1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Mary&May
Spicule Collagen PDRN Cream
face neck cream
Mary&May
face neck cream
Added Last edited
Fit by skin type
General, ingredient-based — not your personalized match.
See how this fits your skin
Take the skin test and I'll show you how suitable this product is for you.
Take the skin testThe Mary&May Spicule Collagen PDRN Cream is a firming and skin-repair moisturizer designed to improve elasticity, enhance hydration, and support overall skin regeneration. This advanced cream helps deliver active ingredients deeper into the skin while promoting a smoother, more resilient complexion. Its rich yet comfortable texture nourishes the skin while helping to improve firmness and reduce the appearance of fine lines. With continued use, the Mary&May Spicule Collagen PDRN Cream leaves the skin looking plumper, more lifted, and visibly revitalized.
Spicule Collagen PDRN Cream is a lightweight cream from Mary&May, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 48 ingredients, each broken down in full below.
By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. It contains both silicones and oils, a combination that usually finishes smooth and slightly satin and sits well under makeup. Hydration is handled by Methylpropanediol, Glycerin and Panthenol, humectants that pull water into the upper layers of skin rather than sealing it there.
Hydration: Very high. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Methylpropanediol, Glycerin, Panthenol and Ethylhexylglycerin.
Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Panthenol, Cetyl Ethylhexanoate, Allantoin and Niacinamide.
Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Panthenol, Cholesterol and Butyrospermum Parkii Butter.
On richness alone it suits Balanced skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.
The formula contributes little or nothing on antioxidant protection, cell renewal and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.
Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.
It can be used morning and evening. In a routine it goes after serums. Seal in your serums with it; in the morning, sunscreen still goes on top.
This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.
Drawn purely from the ingredient list
Scored on how rich or light the formula reads from its INCI order.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Based on the curated benefits documented for this product's ingredients.
Attracts and locks in moisture to keep skin plump and dewy
Boosts collagen and cell turnover to reduce fine lines and wrinkles
Calms redness, irritation, and inflammation for sensitive skin
Brightens and balances complexion for a more uniform appearance
Regulates sebum production to reduce shine and greasiness
Tightens and refines the look of enlarged pores
None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.
The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
2-Methyl-1,3-propanediol
3rd on the list, which puts it at an estimated 5–20% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
5th on the list, which puts it at an estimated 2–10% of the formula.
Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl
6th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
7th on the list, which puts it at an estimated 1–5% of the formula.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of ammonium acryloyldimethyltaurate and vinylpyrrolidone monomers
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Stearic acid, monoester with glycerol
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
L-Arginine
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagens, hydrolyzates. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of hoofs and horns composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin.
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hexadecyl 2-ethylhexanoate
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
Each axis is scored from the ingredients present and how high up the list they sit.
Ingredients that pull and hold water in the upper layers of skin
Lipids and repair signals that support skin barrier integrity
Ingredients that mop up free radicals from UV and pollution
Ingredients that moderate sebum or absorb shine
Ingredients that act on uneven tone and post-inflammatory marks
Ingredients aimed at visible redness and reactivity
Retinoids, acids and enzymes that speed surface turnover
Peptides and growth factors that signal for collagen support
"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.
Solvents, emollients, texture agents and preservatives — the formula that carries the actives.
Read from the full ingredient list. A brand's own claim may differ.
Polypropylsilsesquioxane, Vinyl Dimethicone
Macadamia Ternifolia Seed Oil
Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.
Nothing in this formula belongs to a group our rules can put in conflict, so it layers freely. Order still matters — thinnest texture first.
This product is the "Moisturise" step.
Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.
Most ingredients do more than one job, so these counts add up to more than the 48 ingredients on the label.
Sets the thickness, spread and stability of the formula
Lifts oil and dirt, or holds oil and water together
Softens and smooths by filling gaps between skin cells
Forms a film that slows water loss
Changes how skin behaves rather than how it feels
Draws water into the upper layers of skin
Dissolves and carries everything else
Neutralises free radicals from UV and pollution
Calms visible redness and irritation
Binds trace metals that would otherwise spoil the formula
Botanical material, usually for antioxidants or scent
Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
2-Methyl-1,3-propanediol
3rd on the list, which puts it at an estimated 5–20% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
4th on the list, which puts it at an estimated 2–10% of the formula.
5th on the list, which puts it at an estimated 2–10% of the formula.
Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl
6th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
7th on the list, which puts it at an estimated 1–5% of the formula.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
8th on the list, which puts it at an estimated 1–5% of the formula.
Polymer formed by hydrolysis and condensation of propyltrichlorosilane
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of ammonium acryloyldimethyltaurate and vinylpyrrolidone monomers
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
C14-22 Alcohols is a mixture of synthetic fatty alcohols with 14 to 22 carbons in the alkyl chain
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Stearic acid, monoester with glycerol
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
L-Arginine
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagens, hydrolyzates. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of hoofs and horns composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin.
