-
Estimated level
- 30–80%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Hydration
3 scientific references
- Skin Research and Technology, May 2015, pages 131-136
- Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
- Journal of Cosmetic Science, September-October 1993, pages 249-262
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Texture agent, Solvent
2nd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7)
(R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Hydration
5 scientific references
- CosmeticsInfoorg, Accessed March 2021, ePublication
- US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
- International Journal of Toxicology, May 2011, pages 5S-16S
- Skin Research and Technology, November 2007, pages 417-24
- Journal of the American College of Toxicology, September 1985, pages 223-248
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Occlusive, Texture agent, Solvent
3rd on the list, which puts it at an estimated 5–20% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
Hydration
Anti-Aging
6 scientific references
- Journal of Pharmaceutical Investigation, March 2021, pages 223-231
- International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
- International Journal of Cosmetic Science, August 2016, ePublication
- British Journal of Dermatology, July 2008, pages 23-34
- Journal of Cosmetic Dermatology, June 2007, pages 75-82
- Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
4th on the list, which puts it at an estimated 2–10% of the formula.
2-Methyl-1,3-propanediol
Hydration
3 scientific references
- PubChem, Accessed April 2021, ePublication
- Cosmetic Ingredient Review, June 2018, pages 1-73
- Contact Dermatitis, September 2017, pages 159-162
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Solvent
5th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active
6th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
Soothing
Anti-Aging
Pore Minimizer
15 scientific references
- International Journal of Dermatology, February 2021, pages 166-173
- Biomolecules & Therapeutics, July 2019, pages 562-569
- Experimental Dermatology, February 2019, pages 15-22
- Dermatologic Therapy, September 2017, ePublication
- Journal of Investigative Dermatology, May 2017, page S116
- International Journal of Pharmaceutics, March 2017, pages 158-162
- Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
- Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
- Skin Pharmacology and Physiology, June 2014, pages 311-315
- International Journal of Pharmacy, January 2013, pages 192-201
- Dermatoendrocrinology, July 2012, pages 308-319
- International Journal of Toxicology, September 2005, pages 1-31
- Dermatologic Surgery, July 2005, pages 860-865
- International Journal of Cosmetic Science, October 2004, pages 231-238
- Journal of Cosmetic Dermatology, April 2004, pages 88-93
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Serica (EU)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether
Synthetic polymer
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
pH adjuster
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Polyoxyethylene (24) Polyoxypropylene (13) Decyltetradecyl Ether
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent, Solvent
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-dihydroxypropane
Hydration
4 scientific references
- PubChem Compound Summary, April 2021, ePublication
- SpecialChem, Accessed April 2021, ePublication
- Cosmetic Ingredient Review, June 2018, pages 1-73
- Cosmetics & Toiletries, May 2013, pages 81-86
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Emollient, Occlusive
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagens, hydrolyzates. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of hoofs and horns composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin.
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Soothing
8 scientific references
- PubChem, Accessed May 2021, ePublication
- Cosmetic Ingredient Review, September 2020, pages 1-38
- Experimental Dermatology, August 2014, pages 553-554
- Journal of Investigative Dermatology, August 2011, pages 526-546
- International Journal of Cosmetic Science, December 2006, pages 447-451
- British Journal of Pharmacology, October 2008, issue 4, pages 475-486
- PloS One, May 2008 (ePublication)
- >International Journal of Cosmetic Science, August 2006, pages 447-451
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Exfoliant
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Chondrus Crispus Powder is (carrageenan) the powder obtained from the dried, ground Alga, Chondrus crispus
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Agar
Hydration
5 scientific references
- IOP Conference Series Earth and Environmental Science, February 2020
- Marine Drugs, November 2018, pages 1-41
- International Journal of Innovative Research in Science, Engineering and Technology, February 2018, ePublication
- Carbohydrate Polymers, July 2013, Volume 96, Issue 1, pages 71-81
- Biomedical Materials, November 2008, Volume 3, Number 4
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Texture agent
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cellulose, 2-hydroxyethyl ether
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent, Chelator
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Disodium dihydrogen ethylenediaminetetraacetate
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Texture agent
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol
Synthetic polymer
