Aestura A-Cica 365 Soothing Relief Serum pH4.5

Aestura

A-Cica 365 Soothing Relief Serum pH4.5

face serum

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Fit by skin type

General, ingredient-based — not your personalized match.

Dry
53%
Combination (dry)
53%
Balanced
82%
Combination (oily)
88%
Oily
88%

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32
Ingredients
6
Benefits
4
Actives
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The AESTURA A-Cica 365 Soothing Relief Serum pH4.5 is a calming, barrier-supporting treatment designed to reduce redness, soothe irritation, and rebalance sensitive or acne-prone skin. Formulated at an optimal pH 4.5, this lightweight serum helps maintain the skin’s natural protective environment while strengthening resilience against external stressors. Powered by the A-Cica Complex and centella-derived actives, it delivers targeted relief to compromised or reactive skin.

Key Insights

Benefits

6
Anti-Aging
Dark Spot Fading
Evens Skin Tone
Hydration
Pore Minimizer
Soothing

Active Ingredients

4
PHA Hyaluronic acid Vitamin B3 (niacinamide) Vitamin C

Risks

2
Silicone
Synthetic polymer

About A-Cica 365 Soothing Relief Serum pH4.5

Overview

A-Cica 365 Soothing Relief Serum pH4.5 is a lightweight serum from Aestura, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 32 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Glycerin, Butylene Glycol and Betaine, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Butylene Glycol, Betaine and Ethylhexylglycerin.

Brightening: Moderate. Ingredients that act on uneven tone and post-inflammatory marks, and here that comes from Niacinamide, 3-o-ethyl Ascorbic Acid and Gluconolactone.

Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Squalane, Hydrogenated Lecithin and Cholesterol.

Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Asiaticoside, Madecassoside, Niacinamide and Madecassic Acid.

Who it suits

On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on antioxidant protection and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • 4 ingredients could feed malassezia (fungal acne)

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin
  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 16 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 11 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 5 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Evens Skin Tone 2 ingredients

    Brightens and balances complexion for a more uniform appearance

  • Dark Spot Fading 1 ingredient

    Fades hyperpigmentation and evens out dark spots over time

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

Does not target

Anti-Acne Blackhead Reducing Oil Control Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

2nd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

3rd on the list, which puts it at an estimated 5–20% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration

5th on the list, which puts it at an estimated 2–10% of the formula.

Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt

Hydration
Niacinamide Vitamin B3 (niacinamide)

6th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

7th on the list, which puts it at an estimated 1–5% of the formula.

D-Glucono-1,5-lactone

Evens Skin Tone Anti-Aging Hydration

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sucrose stearate

Hydration

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,6,10,15,19,23-Hexamethyltetracosane

Hydration Anti-Aging

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, hydrogenated

Hydration

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2,3-Propanetriol, homopolymer, octadecanoates (1:1) (10 mol glycerol average molar ratio)

Hydration

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,1,3,5,5,5-Heptamethyl-3-octyl-trisiloxane

Hydration

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration High

Ingredients that pull and hold water in the upper layers of skin

Barrier support Moderate

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control Low

Ingredients that moderate sebum or absorb shine

Brightening Moderate

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Moderate

Ingredients aimed at visible redness and reactivity

Cell renewal Low

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (4)

Supporting ingredients (28)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Glycerin Butylene Glycol Dipropylene Glycol Betaine 1,2-hexanediol Diethoxyethyl Succinate Tromethamine Sucrose Stearate Squalane Hydrogenated Lecithin Polyglyceryl-10 Stearate Polyglyceryl-10 Laurate Carbomer Caprylyl Methicone Polyacrylate Crosspolymer-6 Ethylhexylglycerin Cholesterol Xanthan Gum Asiaticoside Madecassic Acid Asiatic Acid Cellulose Gum Zinc PCA Sodium Gluconate Glyceryl Caprylate Madecassoside Sodium Trimetaphosphate

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • Oil-free
  • No animal-derived ingredients

Contains

  • Silicones

    Caprylyl Methicone

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Vitamin C (L-ascorbic acid)
  • Benzoyl peroxide
  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • Retinoids (retinol, retinal)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • AHAs (glycolic, lactic)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • BHA (salicylic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • PHAs (gluconolactone)

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Treat" step.

