Genabelle PDRN Rejuvenating Cream

Genabelle

PDRN Rejuvenating Cream

face cream

Added Last edited

Fit by skin type

General, ingredient-based — not your personalized match.

Dry
62%
Combination (dry)
62%
Balanced
92%
Combination (oily)
78%
Oily
78%

See how this fits your skin

Take the skin test and I'll show you how suitable this product is for you.

Take the skin test
45
Ingredients
6
Benefits
6
Actives
Find Dupes

The Genabelle PDRN Rejuvenating Cream is a rich hydrating face cream that helps strengthen the skin barrier while supporting elasticity and softness. This nourishing cream is packed with skin-loving PDRN (Sodium DNA), niacinamide, hyaluronic acid, ceramide NP, peptides, and panthenol to keep skin feeling plump, smooth, and comfortably hydrated.

Key Insights

Benefits

6
Anti-Aging
Evens Skin Tone
Hydration
Oil Control
Pore Minimizer
Soothing

Active Ingredients

6
Ceramides Hyaluronic acid Neuropeptides Signal peptides Vitamin B3 (niacinamide) Vitamin B5 (panthenol)

Risks

2
Silicone
Synthetic polymer

About PDRN Rejuvenating Cream

Overview

PDRN Rejuvenating Cream is a lightweight cream from Genabelle. The formula is built mainly around hydration and soothing. The ingredient list runs to 45 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Glycerin, Butylene Glycol and Sodium Hyaluronate, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: Very high. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Butylene Glycol, Sodium Hyaluronate and Panthenol.

Soothing: High. Ingredients aimed at visible redness and reactivity, and here that comes from Panthenol, Centella Asiatica Extract, Chamomilla Recutita Flower Extract and Oenothera Biennis Oil.

Who it suits

On richness alone it suits Balanced skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on antioxidant protection and cell renewal. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is essential-oil-free, no drying alcohol, paraben-free, microplastic-free, sulfate-free and dye-free. Those claims come from the ingredient list itself, not from the packaging. It does contain fragrance, worth knowing if your skin reacts to any of them.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after serums. Seal in your serums with it; in the morning, sunscreen still goes on top.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No essential oils
  • No drying alcohol
  • No microplastics
  • Strong humectant content for hydration
  • Several soothing ingredients
  • No common irritants flagged in the list

Things to know

  • Contains fragrance or declared fragrance allergens
  • 2 ingredients could feed malassezia (fungal acne)

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin

May suit

  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 21 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 14 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 10 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Evens Skin Tone 1 ingredient

    Brightens and balances complexion for a more uniform appearance

  • Oil Control 1 ingredient

    Regulates sebum production to reduce shine and greasiness

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

Does not target

Anti-Acne Blackhead Reducing Dark Spot Fading Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

3rd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

4th on the list, which puts it at an estimated 2–10% of the formula.

1,1,5,5,5-Hexamethyl-3-phenyl-3-[(trimethylsilyl)oxy]trisiloxane

Hydration

5th on the list, which puts it at an estimated 2–10% of the formula.

Oenothera Biennis Oil is the fixed oil derived from the seeds of the Evening Primrose, Oenothera biennis, Onagraceae

Hydration Anti-Aging Soothing

6th on the list, which puts it at an estimated 2–10% of the formula.

Alcohols, C16-18

Hydration

7th on the list, which puts it at an estimated 1–5% of the formula.

alpha-D-Glucopyranoside, 2-Hydroxy-1-(Hydroxymethyl)ethyl

Hydration Soothing
Niacinamide Vitamin B3 (niacinamide)

8th on the list, which puts it at an estimated 1–5% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

9th on the list, which puts it at an estimated 1–5% of the formula.

Beeswax. The wax obtained from the honeycomb of the bee. It consists primarily of myricyl palmitate, cerotic acid and esters and some high-carbon paraffins

Hydration

11th on the list, which puts it at an estimated 1–3% of the formula.

L-Arginine

Hydration Anti-Aging

12th on the list, which puts it at an estimated 1–3% of the formula.

Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone

Anti-Aging Hydration

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Stearic acid, monoester with glycerol

Hydration

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, homopolymer, sodium salt

Oil Control

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration Very high

Ingredients that pull and hold water in the upper layers of skin

Barrier support Low

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control Low

Ingredients that moderate sebum or absorb shine

Brightening Low

Ingredients that act on uneven tone and post-inflammatory marks

Soothing High

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling Low

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (7)

Supporting ingredients (38)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Dipropylene Glycol Glycerin Phenyl Trimethicone Oenothera Biennis Oil Cetearyl Alcohol Glyceryl Glucoside Cera Alba Peg-100 Stearate Arginine Hydroxyacetophenone 1,2-hexanediol Glyceryl Stearate Sodium Polyacrylate Carbomer Dimethicone Hydrogenated Polydecene Lauryl Peg-9 Polydimethylsiloxyethyl Dimethicone Sodium DNA Dimethicone/vinyl Dimethicone Crosspolymer Butylene Glycol Parfum Adenosine Trideceth-6 Disodium Edta Pentylene Glycol Hydrolyzed Sodium DNA Tocopherol Uracil Thymine Adenine Centella Asiatica Extract Hydrogenated Lecithin Portulaca Oleracea Extract Chamomilla Recutita Flower Extract Vitex Agnus-castus Extract Guanine Cytosine

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • Oil-free

Contains

  • Fragrance

    Parfum

  • Silicones

    Phenyl Trimethicone, Dimethicone, Lauryl Peg-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/vinyl Dimethicone Crosspolymer

  • Animal-derived ingredients

    Cera Alba

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Vitamin C (L-ascorbic acid)
  • Retinoids (retinol, retinal)
  • AHAs (glycolic, lactic)
  • BHA (salicylic acid)
  • PHAs (gluconolactone)
  • Benzoyl peroxide
  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Nothing in this formula belongs to a group our rules can put in conflict, so it layers freely. Order still matters — thinnest texture first.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Moisturise" step.

  • Seal in your serums with it; in the morning, sunscreen still goes on top.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Nothing in this formula is on the standard pregnancy-caution list. That is not clearance — ask your doctor about anything you use daily.
Fungal acne (malassezia)
2 ingredients could feed malassezia: Peg-100 Stearate, Glyceryl Stearate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 45 ingredients on the label.

9
Texture agent

Sets the thickness, spread and stability of the formula

8
Surfactant

Lifts oil and dirt, or holds oil and water together

7
Active

Changes how skin behaves rather than how it feels

7
Emollient

Softens and smooths by filling gaps between skin cells

7
Solvent

Dissolves and carries everything else

6
Humectant

Draws water into the upper layers of skin

5
Occlusive

Forms a film that slows water loss

4
Plant extract

Botanical material, usually for antioxidants or scent

2
Antioxidant

Neutralises free radicals from UV and pollution

2
Peptide

Amino-acid chains that signal for repair or firmness

1
Fragrance / colour

Changes how the product smells or looks

1
Soothing

Calms visible redness and irritation

1
Chelator

Binds trace metals that would otherwise spoil the formula

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Dipropylene Glycol Texture agent
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol

3 Glycerin Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line

4th on the list, which puts it at an estimated 2–10% of the formula.

1,1,5,5,5-Hexamethyl-3-phenyl-3-[(trimethylsilyl)oxy]trisiloxane

Hydration Silicone
5 scientific references
  • International Journal of Toxicology, 2006, pages 1-89
  • https://onlinepersonalcarecouncilorg/ctfa-static/online/lists/cir-pdfs/PRNS513pdf
  • Journal of Cosmetic Science, June 2003, pages 335-351
  • Silicone Surfactants, 1999, page 190
  • International Journal of Toxicology, 1986, pages 353-371
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

5th on the list, which puts it at an estimated 2–10% of the formula.

Oenothera Biennis Oil is the fixed oil derived from the seeds of the Evening Primrose, Oenothera biennis, Onagraceae

Hydration Anti-Aging Soothing
2 scientific references
  • Journal of Pharmaceutical Sciences, January 2016, pages 188-193
  • Annals of Dermatology, December 2014, pages 706-712
6 Cetearyl Alcohol Emollient
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Surfactant, Texture agent

6th on the list, which puts it at an estimated 2–10% of the formula.

