Medicube Red Serum 2.0

Medicube

Red Serum 2.0

face serum

Added Last edited

Fit by skin type

General, ingredient-based — not your personalized match.

Dry
56%
Combination (dry)
56%
Balanced
86%
Combination (oily)
84%
Oily
84%

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62
Ingredients
8
Benefits
4
Actives
Find Dupes

Red Serum 2.0 is a dermatologist-tested serum designed to target acne-prone and sensitive skin. Powered by niacinamide, centella asiatica extract, and patented skin-soothing complexes, this formula helps regulate excess sebum, minimize pores, and calm redness while enhancing skin barrier strength. The lightweight, fast-absorbing formula works to refine skin texture and restore balance, leaving a non-sticky finish.

Key Insights

Benefits

8
Anti-Acne
Anti-Aging
Blackhead Reducing
Dark Spot Fading
Evens Skin Tone
Hydration
Pore Minimizer
Soothing

Active Ingredients

4
BHA Ceramides Vitamin B3 (niacinamide) Vitamin B5 (panthenol)

Risks

3
Alcohol
Silicone
Synthetic polymer

About Red Serum 2.0

Overview

Red Serum 2.0 is a lightweight serum from Medicube, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 62 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Glycerin, Propanediol and Trehalose, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Propanediol, Trehalose and Betaine.

Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Allantoin, Panthenol, Centella Asiatica Leaf Extract and Xylitol.

Who it suits

On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on cell renewal and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, paraben-free, microplastic-free, sulfate-free, dye-free and oil-free. Those claims come from the ingredient list itself, not from the packaging. It does contain essential oils and drying alcohol, worth knowing if your skin reacts to any of them.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • Contains essential oils, a common source of reactivity
  • Contains drying alcohol high in the list
  • 2 ingredients could feed malassezia (fungal acne)
  • Contains ingredients usually flagged for review during pregnancy

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin
  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 19 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 13 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 8 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Anti-Acne 1 ingredient

    Targets breakouts by reducing bacteria and unclogging pores

  • Blackhead Reducing 1 ingredient

    Helps unclog pores and reduce blackheads for clearer skin

  • Dark Spot Fading 1 ingredient

    Fades hyperpigmentation and evens out dark spots over time

  • Evens Skin Tone 1 ingredient

    Brightens and balances complexion for a more uniform appearance

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

Does not target

Oil Control Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

3rd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

4th on the list, which puts it at an estimated 2–10% of the formula.

Xylitol

Hydration Soothing

6th on the list, which puts it at an estimated 2–10% of the formula.

1,3-dihydroxypropane

Hydration
Niacinamide Vitamin B3 (niacinamide)

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

alpha-D-Glucopyranoside, alpha-D-glucopyranosyl

Hydration

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt

Hydration

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Dihydroxypentane

Hydration

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of ammonium acryloyldimethyltaurate and vinylpyrrolidone monomers

Hydration

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt

Soothing Dark Spot Fading

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Salicylic acid

Anti-Acne Anti-Aging Blackhead Reducing

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration High

Ingredients that pull and hold water in the upper layers of skin

Barrier support Low

Lipids and repair signals that support skin barrier integrity

Antioxidant support Low

Ingredients that mop up free radicals from UV and pollution

Oil control Low

Ingredients that moderate sebum or absorb shine

Brightening Low

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Moderate

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (4)

Supporting ingredients (58)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Dipropylene Glycol Glycerin Xylitol Alcohol Denat. Propanediol 1,2-hexanediol Diethoxyethyl Succinate Trehalose Betaine Pentylene Glycol Butylene Glycol Sodium Acrylate/sodium Acryloyldimethyl Taurate Copolymer Sodium C12-14 Sec-pareth-8 Carboxylate Dimethicone Crosspolymer Polyisobutene Ammonium Acryloyldimethyltaurate/vp Copolymer Vinyl Dimethicone Tromethamine Dipotassium Glycyrrhizate Zinc PCA Carbomer Hydrogenated Lecithin Isododecane Allantoin Dimethyl Sulfone Polyquaternium-51 Caprylyl/capryl Glucoside Sorbitan Oleate 4-terpineol Melaleuca Alternifolia Leaf Oil Adenosine Xanthan Gum Ethylhexylglycerin Melia Azadirachta Leaf Extract Melia Azadirachta Flower Extract Caprylic/capric Triglyceride Coccinia Indica Fruit Extract Ocimum Sanctum Leaf Extract Aloe Barbadensis Flower Extract Solanum Melongena Fruit Extract Curcuma Longa Root Extract Corallina Officinalis Extract Sodium Stearoyl Glutamate Tocopherol Lactococcus Ferment Lysate Decyl Glucoside Camellia Sinensis Leaf Extract Centella Asiatica Leaf Extract Cladosiphon Okamuranus Extract Salix Alba Bark Extract Coffea Arabica Seed Extract Sodium Chloride Phenylpropanol Citrus Aurantium Bergamia Leaf Extract Levulinic Acid Sodium Levulinate Pinus Densiflora Leaf Extract