  • Apply to clean, dry skin and give it a minute to absorb before the next layer.
  • Introduce one new treatment at a time so you can identify what is working.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Nothing in this formula is on the standard pregnancy-caution list. That is not clearance — ask your doctor about anything you use daily.
Fungal acne (malassezia)
4 ingredients could feed malassezia: Sucrose Stearate, Polyglyceryl-10 Stearate, Polyglyceryl-10 Laurate, Glyceryl Caprylate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 32 ingredients on the label.

9
Texture agent

Sets the thickness, spread and stability of the formula

6
Solvent

Dissolves and carries everything else

5
Humectant

Draws water into the upper layers of skin

5
Surfactant

Lifts oil and dirt, or holds oil and water together

4
Active

Changes how skin behaves rather than how it feels

4
Emollient

Softens and smooths by filling gaps between skin cells

3
Chelator

Binds trace metals that would otherwise spoil the formula

2
Antioxidant

Neutralises free radicals from UV and pollution

2
Occlusive

Forms a film that slows water loss

2
pH adjuster

Sets the acidity the formula needs to work

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Glycerin Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
3 Butylene Glycol Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
4 Dipropylene Glycol Texture agent
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

4th on the list, which puts it at an estimated 2–10% of the formula.

1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol

5 Betaine Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent

5th on the list, which puts it at an estimated 2–10% of the formula.

Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt

Hydration
5 scientific references
  • International Journal of Toxicology, 2018, pages 28S-46S
  • Food Science and Biotechnology, October 2017, pages 1391-1397
  • The Journal of Chemical Physics, June 2015, ePublication
  • The American Journal of Clinical Nutrition, September 2004, pages 539-549
  • Skin Research and Technology, February 2003, pages 50-58
6 Niacinamide Active
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

6th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Active, Chelator

7th on the list, which puts it at an estimated 1–5% of the formula.

D-Glucono-1,5-lactone

Evens Skin Tone Anti-Aging Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanedioic acid, bis(2-ethoxyethyl) ester

10 Tromethamine pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

11 Sucrose Stearate Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sucrose stearate

Hydration
12 Squalane Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,6,10,15,19,23-Hexamethyltetracosane

Hydration Anti-Aging
9 scientific references
  • Cosmetics Ingredient Review, 2019, ePublication
  • ACS Open, July 2017, pages 3, 989–3, 996
  • Indian Journal of Dermatology, May-June 2016, pages 279-297
  • The Journal of Clinical and Aesthetic Dermatology, June 2014, pages 25-32
  • Journal of Cosmetic Science, January-February 2013, pages 59-66
  • Advances in Food and Nutrition Research, 2012, pages 223-233
  • Molecules, January 2009, pages 540-554
  • Journal of Investigative Dermatology, November 2006, pages 2, 430-2, 437
  • Free Radical Research, April 2002, pages 471-477
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, hydrogenated

Hydration
4 scientific references
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Nanocosmetics, June 2019, pages 95–140
  • Current Drug Delivery, 2016, pages 111–120
  • Pharmaceutical Research, February 2013, pages 538–55
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2,3-Propanetriol, homopolymer, octadecanoates (1:1) (10 mol glycerol average molar ratio)

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio)

16 Carbomer Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,1,3,5,5,5-Heptamethyl-3-octyl-trisiloxane

Hydration Silicone
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Polyacrylate Crosspolymer-6 is a copolymer of ammonium acryloyldimethyltaurate, dimethylacrylamide, lauryl methacrylate and laureth-4 methacrylate, crosslinked with trimethylolpropane triacrylate

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
20 Cholesterol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant, Texture agent

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cholest-5-en-3-ol (beta)-

Hydration Anti-Aging
4 scientific references
  • Frontiers in Bioengineering and Biotechnology, August 2015, pages 1-6
  • Journal of Cosmetic Dermatology, July 2007, pages 239-242
  • Journal of Structural Biology, June 2007, pages 386-400
  • International Journal of Toxicology, 2006, pages 1-89
21 Xanthan Gum Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant, Texture agent

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Xanthan gum

22 Asiaticoside Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester (2alpha, 3beta, 4alpha)-

Anti-Aging Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-

Anti-Aging Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

(2.alpha.,3.beta.,4.alpha.)-2,3,23-Trihydroxyurs-12-en-28-oic acid

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
26 Cellulose Gum Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cellulose, carboxymethyl ether, sodium salt

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3-O-Ethyl Ascorbic Acid is the organic compound.