Alcohols, C16-18

Hydration
4 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • FDA Cosmetic Labeling Claims, August 2020, ePublication
  • Journal of the Society of Cosmetic Scientists of Korea, June 2009, pages 103-110
  • Journal of the American College of Toxicology, 1988, pages 359-413
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant

7th on the list, which puts it at an estimated 1–5% of the formula.

alpha-D-Glucopyranoside, 2-Hydroxy-1-(Hydroxymethyl)ethyl

Hydration Soothing
4 scientific references
  • Health Science Reports, April 2021, pages 1–7
  • Antioxidants, February 2020, pages 1–20
  • The Journal of Clinical and Aesthetic Dermatology, August 2012, pages 29–39
  • Skin Pharmacology and Physiology, May 2012, pages 192–199
8 Niacinamide Active
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

8th on the list, which puts it at an estimated 1–5% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
9 Cera Alba Emollient
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Occlusive, Surfactant

9th on the list, which puts it at an estimated 1–5% of the formula.

Beeswax. The wax obtained from the honeycomb of the bee. It consists primarily of myricyl palmitate, cerotic acid and esters and some high-carbon paraffins

Hydration
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
10 Peg-100 Stearate Surfactant
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

10th on the list, which puts it at an estimated 1–5% of the formula.

Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- (100 mol EO average molar ratio)

Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line

11th on the list, which puts it at an estimated 1–3% of the formula.

L-Arginine

Hydration Anti-Aging
6 scientific references
  • Biobased Surfactants (Second Edition), 2019, pages 413-445
  • Scientific Reports, February 2016, pages 1-10
  • Cosmetic Ingredient Review, October 2012, pages 1-35
  • Journal of Advanced Research, July 2010, pages 169–177
  • International Journal of Cosmetic Science, April 2005, page 139
  • Wound Repair and Regeneration, November-December 2003, pages 419-423
12 Hydroxyacetophenone Antioxidant
Estimated level
1–3%
Confidence
Moderate — INCI order above the 1% line
Roles
Antioxidant

12th on the list, which puts it at an estimated 1–3% of the formula.

Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone

Anti-Aging Hydration
4 scientific references
  • Journal of Oleo Science, February 2019, pages 183-191
  • Applied Environmental Microbiology, June 2018, ePublication
  • Journal of Biosciences, May-June 2004, pages 345-353
  • Scientific Reports, April 2021, pages 1–7
13 1,2-hexanediol Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

14 Glyceryl Stearate Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Stearic acid, monoester with glycerol

Hydration
3 scientific references
  • Cosmeticsinfoorg, Accessed November 2021, ePublication
  • Drugs in Context, April 2018, pages 1-14
  • International Journal of Toxicology, May 2007, pages 1–30
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Occlusive, Texture agent

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, homopolymer, sodium salt

Oil Control Synthetic polymer
7 scientific references
  • International Food Research Journal, February 2021, pages 44 - 55
  • Journal of Nanoscience and Nanotechnology, March 2018, pages 1, 611-1, 614
  • Industrial & Engineering Chemistry Research, November 2014, pages 18, 346-18, 351
  • Journal of Applied Polymer Science, November 2001, pages 1, 515-1, 520
  • United States Patent, April 2000, ePublication
  • https://wwwsocochemcom/is-sodium-polyacrylate-safehtml
  • https://wwwcir-safetyorg/sites/default/files/acryco092018TARpdf
16 Carbomer Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether

Synthetic polymer
17 Dimethicone Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Occlusive

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dimethicone

Hydration Silicone
7 scientific references
  • FDA Code of Federal Regulations, April 2020, ePublication
  • International Journal of Toxicology, May 2014, pages 65S-115S
  • The Journal of Clinical and Aesthetic Dermatology, May 2014, pages 36-44
  • Dermatologic Therapy, May 2012, pages 229-233
  • Clinics in Dermatology, May-June 2012, pages 345-348
  • International Journal of Cosmetic Science, January 2008, pages 19-33
  • Skin Research and Technology, May 2000, pages 77-80
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Solvent

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1-Decene, homopolymer, hydrogenated

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Siloxanes and Silicones, dodecyl methyl, 2-trimethylsilylpoly(oxydimethylsilyl)ethyl methyl, dimethyl

Silicone
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Deoxyribonucleic acid, sodium salts

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dimethicone/Vinyl Dimethicone Crosspolymer is a crosslinked dimethyl siloxane polymer (silicone elastomer) that is formed by the reaction between Hydrogen Dimethicone or Bis-Hydrogen Dimethicone, and Vinyl Dimethicone or Bis-Vinyldimethicone.