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Fluorphlogopite, Mg3K[AlF2O(SiO3)3] (synthetic)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Texture agent
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt
Hydration
5 scientific references
- International Journal of Toxicology, 2018, pages 28S-46S
- Food Science and Biotechnology, October 2017, pages 1391-1397
- The Journal of Chemical Physics, June 2015, ePublication
- The American Journal of Clinical Nutrition, September 2004, pages 539-549
- Skin Research and Technology, February 2003, pages 50-58
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
Hydration
Soothing
7 scientific references
- The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
- International Journal of Cosmetic Science, December 2019, pages 534-547
- Journal of Cosmetic Dermatology, January 2019, pages 346-354
- Cosmetic Ingredient Review, March 2018, pages 1-51
- The Journal of Dermatological Treatment, August 2017, pages 173-180
- Journal of Cosmetic Science, August 2011, pages 361-370
- American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycine Soja Peptide is the di-/tri-peptide fraction isolated from Glycine Soja Protein by ultramembrane filtration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
UV filter, Texture agent
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Titanium dioxide (CI 77891)
Anti-Aging
10 scientific references
- Journal of Cosmetic Dermatology, February 2021, pages 532-537
- Frontiers in Bioengineering and Biotechnology, June 2020
- Journal of Nanoparticle Research, March 2020
- Journal of the European Academy of Dermatology and Venereology, November 2019, pages 34-46
- Photodermatology, Photoimmunology and Photomedicine, November 2019, pages 442-446
- Journal of Cosmetic Science, September 2019, pages 223-234
- Materials, July 2019, pages 1-24
- Photodermatology, Photoimmunology, and Photomedicine, April 2011, pages 58-67
- Skin Therapy Letter, July-August 2008, pages 5-7
- Environmental and Health Perspectives, July 2008, pages 893
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Iron Powder is the element consisting of powdered metallic iron
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent, Fragrance / colour
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Mica is a series of silicate minerals of varying chemical composition but with similar physical properties. Mica may have well-defined cleavage and split into very thin sheets.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Texture agent
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Gellan gum
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Antioxidant
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ascorbic acid, monoester with phosphoric acid, magnesium salt (2:3)
Anti-Aging
Hydration
7 scientific references
- International Journal of Biological Macromolecules, January 2021, pages 333-341
- The Journal of Clinical and Aesthetic Dermatology, July 2017, pages 14-17; and July 2010, pages 20-31
- Annals of Dermatology, February 2016, pages 129-132; and August 2015, pages 376-382
- International Journal of Dermatology, January 2014, pages 93-99
- Indian Dermatology Online Journal, April-June 2013, pages 143-146
- Skin Research and Technology, August 2008, pages 376-380
- International Journal of Toxicology, Supplement 24, 2005, pages 51-111
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Soothing, Surfactant, Plant extract
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae
Soothing
Anti-Aging
6 scientific references
- Phytomedicine, April 2018, pages 110–119
- Clinical, Cosmetic, and Investigational Dermatology, August 2017, pages 311–315
- Indian Journal of Pharmaceutical Sciences, Jan-Feb 2016, pages 27–33
- Postepy Dermatologii I, February 2013, pages 46–49
- Indian Journal of Pharmaceutical Sciences, 2010, pages 546–556
- Scientific Reports, June 2021, ePublication
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Plant extract
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Houttuynia Cordata Extract is an extract of the herb, Houttuynia cordata, Saururaceae
Anti-Aging
Soothing
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Exfoliant, Texture agent
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tin dioxide (CI 77861)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
Hydration
5 scientific references
- PLoS One, October 2016, ePublication
- Contact Dermatitis, May 2016, pages 281-288
- International Journal of Toxicology, September 2013, pages 5S-21S
- Personal Care, 2008, pages 1-4
- Cosmetic Science Technology, 2006, pages 1-11
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2,6,10,15,19,23-Hexamethyltetracosane
Hydration
Anti-Aging
9 scientific references
- Cosmetics Ingredient Review, 2019, ePublication
- ACS Open, July 2017, pages 3, 989–3, 996
- Indian Journal of Dermatology, May-June 2016, pages 279-297
- The Journal of Clinical and Aesthetic Dermatology, June 2014, pages 25-32
- Journal of Cosmetic Science, January-February 2013, pages 59-66
- Advances in Food and Nutrition Research, 2012, pages 223-233
- Molecules, January 2009, pages 540-554
- Journal of Investigative Dermatology, November 2006, pages 2, 430-2, 437
- Free Radical Research, April 2002, pages 471-477
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Solvent
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ethanol, 2-(phenylmethoxy)-
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient, Surfactant
