Centellian24 PDRN Firming Boosting Ampoule

Centellian24

PDRN Firming Boosting Ampoule

face neck ampoule

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Fit by skin type

General, ingredient-based — not your personalized match.

Dry
59%
Combination (dry)
59%
Balanced
89%
Combination (oily)
81%
Oily
81%

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52
Ingredients
7
Benefits
4
Actives
Find Dupes

The Centellian24 PDRN Firming Boosting Ampoule is a high-performance, elasticizing treatment designed to restore sagging skin and enhance facial contours. This advanced formula features PDRN (Polydeoxyribonucleotide), a premium ingredient traditionally used in professional skin treatments, to support skin repair and healthy cellular turnover. Centellian24’s unique formulation combines this with their signature TECA (Titrated Extract of Centella Asiatica) to provide dual benefits: intensive firming and deep soothing. The ampoule's "Boosting" technology ensures that the active nutrients penetrate efficiently, targeting areas prone to loss of volume and fine lines. By reinforcing the skin's core elasticity, it leaves the complexion looking visibly lifted, tighter, and more resilient with a radiant, healthy glow.

Key Insights

Benefits

7
Anti-Acne
Anti-Aging
Evens Skin Tone
Hydration
Oil Control
Pore Minimizer
Soothing

Active Ingredients

4
Ceramides Retinoids Signal peptides Vitamin B3 (niacinamide)

Risks

3
Pregnancy Unsafe
Silicone
Synthetic polymer

About PDRN Firming Boosting Ampoule

Overview

PDRN Firming Boosting Ampoule is a lightweight ampoule from Centellian24. The formula is built mainly around hydration. The ingredient list runs to 52 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Silicones in the formula tend to give a smooth, blurred finish and help it grip under makeup. Hydration is handled by Glycerin, Propanediol and Butylene Glycol, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: Very high. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Propanediol, Butylene Glycol and Methylpropanediol.

Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Calendula Officinalis Flower Oil, Niacinamide, Lactobacillus Ferment and Adenosine.

Who it suits

On richness alone it suits Balanced skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on antioxidant protection and cell renewal. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • 5 ingredients could feed malassezia (fungal acne)
  • Contains ingredients usually flagged for review during pregnancy

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin

May suit

  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 25 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 8 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 5 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Oil Control 2 ingredients

    Regulates sebum production to reduce shine and greasiness

  • Pore Minimizer 2 ingredients

    Tightens and refines the look of enlarged pores

  • Anti-Acne 1 ingredient

    Targets breakouts by reducing bacteria and unclogging pores

  • Evens Skin Tone 1 ingredient

    Brightens and balances complexion for a more uniform appearance

Does not target

Blackhead Reducing Dark Spot Fading Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

2nd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

3rd on the list, which puts it at an estimated 5–20% of the formula.

1,3-dihydroxypropane

Hydration

4th on the list, which puts it at an estimated 2–10% of the formula.

Bis-Peg-18 Methyl Ether Dimethyl Silane is a dimethyl silane ethoxylated methyl diether containing an average of 36 moles of ethylene oxide

Hydration

5th on the list, which puts it at an estimated 2–10% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration

6th on the list, which puts it at an estimated 2–10% of the formula.

2-Methyl-1,3-propanediol

Hydration

8th on the list, which puts it at an estimated 1–5% of the formula.

Poly(oxy-1,2-ethanediyl)], .alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxy-

Hydration
Niacinamide Vitamin B3 (niacinamide)

9th on the list, which puts it at an estimated 1–5% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

10th on the list, which puts it at an estimated 1–5% of the formula.

Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-d-glucopyranoside (4:1)

Hydration

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

alpha-D-Glucopyranoside, beta-D-fructofuranosyl O-alpha-D-galactopyranosyl-

Hydration

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Dihydroxypentane

Hydration

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

alpha-D-Glucopyranoside, alpha-D-glucopyranosyl

Hydration

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration Very high

Ingredients that pull and hold water in the upper layers of skin

Barrier support Low

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control Low

Ingredients that moderate sebum or absorb shine

Brightening Low

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Moderate

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling Low

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (4)