Silicone
22 Butylene Glycol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Texture agent, Solvent

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
23 Parfum Fragrance / colour
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Fragrance / colour

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Parfum is a term for ingredient labelling used to identify that a product contains a material or a combination of materials normally added to a cosmetic to produce or to mask a particular odour. According to Article 19 of the Cosmetics Regulation, 'Perfume and aromatic compositions and their raw materials shall be referred to by the terms ‘parfum’ or ‘aroma’. '

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
25 Trideceth-6 Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Poly(oxy-1,2-ethanediyl), .alpha.-tridecyl-.omega.-hydroxy; Isotridecanol, ethoxylated

26 Disodium Edta Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Chelator

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Disodium dihydrogen ethylenediaminetetraacetate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
28 Panthenol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Dihydroxypentane

Hydration
4 scientific references
  • https://thedermreviewcom/pentylene-glycol/
  • Regulatory Toxicology and Pharmacology, July 2017, pages 106-111
  • Prospector, June 2015, ePublication
  • International Journal of Toxicology, October 2012, pages 147S-168S
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydrolyzed Sodium DNA is the hydrolysate of Sodium DNA derived by acid, enzyme or other method of hydrolysis.

31 Hyaluronic Acid Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid

Anti-Aging Hydration
5 scientific references
  • Journal of Evidence-Based, Complementary and Alternative Medicine, October 2017, pages 816-823
  • Journal of Medicinal Food, October 2016, pages 1, 172-1, 179
  • Nutrition Journal, July 2013, ePublication
  • Journal of Drugs in Dermatology, 2011, issue 9, pages 990-1000
  • Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38-43
32 Tripeptide-1 Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Active, Peptide

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Tripeptide-1 is a synthetic peptide containing glycine, histidine, and lysine

Anti-Aging
33 Tocopherol Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E

Anti-Aging Evens Skin Tone Soothing
4 scientific references
  • Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
  • Journal of Investigative Dermatology, November 2001, pages 1212-1217
  • Canadian Family Physician, July 2006, pages 855-856
  • Dermatologic Surgery, April 1999, pages 311-315
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,4-(1H,3H)-Pyrimidinedione

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,4-(1H,3H)-Pyrimidinedione, 5-methyl-

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1H-Purine-6-amine

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing, Surfactant, Plant extract

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae

Soothing Anti-Aging
6 scientific references
  • Phytomedicine, April 2018, pages 110–119
  • Clinical, Cosmetic, and Investigational Dermatology, August 2017, pages 311–315
  • Indian Journal of Pharmaceutical Sciences, Jan-Feb 2016, pages 27–33
  • Postepy Dermatologii I, February 2013, pages 46–49
  • Indian Journal of Pharmaceutical Sciences, 2010, pages 546–556
  • Scientific Reports, June 2021, ePublication
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, hydrogenated

Hydration
4 scientific references
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Nanocosmetics, June 2019, pages 95–140
  • Current Drug Delivery, 2016, pages 111–120
  • Pharmaceutical Research, February 2013, pages 538–55
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Portulaca Oleracea Extract is an extract of the whole plant of the Purselane, Portulaca oleracea L., Portulacaceae

Anti-Aging Soothing Hydration
6 scientific references
  • Food Chemistry, August 2019, pages 239-245
  • Journal of Pharmacopuncture, March 2019, pages 7-15
  • Antioxidants, August 2017, pages 1-9
  • American Journal of Translational Research, May 2016, pages 2, 138-2, 148
  • BioMed Research International, January 2015, pages 1-11
  • Journal of Ethnopharmacology, July 2001, pages 171–176; and December 2000, pages 445-451
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active, Peptide

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues

Anti-Aging Hydration
6 scientific references
  • Cosmetics, November 2020, Issue 7, Volume 4, page 91
  • La Clinica Terapeutica, November 2020, pages e539-e548
  • https://wwwcir-safetyorg/sites/default/files/AcetylHexapeptide-8pdf
  • Cutaneous and Ocular Toxicology, March 2015, pages 46-52
  • European Journal of Pharmaceutical Sciences, February 2015, pages 27-35
  • Dermatologic Therapy, September-October 2007, issue 5, pages 343-349
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Chamomilla Recutita Flower Extract is an extract of the flowerheads of the matricaria, Chamomilla recutita (L.), Compositae

Anti-Aging Soothing
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Vitex Agnus-Castus Extract is the extract of the berries of Vitex agnus-castus, Lamiaceae.

