1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Medicube
One Day Exosome Shot 25000
face serum
Medicube
face serum
Added Last edited
Fit by skin type
General, ingredient-based — not your personalized match.
See how this fits your skin
Take the skin test and I'll show you how suitable this product is for you.
Take the skin testMedicube One Day Exosome Shot 25000 is an intensive weekly pore care serum that smooths skin texture and helps minimize the appearance of pores. Formulated with Hydrolyzed Sponge, Lactobacillus Extracellular Vesicles, Milk Exosomes, Niacinamide, Gluconolactone, Betaine Salicylate, Ceramide NP, and peptides, this treatment works to gently resurface, clear congested pores, and support the skin barrier for a smoother, more refined complexion. The unique micro-spicule technology helps deliver key ingredients deeper into the skin, while hydrating and barrier-supporting ingredients help keep skin comfortable after use.
One Day Exosome Shot 25000 is a lightweight serum from Medicube, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 42 ingredients, each broken down in full below.
By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Hydration is handled by Butylene Glycol, Glycerin and Panthenol, humectants that pull water into the upper layers of skin rather than sealing it there.
Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Butylene Glycol, Glycerin, Panthenol and Ethylhexylglycerin.
Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Panthenol, Niacinamide, Adenosine and Ulmus Davidiana Root Extract.
Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Panthenol, Hydrogenated Lecithin and Ceramide NP.
Oil control: Moderate. Ingredients that moderate sebum or absorb shine, and here that comes from Niacinamide and Calcium Aluminum Borosilicate.
On richness alone it suits Balanced skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.
The formula contributes little or nothing on antioxidant protection. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.
Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, silicone-free and microplastic-free. Those claims come from the ingredient list itself, not from the packaging.
It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.
This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.
Drawn purely from the ingredient list
Scored on how rich or light the formula reads from its INCI order.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Based on the curated benefits documented for this product's ingredients.
Attracts and locks in moisture to keep skin plump and dewy
Boosts collagen and cell turnover to reduce fine lines and wrinkles
Calms redness, irritation, and inflammation for sensitive skin
Brightens and balances complexion for a more uniform appearance
Targets breakouts by reducing bacteria and unclogging pores
Tightens and refines the look of enlarged pores
None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.
The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
Poly(oxy-1,2-ethanediyl)], .alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxy-
4th on the list, which puts it at an estimated 2–10% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
5th on the list, which puts it at an estimated 2–10% of the formula.
Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl
6th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ulmus Davidiana Root Extract is an extract of the root bark of the Elm, Ulmus davidiana, Ulmaceae
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Pueraria Lobata Root Extract is an extract of the roots of Pueraria lobata, Fabacea
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
D-Glucono-1,5-lactone
Each axis is scored from the ingredients present and how high up the list they sit.
Ingredients that pull and hold water in the upper layers of skin
Lipids and repair signals that support skin barrier integrity
Ingredients that mop up free radicals from UV and pollution
Ingredients that moderate sebum or absorb shine
Ingredients that act on uneven tone and post-inflammatory marks
Ingredients aimed at visible redness and reactivity
Retinoids, acids and enzymes that speed surface turnover
Peptides and growth factors that signal for collagen support
"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.
Solvents, emollients, texture agents and preservatives — the formula that carries the actives.
Read from the full ingredient list. A brand's own claim may differ.
Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
This product is the "Treat" step.
Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.
Most ingredients do more than one job, so these counts add up to more than the 42 ingredients on the label.
Sets the thickness, spread and stability of the formula
Botanical material, usually for antioxidants or scent
Changes how skin behaves rather than how it feels
Dissolves and carries everything else
Draws water into the upper layers of skin
Lifts oil and dirt, or holds oil and water together
Softens and smooths by filling gaps between skin cells
Binds trace metals that would otherwise spoil the formula
Amino-acid chains that signal for repair or firmness
Forms a film that slows water loss
Sets the acidity the formula needs to work
Loosens or dissolves dead surface cells
Keeps the product free of microbial growth
Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
Poly(oxy-1,2-ethanediyl)], .alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxy-
3rd on the list, which puts it at an estimated 5–20% of the formula.
1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol
4th on the list, which puts it at an estimated 2–10% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
5th on the list, which puts it at an estimated 2–10% of the formula.
Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl
6th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
7th on the list, which puts it at an estimated 1–5% of the formula.
Hydrolyzed Sponge is the hydrolysate of sponge obtained by acid, enzyme or other method of hydrolysis
8th on the list, which puts it at an estimated 1–5% of the formula.
Calcium Aluminium Borosilicate is a glass consisting essentially of calcium and aluminium borosilicates
9th on the list, which puts it at an estimated 1–5% of the formula.
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate monomers
10th on the list, which puts it at an estimated 1–5% of the formula.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium hydroxyethyl acrylate and acryloyldimethyl taurate monomers
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octane-1,2-diol
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Isohexadecane is a branched chain aliphatic hydrocarbon with 16 carbons.
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sorbitan, mono-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs., (Z)-
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sorbitan oleate
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sorbitan, isooctadecanoate
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs.
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Disodium dihydrogen ethylenediaminetetraacetate
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lactobacillus Extracellular Vesicles are the extracellular vesicles released into and isolated from the growth media removed from cell cultures of the microorganism Lactobacillus.