Supporting ingredients (48)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Glycerin Propanediol Bis-peg-18 Methyl Ether Dimethyl Silane Butylene Glycol Methylpropanediol Dipropylene Glycol Glycereth-26 Methyl Gluceth-20 1,2-hexanediol Raffinose Pentylene Glycol Trehalose Dimethicone/vinyl Dimethicone Crosspolymer Diglycerin Dimethiconol Trisiloxane Sodium DNA Lactobacillus Ferment Acrylates/c10-30 Alkyl Acrylate Crosspolymer Curcuma Longa Root Extract Tromethamine Glyceryl Polymethacrylate Dioscorea Japonica Root Extract Ethylhexylglycerin Glycosyl Trehalose Sodium Polyacrylate Pvm/ma Copolymer Hydrogenated Lecithin Hydrolyzed Collagen Hydrogenated Starch Hydrolysate Xanthan Gum Adenosine Dextrin Theobroma Cacao Seed Extract Hydrolyzed Elastin Sucrose Distearate Lecithin Carbomer Polyquaternium-51 Polysorbate 20 Glyceryl Stearate BHT Cyanocobalamin Biosaccharide Gum-1 Tocopherol Carnosine Calendula Officinalis Flower Oil

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • Oil-free
  • No animal-derived ingredients

Contains

  • Silicones

    Dimethicone/vinyl Dimethicone Crosspolymer, Dimethiconol, Trisiloxane

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Retinoids (retinol, retinal)
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • AHAs (glycolic, lactic)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • BHA (salicylic acid)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • PHAs (gluconolactone)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Benzoyl peroxide

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Vitamin C (L-ascorbic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • Azelaic acid

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Treat" step.

  • Apply to clean, dry skin and give it a minute to absorb before the next layer.
  • Introduce one new treatment at a time so you can identify what is working.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Contains Retinol, usually reviewed with a doctor during pregnancy.
Fungal acne (malassezia)
5 ingredients could feed malassezia: Lactobacillus Ferment, Sucrose Distearate, Polysorbate 20, Glyceryl Stearate, Calendula Officinalis Flower Oil. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Pregnancy Unsafe, Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 52 ingredients on the label.

14
Texture agent

Sets the thickness, spread and stability of the formula

10
Humectant

Draws water into the upper layers of skin

9
Solvent

Dissolves and carries everything else

8
Emollient

Softens and smooths by filling gaps between skin cells

7
Occlusive

Forms a film that slows water loss

7
Surfactant

Lifts oil and dirt, or holds oil and water together

4
Active

Changes how skin behaves rather than how it feels

3
Antioxidant

Neutralises free radicals from UV and pollution

3
Plant extract

Botanical material, usually for antioxidants or scent

1
Peptide

Amino-acid chains that signal for repair or firmness

1
pH adjuster

Sets the acidity the formula needs to work

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Glycerin Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
3 Propanediol Texture agent
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

1,3-dihydroxypropane

Hydration
4 scientific references
  • PubChem Compound Summary, April 2021, ePublication
  • SpecialChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Cosmetics & Toiletries, May 2013, pages 81-86
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Emollient, Surfactant, Solvent

4th on the list, which puts it at an estimated 2–10% of the formula.

Bis-Peg-18 Methyl Ether Dimethyl Silane is a dimethyl silane ethoxylated methyl diether containing an average of 36 moles of ethylene oxide

Hydration
3 scientific references
  • https://cosmeticsspecialchemcom/inci-ingredients/bis-peg-18-methyl-ether-dimethyl-silane
  • International Journal of Toxicology, September-October 2013, pages 56S-64S
  • https://wwwcosmeticsandtoiletriescom/formulating/function/feelenhancer/112899654html
5 Butylene Glycol Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

5th on the list, which puts it at an estimated 2–10% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

6th on the list, which puts it at an estimated 2–10% of the formula.

2-Methyl-1,3-propanediol

Hydration
3 scientific references
  • PubChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Contact Dermatitis, September 2017, pages 159-162
7 Dipropylene Glycol Texture agent
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

7th on the list, which puts it at an estimated 1–5% of the formula.

1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol

8 Glycereth-26 Humectant
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent

8th on the list, which puts it at an estimated 1–5% of the formula.

Poly(oxy-1,2-ethanediyl)], .alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxy-

Hydration
2 scientific references
  • Nanomedicine: Nanotechnology, Biology and Medicine, February 2020, ePublication
  • Cosmetic Ingredient Review, March 2019, pages 1-11
9 Niacinamide Active
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

9th on the list, which puts it at an estimated 1–5% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
10 Methyl Gluceth-20 Humectant
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant

10th on the list, which puts it at an estimated 1–5% of the formula.

Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-d-glucopyranoside (4:1)

Hydration
2 scientific references
  • International Journal of Toxicology, Supplement, November 2016, pages 12S–40S
  • https://wwwlubrizolcom/Personal-Care/Products/Product-Finder/Products-Data/Glucam-E-20-humectant
11 1,2-hexanediol Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

alpha-D-Glucopyranoside, beta-D-fructofuranosyl O-alpha-D-galactopyranosyl-

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Dihydroxypentane

Hydration
4 scientific references
  • https://thedermreviewcom/pentylene-glycol/
  • Regulatory Toxicology and Pharmacology, July 2017, pages 106-111
  • Prospector, June 2015, ePublication
  • International Journal of Toxicology, October 2012, pages 147S-168S
14 Trehalose Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

alpha-D-Glucopyranoside, alpha-D-glucopyranosyl

Hydration
7 scientific references
  • Cosmetics, October 2019, pages 1-10
  • Cell Death & Disease, July 2019, pages 1-16
  • International Journal of Toxicology, 2019, pages 5S-38S
  • Applied Microbiology and Biotechnology, February 2018, pages 2, 965-2, 976
  • Journal of Applied Polymer Science, May 2017, pages 1-6
  • Biomedical Reports, September 2014, pages 755-759
  • Journal of Pharmaceutical Sciences, June 2011, pages 2, 020-2, 053
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dimethicone/Vinyl Dimethicone Crosspolymer is a crosslinked dimethyl siloxane polymer (silicone elastomer) that is formed by the reaction between Hydrogen Dimethicone or Bis-Hydrogen Dimethicone, and Vinyl Dimethicone or Bis-Vinyldimethicone.

Silicone
16 Diglycerin Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Oxybispropanediol

Hydration
17 Dimethiconol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Emollient

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Poly[oxy(dimethylsilylane)], .alpha.-hydro-.omega.-hydroxy-

Hydration
3 scientific references
  • CosmeticsInfoorg, Accessed September 2021, ePublication
  • International Journal of Toxicology, November 2017, pages 31S-50S
  • International Journal of Cosmetic Science, April 2005, page 139
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Trisiloxane, Octamethyl-

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Deoxyribonucleic acid, sodium salts

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lactobacillus Ferment is the product obtained from the fermentation of Lactobacillus.

Hydration Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Curcuma Longa Root Extract is an extract of the rhizomes of the Turmeric, Curcuma longa L., Zingiberaceae

23 Ceramide NP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Hydration Anti-Aging
11 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
24 Tromethamine pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, 2-methyl-, homopolymer, ester with 1,2,3-propanetriol

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dioscorea Japonica Root Extract is an extract of the roots of Dioscorea japonica, Dioscoreaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycosyl Trehalose is the product obtained by the reaction forming a-1,1-glucosidic linkage with glucosyltransferase in reducing end side of hydrolysed starch

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Occlusive, Texture agent

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, homopolymer, sodium salt

Oil Control Synthetic polymer
7 scientific references
  • International Food Research Journal, February 2021, pages 44 - 55
  • Journal of Nanoscience and Nanotechnology, March 2018, pages 1, 611-1, 614
  • Industrial & Engineering Chemistry Research, November 2014, pages 18, 346-18, 351
  • Journal of Applied Polymer Science, November 2001, pages 1, 515-1, 520
  • United States Patent, April 2000, ePublication
  • https://wwwsocochemcom/is-sodium-polyacrylate-safehtml
  • https://wwwcir-safetyorg/sites/default/files/acryco092018TARpdf
30 Pvm/ma Copolymer Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,5-Furandione, polymer with methoxyethene; copolymer of methyl vinyl ether and maleic anhydride

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, hydrogenated

Hydration
4 scientific references
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Nanocosmetics, June 2019, pages 95–140
  • Current Drug Delivery, 2016, pages 111–120
  • Pharmaceutical Research, February 2013, pages 538–55
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Emollient, Occlusive

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Collagens, hydrolyzates. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of hoofs and horns composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin.

