VT Cosmetics PDRN R5 Firming Ampoule

VT Cosmetics

PDRN R5 Firming Ampoule

face ampoule

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Fit by skin type

General, ingredient-based — not your personalized match.

Dry
79%
Combination (dry)
79%
Balanced
91%
Combination (oily)
61%
Oily
61%

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38
Ingredients
4
Benefits
4
Actives
Find Dupes

The VT Cosmetics PDRN R5 Firming Ampoule helps firm, hydrate, and strengthen the skin barrier for smoother, healthier-looking skin. Formulated with VT’s Phyto PDRN™, five skin-replenishing ceramides, Centella asiatica, peptides, panthenol, squalane, and polyglucuronic acid, this nourishing ampoule delivers lasting hydration while helping improve skin elasticity and resilience. Antioxidant-rich botanical extracts and collagen amino acids leave skin feeling softer, calmer, and visibly refreshed with a lightweight, comfortable finish.

Key Insights

Benefits

4
Anti-Aging
Evens Skin Tone
Hydration
Soothing

Active Ingredients

4
Carrier peptides Ceramides Neuropeptides Vitamin B5 (panthenol)

Risks

1
Synthetic polymer

Full Ingredients

38 total
WATER ISOPROPYL MYRISTATE CAPRYLIC/CAPRIC TRIGLYCERIDE CETYL ETHYLHEXANOATE PROPANEDIOL GLYCERIN POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE POLYGLYCERYL-3 DIISOSTEARATE PEG-30 DIPOLYHYDROXYSTEARATE 1,2-HEXANEDIOL HYDROXYACETOPHENONE ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER ARGININE HELIANTHUS ANNUUS SEED OIL TOCOPHEROL ADENOSINE CERAMIDE NP Ceramides ADANSONIA DIGITATA SEED OIL DISODIUM EDTA HYDROGENATED LECITHIN ALLANTOIN SQUALANE LACTOBACILLUS/SOYMILK FERMENT FILTRATE PANTHENOL Vitamin B5 (panthenol) POLYGLUCURONIC ACID COLLAGEN AMINO ACIDS CERAMIDE AS Ceramides CERAMIDE NS Ceramides BUTYLENE GLYCOL PENTYLENE GLYCOL CERAMIDE AP Ceramides CERAMIDE EOP Ceramides HAEMATOCOCCUS PLUVIALIS EXTRACT CENTELLA ASIATICA EXTRACT PANAX GINSENG ROOT EXTRACT COPPER TRIPEPTIDE-1 Carrier peptides ACETYL HEXAPEPTIDE-8 Neuropeptides SODIUM DNA

About PDRN R5 Firming Ampoule

Overview

PDRN R5 Firming Ampoule is a cushioning ampoule from VT Cosmetics, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 38 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as moderately cushioned — emollient enough to feel like a cream, without the heaviest occlusives near the top. The oils in it point to a dewy, emollient finish rather than a matte one. Hydration is handled by Propanediol, Glycerin and Panthenol, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: Very high. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Propanediol, Glycerin, Panthenol and Collagen Amino Acids.

Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Cetyl Ethylhexanoate, Allantoin, Panthenol and Centella Asiatica Extract.

Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Ceramide NP, Hydrogenated Lecithin, Squalane and Panthenol.

Who it suits

On richness alone it suits Balanced skin best, and is the least natural fit for Combination (oily) and Oily skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on antioxidant protection, oil control, brightening and tone and cell renewal. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, silicone-free and microplastic-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • Silicone-free
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • 7 ingredients could feed malassezia (fungal acne)

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin

May suit

  • Dry skin
  • Combination (dry) skin

Less suitable for

  • Combination (oily) skin
  • Oily skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 24 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 16 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 7 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Evens Skin Tone 1 ingredient

    Brightens and balances complexion for a more uniform appearance

Does not target

Anti-Acne Blackhead Reducing Dark Spot Fading Oil Control Pore Minimizer Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

Water

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
Isopropyl Myristate

2nd on the list, which puts it at an estimated 5–20% of the formula.