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Kummerowia Striata Extract is the extract of the whole plant, Kummerowia striata, Fabaceae
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Oenothera Biennis Flower Extract is an extract of the flowers of the Evening Primrose, Oenothera biennis, Onagraceae
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ulmus Davidiana Root Extract is an extract of the root bark of the Elm, Ulmus davidiana, Ulmaceae
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Pinus Palustris Leaf Extract is an extract of the needles of the Swamp Pine, Pinus palustris, Pinaceae
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Pueraria Lobata Root Extract is an extract of the roots of Pueraria lobata, Fabacea
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cinchona Pubescens Bark Extract is an extract of the bark of Cinchona pubescens, Rubiaceae
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
D-Glucono-1,5-lactone
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Betaine Salycilate is the product formed by the reaction of Betaine with Salycilic Acid
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Hydroxy-1,2,3-propanetricarboxylic acid
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Milk Exosomes
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Leptospermum Scoparium Leaf Extract is an extract of the leaves of Leptospermum scoparium, Myrtaceae
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lecithins, hydrogenated
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio)
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl Tetrapeptide-5 is product obtained by the acetylation of Tetrapeptide-5
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lysine, synthetic pentapeptide with serine, and threonine, hexadecanoyl derivatives
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Palmitoyl Tripeptide-5 is the reaction product of palmitic acid and Tripeptide-5
Products in the same category that share this formula's distinguishing ingredients.
Arencia
Shares 11 key ingredients with One Day Exosome Shot 25000: Water, Glycereth-26, Glycerin, Niacinamide, Ceramide NP
Eqqualberry
Shares 11 key ingredients with One Day Exosome Shot 25000: Water, Butylene Glycol, Glycereth-26, Niacinamide, Glycerin
Anua
Shares 11 key ingredients with One Day Exosome Shot 25000: Water, Glycereth-26, Niacinamide, Glycerin, Caprylic/capric Triglyceride
Arencia
Shares 10 key ingredients with One Day Exosome Shot 25000: Water, Butylene Glycol, Glycerin, Niacinamide, Ceramide NP
Arencia
Shares 10 key ingredients with One Day Exosome Shot 25000: Water, Glycerin, Niacinamide, Panthenol, Butylene Glycol
Numbuzin
Shares 10 key ingredients with One Day Exosome Shot 25000: Water, Niacinamide, Butylene Glycol, Glycerin, Caprylic/capric Triglyceride
WATER, GLYCERETH-26, DIPROPYLENE GLYCOL, BUTYLENE GLYCOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, NIACINAMIDE, HYDROLYZED SPONGE, CALCIUM ALUMINUM BOROSILICATE, SODIUM ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, 1,2-HEXANEDIOL, CAPRYLYL GLYCOL, ISOHEXADECANE, GLYCERIN, POLYSORBATE 80, CARBOMER, TROMETHAMINE, PANTHENOL, ETHYLHEXYLGLYCERIN, ADENOSINE, SORBITAN OLEATE, SORBITAN ISOSTEARATE, POLYSORBATE 60, DISODIUM EDTA, LACTOBACILLUS EXTRACELLULAR VESICLES, KUMMEROWIA STRIATA EXTRACT, OENOTHERA BIENNIS FLOWER EXTRACT, ULMUS DAVIDIANA ROOT EXTRACT, PINUS PALUSTRIS LEAF EXTRACT, PUERARIA LOBATA ROOT EXTRACT, CINCHONA PUBESCENS BARK EXTRACT, GLUCONOLACTONE, BETAINE SALICYLATE, CITRIC ACID, MILK EXOSOMES, LEPTOSPERMUM SCOPARIUM LEAF EXTRACT, HYDROGENATED LECITHIN, POLYGLYCERYL-10 LAURATE, CERAMIDE NP, ACETYL TETRAPEPTIDE-5, PALMITOYL PENTAPEPTIDE-4, PALMITOYL TRIPEPTIDE-5.
NIACINAMIDE, PANTHENOL, GLUCONOLACTONE, CITRIC ACID, CERAMIDE NP, PALMITOYL PENTAPEPTIDE-4.
Use once every 7 days, in the evening after cleansing. Take an appropriate amount and apply it to bare skin. Avoid the eye and lip areas. Use it as the first step of your skincare routine. Gently massage into the skin until absorbed. Follow with your favorite moisturizer to finish.
Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry) skin.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
6 ingredients could feed malassezia: Polysorbate 80, Sorbitan Oleate, Sorbitan Isostearate, Polysorbate 60, Lactobacillus Extracellular Vesicles, Polyglyceryl-10 Laurate. That describes the yeast's food supply, not a prediction that they will cause a breakout.
Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.
Yes. Reading the full ingredient list, this formula is fragrance-free.
No. Reading the full ingredient list, this formula is no drying alcohol.
Yes. Reading the full ingredient list, this formula is silicone-free.
No. Reading the full ingredient list, this formula is essential-oil-free.
Yes. Reading the full ingredient list, this formula is paraben-free.
It layers well with Vitamin C (L-ascorbic acid), Benzoyl peroxide, Azelaic acid, Copper peptides, Bakuchiol, Niacinamide. Take more care combining it with Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone) — use them in separate routines or on alternate days.
Use it morning and evening, after toner, before moisturiser.
It lists 42 ingredients, of which 6 are recorded as actives.
Medicube, a brand based in Korea.
We can't find the internet
Attempting to reconnect
Something went wrong!
Attempting to reconnect