1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Dr. Reju-All
Advanced Retino-Mela Serum
face serum
Dr. Reju-All
face serum
Added Last edited
Fit by skin type
General, ingredient-based — not your personalized match.
See how this fits your skin
Take the skin test and I'll show you how suitable this product is for you.
Take the skin testThe Dr. Reju-All Advanced Retino-Mela Serum is a high-performance treatment designed to target hyperpigmentation, uneven skin tone, and early signs of aging. Formulated with a potent combination of retinoid and melanin-correcting ingredients, this serum helps accelerate cell turnover while reducing the appearance of dark spots and discoloration. Its lightweight, fast-absorbing texture delivers powerful results while remaining comfortable on the skin. Balanced with soothing and barrier-supporting ingredients, the Dr. Reju-All Advanced Retino-Mela Serum helps minimize irritation often associated with retinoids. With consistent use, it improves skin clarity, refines texture, and promotes a brighter, smoother, and more even complexion.
Advanced Retino-Mela Serum is a lightweight serum from Dr. Reju-All, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 38 ingredients, each broken down in full below.
By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Butylene Glycol, Glycerin and Betaine, humectants that pull water into the upper layers of skin rather than sealing it there.
Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Butylene Glycol, Glycerin, Betaine and Propanediol.
Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Squalane and Panthenol.
Brightening: Moderate. Ingredients that act on uneven tone and post-inflammatory marks, and here that comes from Niacinamide, Tranexamic Acid, Hydroxypinacolone Retinoate and Tocopherol.
Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Bisabolol, Panthenol, Hydroxypinacolone Retinoate and Beta-glucan.
On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.
The formula contributes little or nothing on antioxidant protection, cell renewal and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.
Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.
It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.
This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.
Drawn purely from the ingredient list
Scored on how rich or light the formula reads from its INCI order.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Based on the curated benefits documented for this product's ingredients.
Attracts and locks in moisture to keep skin plump and dewy
Boosts collagen and cell turnover to reduce fine lines and wrinkles
Calms redness, irritation, and inflammation for sensitive skin
Brightens and balances complexion for a more uniform appearance
Targets breakouts by reducing bacteria and unclogging pores
Fades hyperpigmentation and evens out dark spots over time
Tightens and refines the look of enlarged pores
None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.
The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
3rd on the list, which puts it at an estimated 5–20% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
4th on the list, which puts it at an estimated 2–10% of the formula.
2,6,10,15,19,23-Hexamethyltetracosane
5th on the list, which puts it at an estimated 2–10% of the formula.
Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-
6th on the list, which puts it at an estimated 2–10% of the formula.
1,1,1,3,5,5,5-Heptamethyl-3-(trimethylsilyloxy)trisiloxane
7th on the list, which puts it at an estimated 1–5% of the formula.
1,2-Dihydroxypentane
8th on the list, which puts it at an estimated 1–5% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
10th on the list, which puts it at an estimated 1–5% of the formula.
Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt
11th on the list, which puts it at an estimated 1–3% of the formula.
1,3-dihydroxypropane
14th on the list, which puts it at an estimated 1–3% of the formula.
(R*,R*)-.alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (theta,theta)-(+/-)-; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (S-(theta,theta))- (levomenol)
15th on the list, which puts it at an estimated 1–3% of the formula.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
Each axis is scored from the ingredients present and how high up the list they sit.
Ingredients that pull and hold water in the upper layers of skin
Lipids and repair signals that support skin barrier integrity
Ingredients that mop up free radicals from UV and pollution
Ingredients that moderate sebum or absorb shine
Ingredients that act on uneven tone and post-inflammatory marks
Ingredients aimed at visible redness and reactivity
Retinoids, acids and enzymes that speed surface turnover
Peptides and growth factors that signal for collagen support
"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.
Solvents, emollients, texture agents and preservatives — the formula that carries the actives.
Read from the full ingredient list. A brand's own claim may differ.
Methyl Trimethicone
Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
This product is the "Treat" step.
Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.
Most ingredients do more than one job, so these counts add up to more than the 38 ingredients on the label.
Sets the thickness, spread and stability of the formula
Dissolves and carries everything else
Lifts oil and dirt, or holds oil and water together
Softens and smooths by filling gaps between skin cells
Draws water into the upper layers of skin
Changes how skin behaves rather than how it feels
Botanical material, usually for antioxidants or scent
Neutralises free radicals from UV and pollution
Forms a film that slows water loss
Calms visible redness and irritation
Sets the acidity the formula needs to work
Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
3rd on the list, which puts it at an estimated 5–20% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
4th on the list, which puts it at an estimated 2–10% of the formula.
2,6,10,15,19,23-Hexamethyltetracosane
5th on the list, which puts it at an estimated 2–10% of the formula.
Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-
6th on the list, which puts it at an estimated 2–10% of the formula.
1,1,1,3,5,5,5-Heptamethyl-3-(trimethylsilyloxy)trisiloxane
7th on the list, which puts it at an estimated 1–5% of the formula.
1,2-Dihydroxypentane
8th on the list, which puts it at an estimated 1–5% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
9th on the list, which puts it at an estimated 1–5% of the formula.
Hydrogenated Ethylhexyl Olivate is a misture of esters produced by the reaction of ethylhexanol and Hydrogenated Olive Oil
10th on the list, which puts it at an estimated 1–5% of the formula.
Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt
11th on the list, which puts it at an estimated 1–3% of the formula.
1,3-dihydroxypropane
12th on the list, which puts it at an estimated 1–3% of the formula.
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
13th on the list, which puts it at an estimated 1–3% of the formula.
