Medicube Azelaic Acid Exosome Shot 2000

Medicube

Azelaic Acid Exosome Shot 2000

face serum

Added Last edited

Fit by skin type

General, ingredient-based — not your personalized match.

Dry
54%
Combination (dry)
54%
Balanced
84%
Combination (oily)
86%
Oily
86%

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47
Ingredients
9
Benefits
6
Actives
Find Dupes

Medicube Azelaic Acid Exosome Shot 2000 helps brighten, smooth, and visibly refine blemish-prone skin. It is a targeted treatment designed to improve the appearance of post-breakout marks, uneven skin tone, rough texture, and visible pores. It combines Azelaic Acid, Niacinamide, and Betaine Salicylate to help clarify and gently exfoliate the skin while supporting a brighter, more balanced complexion. The formula is enhanced with Hydrolyzed Sponge technology, Milk Exosomes, Lactobacillus Extracellular Vesicles, Centella Asiatica, Ceramide NP, Sodium Hyaluronate, and Collagen to support skin renewal, hydration, and barrier care.

Key Insights

Benefits

9
Anti-Acne
Anti-Aging
Blackhead Reducing
Dark Spot Fading
Hydration
Oil Control
Pore Minimizer
Smooths Bumpy Skin
Soothing

Active Ingredients

6
AHA BHA Ceramides Hyaluronic acid Vitamin B3 (niacinamide) Vitamin B5 (panthenol)

Risks

2
Silicone
Synthetic polymer

About Azelaic Acid Exosome Shot 2000

Overview

Azelaic Acid Exosome Shot 2000 is a lightweight serum from Medicube, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 47 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Butylene Glycol, Glycerin and Ethylhexylglycerin, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Butylene Glycol, Glycerin, Ethylhexylglycerin and Betaine Salicylate.

Oil control: Moderate. Ingredients that moderate sebum or absorb shine, and here that comes from Niacinamide, Calcium Aluminum Borosilicate, Salicylic Acid and Sodium Polyacrylate.

Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Centella Asiatica Extract, Asiaticoside, Niacinamide and Adenosine.

Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Pantothenic Acid and Ceramide NP.

Who it suits

On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on antioxidant protection and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • 4 ingredients could feed malassezia (fungal acne)
  • Contains ingredients usually flagged for review during pregnancy

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin
  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Anti-Aging 13 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Hydration 12 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Soothing 8 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Anti-Acne 3 ingredients

    Targets breakouts by reducing bacteria and unclogging pores

  • Dark Spot Fading 2 ingredients

    Fades hyperpigmentation and evens out dark spots over time

  • Blackhead Reducing 1 ingredient

    Helps unclog pores and reduce blackheads for clearer skin

  • Oil Control 1 ingredient

    Regulates sebum production to reduce shine and greasiness

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

  • Smooths Bumpy Skin 1 ingredient

    Refines texture by gently exfoliating rough, uneven patches

Does not target

Evens Skin Tone

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

2nd on the list, which puts it at an estimated 5–20% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
Niacinamide Vitamin B3 (niacinamide)

4th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

5th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

6th on the list, which puts it at an estimated 2–10% of the formula.

2-Propenoic acid, homopolymer, sodium salt

Oil Control

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cetearyl Olivate is the ester of Cetearyl Alcohol and the fatty acids derived from olive oil

Hydration

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,5,5,5-Hexamethyl-3-phenyl-3-[(trimethylsilyl)oxy]trisiloxane

Hydration

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Melia Azadirachta Leaf Extract is an extract of the leaves of the Neem Tree, Melia azadirachta L., Meliaceae

Anti-Aging

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Melia Azadirachta Flower Extract is an extract of the flowers of the Neem Tree, Melia Azadirachta L., Meliaceae

Anti-Aging

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Solanum Melogena Fruit Extract is an extract of the fruit of the Eggplant, Solanum melongena L., Solanaceae

Anti-Aging

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt

Soothing Dark Spot Fading

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration High

Ingredients that pull and hold water in the upper layers of skin

Barrier support Moderate

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control Moderate

Ingredients that moderate sebum or absorb shine

Brightening Moderate

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Moderate

Ingredients aimed at visible redness and reactivity

Cell renewal Low

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (6)