43 Guanine Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Guanine (CI 75170)

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

4-Amino-2(1H)-pyrimidinone

45 Ceramide NP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Hydration Anti-Aging
11 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271

People also compare

Products in the same category that share this formula's distinguishing ingredients.

PDRN Capsule Cream 100

VT Cosmetics

Shares 12 key ingredients with PDRN Rejuvenating Cream: Water, Glycerin, Niacinamide, Panthenol, Glyceryl Glucoside

Vita Toning Capsule Cream

d'Alba

Shares 11 key ingredients with PDRN Rejuvenating Cream: Glycerin, Niacinamide, Glyceryl Stearate, Cetearyl Alcohol, Sodium Polyacrylate

Lifting Peptide Eye Cream

Centellian24

Shares 10 key ingredients with PDRN Rejuvenating Cream: Water, Glycerin, Niacinamide, Phenyl Trimethicone, Cetearyl Alcohol

Madeca Cream Time Reverse

Centellian24

Shares 10 key ingredients with PDRN Rejuvenating Cream: Water, Glycerin, Glyceryl Stearate, Niacinamide, Sodium Hyaluronate

Frequently asked questions

What ingredients are in PDRN Rejuvenating Cream?

WATER, DIPROPYLENE GLYCOL, GLYCERIN, PHENYL TRIMETHICONE, OENOTHERA BIENNIS OIL, CETEARYL ALCOHOL, GLYCERYL GLUCOSIDE, NIACINAMIDE, CERA ALBA, PEG-100 STEARATE, ARGININE, HYDROXYACETOPHENONE, 1,2-HEXANEDIOL, GLYCERYL STEARATE, SODIUM POLYACRYLATE, CARBOMER, DIMETHICONE, HYDROGENATED POLYDECENE, LAURYL PEG-9 POLYDIMETHYLSILOXYETHYL DIMETHICONE, SODIUM DNA, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, BUTYLENE GLYCOL, PARFUM, ADENOSINE, TRIDECETH-6, DISODIUM EDTA, SODIUM HYALURONATE, PANTHENOL, PENTYLENE GLYCOL, HYDROLYZED SODIUM DNA, HYALURONIC ACID, TRIPEPTIDE-1, TOCOPHEROL, URACIL, THYMINE, ADENINE, CENTELLA ASIATICA EXTRACT, HYDROGENATED LECITHIN, PORTULACA OLERACEA EXTRACT, ACETYL HEXAPEPTIDE-8, CHAMOMILLA RECUTITA FLOWER EXTRACT, VITEX AGNUS-CASTUS EXTRACT, GUANINE, CYTOSINE, CERAMIDE NP.

What are the active ingredients in PDRN Rejuvenating Cream?

NIACINAMIDE, SODIUM HYALURONATE, PANTHENOL, HYALURONIC ACID, TRIPEPTIDE-1, ACETYL HEXAPEPTIDE-8, CERAMIDE NP.

How do I use PDRN Rejuvenating Cream?

Apply an appropriate amount to clean skin. Gently spread over the skin until absorbed. Use in the morning and evening.

What skin types is PDRN Rejuvenating Cream good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is PDRN Rejuvenating Cream good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is PDRN Rejuvenating Cream fungal acne safe?

2 ingredients could feed malassezia: Peg-100 Stearate, Glyceryl Stearate. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use PDRN Rejuvenating Cream while pregnant?

Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.

Is PDRN Rejuvenating Cream fragrance free?

No — it contains Parfum.

Does PDRN Rejuvenating Cream contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is PDRN Rejuvenating Cream silicone free?

No — it contains Phenyl Trimethicone, Dimethicone, Lauryl Peg-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/vinyl Dimethicone Crosspolymer.

Does PDRN Rejuvenating Cream contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is PDRN Rejuvenating Cream paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with PDRN Rejuvenating Cream?

It layers well with Vitamin C (L-ascorbic acid), Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide.

When should I apply PDRN Rejuvenating Cream?

Use it morning and evening, after serums.

How many ingredients does PDRN Rejuvenating Cream have?

It lists 45 ingredients, of which 7 are recorded as actives.

Who makes PDRN Rejuvenating Cream?

Genabelle.

Brand
Genabelle

Reviews

0 total

Log in to leave a review.

No reviews yet. Be the first to share your thoughts.