-
Estimated level
- 30–80%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Hydration
3 scientific references
- Skin Research and Technology, May 2015, pages 131-136
- Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
- Journal of Cosmetic Science, September-October 1993, pages 249-262
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Occlusive, Texture agent
2nd on the list, which puts it at an estimated 5–20% of the formula.
Ethenol, homopolymer
Synthetic polymer
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Emollient, Solvent
3rd on the list, which puts it at an estimated 5–20% of the formula.
2-Octyldodecan-1-ol
Hydration
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
4th on the list, which puts it at an estimated 2–10% of the formula.
2-Methyl-1,3-propanediol
Hydration
3 scientific references
- PubChem, Accessed April 2021, ePublication
- Cosmetic Ingredient Review, June 2018, pages 1-73
- Contact Dermatitis, September 2017, pages 159-162
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Texture agent, Solvent
5th on the list, which puts it at an estimated 2–10% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7)
(R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Hydration
5 scientific references
- CosmeticsInfoorg, Accessed March 2021, ePublication
- US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
- International Journal of Toxicology, May 2011, pages 5S-16S
- Skin Research and Technology, November 2007, pages 417-24
- Journal of the American College of Toxicology, September 1985, pages 223-248
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Active
6th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
Soothing
Anti-Aging
Pore Minimizer
15 scientific references
- International Journal of Dermatology, February 2021, pages 166-173
- Biomolecules & Therapeutics, July 2019, pages 562-569
- Experimental Dermatology, February 2019, pages 15-22
- Dermatologic Therapy, September 2017, ePublication
- Journal of Investigative Dermatology, May 2017, page S116
- International Journal of Pharmaceutics, March 2017, pages 158-162
- Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
- Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
- Skin Pharmacology and Physiology, June 2014, pages 311-315
- International Journal of Pharmacy, January 2013, pages 192-201
- Dermatoendrocrinology, July 2012, pages 308-319
- International Journal of Toxicology, September 2005, pages 1-31
- Dermatologic Surgery, July 2005, pages 860-865
- International Journal of Cosmetic Science, October 2004, pages 231-238
- Journal of Cosmetic Dermatology, April 2004, pages 88-93
-
Estimated level
- 1–5%
-
Confidence
- Moderate — INCI order above the 1% line
7th on the list, which puts it at an estimated 1–5% of the formula.
Decanoic acid, ester with 1,2,3-propanetriol octanoate;
Glycerides, mixed decanoyl and octanoyl
Hydration
5 scientific references
- International Journal of Toxicology, September 2020, pages 34-35
- Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
- International Journal of Toxicology, January 2003, pages 4-5
- Food and Chemical Toxicology, January 2000, pages 79-98
- Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Solvent
8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Alginic acid, sodium salt
Anti-Aging
Hydration
Soothing
8 scientific references
- 5 Super Anti-Aging Antioxidants Your Skin Needs
- How to Keep Your Neck & Chest Looking Young
- Acne & Aging Skin
- How to Diminish Uneven Skin Tone and Get Your Glow Back
- What Are Peptides and What Do They Do for Skin?
- The Truth About Firming Creams
- Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
- Anti-Aging Superstars
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sorbitan, mono-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs., (Z)-
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient, Texture agent
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2,2-bis[[(2-Ethyl-1-oxohexyl)oxy]methyl]propane-1,3-diyl bis(2-ethylhexanoate)
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Texture agent
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Pullulan is a polysaccharide produced from starch by cultivating the yeast, Aureobasidium pullulans
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Simmondsia Chinensis Seed Oil is the fixed oil expressed or extracted from seeds of the desert shrub, Jojoba, Simmondsia chinensis, Buxaceae
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
ester of decaglycerol and oleic acid
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient, Surfactant
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Stearic acid, monoester with glycerol
Hydration
3 scientific references
- Cosmeticsinfoorg, Accessed November 2021, ePublication
- Drugs in Context, April 2018, pages 1-14
- International Journal of Toxicology, May 2007, pages 1–30
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- (100 mol EO average molar ratio)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
UV filter, Texture agent
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Titanium dioxide (CI 77891)
Anti-Aging
10 scientific references
- Journal of Cosmetic Dermatology, February 2021, pages 532-537
- Frontiers in Bioengineering and Biotechnology, June 2020
- Journal of Nanoparticle Research, March 2020
- Journal of the European Academy of Dermatology and Venereology, November 2019, pages 34-46
- Photodermatology, Photoimmunology and Photomedicine, November 2019, pages 442-446
- Journal of Cosmetic Science, September 2019, pages 223-234
- Materials, July 2019, pages 1-24
- Photodermatology, Photoimmunology, and Photomedicine, April 2011, pages 58-67
- Skin Therapy Letter, July-August 2008, pages 5-7
- Environmental and Health Perspectives, July 2008, pages 893
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, chloride, reaction products with hectorite
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Fluorphlogopite, Mg3K[AlF2O(SiO3)3] (synthetic)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent, Fragrance / colour
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Mica is a series of silicate minerals of varying chemical composition but with similar physical properties. Mica may have well-defined cleavage and split into very thin sheets.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Exfoliant, Texture agent
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Microcrystalline Cellulose is the isolated, colloidal crystalline portion of cellulose fibers.