Tetradecanoic acid, isopropyl ester

Hydration
Caprylic/capric Triglyceride

3rd on the list, which puts it at an estimated 5–20% of the formula.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration
Cetyl Ethylhexanoate

4th on the list, which puts it at an estimated 2–10% of the formula.

Hexadecyl 2-ethylhexanoate

Hydration
Propanediol

5th on the list, which puts it at an estimated 2–10% of the formula.

1,3-dihydroxypropane

Hydration
Glycerin

6th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
Polyglyceryl-3 Diisostearate

8th on the list, which puts it at an estimated 1–5% of the formula.

1,2,3-Propanetriol, homopolymer, isodecanoates (1:2) (3 mol glycerol average molar ratio)

Hydration
Hydroxyacetophenone

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone

Anti-Aging Hydration
Arginine

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

L-Arginine

Hydration Anti-Aging
Helianthus Annuus Seed Oil

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Helianthus Annuus Seed Oil is the oil expressed from the seeds of the Sunflower, Helianthus annuus L., Compositae

Anti-Aging Hydration
Tocopherol

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E

Anti-Aging Evens Skin Tone Soothing
Adenosine

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration Very high

Ingredients that pull and hold water in the upper layers of skin

Barrier support Moderate

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control None

Ingredients that moderate sebum or absorb shine

Brightening None

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Moderate

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling Low

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (8)

Supporting ingredients (30)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Isopropyl Myristate Caprylic/capric Triglyceride Cetyl Ethylhexanoate Propanediol Glycerin Polyglyceryl-2 Dipolyhydroxystearate Polyglyceryl-3 Diisostearate Peg-30 Dipolyhydroxystearate 1,2-hexanediol Hydroxyacetophenone Acrylates/c10-30 Alkyl Acrylate Crosspolymer Arginine Helianthus Annuus Seed Oil Tocopherol Adenosine Adansonia Digitata Seed Oil Disodium Edta Hydrogenated Lecithin Allantoin Squalane Lactobacillus/soymilk Ferment Filtrate Polyglucuronic Acid Collagen Amino Acids Butylene Glycol Pentylene Glycol Haematococcus Pluvialis Extract Centella Asiatica Extract Panax Ginseng Root Extract Sodium DNA

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Silicone-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • No animal-derived ingredients

Contains

  • Facial oils

    Helianthus Annuus Seed Oil, Adansonia Digitata Seed Oil

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Vitamin C (L-ascorbic acid)
  • Retinoids (retinol, retinal)
  • AHAs (glycolic, lactic)
  • BHA (salicylic acid)
  • PHAs (gluconolactone)
  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • Benzoyl peroxide

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Treat" step.

  • Apply to clean, dry skin and give it a minute to absorb before the next layer.
  • Introduce one new treatment at a time so you can identify what is working.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Nothing in this formula is on the standard pregnancy-caution list. That is not clearance — ask your doctor about anything you use daily.
Fungal acne (malassezia)
7 ingredients could feed malassezia: Isopropyl Myristate, Polyglyceryl-2 Dipolyhydroxystearate, Polyglyceryl-3 Diisostearate, Peg-30 Dipolyhydroxystearate, Helianthus Annuus Seed Oil, Adansonia Digitata Seed Oil, Lactobacillus/soymilk Ferment Filtrate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 38 ingredients on the label.

8
Active

Changes how skin behaves rather than how it feels

6
Emollient

Softens and smooths by filling gaps between skin cells

6
Solvent

Dissolves and carries everything else

6
Texture agent

Sets the thickness, spread and stability of the formula

4
Humectant

Draws water into the upper layers of skin

4
Occlusive

Forms a film that slows water loss

4
Plant extract

Botanical material, usually for antioxidants or scent

4
Surfactant

Lifts oil and dirt, or holds oil and water together

3
Antioxidant

Neutralises free radicals from UV and pollution

2
Soothing

Calms visible redness and irritation

2
Peptide

Amino-acid chains that signal for repair or firmness

1
Chelator

Binds trace metals that would otherwise spoil the formula

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Isopropyl Myristate Emollient
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Texture agent

2nd on the list, which puts it at an estimated 5–20% of the formula.

