NEOGEN Real Heartleaf Soothing Cream

NEOGEN

Real Heartleaf Soothing Cream

face cream

Added Last edited

Fit by skin type

General, ingredient-based — not your personalized match.

Dry
53%
Combination (dry)
53%
Balanced
83%
Combination (oily)
87%
Oily
87%

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Concentrations

HOUTTUYNIA CORDATA WATER 75%
43
Ingredients
4
Benefits
3
Actives
Find Dupes

Formulated with 75% Heartleaf ingredients, this lightweight gel cream swiftly infuses your skin with much-needed moisture, leaving you with a hydrated and supple complexion. Enriched with powerful ingredients such as Houttuynia Cordata Water, Panthenol, Arginine, Guaiazulene, and Macadamia Integrifolia Seed Oil, this cream provides soothing relief and nourishment to your skin, combating dryness and restoring its natural radiance.

Key Insights

Benefits

4
Anti-Aging
Hydration
Pore Minimizer
Soothing

Active Ingredients

3
Hyaluronic acid Vitamin B3 (niacinamide) Vitamin B5 (panthenol)

Risks

2
Silicone
Synthetic polymer

Full Ingredients

43 total
HOUTTUYNIA CORDATA WATER (75%) GLYCERIN PROPANEDIOL BUTYLENE GLYCOL 1,2-HEXANEDIOL NIACINAMIDE Vitamin B3 (niacinamide) METHYL TRIMETHICONE CETYL ETHYLHEXANOATE OLEA EUROPAEA FRUIT OIL PANTHENOL Vitamin B5 (panthenol) ARGININE CETEARYL OLIVATE ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER CETYL ALCOHOL STEARYL ALCOHOL SORBITAN OLIVATE CARBOMER BETAINE ETHYLHEXYLGLYCERIN ADENOSINE DISODIUM EDTA PYRUS COMMUNIS FRUIT EXTRACT HEDERA HELIX LEAF/STEM EXTRACT PYRUS MALUS FRUIT EXTRACT FRAGARIA CHILOENSIS FRUIT EXTRACT WATER GUAIAZULENE MACADAMIA INTEGRIFOLIA SEED OIL CENTELLA ASIATICA EXTRACT XANTHAN GUM CALENDULA OFFICINALIS EXTRACT ARTEMISIA CAPILLARIS EXTRACT CAPRYLYL GLYCOL GLUCOSE SODIUM HYALURONATE Hyaluronic acid CHONDRUS CRISPUS EXTRACT HYDROXYPROPYLTRIMONIUM HYALURONATE HYDROLYZED HYALURONIC ACID Hyaluronic acid SODIUM ACETYLATED HYALURONATE Hyaluronic acid HYALURONIC ACID Hyaluronic acid SODIUM HYALURONATE CROSSPOLYMER Hyaluronic acid HYDROLYZED SODIUM HYALURONATE POTASSIUM HYALURONATE Hyaluronic acid

About Real Heartleaf Soothing Cream

Overview

Real Heartleaf Soothing Cream is a lightweight cream from NEOGEN. The formula is built mainly around hydration. The ingredient list runs to 43 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. It contains both silicones and oils, a combination that usually finishes smooth and slightly satin and sits well under makeup. Hydration is handled by Glycerin, Propanediol and Butylene Glycol, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: Very high. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Propanediol, Butylene Glycol and Panthenol.

Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Cetyl Ethylhexanoate, Panthenol, Centella Asiatica Extract and Calendula Officinalis Extract.

Who it suits

On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on antioxidant protection, cell renewal and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after serums. Seal in your serums with it; in the morning, sunscreen still goes on top.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • 4 ingredients could feed malassezia (fungal acne)

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin
  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 21 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 10 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 6 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

Does not target

Anti-Acne Blackhead Reducing Dark Spot Fading Evens Skin Tone Oil Control Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

Glycerin

2nd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
Propanediol

3rd on the list, which puts it at an estimated 5–20% of the formula.