Supporting ingredients (41)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Aqua Butylene Glycol Dipropylene Glycol Glycerin Sodium Polyacrylate 1,2-hexanediol Caprylyl Glycol Cetearyl Olivate Phenyl Trimethicone Sorbitan Olivate Hydrolyzed Sponge Melia Azadirachta Leaf Extract Melia Azadirachta Flower Extract Glyceryl Acrylate/acrylic Acid Copolymer Ethylhexylglycerin Calcium Aluminum Borosilicate Coccinia Indica Fruit Extract Adenosine Disodium Edta Pvm/ma Copolymer Ocimum Sanctum Leaf Extract Aloe Barbadensis Flower Extract Solanum Melongena Fruit Extract Dipotassium Glycyrrhizate Azelaic Acid Curcuma Longa Root Extract Corallina Officinalis Extract Lactobacillus Extracellular Vesicles Isopentyldiol Betaine Salicylate Milk Exosomes Propanediol Polyglycerin-3 Hydrolyzed Collagen Collagen Centella Asiatica Extract Asiaticoside Madecassic Acid Asiatic Acid Sorbitan Stearate Palmitic Acid

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • Oil-free

Contains

  • Silicones

    Phenyl Trimethicone

  • Animal-derived ingredients

    Collagen

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • Retinoids (retinol, retinal)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Vitamin C (L-ascorbic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • AHAs (glycolic, lactic)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • BHA (salicylic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • PHAs (gluconolactone)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • Benzoyl peroxide

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Treat" step.

  • Apply to clean, dry skin and give it a minute to absorb before the next layer.
  • Introduce one new treatment at a time so you can identify what is working.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Contains Salicylic Acid, usually reviewed with a doctor during pregnancy.
Fungal acne (malassezia)
4 ingredients could feed malassezia: Cetearyl Olivate, Sorbitan Olivate, Lactobacillus Extracellular Vesicles, Sorbitan Stearate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 47 ingredients on the label.

9
Plant extract

Botanical material, usually for antioxidants or scent

9
Texture agent

Sets the thickness, spread and stability of the formula

8
Humectant

Draws water into the upper layers of skin

7
Solvent

Dissolves and carries everything else

6
Active

Changes how skin behaves rather than how it feels

6
Emollient

Softens and smooths by filling gaps between skin cells

4
Occlusive

Forms a film that slows water loss

4
Surfactant

Lifts oil and dirt, or holds oil and water together

2
Chelator

Binds trace metals that would otherwise spoil the formula

2
Exfoliant

Loosens or dissolves dead surface cells

2
pH adjuster

Sets the acidity the formula needs to work

2
Preservative

Keeps the product free of microbial growth

1
Antioxidant

Neutralises free radicals from UV and pollution

1
Soothing

Calms visible redness and irritation

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Aqua Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Water

2 Butylene Glycol Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
3 Dipropylene Glycol Texture agent
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol

4 Niacinamide Active
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

4th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
5 Glycerin Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

5th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Occlusive, Texture agent

6th on the list, which puts it at an estimated 2–10% of the formula.

2-Propenoic acid, homopolymer, sodium salt

Oil Control Synthetic polymer
7 scientific references
  • International Food Research Journal, February 2021, pages 44 - 55
  • Journal of Nanoscience and Nanotechnology, March 2018, pages 1, 611-1, 614
  • Industrial & Engineering Chemistry Research, November 2014, pages 18, 346-18, 351
  • Journal of Applied Polymer Science, November 2001, pages 1, 515-1, 520
  • United States Patent, April 2000, ePublication
  • https://wwwsocochemcom/is-sodium-polyacrylate-safehtml
  • https://wwwcir-safetyorg/sites/default/files/acryco092018TARpdf
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

8 Caprylyl Glycol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Octane-1,2-diol

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cetearyl Olivate is the ester of Cetearyl Alcohol and the fatty acids derived from olive oil

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,5,5,5-Hexamethyl-3-phenyl-3-[(trimethylsilyl)oxy]trisiloxane

Hydration Silicone
5 scientific references
  • International Journal of Toxicology, 2006, pages 1-89
  • https://onlinepersonalcarecouncilorg/ctfa-static/online/lists/cir-pdfs/PRNS513pdf
  • Journal of Cosmetic Science, June 2003, pages 335-351
  • Silicone Surfactants, 1999, page 190
  • International Journal of Toxicology, 1986, pages 353-371
11 Sorbitan Olivate Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

D-Glucitol, 1,4-Anhydro-, 6-monoester with olive oil fatty acids

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydrolyzed Sponge is the hydrolysate of sponge obtained by acid, enzyme or other method of hydrolysis

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Melia Azadirachta Leaf Extract is an extract of the leaves of the Neem Tree, Melia azadirachta L., Meliaceae

Anti-Aging
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Melia Azadirachta Flower Extract is an extract of the flowers of the Neem Tree, Melia Azadirachta L., Meliaceae

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Texture agent

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glyceryl Acrylate/Acrylic Acid Copolymer is a copolymer of glyceryl acrylate and acrylic acid

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Calcium Aluminium Borosilicate is a glass consisting essentially of calcium and aluminium borosilicates

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Coccinia Indica Fruit Extract is an extract of the fruit of Coccinia indica, Cucurbitaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
20 Disodium Edta Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Chelator

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Disodium dihydrogen ethylenediaminetetraacetate