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • Oil-free
  • No animal-derived ingredients

Contains

  • Essential oils

    Melaleuca Alternifolia Leaf Oil

  • Drying alcohol

    Alcohol Denat.

  • Silicones

    Dimethicone Crosspolymer, Vinyl Dimethicone

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • Retinoids (retinol, retinal)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Vitamin C (L-ascorbic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • AHAs (glycolic, lactic)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • BHA (salicylic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • PHAs (gluconolactone)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • Benzoyl peroxide

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Treat" step.

  • Apply to clean, dry skin and give it a minute to absorb before the next layer.
  • Introduce one new treatment at a time so you can identify what is working.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Contains Salicylic Acid, usually reviewed with a doctor during pregnancy.
Fungal acne (malassezia)
2 ingredients could feed malassezia: Sorbitan Oleate, Melaleuca Alternifolia Leaf Oil. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Alcohol, Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 62 ingredients on the label.

16
Texture agent

Sets the thickness, spread and stability of the formula

15
Plant extract

Botanical material, usually for antioxidants or scent

12
Solvent

Dissolves and carries everything else

8
Humectant

Draws water into the upper layers of skin

7
Surfactant

Lifts oil and dirt, or holds oil and water together

6
Occlusive

Forms a film that slows water loss

4
Active

Changes how skin behaves rather than how it feels

4
Antioxidant

Neutralises free radicals from UV and pollution

4
Preservative

Keeps the product free of microbial growth

3
Emollient

Softens and smooths by filling gaps between skin cells

2
Soothing

Calms visible redness and irritation

1
Exfoliant

Loosens or dissolves dead surface cells

1
pH adjuster

Sets the acidity the formula needs to work

1
UV filter

Absorbs or scatters ultraviolet light

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Dipropylene Glycol Texture agent
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol

3 Glycerin Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
4 Xylitol Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant

4th on the list, which puts it at an estimated 2–10% of the formula.

Xylitol

Hydration Soothing
7 scientific references
  • Microorganisms, January 2021, pages 1–14
  • Clinical, Cosmetic, and Investigational Dermatology, May 2019, pages 323-331
  • Advances in Nutrition, January 2019, Supplement, pages S31-S48
  • Experimental Dermatology, March 2018, pages 280-284
  • International journal of Applied Pharmaceutical and Biological Research, 2017, pages 67-73
  • Acta-dermato venereological, February 2017, pages 182-187
  • https://wwwcir-safetyorg/sites/default/files/Mannitol, %20Sorbitol, %20Xylitol_0pdf
5 Alcohol Denat. Texture agent
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent, Preservative

5th on the list, which puts it at an estimated 2–10% of the formula.

Alcohol Denat. is ethyl alcohol that is denatured with one or more denaturing agents in accordance with the national legislation of each European Community (EU) country.

Alcohol
6 Propanediol Texture agent
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

6th on the list, which puts it at an estimated 2–10% of the formula.

