2nd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Medicube
Azelaic Acid Exosome Shot 2000
face serum
Medicube
face serum
Added Last edited
Fit by skin type
General, ingredient-based — not your personalized match.
See how this fits your skin
Take the skin test and I'll show you how suitable this product is for you.
Take the skin testMedicube Azelaic Acid Exosome Shot 2000 helps brighten, smooth, and visibly refine blemish-prone skin. It is a targeted treatment designed to improve the appearance of post-breakout marks, uneven skin tone, rough texture, and visible pores. It combines Azelaic Acid, Niacinamide, and Betaine Salicylate to help clarify and gently exfoliate the skin while supporting a brighter, more balanced complexion. The formula is enhanced with Hydrolyzed Sponge technology, Milk Exosomes, Lactobacillus Extracellular Vesicles, Centella Asiatica, Ceramide NP, Sodium Hyaluronate, and Collagen to support skin renewal, hydration, and barrier care.
Azelaic Acid Exosome Shot 2000 is a lightweight serum from Medicube, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 47 ingredients, each broken down in full below.
By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Butylene Glycol, Glycerin and Ethylhexylglycerin, humectants that pull water into the upper layers of skin rather than sealing it there.
Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Butylene Glycol, Glycerin, Ethylhexylglycerin and Betaine Salicylate.
Oil control: Moderate. Ingredients that moderate sebum or absorb shine, and here that comes from Niacinamide, Calcium Aluminum Borosilicate, Salicylic Acid and Sodium Polyacrylate.
Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Centella Asiatica Extract, Asiaticoside, Niacinamide and Adenosine.
Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Pantothenic Acid and Ceramide NP.
On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.
The formula contributes little or nothing on antioxidant protection and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.
Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.
It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.
This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.
Drawn purely from the ingredient list
Scored on how rich or light the formula reads from its INCI order.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Based on the curated benefits documented for this product's ingredients.
Boosts collagen and cell turnover to reduce fine lines and wrinkles
Attracts and locks in moisture to keep skin plump and dewy
Calms redness, irritation, and inflammation for sensitive skin
Targets breakouts by reducing bacteria and unclogging pores
Fades hyperpigmentation and evens out dark spots over time
Helps unclog pores and reduce blackheads for clearer skin
Regulates sebum production to reduce shine and greasiness
Tightens and refines the look of enlarged pores
Refines texture by gently exfoliating rough, uneven patches
None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.
The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.
2nd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
4th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
5th on the list, which puts it at an estimated 2–10% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
6th on the list, which puts it at an estimated 2–10% of the formula.
2-Propenoic acid, homopolymer, sodium salt
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cetearyl Olivate is the ester of Cetearyl Alcohol and the fatty acids derived from olive oil
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,1,5,5,5-Hexamethyl-3-phenyl-3-[(trimethylsilyl)oxy]trisiloxane
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Melia Azadirachta Leaf Extract is an extract of the leaves of the Neem Tree, Melia azadirachta L., Meliaceae
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Melia Azadirachta Flower Extract is an extract of the flowers of the Neem Tree, Melia Azadirachta L., Meliaceae
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Solanum Melogena Fruit Extract is an extract of the fruit of the Eggplant, Solanum melongena L., Solanaceae
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt
Each axis is scored from the ingredients present and how high up the list they sit.
Ingredients that pull and hold water in the upper layers of skin
Lipids and repair signals that support skin barrier integrity
Ingredients that mop up free radicals from UV and pollution
Ingredients that moderate sebum or absorb shine
Ingredients that act on uneven tone and post-inflammatory marks
Ingredients aimed at visible redness and reactivity
Retinoids, acids and enzymes that speed surface turnover
Peptides and growth factors that signal for collagen support
"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.
Solvents, emollients, texture agents and preservatives — the formula that carries the actives.
Read from the full ingredient list. A brand's own claim may differ.
Phenyl Trimethicone
Collagen
Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.
Best kept to separate routines — one in the morning, one at night, or on alternate days.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
Can be layered, but the combination raises the irritation risk. Go slowly.
This product is the "Treat" step.
Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.
Most ingredients do more than one job, so these counts add up to more than the 47 ingredients on the label.