21 Pvm/ma Copolymer Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,5-Furandione, polymer with methoxyethene; copolymer of methyl vinyl ether and maleic anhydride

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ocimum Sanctum Leaf Extract is an extract of the leaves of Ocimum sanctum, Labiatae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Plant extract

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Aloe Barbadensis Flower Extract is an extract of the flowers of the aloe, Aloe barbadensis, Liliaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Solanum Melogena Fruit Extract is an extract of the fruit of the Eggplant, Solanum melongena L., Solanaceae

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt

Soothing Dark Spot Fading
8 scientific references
  • How to Care for Red, Sensitive Skin
  • 7 Best Products for Sensitive Skin
  • Skincare Tips for Calming Redness
  • Skin-Soothing Ingredients
  • How the Paula’s Choice CALM Collection Works
  • The Best Moisturizers for Sensitive Skin
  • The Best Ways to Treat Acne and Sensitive Skin
  • Skin Care for Extremely Dry, Sensitive Skin
26 Azelaic Acid pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Nonanedioic acid

Anti-Acne Dark Spot Fading Smooths Bumpy Skin
8 scientific references
  • Journal of Cosmetic Dermatology, March 2017, pages 35-42
  • The Journal of Clinical and Aesthetic Dermatology, March 2017, pages 37-40
  • Advanced Biomedical Research, February 2017, ePublication
  • Biomedicine & Pharmacotherapy, October 2016, pages 771-775
  • Skin Therapy Letter, January 2016, pages 1-7
  • Cutis, January 2016, pages E9-E11
  • Journal of Drugs in Dermatology, September 2015, pages 964-968
  • International Journal of Toxicology, August 2012, pages 1-72
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Curcuma Longa Root Extract is an extract of the rhizomes of the Turmeric, Curcuma longa L., Zingiberaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Corallina Officinalis Extract is an extract of the Alga, Corallina officinalis L., Corallinaceae

Hydration Anti-Aging
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lactobacillus Extracellular Vesicles are the extracellular vesicles released into and isolated from the growth media removed from cell cultures of the microorganism Lactobacillus.

30 Isopentyldiol Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3-Methylbutane-1,2-diol

Hydration
2 scientific references
  • UL Prospector, Accessed January 2022, ePublication
  • Cosmetic Ingredient Review, March 2018, pages 1-73
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Exfoliant, Preservative

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Betaine Salycilate is the product formed by the reaction of Betaine with Salycilic Acid

Anti-Acne
7 scientific references
  • Skin Purging vs Breakout – What Does Skin Purging Look Like?
  • What to Do When You Have Acne and Dry Skin
  • How to Minimize the Look of Post-Acne Marks
  • How to Manage Dehydrated, Oily, Acne-Prone Skin
  • Help for Breakouts on the Hairline and Scalp
  • The Best Ways to Treat Acne and Sensitive Skin
  • Say Goodbye to Body Acne
32 Citric Acid Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Chelator, pH adjuster

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Hydroxy-1,2,3-propanetricarboxylic acid

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Propanoic acid, 3-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino-, (R)-

Hydration Soothing
34 Milk Exosomes Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Milk Exosomes

35 Propanediol Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Solvent

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-dihydroxypropane

Hydration
4 scientific references
  • PubChem Compound Summary, April 2021, ePublication
  • SpecialChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Cosmetics & Toiletries, May 2013, pages 81-86
36 Polyglycerin-3 Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Triglycerol

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Emollient, Occlusive

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Collagens, hydrolyzates. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of hoofs and horns composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin.

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
39 Collagen Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Collagens. A fibrous protein comprising one third of the total protein in mammalian organisms. It is a polypeptide containing three peptide chains and rich in proline and hydroxyproline

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing, Surfactant, Plant extract

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae

Soothing Anti-Aging
6 scientific references
  • Phytomedicine, April 2018, pages 110–119
  • Clinical, Cosmetic, and Investigational Dermatology, August 2017, pages 311–315
  • Indian Journal of Pharmaceutical Sciences, Jan-Feb 2016, pages 27–33
  • Postepy Dermatologii I, February 2013, pages 46–49
  • Indian Journal of Pharmaceutical Sciences, 2010, pages 546–556
  • Scientific Reports, June 2021, ePublication
41 Asiaticoside Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester (2alpha, 3beta, 4alpha)-

Anti-Aging Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-

Anti-Aging Soothing
43 Ceramide NP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Hydration Anti-Aging
11 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

(2.alpha.,3.beta.,4.alpha.)-2,3,23-Trihydroxyurs-12-en-28-oic acid

Anti-Aging
45 Sorbitan Stearate Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sorbitan stearate