1,3-dihydroxypropane

Hydration
Butylene Glycol

4th on the list, which puts it at an estimated 2–10% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
Niacinamide Vitamin B3 (niacinamide)

6th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
Methyl Trimethicone

7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,1,3,5,5,5-Heptamethyl-3-(trimethylsilyloxy)trisiloxane

Hydration
Cetyl Ethylhexanoate

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hexadecyl 2-ethylhexanoate

Hydration
Olea Europaea Fruit Oil

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Olea Europaea Fruit Oil is the fixed oil obtained from the ripe fruit of the Olive, Olea europaea L., Oleaceae. It consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic

Hydration Anti-Aging
Panthenol Vitamin B5 (panthenol)

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
Arginine

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

L-Arginine

Hydration Anti-Aging
Cetearyl Olivate

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cetearyl Olivate is the ester of Cetearyl Alcohol and the fatty acids derived from olive oil

Hydration
Cetyl Alcohol

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hexadecan-1-ol

Hydration
Betaine

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt

Hydration

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration Very high

Ingredients that pull and hold water in the upper layers of skin

Barrier support Low

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control Low

Ingredients that moderate sebum or absorb shine

Brightening Low

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Moderate

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Supporting ingredients (35)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Houttuynia Cordata Water Glycerin Propanediol Butylene Glycol 1,2-hexanediol Methyl Trimethicone Cetyl Ethylhexanoate Olea Europaea Fruit Oil Arginine Cetearyl Olivate Acrylates/c10-30 Alkyl Acrylate Crosspolymer Cetyl Alcohol Stearyl Alcohol Sorbitan Olivate Carbomer Betaine Ethylhexylglycerin Adenosine Disodium Edta Pyrus Communis Fruit Extract Hedera Helix Leaf/stem Extract Pyrus Malus Fruit Extract Fragaria Chiloensis Fruit Extract Water Guaiazulene Macadamia Integrifolia Seed Oil Centella Asiatica Extract Xanthan Gum Calendula Officinalis Extract Artemisia Capillaris Extract Caprylyl Glycol Glucose Chondrus Crispus Extract Hydroxypropyltrimonium Hyaluronate Hydrolyzed Sodium Hyaluronate

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • No animal-derived ingredients

Contains

  • Silicones

    Methyl Trimethicone

  • Facial oils

    Olea Europaea Fruit Oil, Macadamia Integrifolia Seed Oil

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Vitamin C (L-ascorbic acid)
  • Retinoids (retinol, retinal)
  • AHAs (glycolic, lactic)
  • BHA (salicylic acid)
  • PHAs (gluconolactone)
  • Benzoyl peroxide
  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Nothing in this formula belongs to a group our rules can put in conflict, so it layers freely. Order still matters — thinnest texture first.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Moisturise" step.

  • Seal in your serums with it; in the morning, sunscreen still goes on top.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Nothing in this formula is on the standard pregnancy-caution list. That is not clearance — ask your doctor about anything you use daily.
Fungal acne (malassezia)
4 ingredients could feed malassezia: Olea Europaea Fruit Oil, Cetearyl Olivate, Sorbitan Olivate, Macadamia Integrifolia Seed Oil. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 43 ingredients on the label.

11
Texture agent

Sets the thickness, spread and stability of the formula

9
Humectant

Draws water into the upper layers of skin

8
Active

Changes how skin behaves rather than how it feels

8
Plant extract

Botanical material, usually for antioxidants or scent

6
Solvent

Dissolves and carries everything else

5
Surfactant

Lifts oil and dirt, or holds oil and water together

4
Emollient

Softens and smooths by filling gaps between skin cells

4
Occlusive

Forms a film that slows water loss

2
Soothing

Calms visible redness and irritation

2
Preservative

Keeps the product free of microbial growth

1
Chelator

Binds trace metals that would otherwise spoil the formula

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Houttuynia Cordata Water
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line

1st on the list, which puts it at an estimated 30–80% of the formula.

Houttuynia Cordata Water is the aqueous solution of the steam distillate of the whole plant, Houttuynia cordata, Saururaceae.

2 Glycerin Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
3 Propanediol Texture agent
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

1,3-dihydroxypropane

Hydration
4 scientific references
  • PubChem Compound Summary, April 2021, ePublication
  • SpecialChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Cosmetics & Toiletries, May 2013, pages 81-86
4 Butylene Glycol Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

4th on the list, which puts it at an estimated 2–10% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
5 1,2-hexanediol Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

5th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6 Niacinamide Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

6th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
7 Methyl Trimethicone Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,1,3,5,5,5-Heptamethyl-3-(trimethylsilyloxy)trisiloxane

Hydration Silicone
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
8 Cetyl Ethylhexanoate Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hexadecyl 2-ethylhexanoate

Hydration
2 scientific references
  • Engineering in Life Sciences, March 2019, pages 370-388
  • International Journal of Toxicology, Nov-Dec 2015, pages 61S-73S
9 Olea Europaea Fruit Oil
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Olea Europaea Fruit Oil is the fixed oil obtained from the ripe fruit of the Olive, Olea europaea L., Oleaceae. It consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic

Hydration Anti-Aging
10 Panthenol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
11 Arginine
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