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lecithins. The complex combination of diglycerides of fatty acids linked to the choline ester of phosphoric acid
Hydration
5 scientific references
- Cosmetics, November 2020, pages 1-19
- International Journal of Toxicology, September 2020, pages 5S-25S
- Molecules, March 2020, pages 1-9
- Journal of the American Oil Chemists' Society, March 2014, pages 1, 093-1, 101
- Scientia Pharmaceutica, July 2013, pages 1, 151-1, 166
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycosaminoglycans, hydrolyzed
Hydration
Anti-Aging
8 scientific references
- Supercharged Hydration
- How Hyaluronic Acid Benefits Skin
- What is Dehydrated Skin & How to Choose the Best Products
- What Your Moisturizer Must Contain
- Moisturizer Myths You Should Stop Believing Now
- The Benefits of Glycerin in Skin Care
- The Best Face Oils for Skin
- How Facial Oils Help Skin
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
Hydration
Anti-Aging
Soothing
5 scientific references
- Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
- Journal of Cosmetic Dermatology, July 2014, pages 277-287
- Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
- DermatoEndocrinology, July-December 2012, pages 253-258
- Journal of Drugs in Dermatology, September 2011, pages 990-1000
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octane-1,2-diol
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lecithins, hydrogenated
Hydration
4 scientific references
- International Journal of Toxicology, September 2020, pages 5S-25S
- Nanocosmetics, June 2019, pages 95–140
- Current Drug Delivery, 2016, pages 111–120
- Pharmaceutical Research, February 2013, pages 538–55
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Decanoic acid, ester with 1,2,3-propanetriol octanoate;
Glycerides, mixed decanoyl and octanoyl
Hydration
5 scientific references
- International Journal of Toxicology, September 2020, pages 34-35
- Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
- International Journal of Toxicology, January 2003, pages 4-5
- Food and Chemical Toxicology, January 2000, pages 79-98
- Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-121 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Collagen alpha-1(XXI) chain used such or adapted to the production host. It contains a maximum of 957 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
Anti-Aging
Soothing
3 scientific references
- Cosmetics, November 2020, pages 1–15
- Antioxidants, February 2020, pages 1–17
- Journal of Cosmetic Dermatology, December 2019, pages 1, 693–1, 699
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sodium N-methyl-N-(1-oxohexadecyl)aminoacetate
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Antioxidant
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E
Anti-Aging
Evens Skin Tone
Soothing
4 scientific references
- Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
- Journal of Investigative Dermatology, November 2001, pages 1212-1217
- Canadian Family Physician, July 2006, pages 855-856
- Dermatologic Surgery, April 1999, pages 311-315
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium salt, polymer with 1,1'-sulfonylbis[ethene]
Hydration
Anti-Aging
Soothing
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
L-Glutamine, N-acetyl-
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Antioxidant, Peptide, Preservative
45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Caffeoyl Hexapeptide-65 is the product obtained by the reaction of Caffeic Acid and Hexapeptide-65
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Heptasodium Hexacarboxymethyl Dipeptide-12 is the sodium salt of Hexacarboxymethyl Dipeptide-12. It conforms to the formula:
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Plant extract
48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Bacillus/Soybean/Folic Acid Ferment Extract is the extract of the product obtained by the fermentation of folic acid and Glycine Soja (Soybean) by the microorganism, Bacillus
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
49th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
CI 77480
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
pH adjuster
50th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sodium dihydrogenorthophosphate
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant
51st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagens. A fibrous protein comprising one third of the total protein in mammalian organisms. It is a polypeptide containing three peptide chains and rich in proline and hydroxyproline
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive
52nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, 2-hydroxy-3-(N,N,N-trimethylammonio)propyl chloride derivatives
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
53rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Dextran
Hydration
1 scientific reference
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Preservative, pH adjuster
54th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Benzoic acid
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Preservative
55th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sodium benzoate
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient
56th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Elastin is the hydrolysate of elastin derived by acid, enzyme or other method of hydrolysis
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
57th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Myristoyl Pentapeptide-17 is the product of the reaction of myristic acid and Pentapeptide-17.