Tetradecanoic acid, isopropyl ester

Hydration
3 Caprylic/capric Triglyceride
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line

3rd on the list, which puts it at an estimated 5–20% of the formula.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration
5 scientific references
  • International Journal of Toxicology, September 2020, pages 34-35
  • Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
  • International Journal of Toxicology, January 2003, pages 4-5
  • Food and Chemical Toxicology, January 2000, pages 79-98
  • Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
4 Cetyl Ethylhexanoate Emollient
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

4th on the list, which puts it at an estimated 2–10% of the formula.

Hexadecyl 2-ethylhexanoate

Hydration
2 scientific references
  • Engineering in Life Sciences, March 2019, pages 370-388
  • International Journal of Toxicology, Nov-Dec 2015, pages 61S-73S
5 Propanediol Texture agent
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

5th on the list, which puts it at an estimated 2–10% of the formula.

1,3-dihydroxypropane

Hydration
4 scientific references
  • PubChem Compound Summary, April 2021, ePublication
  • SpecialChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Cosmetics & Toiletries, May 2013, pages 81-86
6 Glycerin Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

6th on the list, which puts it at an estimated 2–10% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
7 Polyglyceryl-2 Dipolyhydroxystearate
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line

7th on the list, which puts it at an estimated 1–5% of the formula.

Octadecanoic acid, 12-hydroxy-, homopolymer, ester with oxybis(propanediol)

8 Polyglyceryl-3 Diisostearate Surfactant
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

8th on the list, which puts it at an estimated 1–5% of the formula.

1,2,3-Propanetriol, homopolymer, isodecanoates (1:2) (3 mol glycerol average molar ratio)

Hydration
3 scientific references
  • Colloids and Surfaces, June 2017, pages 279–286
  • International Journal of Toxicology, August 2023, pages 5S–101S
  • Scientific Reports, March 2023, pages 1–14
9 Peg-30 Dipolyhydroxystearate Surfactant
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Surfactant

9th on the list, which puts it at an estimated 1–5% of the formula.

12-Hydroxyoctadecanoic acid, homopolymer, diesters with .alpha.-hydro-.omega.-hydroxypoly(oxy-1,2-ethanediyl) (30 mol EO average molar ratio)

10 1,2-hexanediol Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

11 Hydroxyacetophenone Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone

Anti-Aging Hydration
4 scientific references
  • Journal of Oleo Science, February 2019, pages 183-191
  • Applied Environmental Microbiology, June 2018, ePublication
  • Journal of Biosciences, May-June 2004, pages 345-353
  • Scientific Reports, April 2021, pages 1–7
12 Acrylates/c10-30 Alkyl Acrylate Crosspolymer Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol

Synthetic polymer
13 Arginine
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

L-Arginine

Hydration Anti-Aging
6 scientific references
  • Biobased Surfactants (Second Edition), 2019, pages 413-445
  • Scientific Reports, February 2016, pages 1-10
  • Cosmetic Ingredient Review, October 2012, pages 1-35
  • Journal of Advanced Research, July 2010, pages 169–177
  • International Journal of Cosmetic Science, April 2005, page 139
  • Wound Repair and Regeneration, November-December 2003, pages 419-423
14 Helianthus Annuus Seed Oil Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Helianthus Annuus Seed Oil is the oil expressed from the seeds of the Sunflower, Helianthus annuus L., Compositae

Anti-Aging Hydration
4 scientific references
  • Pediatric Dermatology, August 2018, ePublication; and January-February 2013, pages 42-50
  • Chemicke Zvesti, May 2018, pages 2, 607-2, 615
  • International Journal of Molecular Sciences, December 2017, ePublication
  • Dermatology, October 2014, pages 230-239
15 Tocopherol Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E