L-Arginine

Hydration Anti-Aging
6 scientific references
  • Biobased Surfactants (Second Edition), 2019, pages 413-445
  • Scientific Reports, February 2016, pages 1-10
  • Cosmetic Ingredient Review, October 2012, pages 1-35
  • Journal of Advanced Research, July 2010, pages 169–177
  • International Journal of Cosmetic Science, April 2005, page 139
  • Wound Repair and Regeneration, November-December 2003, pages 419-423
12 Cetearyl Olivate
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cetearyl Olivate is the ester of Cetearyl Alcohol and the fatty acids derived from olive oil

Hydration
13 Acrylates/c10-30 Alkyl Acrylate Crosspolymer Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol

Synthetic polymer
14 Cetyl Alcohol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant, Texture agent

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hexadecan-1-ol

Hydration
3 scientific references
  • International Journal of Cosmetic Science, December 2012, Issue 34, Volume 6, pages 567-74
  • http://wwwcir-safetyorg/sites/default/files/115_buff3a_supplpdf
  • https://pubchemncbinlmnihgov/compound/1-Hexadecanol
15 Stearyl Alcohol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant, Texture agent

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Octadecan-1-ol

16 Sorbitan Olivate Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

D-Glucitol, 1,4-Anhydro-, 6-monoester with olive oil fatty acids

17 Carbomer Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether

Synthetic polymer
18 Betaine Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Texture agent

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt

Hydration
5 scientific references
  • International Journal of Toxicology, 2018, pages 28S-46S
  • Food Science and Biotechnology, October 2017, pages 1391-1397
  • The Journal of Chemical Physics, June 2015, ePublication
  • The American Journal of Clinical Nutrition, September 2004, pages 539-549
  • Skin Research and Technology, February 2003, pages 50-58
19 Ethylhexylglycerin
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
20 Adenosine
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
21 Disodium Edta Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Chelator

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Disodium dihydrogen ethylenediaminetetraacetate

22 Pyrus Communis Fruit Extract Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Plant extract

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Pyrus Communis Fruit Extract is an extract of the fruit of the Pear, Pyrus communis L., Rosaceae

23 Hedera Helix Leaf/stem Extract Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing, Plant extract, Preservative

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hedera Helix Leaf/Stem Extract is an extract of the leaves and stems of the Ivy, Hedera helix L., Araliaceae

24 Pyrus Malus Fruit Extract Plant extract
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Pyrus Malus Fruit Extract is an extract of the fruit of the Apple, Pyrus malus L., Rosaceae

Anti-Aging Hydration
25 Fragaria Chiloensis Fruit Extract Plant extract
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Fragaria Chiloensis Fruit Extract is an extract of the fruit of the Strawberry, Fragaria chiloensis, Rosaceae

26 Water Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
27 Guaiazulene Preservative
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Preservative

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

7-Isopropyl-1,4-dimethylazulene

28 Macadamia Integrifolia Seed Oil
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Macadamia Integrifolia Seed Oil is the fixed oil obtained from the nuts of the Macadamia integrifolia, Proteaceae

29 Centella Asiatica Extract Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing, Surfactant, Plant extract

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae

Soothing Anti-Aging
6 scientific references
  • Phytomedicine, April 2018, pages 110–119
  • Clinical, Cosmetic, and Investigational Dermatology, August 2017, pages 311–315
  • Indian Journal of Pharmaceutical Sciences, Jan-Feb 2016, pages 27–33
  • Postepy Dermatologii I, February 2013, pages 46–49
  • Indian Journal of Pharmaceutical Sciences, 2010, pages 546–556
  • Scientific Reports, June 2021, ePublication
30 Xanthan Gum Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant, Texture agent

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Xanthan gum

31 Calendula Officinalis Extract Plant extract
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Calendula Officinalis Extract is the extract of the whole plant of the Calendula, Calendula officinalis L., Compositae

32 Artemisia Capillaris Extract Plant extract
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Artemisia Capillaris Extract is the extract of the whole plant Artemisia capillaris, Asteraceae.

