pages 229-233
  • Clinics in Dermatology, May-June 2012, pages 345-348
  • International Journal of Cosmetic Science, January 2008, pages 19-33
  • Skin Research and Technology, May 2000, pages 77-80
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line

22nd on the list, which puts it at an estimated 1–3% of the formula.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration
5 scientific references
  • International Journal of Toxicology, September 2020, pages 34-35
  • Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
  • International Journal of Toxicology, January 2003, pages 4-5
  • Food and Chemical Toxicology, January 2000, pages 79-98
  • Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
23 Ppg-25-laureth-25 Surfactant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

23rd on the list, which puts it at an estimated 1–3% of the formula.

Dodecanol, ethoxylated, propoxylated (2 mol EO, 4 mol PO average molar ratio)

24 Steareth-21 Surfactant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

24th on the list, which puts it at an estimated 1–3% of the formula.

Poly(oxy-1,2-ethanediyl), .alpha.-octadecyl-.omega.-hydroxy

Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Soothing, Plant extract

25th on the list, which puts it at an estimated 1–3% of the formula.

Rumex Occidentalis Extract is an extract of the whole plant, Rumex occidentalis, Polygonaceae

Anti-Aging Dark Spot Fading Evens Skin Tone
26 Ascorbic Acid Active
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Active, Antioxidant, pH adjuster

26th on the list, which puts it at an estimated 1–3% of the formula.

Ascorbic acid

Anti-Aging Dark Spot Fading Evens Skin Tone
12 scientific references
  • Drug Delivery, February 2021, pages 445-453
  • Journal of Cosmetic Dermatology, December 2020, pages 3, 262-3, 269
  • Journal of Oral and Maxillofacial Pathology, May-August 2020, pages 374-382
  • Journal of Cosmetic Dermatology, March 2020, pages 671-676
  • Journal of Clinical and Aesthetic Dermatology, July 2017 pages 14-17
  • Journal of Drugs in Dermatology, July 2016, pages 863-867
  • Clinical, Cosmetic, and Investigational Dermatology, September 2015, pages 463-470
  • Indian Dermatology Online Journal, April-June 2013, pages 143-146
  • AAPS PharmSciTech, July 2011, pages 917-923
  • Journal of Drugs in Dermatology, July 2008, Supplement, pages s2-s6
  • International Journal of Toxicology, Supplement 2, March 2005, pages 51-111
  • Skin Pharmacology and Physiology, July-August 2004, pages 200-206
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line

27th on the list, which puts it at an estimated 1–3% of the formula.

Phosphinic acid, (1-aminoethyl)-

28 Butylene Glycol Humectant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

28th on the list, which puts it at an estimated 1–3% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
29 Dextran Texture agent
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent

29th on the list, which puts it at an estimated 1–3% of the formula.

Dextran

Hydration
1 scientific reference
  • Related Articles
30 Nonapeptide-1 Peptide
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Peptide

30th on the list, which puts it at an estimated 1–3% of the formula.

Nonapeptide-1 is a synthetic nonapeptide derived from arginine, lysine, methionine, phenylalanine, proline, tryptophan and valine

Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

31st on the list, which puts it at an estimated 1–3% of the formula.

Retinol, hexadecanoate

Anti-Aging Pregnancy Unsafe
7 scientific references
  • Antioxidants, November 2020
  • International Journal of Toxicology, October 2017
  • Journal of Biomedical Nanotechnology, February 2016, pages 394-403
  • Acta Biochimica Polonica, 2015, pages 201-206
  • Journal of Lipid Research, July 2013, pages 1, 731–1, 743
  • Clinical Interventions in Aging, December 2006, pages 327-348
  • Journal of Investigative Dermatology, November 2003, pages 1163-1167
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line

32nd on the list, which puts it at an estimated 1–3% of the formula.

Aloe Barbadensis Leaf Powder is the powder obtained from the dried gound leaves of the aloe, Aloe barbadensis, Liliaceae

Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

33rd on the list, which puts it at an estimated 1–3% of the formula.

Helianthus Annuus Seed Oil is the oil expressed from the seeds of the Sunflower, Helianthus annuus L., Compositae

Anti-Aging Hydration
4 scientific references
  • Pediatric Dermatology, August 2018, ePublication; and January-February 2013, pages 42-50
  • Chemicke Zvesti, May 2018, pages 2, 607-2, 615
  • International Journal of Molecular Sciences, December 2017, ePublication
  • Dermatology, October 2014, pages 230-239
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Plant extract, Preservative

34th on the list, which puts it at an estimated 1–3% of the formula.

Rosmarinus Officinalis Leaf Extract is an extract of the leaves of the Rosemary, Rosmarinus officinalis L., Lamiaceae

35 Tocopheryl Acetate Antioxidant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Antioxidant

35th on the list, which puts it at an estimated 1–3% of the formula.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate

Anti-Aging Soothing
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

36th on the list, which puts it at an estimated 1–3% of the formula.

Decanoic acid, mixed diesters with octanoic acid and propylene glycol

Hydration
37 Propylene Carbonate Texture agent
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

37th on the list, which puts it at an estimated 1–3% of the formula.