C14-22 Alcohols is a mixture of synthetic fatty alcohols with 14 to 22 carbons in the alkyl chain
14th on the list, which puts it at an estimated 1–3% of the formula.
(R*,R*)-.alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (theta,theta)-(+/-)-; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (S-(theta,theta))- (levomenol)
15th on the list, which puts it at an estimated 1–3% of the formula.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
16th on the list, which puts it at an estimated 1–3% of the formula.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
17th on the list, which puts it at an estimated 1–3% of the formula.
Cyclohexanol, 4-(1,1-dimethylethyl)-
18th on the list, which puts it at an estimated 1–3% of the formula.
Chondrus Crispus Extract is an extract of the carrageenan, Chondrus crispus, Gigartinaceae
19th on the list, which puts it at an estimated 1–3% of the formula.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium hydroxyethyl acrylate and acryloyldimethyl taurate monomers
20th on the list, which puts it at an estimated 1–3% of the formula.
Stearic acid, monoester with glycerol
21st on the list, which puts it at an estimated 1–3% of the formula.
Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- (100 mol EO average molar ratio)
22nd on the list, which puts it at an estimated 1–3% of the formula.
Olive oil, unsaponifiable fraction, hydrogenated
23rd on the list, which puts it at an estimated 1–3% of the formula.
Saccharum Officinarum Extract is an extract of the sugar cane, Saccharum officinarum L., Poaceae
24th on the list, which puts it at an estimated 1–3% of the formula.
C12-20 Alkyl Glucoside is the product obtained by the condensation of C12-20 alcohols with glucose
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Xanthan gum
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hexadecanoic acid
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Stearic acid
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sorbitan, isooctadecanoate
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Paeonia Suffruticosa Root Extract is an extract of the roots of the Chinese Peony, Paeonia suffruticosa, Ranunculaceae
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
beta-Glucan is a polysaccharide consisting of b(1-3) linked glucose chains carrying b(1-6) linked glucose sidechains
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
Products in the same category that share this formula's distinguishing ingredients.
Dr.Althea
Shares 11 key ingredients with Advanced Retino-Mela Serum: Niacinamide, Butylene Glycol, Water, Betaine, Tranexamic Acid
Dr. Althea
Shares 11 key ingredients with Advanced Retino-Mela Serum: Niacinamide, Butylene Glycol, Water, Betaine, Tranexamic Acid
Medicube
Shares 10 key ingredients with Advanced Retino-Mela Serum: Water, Butylene Glycol, Glycerin, Propanediol, Niacinamide
Arencia
Shares 10 key ingredients with Advanced Retino-Mela Serum: Water, Butylene Glycol, Glycerin, Propanediol, Niacinamide
Eqqualberry
Shares 10 key ingredients with Advanced Retino-Mela Serum: Water, Butylene Glycol, Glycerin, Niacinamide, Betaine
COSRX
Shares 9 key ingredients with Advanced Retino-Mela Serum: Water, Butylene Glycol, Pentylene Glycol, Glycerin, Niacinamide
WATER, BUTYLENE GLYCOL, NIACINAMIDE, SQUALANE, TRANEXAMIC ACID, METHYL TRIMETHICONE, PENTYLENE GLYCOL, GLYCERIN, HYDROGENATED ETHYLHEXYL OLIVATE, BETAINE, PROPANEDIOL, DIMETHYL ISOSORBIDE, C14-22 ALCOHOLS, BISABOLOL, PANTHENOL, TOCOPHERYL ACETATE, 4-T-BUTYLCYCLOHEXANOL, CHONDRUS CRISPUS EXTRACT, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, GLYCERYL STEARATE, PEG-100 STEARATE, HYDROGENATED OLIVE OIL UNSAPONIFIABLES, SACCHARUM OFFICINARUM EXTRACT, C12-20 ALKYL GLUCOSIDE, 1,2-HEXANEDIOL, CARBOMER, HYDROXYPINACOLONE RETINOATE, TROMETHAMINE, ETHYLHEXYLGLYCERIN, XANTHAN GUM, ADENOSINE, PALMITIC ACID, STEARIC ACID, SORBITAN ISOSTEARATE, SODIUM HYALURONATE, PAEONIA SUFFRUTICOSA ROOT EXTRACT, BETA-GLUCAN, TOCOPHEROL.
NIACINAMIDE, PANTHENOL, HYDROXYPINACOLONE RETINOATE, SODIUM HYALURONATE.
Apply a small amount to clean, dry skin in the evening after toner. Start 2–3 times per week and gradually increase frequency as tolerated. Follow with moisturizer. Always use sunscreen during the day.
Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
4 ingredients could feed malassezia: Hydrogenated Ethylhexyl Olivate, Glyceryl Stearate, Peg-100 Stearate, Sorbitan Isostearate. That describes the yeast's food supply, not a prediction that they will cause a breakout.
It contains Hydroxypinacolone Retinoate, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.
Yes. Reading the full ingredient list, this formula is fragrance-free.
No. Reading the full ingredient list, this formula is no drying alcohol.
No — it contains Methyl Trimethicone.
No. Reading the full ingredient list, this formula is essential-oil-free.
Yes. Reading the full ingredient list, this formula is paraben-free.
It layers well with Retinoids (retinol, retinal), Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides. Take more care combining it with AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide, Vitamin C (L-ascorbic acid), Azelaic acid — use them in separate routines or on alternate days.
Use it morning and evening, after toner, before moisturiser.
It lists 38 ingredients, of which 4 are recorded as actives.
Dr. Reju-All, a brand based in Korea.
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