33 Caprylyl Glycol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Octane-1,2-diol

34 Glucose Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glucose

Hydration
4 scientific references
  • International Journal of Molecular Sciences, March 2020, pages 1–13
  • Foods, March 2019, pages 1–27
  • Nature Medicine, May 2018, pages 617–627
  • Clinical Chemistry and Laboratory Medicine, September 2003, pages 1, 224–1, 228
35 Sodium Hyaluronate Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
36 Chondrus Crispus Extract Plant extract
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract, Texture agent

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Chondrus Crispus Extract is an extract of the carrageenan, Chondrus crispus, Gigartinaceae

37 Hydroxypropyltrimonium Hyaluronate Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, 2-hydroxy-3-(N,N,N-trimethylammonio)propyl chloride derivatives

38 Hydrolyzed Hyaluronic Acid Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis

Hydration
39 Sodium Acetylated Hyaluronate Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium Acetylhyaluronate

Hydration Anti-Aging
40 Hyaluronic Acid Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid

Anti-Aging Hydration
5 scientific references
  • Journal of Evidence-Based, Complementary and Alternative Medicine, October 2017, pages 816-823
  • Journal of Medicinal Food, October 2016, pages 1, 172-1, 179
  • Nutrition Journal, July 2013, ePublication
  • Journal of Drugs in Dermatology, 2011, issue 9, pages 990-1000
  • Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38-43
41 Sodium Hyaluronate Crosspolymer Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium salt, polymer with 1,1'-sulfonylbis[ethene]

Hydration Anti-Aging Soothing
42 Hydrolyzed Sodium Hyaluronate
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydrolyzed Sodium Hyaluronate is the hydrolysate of Sodium Hyaluronate derived by acid, enzyme or other method of hydrolysis

Hydration
43 Potassium Hyaluronate Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, potassium salt

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Frequently asked questions

What ingredients are in Real Heartleaf Soothing Cream?

HOUTTUYNIA CORDATA WATER, GLYCERIN, PROPANEDIOL, BUTYLENE GLYCOL, 1,2-HEXANEDIOL, NIACINAMIDE, METHYL TRIMETHICONE, CETYL ETHYLHEXANOATE, OLEA EUROPAEA FRUIT OIL, PANTHENOL, ARGININE, CETEARYL OLIVATE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, CETYL ALCOHOL, STEARYL ALCOHOL, SORBITAN OLIVATE, CARBOMER, BETAINE, ETHYLHEXYLGLYCERIN, ADENOSINE, DISODIUM EDTA, PYRUS COMMUNIS FRUIT EXTRACT, HEDERA HELIX LEAF/STEM EXTRACT, PYRUS MALUS FRUIT EXTRACT, FRAGARIA CHILOENSIS FRUIT EXTRACT, WATER, GUAIAZULENE, MACADAMIA INTEGRIFOLIA SEED OIL, CENTELLA ASIATICA EXTRACT, XANTHAN GUM, CALENDULA OFFICINALIS EXTRACT, ARTEMISIA CAPILLARIS EXTRACT, CAPRYLYL GLYCOL, GLUCOSE, SODIUM HYALURONATE, CHONDRUS CRISPUS EXTRACT, HYDROXYPROPYLTRIMONIUM HYALURONATE, HYDROLYZED HYALURONIC ACID, SODIUM ACETYLATED HYALURONATE, HYALURONIC ACID, SODIUM HYALURONATE CROSSPOLYMER, HYDROLYZED SODIUM HYALURONATE, POTASSIUM HYALURONATE.

What are the active ingredients in Real Heartleaf Soothing Cream?

NIACINAMIDE, PANTHENOL, SODIUM HYALURONATE, HYDROLYZED HYALURONIC ACID, SODIUM ACETYLATED HYALURONATE, HYALURONIC ACID, SODIUM HYALURONATE CROSSPOLYMER, POTASSIUM HYALURONATE.

How do I use Real Heartleaf Soothing Cream?

After cleansing, toning and using treatment products, dispense the cream into the palm of the hand. Smooth or pat over skin, until fully absorbed. Follow with SPF during the day or use it as your last skincare step at night.

What skin types is Real Heartleaf Soothing Cream good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is Real Heartleaf Soothing Cream good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is Real Heartleaf Soothing Cream fungal acne safe?

4 ingredients could feed malassezia: Olea Europaea Fruit Oil, Cetearyl Olivate, Sorbitan Olivate, Macadamia Integrifolia Seed Oil. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use Real Heartleaf Soothing Cream while pregnant?

Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.

Is Real Heartleaf Soothing Cream fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does Real Heartleaf Soothing Cream contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is Real Heartleaf Soothing Cream silicone free?

No — it contains Methyl Trimethicone.

Does Real Heartleaf Soothing Cream contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is Real Heartleaf Soothing Cream paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with Real Heartleaf Soothing Cream?

It layers well with Vitamin C (L-ascorbic acid), Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide.

When should I apply Real Heartleaf Soothing Cream?

Use it morning and evening, after serums.

How many ingredients does Real Heartleaf Soothing Cream have?

It lists 43 ingredients, of which 8 are recorded as actives.

Who makes Real Heartleaf Soothing Cream?

NEOGEN.

Brand
NEOGEN

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