1,3-dihydroxypropane

Hydration
4 scientific references
  • PubChem Compound Summary, April 2021, ePublication
  • SpecialChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Cosmetics & Toiletries, May 2013, pages 81-86
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

8 Niacinamide Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanedioic acid, bis(2-ethoxyethyl) ester

10 Trehalose Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

alpha-D-Glucopyranoside, alpha-D-glucopyranosyl

Hydration
7 scientific references
  • Cosmetics, October 2019, pages 1-10
  • Cell Death & Disease, July 2019, pages 1-16
  • International Journal of Toxicology, 2019, pages 5S-38S
  • Applied Microbiology and Biotechnology, February 2018, pages 2, 965-2, 976
  • Journal of Applied Polymer Science, May 2017, pages 1-6
  • Biomedical Reports, September 2014, pages 755-759
  • Journal of Pharmaceutical Sciences, June 2011, pages 2, 020-2, 053
11 Betaine Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Texture agent

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt

Hydration
5 scientific references
  • International Journal of Toxicology, 2018, pages 28S-46S
  • Food Science and Biotechnology, October 2017, pages 1391-1397
  • The Journal of Chemical Physics, June 2015, ePublication
  • The American Journal of Clinical Nutrition, September 2004, pages 539-549
  • Skin Research and Technology, February 2003, pages 50-58
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Dihydroxypentane

Hydration
4 scientific references
  • https://thedermreviewcom/pentylene-glycol/
  • Regulatory Toxicology and Pharmacology, July 2017, pages 106-111
  • Prospector, June 2015, ePublication
  • International Journal of Toxicology, October 2012, pages 147S-168S
13 Butylene Glycol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Texture agent, Solvent

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate monomers

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Poly(oxy-1,2-ethanediyl), .alpha.-carboxymethyl-.omega.-hydroxy-, C12-14-isoalkyl ethers, sodium salts (7 mol EO average molar ratio)

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Siloxanes and silicones, di-Me, crosspolymers with C3-20 alkyl groups

Silicone
17 Polyisobutene Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Homopolymer of 2-methyl-1 propene

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of ammonium acryloyldimethyltaurate and vinylpyrrolidone monomers

Hydration
19 Vinyl Dimethicone Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Silicones and siloxanes, dimethyl, ethenyl methyl, ethenyldimethylsilyl terminated

Silicone
20 Tromethamine pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt

Soothing Dark Spot Fading
8 scientific references
  • How to Care for Red, Sensitive Skin
  • 7 Best Products for Sensitive Skin
  • Skincare Tips for Calming Redness
  • Skin-Soothing Ingredients
  • How the Paula’s Choice CALM Collection Works
  • The Best Moisturizers for Sensitive Skin
  • The Best Ways to Treat Acne and Sensitive Skin
  • Skin Care for Extremely Dry, Sensitive Skin
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Exfoliant, Preservative

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Salicylic acid

Anti-Acne Anti-Aging Blackhead Reducing
10 scientific references
  • Experimental Dermatology, July 2019, pages 786-794
  • European Commission Scientific Committee on Consumer Safety, June 2019, pages 1-70
  • Regulatory Toxicology and Pharmacology, April 2018, pages 245-251
  • Journal of Cosmetic Science, January-February 2017, pages 55-58
  • Clinical, Cosmetic, and Investigational Dermatology, August 2015, pages 455-461
  • Clinical, Cosmetic, and Investigational Dermatology, November 2010, pages 135-142
  • Seminars in Cutaneous Medicine and Surgery, September 2008, pages 170-176
  • Journal of the American Academy of Dermatology, April 2007, pages 651-663
  • International Journal of Cosmetic Science, February 2000, pages 21-52
  • Seminars in Dermatology, December 1990, pages 305-308
23 Zinc PCA Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Proline, 5-oxo-, zinc salt

Hydration
24 Carbomer Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, hydrogenated

Hydration
4 scientific references
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Nanocosmetics, June 2019, pages 95–140
  • Current Drug Delivery, 2016, pages 111–120
  • Pharmaceutical Research, February 2013, pages 538–55
26 Isododecane Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Solvent

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,2,4,6,6-Pentamethylheptane; Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction, hydrogenated

27 Allantoin Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Soothing

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urea, (2,5-dioxo-4-imidazolidinyl)-

Soothing
8 scientific references
  • Chemistry Series, March 2020, pages 7-21
  • Molecules, June 2019, pages 1-33
  • European Journal of Pharmacology, February 2018, pages 68-78
  • Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
  • Pharmacognosy Review, Volume 5, July-December 2011
  • International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
  • Journal of Occupational Medicine and Toxicology, October 2008, ePublication
  • https://wwwaccessdatafdagov/scripts/cdrh/cfdocs/cfcfr/CFRSearchcfm?CFRPart=347&showFR=1
28 Dimethyl Sulfone Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Solvent