Botanical material, usually for antioxidants or scent
Sets the thickness, spread and stability of the formula
Draws water into the upper layers of skin
Dissolves and carries everything else
Changes how skin behaves rather than how it feels
Softens and smooths by filling gaps between skin cells
Forms a film that slows water loss
Lifts oil and dirt, or holds oil and water together
Binds trace metals that would otherwise spoil the formula
Loosens or dissolves dead surface cells
Sets the acidity the formula needs to work
Keeps the product free of microbial growth
Neutralises free radicals from UV and pollution
Calms visible redness and irritation
Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.
1st on the list, which puts it at an estimated 30–80% of the formula.
Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
3rd on the list, which puts it at an estimated 5–20% of the formula.
1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol
4th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
5th on the list, which puts it at an estimated 2–10% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
6th on the list, which puts it at an estimated 2–10% of the formula.
2-Propenoic acid, homopolymer, sodium salt
7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octane-1,2-diol
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cetearyl Olivate is the ester of Cetearyl Alcohol and the fatty acids derived from olive oil
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,1,5,5,5-Hexamethyl-3-phenyl-3-[(trimethylsilyl)oxy]trisiloxane
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
D-Glucitol, 1,4-Anhydro-, 6-monoester with olive oil fatty acids
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Sponge is the hydrolysate of sponge obtained by acid, enzyme or other method of hydrolysis
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Melia Azadirachta Leaf Extract is an extract of the leaves of the Neem Tree, Melia azadirachta L., Meliaceae
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Melia Azadirachta Flower Extract is an extract of the flowers of the Neem Tree, Melia Azadirachta L., Meliaceae
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glyceryl Acrylate/Acrylic Acid Copolymer is a copolymer of glyceryl acrylate and acrylic acid
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Calcium Aluminium Borosilicate is a glass consisting essentially of calcium and aluminium borosilicates
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Coccinia Indica Fruit Extract is an extract of the fruit of Coccinia indica, Cucurbitaceae
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Disodium dihydrogen ethylenediaminetetraacetate
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2,5-Furandione, polymer with methoxyethene; copolymer of methyl vinyl ether and maleic anhydride
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ocimum Sanctum Leaf Extract is an extract of the leaves of Ocimum sanctum, Labiatae
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Aloe Barbadensis Flower Extract is an extract of the flowers of the aloe, Aloe barbadensis, Liliaceae
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Solanum Melogena Fruit Extract is an extract of the fruit of the Eggplant, Solanum melongena L., Solanaceae
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Nonanedioic acid
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Curcuma Longa Root Extract is an extract of the rhizomes of the Turmeric, Curcuma longa L., Zingiberaceae
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Corallina Officinalis Extract is an extract of the Alga, Corallina officinalis L., Corallinaceae
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lactobacillus Extracellular Vesicles are the extracellular vesicles released into and isolated from the growth media removed from cell cultures of the microorganism Lactobacillus.
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3-Methylbutane-1,2-diol
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Betaine Salycilate is the product formed by the reaction of Betaine with Salycilic Acid
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Hydroxy-1,2,3-propanetricarboxylic acid
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Propanoic acid, 3-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino-, (R)-
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Milk Exosomes
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-dihydroxypropane
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Triglycerol
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagens, hydrolyzates. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of hoofs and horns composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin.
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagens. A fibrous protein comprising one third of the total protein in mammalian organisms. It is a polypeptide containing three peptide chains and rich in proline and hydroxyproline
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester (2alpha, 3beta, 4alpha)-
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-
43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine
44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
(2.alpha.,3.beta.,4.alpha.)-2,3,23-Trihydroxyurs-12-en-28-oic acid
45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sorbitan stearate
46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hexadecanoic acid
47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Salicylic acid
Products in the same category that share this formula's distinguishing ingredients.