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hexadecyl 2-ethylhexanoate
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Macadamia Ternifolia Seed Oil is the fixed oil obtained from the nuts of the Bushnut, Macadamia ternifolia, Proteaceae. It consists primarily of the glycerides of the fatty acids
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Silicones and siloxanes, dimethyl, ethenyl methyl, ethenyldimethylsilyl terminated
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
C12-20 Alkyl Glucoside is the product obtained by the condensation of C12-20 alcohols with glucose
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Urea, (2,5-dioxo-4-imidazolidinyl)-
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Brassica Campestris Sterols is a mixture of sterols obtained from the Cabbage, Brassica campestris L., Brassicaceae
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio)
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Dextrin
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate monomers
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cholest-5-en-3-ol (beta)-
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Sponge is the hydrolysate of sponge obtained by acid, enzyme or other method of hydrolysis
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Phytosteryl/Behenyl/Octyldodecyl/Isostearyl Lauroyl Glutamate is the mixed ester of Phytosterol, Behenyl Alcohol, Octyldodecanol and Isostearyl Alcohol with Lauroyl Glutamic Acid
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Xanthan gum
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Homopolymer of 2-methyl-1 propene
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Gardenia Florida Fruit Extract is an extract of the fruit of the Cape Jasmine, Gardenia Florida L., Rubiaceae
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Butyrospermum Parkii Butter is the fat obtained from the fruit of the Shea Tree, Butyrospernum parkii, Sapotaceae
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
D-Glucose homopolymer, dodecyl ether
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (6 mol glycerol average molar ratio)
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lecithins, hydrogenated
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Disodium dihydrogen ethylenediaminetetraacetate
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glyceryl Acrylate/Acrylic Acid Copolymer is a copolymer of glyceryl acrylate and acrylic acid
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tetradecyl D-glucopyranoside
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Polymer of glutamic acid
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
D-Glucopyranose, oligomers, decyl octyl glycosides
43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2,5-Furandione, polymer with methoxyethene; copolymer of methyl vinyl ether and maleic anhydride
44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine
45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Stearic acid
46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
9-Octadecenoic acid (9Z)-
47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sodium 3,8-dimethyl-5-(isopropyl)-1-azulenesulfonate
48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Deoxyribonucleic acid, sodium salts
Products in the same category that share this formula's distinguishing ingredients.
Dr. Ceuracle
Shares 12 key ingredients with Spicule Collagen PDRN Cream: Water, Cetyl Ethylhexanoate, Niacinamide, Caprylic/capric Triglyceride, Glycerin
VT Cosmetics
Shares 12 key ingredients with Spicule Collagen PDRN Cream: Water, Glycerin, Methylpropanediol, Cetyl Ethylhexanoate, Caprylic/capric Triglyceride
Abib
Shares 11 key ingredients with Spicule Collagen PDRN Cream: Water, Glycerin, Niacinamide, Caprylic/capric Triglyceride, Methylpropanediol
Medicube
Shares 11 key ingredients with Spicule Collagen PDRN Cream: Methylpropanediol, Glycerin, Caprylic/capric Triglyceride, Panthenol, Niacinamide
Centellian24
Shares 11 key ingredients with Spicule Collagen PDRN Cream: Water, Caprylic/capric Triglyceride, Glycerin, Glyceryl Stearate, Niacinamide
Numbuzin
Shares 11 key ingredients with Spicule Collagen PDRN Cream: Water, Glycerin, Cetyl Ethylhexanoate, Niacinamide, Methylpropanediol
WATER, METHYLPROPANEDIOL, GLYCERIN, 1,2-HEXANEDIOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, NIACINAMIDE, PANTHENOL, POLYPROPYLSILSESQUIOXANE, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, C14-22 ALCOHOLS, GLYCERYL STEARATE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, ARGININE, HYDROLYZED COLLAGEN, CETYL ETHYLHEXANOATE, MACADAMIA TERNIFOLIA SEED OIL, VINYL DIMETHICONE, C12-20 ALKYL GLUCOSIDE, TOCOPHEROL, ALLANTOIN, BRASSICA CAMPESTRIS STEROLS, POLYGLYCERYL-10 LAURATE, ETHYLHEXYLGLYCERIN, DEXTRIN, SODIUM ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, CHOLESTEROL, HYDROLYZED SPONGE, PHYTOSTERYL/BEHENYL/OCTYLDODECYL/ISOSTEARYL LAUROYL GLUTAMATE, XANTHAN GUM, POLYISOBUTENE, GARDENIA FLORIDA FRUIT EXTRACT, BUTYROSPERMUM PARKII BUTTER, ADENOSINE, LAURYL GLUCOSIDE, POLYGLYCERYL-6 LAURATE, HYDROGENATED LECITHIN, SODIUM HYALURONATE, DISODIUM EDTA, GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER, MYRISTYL GLUCOSIDE, POLYGLUTAMIC ACID, CAPRYLYL/CAPRYL GLUCOSIDE, PVM/MA COPOLYMER, CERAMIDE NP, STEARIC ACID, OLEIC ACID, SODIUM GUAIAZULENE SULFONATE, SODIUM DNA.
NIACINAMIDE, PANTHENOL, SODIUM HYALURONATE, CERAMIDE NP.
Apply an appropriate amount as the final step of your skincare routine. Gently massage into the face and neck until fully absorbed. Use morning and evening.
Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry) skin.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
5 ingredients could feed malassezia: Glyceryl Stearate, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Laurate, Butyrospermum Parkii Butter, Polyglyceryl-6 Laurate. That describes the yeast's food supply, not a prediction that they will cause a breakout.
Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.
Yes. Reading the full ingredient list, this formula is fragrance-free.
No. Reading the full ingredient list, this formula is no drying alcohol.
No — it contains Polypropylsilsesquioxane, Vinyl Dimethicone.
No. Reading the full ingredient list, this formula is essential-oil-free.
Yes. Reading the full ingredient list, this formula is paraben-free.
It layers well with Vitamin C (L-ascorbic acid), Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide.
Use it morning and evening, after serums.
It lists 48 ingredients, of which 4 are recorded as actives.
Mary&May, a brand based in Korea.
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