46 Palmitic Acid Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hexadecanoic acid

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Exfoliant, Preservative

47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Salicylic acid

Anti-Acne Anti-Aging Blackhead Reducing
10 scientific references
  • Experimental Dermatology, July 2019, pages 786-794
  • European Commission Scientific Committee on Consumer Safety, June 2019, pages 1-70
  • Regulatory Toxicology and Pharmacology, April 2018, pages 245-251
  • Journal of Cosmetic Science, January-February 2017, pages 55-58
  • Clinical, Cosmetic, and Investigational Dermatology, August 2015, pages 455-461
  • Clinical, Cosmetic, and Investigational Dermatology, November 2010, pages 135-142
  • Seminars in Cutaneous Medicine and Surgery, September 2008, pages 170-176
  • Journal of the American Academy of Dermatology, April 2007, pages 651-663
  • International Journal of Cosmetic Science, February 2000, pages 21-52
  • Seminars in Dermatology, December 1990, pages 305-308

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Frequently asked questions

What ingredients are in Azelaic Acid Exosome Shot 2000?

AQUA, BUTYLENE GLYCOL, DIPROPYLENE GLYCOL, NIACINAMIDE, GLYCERIN, SODIUM POLYACRYLATE, 1,2-HEXANEDIOL, CAPRYLYL GLYCOL, CETEARYL OLIVATE, PHENYL TRIMETHICONE, SORBITAN OLIVATE, HYDROLYZED SPONGE, MELIA AZADIRACHTA LEAF EXTRACT, MELIA AZADIRACHTA FLOWER EXTRACT, GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER, ETHYLHEXYLGLYCERIN, CALCIUM ALUMINUM BOROSILICATE, COCCINIA INDICA FRUIT EXTRACT, ADENOSINE, DISODIUM EDTA, PVM/MA COPOLYMER, OCIMUM SANCTUM LEAF EXTRACT, ALOE BARBADENSIS FLOWER EXTRACT, SOLANUM MELONGENA FRUIT EXTRACT, DIPOTASSIUM GLYCYRRHIZATE, AZELAIC ACID, CURCUMA LONGA ROOT EXTRACT, CORALLINA OFFICINALIS EXTRACT, LACTOBACILLUS EXTRACELLULAR VESICLES, ISOPENTYLDIOL, BETAINE SALICYLATE, CITRIC ACID, PANTOTHENIC ACID, MILK EXOSOMES, PROPANEDIOL, POLYGLYCERIN-3, HYDROLYZED COLLAGEN, SODIUM HYALURONATE, COLLAGEN, CENTELLA ASIATICA EXTRACT, ASIATICOSIDE, MADECASSIC ACID, CERAMIDE NP, ASIATIC ACID, SORBITAN STEARATE, PALMITIC ACID, SALICYLIC ACID.

What are the active ingredients in Azelaic Acid Exosome Shot 2000?

NIACINAMIDE, CITRIC ACID, PANTOTHENIC ACID, SODIUM HYALURONATE, CERAMIDE NP, SALICYLIC ACID.

How do I use Azelaic Acid Exosome Shot 2000?

After cleansing, apply Medicube Azelaic Exosome Shot 2000 as the first step in your skincare routine. If preferred, use it after a gentle, hydrating toner. Dispense a pea-sized amount and spread evenly over the face, avoiding the eye and lip areas. Gently pat and press the product into the skin until fully absorbed. Follow with your favorite moisturizer to lock in hydration and complete your routine.

What skin types is Azelaic Acid Exosome Shot 2000 good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is Azelaic Acid Exosome Shot 2000 good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is Azelaic Acid Exosome Shot 2000 fungal acne safe?

4 ingredients could feed malassezia: Cetearyl Olivate, Sorbitan Olivate, Lactobacillus Extracellular Vesicles, Sorbitan Stearate. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use Azelaic Acid Exosome Shot 2000 while pregnant?

It contains Salicylic Acid, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.

Is Azelaic Acid Exosome Shot 2000 fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does Azelaic Acid Exosome Shot 2000 contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is Azelaic Acid Exosome Shot 2000 silicone free?

No — it contains Phenyl Trimethicone.

Does Azelaic Acid Exosome Shot 2000 contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is Azelaic Acid Exosome Shot 2000 paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with Azelaic Acid Exosome Shot 2000?

It layers well with Azelaic acid, Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides. Take more care combining it with Retinoids (retinol, retinal), Vitamin C (L-ascorbic acid), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide — use them in separate routines or on alternate days.

When should I apply Azelaic Acid Exosome Shot 2000?

Use it morning and evening, after toner, before moisturiser.

How many ingredients does Azelaic Acid Exosome Shot 2000 have?

It lists 47 ingredients, of which 6 are recorded as actives.

Who makes Azelaic Acid Exosome Shot 2000?

Medicube, a brand based in Korea.

Brand
Medicube
Country
Korea

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