Anti-Aging Evens Skin Tone Soothing
4 scientific references
  • Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
  • Journal of Investigative Dermatology, November 2001, pages 1212-1217
  • Canadian Family Physician, July 2006, pages 855-856
  • Dermatologic Surgery, April 1999, pages 311-315
16 Adenosine
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
17 Ceramide NP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Hydration Anti-Aging
11 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
18 Adansonia Digitata Seed Oil Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Adansonia Digitata Seed Oil is the oil expressd from the seeds of the Monkey Bread Tree or the Baobab, Adansonia digitata L., Bombacaceae

Anti-Aging Hydration Soothing
19 Disodium Edta Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Chelator

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Disodium dihydrogen ethylenediaminetetraacetate

20 Hydrogenated Lecithin Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, hydrogenated

Hydration
4 scientific references
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Nanocosmetics, June 2019, pages 95–140
  • Current Drug Delivery, 2016, pages 111–120
  • Pharmaceutical Research, February 2013, pages 538–55
21 Allantoin Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Soothing

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urea, (2,5-dioxo-4-imidazolidinyl)-

Soothing
8 scientific references
  • Chemistry Series, March 2020, pages 7-21
  • Molecules, June 2019, pages 1-33
  • European Journal of Pharmacology, February 2018, pages 68-78
  • Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
  • Pharmacognosy Review, Volume 5, July-December 2011
  • International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
  • Journal of Occupational Medicine and Toxicology, October 2008, ePublication
  • https://wwwaccessdatafdagov/scripts/cdrh/cfdocs/cfcfr/CFRSearchcfm?CFRPart=347&showFR=1
22 Squalane Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,6,10,15,19,23-Hexamethyltetracosane

Hydration Anti-Aging
9 scientific references
  • Cosmetics Ingredient Review, 2019, ePublication
  • ACS Open, July 2017, pages 3, 989–3, 996
  • Indian Journal of Dermatology, May-June 2016, pages 279-297
  • The Journal of Clinical and Aesthetic Dermatology, June 2014, pages 25-32
  • Journal of Cosmetic Science, January-February 2013, pages 59-66
  • Advances in Food and Nutrition Research, 2012, pages 223-233
  • Molecules, January 2009, pages 540-554
  • Journal of Investigative Dermatology, November 2006, pages 2, 430-2, 437
  • Free Radical Research, April 2002, pages 471-477
23 Lactobacillus/soymilk Ferment Filtrate Plant extract
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lactobacillus/Soymilk Ferment Filtrate is a filtrate of the product obtained by the fermentation of Soymilk by the microorganism Lactobacillus

24 Panthenol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
25 Polyglucuronic Acid
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

D-Glucuronic Acid Homopolymer

Hydration
2 scientific references
  • International Journal of Cosmetic Science, February 2011, pages 1–16
  • Glycobiology, December 2010, pages 1, 547–1, 573
26 Collagen Amino Acids Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Amino Acids derived from collagen

Hydration
27 Ceramide AS Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide AS

Anti-Aging Hydration
2 scientific references
  • UL Prospector, Accessed February 2023, Webpage 9 American Journal of Clinical Dermatology, July 2021, pages 853-866
  • International Journal of Toxicology, Nov-Dec 2020, pages 52-25S
28 Ceramide NS Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NG,Ceramide NS,1,3-Hexadecanediol, 2-Hexadecanamide,Palmitoyl-C16-Dihydrosphingosine,1-Stearoyl-C18-Sphingosine

Hydration Anti-Aging
9 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • PLoS ONE, October 2018, pages 1-18
  • Scientific Reports, November 2015, pages 1-11
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, Volume 4, 2003, pages 107-129
  • Journal of Investigative Dermatology, November 2001, pages 1126-1136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
29 Butylene Glycol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Texture agent, Solvent

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
30 Pentylene Glycol Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Dihydroxypentane