Propylene carbonate

38 Stearalkonium Hectorite Texture agent
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent

38th on the list, which puts it at an estimated 1–3% of the formula.

Benzenemethanaminium, N,N-dimethyl-N-octadecyl-, chloride, reaction products with hectorite / Quaternary ammonium compounds, benzyl(hydrogenated tallow alkyl)dimethyl, chlorides, compds. with hectorite

39 Xanthan Gum Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant, Texture agent

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Xanthan gum

40 Disodium Edta Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Chelator

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Disodium dihydrogen ethylenediaminetetraacetate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1-Pentanone, 5-(1,3-benzodioxol-5-yl)-1-(piperidinyl)-

42 BHT Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,6-Di-tert-butyl-p-cresol

43 Sodium Metabisulfite Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant, Preservative

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Disodium disulphite

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Frequently asked questions

What ingredients are in melan:off maintenance cream?

WATER, DIHYDROXYBIPHENYL, AZELAIC ACID, PPG-15 STEARYL ETHER, TITANIUM DIOXIDE, STEARETH-2, STEARYL ALCOHOL, ETHOXYDIGLYCOL, ISONONYL ISONONANOATE, ETHYLHEXYL METHOXYCINNAMATE, GLYCERIN, MAGNESIUM ALUMINUM SILICATE, NIACINAMIDE, 4-BUTYLRESORCINOL, ALPHA-ARBUTIN, DIMETHYL MEA, SORBITOL, KOJIC ACID, BISABOLOL, GLYCERYL DIBEHENATE, DIMETHICONE, CAPRYLIC/CAPRIC TRIGLYCERIDE, PPG-25-LAURETH-25, STEARETH-21, RUMEX OCCIDENTALIS EXTRACT, ASCORBIC ACID, AMINOETHYLPHOSPHINIC ACID, BUTYLENE GLYCOL, DEXTRAN, NONAPEPTIDE-1, RETINYL PALMITATE, ALOE BARBADENSIS LEAF POWDER, HELIANTHUS ANNUUS SEED OIL, ROSMARINUS OFFICINALIS LEAF EXTRACT, TOCOPHERYL ACETATE, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, PROPYLENE CARBONATE, STEARALKONIUM HECTORITE, XANTHAN GUM, DISODIUM EDTA, TETRAHYDROPIPERINE, BHT, SODIUM METABISULFITE.

What are the active ingredients in melan:off maintenance cream?

NIACINAMIDE, ASCORBIC ACID, RETINYL PALMITATE.

How do I use melan:off maintenance cream?

Apply it after serums. Seal in your serums with it; in the morning, sunscreen still goes on top. It carries UV filters, so it belongs in your morning routine.

What skin types is melan:off maintenance cream good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry), Combination (oily), Oily skin.

Is melan:off maintenance cream good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is melan:off maintenance cream fungal acne safe?

4 ingredients could feed malassezia: Glyceryl Dibehenate, Retinyl Palmitate, Helianthus Annuus Seed Oil, Propylene Glycol Dicaprylate/dicaprate. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use melan:off maintenance cream while pregnant?

It contains Retinyl Palmitate, Alpha-arbutin, Kojic Acid, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.

Is melan:off maintenance cream fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does melan:off maintenance cream contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is melan:off maintenance cream silicone free?

No — it contains Dimethicone.

Does melan:off maintenance cream contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is melan:off maintenance cream paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with melan:off maintenance cream?

It layers well with Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides, Signal peptides. Take more care combining it with AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide, Vitamin C (L-ascorbic acid), Retinoids (retinol, retinal), Azelaic acid — use them in separate routines or on alternate days.

When should I apply melan:off maintenance cream?

Use it morning and evening, after serums.

How many ingredients does melan:off maintenance cream have?

It lists 43 ingredients, of which 5 are recorded as actives.

Who makes melan:off maintenance cream?

md:ceuticals.

What UV filters are in melan:off maintenance cream?

It filters UV with Titanium Dioxide (titanium dioxide), Octinoxate (ethylhexyl methoxycinnamate).

Is melan:off maintenance cream broad spectrum?

Not in the strictest sense. Its filters stop short of UVA I (340–400 nm), the deepest ageing wavelengths.

Does melan:off maintenance cream leave a white cast?

It may leave a slight cast. The formula mixes mineral and organic filters, so any cast is usually lighter than a fully mineral sunscreen's.

Is melan:off maintenance cream reef safe?

It contains Octinoxate, which are named in the Hawaii and Key West reef legislation. Some destinations restrict sunscreens containing them.

Can I wear melan:off maintenance cream under makeup?

Yes. Let it set for a couple of minutes before foundation so it does not pill, and reapply over makeup with a stick or powder rather than rubbing more in.

How often should I reapply melan:off maintenance cream?

More often than the usual advice. It carries a photounstable filter with no stabiliser beside it, so protection can drop within the first hour of direct sun — reapply at least every two hours, and sooner in strong sun.

Brand
md:ceuticals

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