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dimethyl sulphone

29 Panthenol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
30 Polyquaternium-51 Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-(N,N,N-Trimethylamino)ethyl 2-(2-methyl-2-propenoyloxy)ethyl phosphate inner salt, polymer with butyl 2-methyl-2-propenoate

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

D-Glucopyranose, oligomers, decyl octyl glycosides

32 Sorbitan Oleate Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sorbitan oleate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

4-Methyl-1-(1-methylethyl)-3-cyclohexen-1-ol

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Melaleuca Alternifolia Leaf Oil is the oil distilled from the leaves of the Tea Tree, Melaleuca alternifolia, Myrtaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
36 Xanthan Gum Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant, Texture agent

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Xanthan gum

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Melia Azadirachta Leaf Extract is an extract of the leaves of the Neem Tree, Melia azadirachta L., Meliaceae

Anti-Aging
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Melia Azadirachta Flower Extract is an extract of the flowers of the Neem Tree, Melia Azadirachta L., Meliaceae

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration
5 scientific references
  • International Journal of Toxicology, September 2020, pages 34-35
  • Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
  • International Journal of Toxicology, January 2003, pages 4-5
  • Food and Chemical Toxicology, January 2000, pages 79-98
  • Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Coccinia Indica Fruit Extract is an extract of the fruit of Coccinia indica, Cucurbitaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ocimum Sanctum Leaf Extract is an extract of the leaves of Ocimum sanctum, Labiatae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Plant extract

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Aloe Barbadensis Flower Extract is an extract of the flowers of the aloe, Aloe barbadensis, Liliaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Solanum Melogena Fruit Extract is an extract of the fruit of the Eggplant, Solanum melongena L., Solanaceae

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Curcuma Longa Root Extract is an extract of the rhizomes of the Turmeric, Curcuma longa L., Zingiberaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Corallina Officinalis Extract is an extract of the Alga, Corallina officinalis L., Corallinaceae

Hydration Anti-Aging
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
47 Ceramide NP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Hydration Anti-Aging
11 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium hydrogen N-(1-oxooctadecyl)-L-glutamate

Hydration
49 Tocopherol Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

49th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E

Anti-Aging Evens Skin Tone Soothing
4 scientific references
  • Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
  • Journal of Investigative Dermatology, November 2001, pages 1212-1217
  • Canadian Family Physician, July 2006, pages 855-856
  • Dermatologic Surgery, April 1999, pages 311-315
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

50th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lactococcus Ferment Lysate is a lysate of the fermentation product of Lactococcus

Anti-Aging
51 Decyl Glucoside Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant, Texture agent

51st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

D-Glucoside, Decyl

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
UV filter, Humectant, Emollient, Occlusive, Antioxidant, Plant extract, Preservative

52nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Camellia Sinensis Leaf Extract is an extract of the leaves of the Tea, Camellia sinensis, Theaceae

Anti-Aging Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

53rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Centella Asiatica Leaf Extract is an extract of the leaves of the Hydrocotyl, Centella asiatica L., Apiaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

54th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cladosiphon Okamuranus Extract is an extract of the Alga, Cladosiphon okamuranus, Chordariaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing, Plant extract

55th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Salix Alba Bark Extract is an extract of the bark of the White Willow, Salix alba L., salicaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

56th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Coffea Arabica Seed Extract is an extract of the beans of the Coffee plant, Coffea arabica L., Rubiaceae

Anti-Aging
1 scientific reference
  • Related Articles
57 Sodium Chloride Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

57th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium chloride

58 Phenylpropanol Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

58th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3-Phenylpropan-1-ol; Phenethyl carbinol

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

59th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Citrus Aurantium Bergamia Leaf Extract is an extract of the leaves, Citrus aurantium bergamia, Rutaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

60th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

4-Oxovaleric acid

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

61st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium 4-oxovalerate

Hydration
3 scientific references
  • Natural Microbiology, December 2017, pages 1, 624-1, 634
  • Journal of Food Science, June 2008, pages M230-M244
  • Lebenson Wiss Technology, December 2004, pages 865–871
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant, Plant extract, Preservative

62nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Pinus Densiflora Leaf Extract is the extract of the leaves of the Pine, Pinus densiflora, Pinaceae

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Frequently asked questions

What ingredients are in Red Serum 2.0?