Medicube
Shares 13 key ingredients with Azelaic Acid Exosome Shot 2000: Niacinamide, Glycerin, Sodium Polyacrylate, Cetearyl Olivate, Melia Azadirachta Leaf Extract
Numbuzin
Shares 11 key ingredients with Azelaic Acid Exosome Shot 2000: Butylene Glycol, Niacinamide, Glycerin, Pantothenic Acid, Ethylhexylglycerin
Numbuzin
Shares 11 key ingredients with Azelaic Acid Exosome Shot 2000: Butylene Glycol, Glycerin, Niacinamide, Sodium Hyaluronate, Melia Azadirachta Leaf Extract
Eqqualberry
Shares 11 key ingredients with Azelaic Acid Exosome Shot 2000: Butylene Glycol, Niacinamide, Glycerin, Sodium Hyaluronate, Ceramide NP
Medicube
Shares 11 key ingredients with Azelaic Acid Exosome Shot 2000: Glycerin, Niacinamide, Butylene Glycol, Dipotassium Glycyrrhizate, Salicylic Acid
Eqqualberry
Shares 10 key ingredients with Azelaic Acid Exosome Shot 2000: Butylene Glycol, Glycerin, Niacinamide, Sodium Hyaluronate, Ceramide NP
AQUA, BUTYLENE GLYCOL, DIPROPYLENE GLYCOL, NIACINAMIDE, GLYCERIN, SODIUM POLYACRYLATE, 1,2-HEXANEDIOL, CAPRYLYL GLYCOL, CETEARYL OLIVATE, PHENYL TRIMETHICONE, SORBITAN OLIVATE, HYDROLYZED SPONGE, MELIA AZADIRACHTA LEAF EXTRACT, MELIA AZADIRACHTA FLOWER EXTRACT, GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER, ETHYLHEXYLGLYCERIN, CALCIUM ALUMINUM BOROSILICATE, COCCINIA INDICA FRUIT EXTRACT, ADENOSINE, DISODIUM EDTA, PVM/MA COPOLYMER, OCIMUM SANCTUM LEAF EXTRACT, ALOE BARBADENSIS FLOWER EXTRACT, SOLANUM MELONGENA FRUIT EXTRACT, DIPOTASSIUM GLYCYRRHIZATE, AZELAIC ACID, CURCUMA LONGA ROOT EXTRACT, CORALLINA OFFICINALIS EXTRACT, LACTOBACILLUS EXTRACELLULAR VESICLES, ISOPENTYLDIOL, BETAINE SALICYLATE, CITRIC ACID, PANTOTHENIC ACID, MILK EXOSOMES, PROPANEDIOL, POLYGLYCERIN-3, HYDROLYZED COLLAGEN, SODIUM HYALURONATE, COLLAGEN, CENTELLA ASIATICA EXTRACT, ASIATICOSIDE, MADECASSIC ACID, CERAMIDE NP, ASIATIC ACID, SORBITAN STEARATE, PALMITIC ACID, SALICYLIC ACID.
NIACINAMIDE, CITRIC ACID, PANTOTHENIC ACID, SODIUM HYALURONATE, CERAMIDE NP, SALICYLIC ACID.
After cleansing, apply Medicube Azelaic Exosome Shot 2000 as the first step in your skincare routine. If preferred, use it after a gentle, hydrating toner. Dispense a pea-sized amount and spread evenly over the face, avoiding the eye and lip areas. Gently pat and press the product into the skin until fully absorbed. Follow with your favorite moisturizer to lock in hydration and complete your routine.
Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
4 ingredients could feed malassezia: Cetearyl Olivate, Sorbitan Olivate, Lactobacillus Extracellular Vesicles, Sorbitan Stearate. That describes the yeast's food supply, not a prediction that they will cause a breakout.
It contains Salicylic Acid, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.
Yes. Reading the full ingredient list, this formula is fragrance-free.
No. Reading the full ingredient list, this formula is no drying alcohol.
No — it contains Phenyl Trimethicone.
No. Reading the full ingredient list, this formula is essential-oil-free.
Yes. Reading the full ingredient list, this formula is paraben-free.
It layers well with Azelaic acid, Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides. Take more care combining it with Retinoids (retinol, retinal), Vitamin C (L-ascorbic acid), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide — use them in separate routines or on alternate days.
Use it morning and evening, after toner, before moisturiser.
It lists 47 ingredients, of which 6 are recorded as actives.
Medicube, a brand based in Korea.
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