Anti-Aging Evens Skin Tone Dark Spot Fading
5 scientific references
  • Free Radical Biology and Medicine, September 2021, pages 151–169
  • Life, May 2021, pages 1–13
  • International Journal of Pharmaceutics, December 2019, pages 1–9
  • Journal of Cosmetic Science, July-August 2018, pages 233–243
  • AAPS PharmSciTech, June 2016, pages 767–777
28 Zinc PCA Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Proline, 5-oxo-, zinc salt

Hydration
29 Sodium Gluconate Chelator
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Chelator

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium gluconate

Hydration
3 scientific references
  • International Journal of Toxicology, May/June 2019, pages 5S-38S
  • Journals of Materials Research, February 2006, pages 343-348
  • https://wwwepagov/sites/production/files/2019-08/documents/support_document_for_proposed_designation_of_d-gluconic_acid_sodium_saltpdf
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Octanoic acid, monoester with glycerol

Hydration
31 Madecassoside Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

O-6-Deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oate

Anti-Aging Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Chelator, pH adjuster

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Trisodium trimetaphosphate

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Frequently asked questions

What ingredients are in A-Cica 365 Soothing Relief Serum pH4.5?

WATER, GLYCERIN, BUTYLENE GLYCOL, DIPROPYLENE GLYCOL, BETAINE, NIACINAMIDE, GLUCONOLACTONE, 1,2-HEXANEDIOL, DIETHOXYETHYL SUCCINATE, TROMETHAMINE, SUCROSE STEARATE, SQUALANE, HYDROGENATED LECITHIN, POLYGLYCERYL-10 STEARATE, POLYGLYCERYL-10 LAURATE, CARBOMER, CAPRYLYL METHICONE, POLYACRYLATE CROSSPOLYMER-6, ETHYLHEXYLGLYCERIN, CHOLESTEROL, XANTHAN GUM, ASIATICOSIDE, MADECASSIC ACID, ASIATIC ACID, SODIUM HYALURONATE, CELLULOSE GUM, 3-O-ETHYL ASCORBIC ACID, ZINC PCA, SODIUM GLUCONATE, GLYCERYL CAPRYLATE, MADECASSOSIDE, SODIUM TRIMETAPHOSPHATE.

What are the active ingredients in A-Cica 365 Soothing Relief Serum pH4.5?

NIACINAMIDE, GLUCONOLACTONE, SODIUM HYALURONATE, 3-O-ETHYL ASCORBIC ACID.

How do I use A-Cica 365 Soothing Relief Serum pH4.5?

After cleansing and toning, apply 1–2 pumps evenly to the face. Gently pat until fully absorbed, then follow with moisturizer. Use morning and evening.

What skin types is A-Cica 365 Soothing Relief Serum pH4.5 good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is A-Cica 365 Soothing Relief Serum pH4.5 good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is A-Cica 365 Soothing Relief Serum pH4.5 fungal acne safe?

4 ingredients could feed malassezia: Sucrose Stearate, Polyglyceryl-10 Stearate, Polyglyceryl-10 Laurate, Glyceryl Caprylate. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use A-Cica 365 Soothing Relief Serum pH4.5 while pregnant?

Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.

Is A-Cica 365 Soothing Relief Serum pH4.5 fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does A-Cica 365 Soothing Relief Serum pH4.5 contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is A-Cica 365 Soothing Relief Serum pH4.5 silicone free?

No — it contains Caprylyl Methicone.

Does A-Cica 365 Soothing Relief Serum pH4.5 contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is A-Cica 365 Soothing Relief Serum pH4.5 paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with A-Cica 365 Soothing Relief Serum pH4.5?

It layers well with Vitamin C (L-ascorbic acid), Benzoyl peroxide, Azelaic acid, Copper peptides, Bakuchiol, Niacinamide. Take more care combining it with Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone) — use them in separate routines or on alternate days.

When should I apply A-Cica 365 Soothing Relief Serum pH4.5?

Use it morning and evening, after toner, before moisturiser.

How many ingredients does A-Cica 365 Soothing Relief Serum pH4.5 have?

It lists 32 ingredients, of which 4 are recorded as actives.

Who makes A-Cica 365 Soothing Relief Serum pH4.5?

Aestura, a brand based in Korea.

Brand
Aestura
Country
Korea

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