Hydration
4 scientific references
  • https://thedermreviewcom/pentylene-glycol/
  • Regulatory Toxicology and Pharmacology, July 2017, pages 106-111
  • Prospector, June 2015, ePublication
  • International Journal of Toxicology, October 2012, pages 147S-168S
31 Ceramide AP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3,4-Octadecanetriol, 2-(2-Hydroxy) Stearamide

Hydration Anti-Aging
10 scientific references
  • International Journal of Toxicology,  2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Pharmaceutical Research, November 2012, pages 538-551
  • Journal of Lipid Research,  July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research,  September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Journal of Investigative Dermatology,  November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
32 Ceramide EOP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide EOP,1,3,4-Octadecanetriol, 2-Stearoyloxyheptacosamide,Stearoyloxyheptacosanoyl-C18-Phytosphingosine,Stearoyloxyheptacosanoyl-4-Hydroxysphinganine

Hydration Anti-Aging
9 scientific references
  • International Journal of Toxicology,  2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research,  July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research,  September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology,  2003, pages 107-129
  • Journal of Investigative Dermatology,  November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
33 Haematococcus Pluvialis Extract Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant, Plant extract

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Haematococcus Pluvialis Extract is an extract of the Alga, Haematococcus pluvialis, Stephanosphaeraceae

Anti-Aging Soothing
10 scientific references
  • IOP Conference Series: Earth and Environmental Science, May 2021, pages 1-7
  • https://wwwdeepdyvecom/lp/iop-publishing/evaluation-of-sunscreen-cream-incorporated-with-astaxanthin-from-oW84RMbh0Q?articleList=%2Fsearch%3Fquery%3Dhaematococcus%2Bpluvialis%2Bextract
  • Marine Drugs, September 2020, pages 11-22
  • https://wwwdeepdyvecom/lp/pubmed-central/astaxanthin-and-other-nutrients-from-haematococcus-pluvialis-jN1TYzSvFr?articleList=%2Fsearch%3Fquery%3DHaematococcus%2Bpluvialis%2Bextract%2Bsafety
  • Oxidative Medicine and Cellular Longevity, August 2020, pages 1-13
  • https://wwwdeepdyvecom/lp/pubmed-central/purified-astaxanthin-from-haematococcus-pluvialis-promotes-tissue-RFCS2fOQ91?articleList=%2Fsearch%3Fquery%3Dhaematococcus%2Bpluvialis%2Bextract
  • International Journal of Food Science & Technology, January 2019, pages 376-386
  • https://wwwdeepdyvecom/lp/wiley/highly-efficient-preparation-of-free-all-trans-astaxanthin-from-xpc5XSyg0F?articleList=%2Fsearch%3Fquery%3Dhaematococcus%2Bpluvialis%2Bextract
  • International Journal of Molecular Sciences, June 2016, pages 1-13
  • https://wwwdeepdyvecom/lp/pubmed-central/enriched-astaxanthin-extract-from-haematococcus-pluvialis-augments-N3He28IeHZ?articleList=%2Fsearch%3Fquery%3D%2522enriched%2Bastaxanthin%2522
34 Centella Asiatica Extract Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing, Surfactant, Plant extract

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae

Soothing Anti-Aging
6 scientific references
  • Phytomedicine, April 2018, pages 110–119
  • Clinical, Cosmetic, and Investigational Dermatology, August 2017, pages 311–315
  • Indian Journal of Pharmaceutical Sciences, Jan-Feb 2016, pages 27–33
  • Postepy Dermatologii I, February 2013, pages 46–49
  • Indian Journal of Pharmaceutical Sciences, 2010, pages 546–556
  • Scientific Reports, June 2021, ePublication
35 Panax Ginseng Root Extract Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Occlusive, Plant extract

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Panax Ginseng Root Extract is an extract of the roots of the Ginseng, Panax ginseng, Araliaceae

Anti-Aging
36 Copper Tripeptide-1 Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Peptide

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Copper Tripeptide-1 is a copper complex of Tripeptide-1