Anti-Aging
3 scientific references
- 3 Biotech, June 2021, pages 1-13
- IOP Conference Series: Materials Science and Engineering, March 2017, pages 1-5
- Cosmetic Ingredient Review, March 2009, pages 1-49
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
Hydration
5 scientific references
- PLoS One, October 2016, ePublication
- Contact Dermatitis, May 2016, pages 281-288
- International Journal of Toxicology, September 2013, pages 5S-21S
- Personal Care, 2008, pages 1-4
- Cosmetic Science Technology, 2006, pages 1-11
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Plant extract
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sphingomonas Ferment Extract is an extract of the product obtained by the fermentation of Sphingomonas
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Soothing
8 scientific references
- PubChem, Accessed May 2021, ePublication
- Cosmetic Ingredient Review, September 2020, pages 1-38
- Experimental Dermatology, August 2014, pages 553-554
- Journal of Investigative Dermatology, August 2011, pages 526-546
- International Journal of Cosmetic Science, December 2006, pages 447-451
- British Journal of Pharmacology, October 2008, issue 4, pages 475-486
- PloS One, May 2008 (ePublication)
- >International Journal of Cosmetic Science, August 2006, pages 447-451
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Texture agent
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cellulose, carboxymethyl ether, sodium salt
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Chelator
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Myo-Inositol, hexakis(dihydrogen phosphate), sodium salt
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Deoxyribonucleic acid, sodium salts
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Exfoliant, Texture agent
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tin dioxide (CI 77861)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycine, N-(N-L-.gamma.-glutamyl-L-cysteinyl)-
Anti-Aging
8 scientific references
- Journal of Cosmetic Dermatology, June 2019, pages 728–737
- Clinical Cosmetic and Investigative Dermatology, April 2017, pages 147-153 and October 2014, pages 267-274
- Nutrients, August 2017, pages 1-27
- DermatoEndocrinology, July 2012, pages 308-319
- Journal of Agricultural and Food Chemistry, 2011, pages 3, 940-3, 949
- The Dermatologist, October 2011, volume 19, issue 10
- Journal of Dermatologic Science, May 2010, pages 85-90
- Free Radical Biology and Medicine, October 1994, pages 333-349
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
N-acetyl-.alpha.-D-glucosamine
Hydration
Soothing
Evens Skin Tone
6 scientific references
- Cosmetic Ingredient Review, July 2022, pages 1-25
- International Journal of Pharmaceutics, March 2020, pages 1-10
- Life Sciences, May 2016, pages 21-29
- Drug Design, Development and Therapy, August 2014, pages 1, 923-1, 928
- Journal of Cosmetic Dermatology, June 2013, pages 96-102; and December 2006, pages 309-315
- Dermato-endocrinology, July 2012, pages 253-258
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Soothing
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Urea, (2,5-dioxo-4-imidazolidinyl)-
Soothing
8 scientific references
- Chemistry Series, March 2020, pages 7-21
- Molecules, June 2019, pages 1-33
- European Journal of Pharmacology, February 2018, pages 68-78
- Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
- Pharmacognosy Review, Volume 5, July-December 2011
- International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
- Journal of Occupational Medicine and Toxicology, October 2008, ePublication
- https://wwwaccessdatafdagov/scripts/cdrh/cfdocs/cfcfr/CFRSearchcfm?CFRPart=347&showFR=1
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
Hydration
Soothing
7 scientific references
- The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
- International Journal of Cosmetic Science, December 2019, pages 534-547
- Journal of Cosmetic Dermatology, January 2019, pages 346-354
- Cosmetic Ingredient Review, March 2018, pages 1-51
- The Journal of Dermatological Treatment, August 2017, pages 173-180
- Journal of Cosmetic Science, August 2011, pages 361-370
- American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Emollient, Occlusive
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagens, hydrolyzates. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of hoofs and horns composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin.
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Chelator
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
D-Glucono-1,5-lactone
Evens Skin Tone
Anti-Aging
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Texture agent
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
D-Mannitol
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Plant extract
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Centella Asiatica Leaf Extract is an extract of the leaves of the Hydrocotyl, Centella asiatica L., Apiaceae
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Occlusive, Texture agent, Solvent
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
Hydration
Anti-Aging
6 scientific references
- Journal of Pharmaceutical Investigation, March 2021, pages 223-231
- International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
- International Journal of Cosmetic Science, August 2016, ePublication
- British Journal of Dermatology, July 2008, pages 23-34
- Journal of Cosmetic Dermatology, June 2007, pages 75-82
- Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lactobacillus Extracellular Vesicles are the extracellular vesicles released into and isolated from the growth media removed from cell cultures of the microorganism Lactobacillus.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Exfoliant, Texture agent
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Silicic acid; synthetic amorphous silicon dioxide
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Chelator, pH adjuster
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Hydroxy-1,2,3-propanetricarboxylic acid
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
Hydration
Anti-Aging
Soothing
5 scientific references
- Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
- Journal of Cosmetic Dermatology, July 2014, pages 277-287
- Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
- DermatoEndocrinology, July-December 2012, pages 253-258
- Journal of Drugs in Dermatology, September 2011, pages 990-1000
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octane-1,2-diol
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active, Peptide
43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues
Anti-Aging
Hydration
6 scientific references
- Cosmetics, November 2020, Issue 7, Volume 4, page 91
- La Clinica Terapeutica, November 2020, pages e539-e548
- https://wwwcir-safetyorg/sites/default/files/AcetylHexapeptide-8pdf
- Cutaneous and Ocular Toxicology, March 2015, pages 46-52
- European Journal of Pharmaceutical Sciences, February 2015, pages 27-35
- Dermatologic Therapy, September-October 2007, issue 5, pages 343-349