Hydration
Soothing
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
58th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Myristoyl Pentapeptide-3 is the reaction product of Myristic Acid with a synthetic peptide containing Threonine, Serine and lysine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
59th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-123 is a single chain recombinant human peptide, produced by fermentation in Pichia pastoris. The starting gene is synthesized to be similar to the human gene which codes for Collagen Alpha-1 (III) Chain used as such or adapted to the production host. It contains a maximum of 1466 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of all or part of the 20 standard amino acids.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
60th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycine, synthetic pentapeptide with leucine, phenylalanine and tyrosine, hexadecanoyl derivatives
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Peptide
61st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl Tetrapeptide-3 is product obtained by the acetylation of Tetrapeptide-3
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Plant extract
62nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Trifolium Pratense Flower Extract is an extract of the flowers of the Red Clover, Trifolium pratense L., Fabaceae
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
63rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Copper Tripeptide-1 is a copper complex of Tripeptide-1
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
64th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lysine, synthetic pentapeptide with serine, and threonine, hexadecanoyl derivatives
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active, Peptide
65th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues
Anti-Aging
Hydration
6 scientific references
- Cosmetics, November 2020, Issue 7, Volume 4, page 91
- La Clinica Terapeutica, November 2020, pages e539-e548
- https://wwwcir-safetyorg/sites/default/files/AcetylHexapeptide-8pdf
- Cutaneous and Ocular Toxicology, March 2015, pages 46-52
- European Journal of Pharmaceutical Sciences, February 2015, pages 27-35
- Dermatologic Therapy, September-October 2007, issue 5, pages 343-349
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
66th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid
Anti-Aging
Hydration
5 scientific references
- Journal of Evidence-Based, Complementary and Alternative Medicine, October 2017, pages 816-823
- Journal of Medicinal Food, October 2016, pages 1, 172-1, 179
- Nutrition Journal, July 2013, ePublication
- Journal of Drugs in Dermatology, 2011, issue 9, pages 990-1000
- Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38-43
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
67th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Palmitoyl Tetrapeptide-7 is the reaction product of palmitic acid and Tetrapeptide-7
Anti-Aging
5 scientific references
- Cosmetics, November 2020, ePublication
- International Journal of Toxicology, Volume 37, Supplement 3, November 2018, pages 90S–102S
- Journal of Cosmetic Dermatology, June 2015, pages 152–160
- Molecular Pharmaceutics, March 2013, pages 1, 063-1, 069
- Plastic Surgical Nursing, April 2012, pages 71–72
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Antioxidant, Peptide, Chelator, pH adjuster
68th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Decapeptide-7 is a single chain recombinant human peptide, produced synthetically to be identical to the protein, Enkephalin. It contains 10 amino acids consisting of glycine, leucine, lysine, phenylalanine, serine, threonine and tyrosine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Antioxidant, Peptide, Chelator
69th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
SH-Octapeptide-4 is a recombinant human peptide produced synthetically to be identical to the protein, Enkephalin. It contains 8 amino acids consisting of glycine, histidine, leucine, lysine, phenylalanine, and tyrosine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Occlusive, Peptide
70th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Oligopeptide-9 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Enkephalin which contains a maximum of 267 amino acids. This protein contains 11 amino acids consisting of arginine, glutamic acid, glutamine, glycine, leucine, methionine, phenylalanine, and tyrosine and may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the 20 standard amino acids
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
71st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Pentapeptide-19 is a recombinant human peptide produced synthetically to be identical to the protein, Enkephalin. It contains 5 amino acids consisting of arginine, glycine, leucine, lysine, phenylalanine, proline and tyrosine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
72nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl-
Anti-Aging
4 scientific references
- International Journal of Toxicology, November 2018, pages 90S-102S
- Cosmetics, May 2017, pages 1-14
- Experimental and Therapeutic Medicine, August 2016, pages 1, 171-1, 176
- International Journal of Cosmetic Science, June 2000, pages 207-218
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
73rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sodium Acetylhyaluronate
Hydration
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
74th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tripeptide-32 is the synthetic peptide consisting of proline, serine and threonine
Anti-Aging
Hydration
8 scientific references
- 5 Super Anti-Aging Antioxidants Your Skin Needs
- How to Keep Your Neck & Chest Looking Young
- Acne & Aging Skin
- How to Diminish Uneven Skin Tone and Get Your Glow Back
- What Are Peptides and What Do They Do for Skin?
- The Truth About Firming Creams
- Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
- Anti-Aging Superstars
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
75th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tetrapeptide-39 Hexapeptide-40 Nonapeptide-20 sr-Spider Polypeptide-3 Decapeptide-30 is a single chain recombinant fusion peptide, produced by fermentation in Lactobacillus The starting gene is synthesized by the fusion of the gene from sr-Spider Polypeptide-3, Tetrapeptide-39, Hexapeptide-40, Nonapeptide-20, and Decapeptide-30. The fusion peptide contains 134 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
76th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Epidermal Growth Factor. It contains a maximum of 53 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
77th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-1 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Basic Fibroblast Growth Factor used as such or adapted to the production host. It contains a maximum of 288 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
78th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
It is a single chain recombinant human peptide,produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Insulin-Like Growth Factor used as such or adapted to the production host.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
79th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-11 is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Acidic Fibroblast Growth Factor 1 used as such or adapted to the production host. It contains a maximum of 155 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
80th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
It is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Vascular Endothelial Growth Factor A used as such or adapted to the production host.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
81st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
PGF,PLGF
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
82nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-22 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Transforming Growth Factor Beta 1. It contains a maximum of 390 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
83rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
It is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Keratinocyte Growth Factor used as such or adapted to the production host.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
84th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
It is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Transforming Growth Factor Alpha used as such or adapted to the production host.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Antioxidant, Peptide
85th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hepatocyte Growth Factor