WATER, DIPROPYLENE GLYCOL, GLYCERIN, XYLITOL, ALCOHOL DENAT., PROPANEDIOL, 1,2-HEXANEDIOL, NIACINAMIDE, DIETHOXYETHYL SUCCINATE, TREHALOSE, BETAINE, PENTYLENE GLYCOL, BUTYLENE GLYCOL, SODIUM ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, SODIUM C12-14 SEC-PARETH-8 CARBOXYLATE, DIMETHICONE CROSSPOLYMER, POLYISOBUTENE, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, VINYL DIMETHICONE, TROMETHAMINE, DIPOTASSIUM GLYCYRRHIZATE, SALICYLIC ACID, ZINC PCA, CARBOMER, HYDROGENATED LECITHIN, ISODODECANE, ALLANTOIN, DIMETHYL SULFONE, PANTHENOL, POLYQUATERNIUM-51, CAPRYLYL/CAPRYL GLUCOSIDE, SORBITAN OLEATE, 4-TERPINEOL, MELALEUCA ALTERNIFOLIA LEAF OIL, ADENOSINE, XANTHAN GUM, ETHYLHEXYLGLYCERIN, MELIA AZADIRACHTA LEAF EXTRACT, MELIA AZADIRACHTA FLOWER EXTRACT, CAPRYLIC/CAPRIC TRIGLYCERIDE, COCCINIA INDICA FRUIT EXTRACT, OCIMUM SANCTUM LEAF EXTRACT, ALOE BARBADENSIS FLOWER EXTRACT, SOLANUM MELONGENA FRUIT EXTRACT, CURCUMA LONGA ROOT EXTRACT, CORALLINA OFFICINALIS EXTRACT, CERAMIDE NP, SODIUM STEAROYL GLUTAMATE, TOCOPHEROL, LACTOCOCCUS FERMENT LYSATE, DECYL GLUCOSIDE, CAMELLIA SINENSIS LEAF EXTRACT, CENTELLA ASIATICA LEAF EXTRACT, CLADOSIPHON OKAMURANUS EXTRACT, SALIX ALBA BARK EXTRACT, COFFEA ARABICA SEED EXTRACT, SODIUM CHLORIDE, PHENYLPROPANOL, CITRUS AURANTIUM BERGAMIA LEAF EXTRACT, LEVULINIC ACID, SODIUM LEVULINATE, PINUS DENSIFLORA LEAF EXTRACT.

What are the active ingredients in Red Serum 2.0?

NIACINAMIDE, SALICYLIC ACID, PANTHENOL, CERAMIDE NP.

How do I use Red Serum 2.0?

After cleansing and toning, apply 2–3 pumps to the entire face. Gently pat into skin until absorbed. Follow with moisturizer. Use daily, morning and evening.

What skin types is Red Serum 2.0 good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is Red Serum 2.0 good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is Red Serum 2.0 fungal acne safe?

2 ingredients could feed malassezia: Sorbitan Oleate, Melaleuca Alternifolia Leaf Oil. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use Red Serum 2.0 while pregnant?

It contains Salicylic Acid, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.

Is Red Serum 2.0 fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does Red Serum 2.0 contain alcohol?

Yes — it contains Alcohol Denat..

Is Red Serum 2.0 silicone free?

No — it contains Dimethicone Crosspolymer, Vinyl Dimethicone.

Does Red Serum 2.0 contain essential oils?

Yes — it contains Melaleuca Alternifolia Leaf Oil.

Is Red Serum 2.0 paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with Red Serum 2.0?

It layers well with Azelaic acid, Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides. Take more care combining it with Retinoids (retinol, retinal), Vitamin C (L-ascorbic acid), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide — use them in separate routines or on alternate days.

When should I apply Red Serum 2.0?

Use it morning and evening, after toner, before moisturiser.

How many ingredients does Red Serum 2.0 have?

It lists 62 ingredients, of which 4 are recorded as actives.

Who makes Red Serum 2.0?

Medicube, a brand based in Korea.

Brand
Medicube
Country
Korea

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