37 Acetyl Hexapeptide-8 Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active, Peptide

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues

Anti-Aging Hydration
6 scientific references
  • Cosmetics, November 2020, Issue 7, Volume 4, page 91
  • La Clinica Terapeutica, November 2020, pages e539-e548
  • https://wwwcir-safetyorg/sites/default/files/AcetylHexapeptide-8pdf
  • Cutaneous and Ocular Toxicology, March 2015, pages 46-52
  • European Journal of Pharmaceutical Sciences, February 2015, pages 27-35
  • Dermatologic Therapy, September-October 2007, issue 5, pages 343-349
38 Sodium DNA
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Deoxyribonucleic acid, sodium salts

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Frequently asked questions

What ingredients are in PDRN R5 Firming Ampoule?

WATER, ISOPROPYL MYRISTATE, CAPRYLIC/CAPRIC TRIGLYCERIDE, CETYL ETHYLHEXANOATE, PROPANEDIOL, GLYCERIN, POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE, POLYGLYCERYL-3 DIISOSTEARATE, PEG-30 DIPOLYHYDROXYSTEARATE, 1,2-HEXANEDIOL, HYDROXYACETOPHENONE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, ARGININE, HELIANTHUS ANNUUS SEED OIL, TOCOPHEROL, ADENOSINE, CERAMIDE NP, ADANSONIA DIGITATA SEED OIL, DISODIUM EDTA, HYDROGENATED LECITHIN, ALLANTOIN, SQUALANE, LACTOBACILLUS/SOYMILK FERMENT FILTRATE, PANTHENOL, POLYGLUCURONIC ACID, COLLAGEN AMINO ACIDS, CERAMIDE AS, CERAMIDE NS, BUTYLENE GLYCOL, PENTYLENE GLYCOL, CERAMIDE AP, CERAMIDE EOP, HAEMATOCOCCUS PLUVIALIS EXTRACT, CENTELLA ASIATICA EXTRACT, PANAX GINSENG ROOT EXTRACT, COPPER TRIPEPTIDE-1, ACETYL HEXAPEPTIDE-8, SODIUM DNA.

What are the active ingredients in PDRN R5 Firming Ampoule?

CERAMIDE NP, PANTHENOL, CERAMIDE AS, CERAMIDE NS, CERAMIDE AP, CERAMIDE EOP, COPPER TRIPEPTIDE-1, ACETYL HEXAPEPTIDE-8.

How do I use PDRN R5 Firming Ampoule?

After cleansing and toning, apply an appropriate amount evenly to the face. Gently pat until fully absorbed. Follow with moisturizer.

What skin types is PDRN R5 Firming Ampoule good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Combination (oily), Oily skin.

Is PDRN R5 Firming Ampoule good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is PDRN R5 Firming Ampoule fungal acne safe?

7 ingredients could feed malassezia: Isopropyl Myristate, Polyglyceryl-2 Dipolyhydroxystearate, Polyglyceryl-3 Diisostearate, Peg-30 Dipolyhydroxystearate, Helianthus Annuus Seed Oil, Adansonia Digitata Seed Oil, Lactobacillus/soymilk Ferment Filtrate. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use PDRN R5 Firming Ampoule while pregnant?

Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.

Is PDRN R5 Firming Ampoule fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does PDRN R5 Firming Ampoule contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is PDRN R5 Firming Ampoule silicone free?

Yes. Reading the full ingredient list, this formula is silicone-free.

Does PDRN R5 Firming Ampoule contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is PDRN R5 Firming Ampoule paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with PDRN R5 Firming Ampoule?

It layers well with Vitamin C (L-ascorbic acid), Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Azelaic acid. Take more care combining it with Benzoyl peroxide — use them in separate routines or on alternate days.

When should I apply PDRN R5 Firming Ampoule?

Use it morning and evening, after toner, before moisturiser.

How many ingredients does PDRN R5 Firming Ampoule have?

It lists 38 ingredients, of which 8 are recorded as actives.

Who makes PDRN R5 Firming Ampoule?

VT Cosmetics, a brand based in Korea.

Brand
VT Cosmetics
Country
Korea
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