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Maize starch, hydrolyzed, hydrogenated

Hydration
2 scientific references
  • Roquettecom, Accessed March 2021, ePublication
  • Cosmetic Ingredient Review, October 2015, pages 1-87
34 Xanthan Gum Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant, Texture agent

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Xanthan gum

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
36 Dextrin Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dextrin

Oil Control
8 scientific references
  • Oil-Absorbing Ingredients
  • Help for Oily Skin
  • Salicylic Acid for Skin
  • How BHA Exfoliants Work
  • Which BHA Exfoliant is Right for Me?
  • Niacinamide Benefits: What Does Niacinamide Do for Skin?
  • The Best Toners for Oily Skin
  • The Best Moisturizers for Oily, Acne-Prone Skin
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant, Plant extract

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Theobroma Cacao Seed Extract is the extract of the seeds of the Cocoa, Theobroma cacao L., Sterculiaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydrolyzed Elastin is the hydrolysate of elastin derived by acid, enzyme or other method of hydrolysis

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sucrose distearate

40 Lecithin Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins. The complex combination of diglycerides of fatty acids linked to the choline ester of phosphoric acid

Hydration
5 scientific references
  • Cosmetics, November 2020, pages 1-19
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Molecules, March 2020, pages 1-9
  • Journal of the American Oil Chemists' Society, March 2014, pages 1, 093-1, 101
  • Scientia Pharmaceutica, July 2013, pages 1, 151-1, 166
41 Carbomer Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether

Synthetic polymer
42 Polyquaternium-51 Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-(N,N,N-Trimethylamino)ethyl 2-(2-methyl-2-propenoyloxy)ethyl phosphate inner salt, polymer with butyl 2-methyl-2-propenoate

Hydration
43 Polysorbate 20 Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.

44 Glyceryl Stearate Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Stearic acid, monoester with glycerol

Hydration
3 scientific references
  • Cosmeticsinfoorg, Accessed November 2021, ePublication
  • Drugs in Context, April 2018, pages 1-14
  • International Journal of Toxicology, May 2007, pages 1–30
45 BHT Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,6-Di-tert-butyl-p-cresol

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cyanocobalamin; Vitamine B12

Anti-Aging
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Biosaccharide Gum-1 is a fermentation gum derived from sorbitol. It is described as a polymer of α-L-fucose-1|->|3-α- D-galactose-1|->|3-α-D-galacturonic acid trisaccharides

Hydration Soothing
48 Tocopherol Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E

Anti-Aging Evens Skin Tone Soothing
4 scientific references
  • Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
  • Journal of Investigative Dermatology, November 2001, pages 1212-1217
  • Canadian Family Physician, July 2006, pages 855-856
  • Dermatologic Surgery, April 1999, pages 311-315
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Peptide

49th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lysine, synthetic pentapeptide with serine, and threonine, hexadecanoyl derivatives

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

50th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

L-histidine, N-beta-alanyl

Anti-Aging
9 scientific references
  • BMJ Open, December 2020, pages 1-12
  • Oxidative Medicine and Cellular Longevity, September 2020, pages 1-15
  • Cosmetics, November 2018, pages 1-9
  • Aging and Disease, October 2015, pages 369-379
  • The Journal of Dermatological Treatment, October 2012, pages 345-384
  • Biopolymers, January 2008, pages 655-662
  • Journal of Cosmetic Dermatology, July 2004, pages 26-34
  • Life Sciences, March 2002, pages 1789-1799
  • FEBS Letters, July 1995, pages 81-85
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

51st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Calendula Officinalis Flower Oil is the oil derived from the flowers of the Calendula, Calendula officinalis L., Compositae

52 Retinol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

52nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Retinol; vitamin A

Anti-Aging Anti-Acne Pore Minimizer Pregnancy Unsafe
10 scientific references
  • Journal of Drugs in Dermatology, September 2019, pages 918-923; and March 2015, pages 271-280
  • Experimental Dermatology, August 2019, pages 906-913
  • Archives of Dermatological Research, May 2017, pages 275-283
  • International Journal of Cosmetic Science, February 2017, pages 56-65
  • Dermatology, May 2014, pages 314-325
  • Dermatoendocrinology, July 2012, issue 3, pages 308-319
  • Toxicological Research, March 2010, pages 61-66
  • Archives of Dermatology, May 2007, pages 606-612
  • The Journal of Pathology, January 2007, issue 2, pages 241-251
  • Clinical Interventions in Aging, December 2006, pages 327-348

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Frequently asked questions

What ingredients are in PDRN Firming Boosting Ampoule?

WATER, GLYCERIN, PROPANEDIOL, BIS-PEG-18 METHYL ETHER DIMETHYL SILANE, BUTYLENE GLYCOL, METHYLPROPANEDIOL, DIPROPYLENE GLYCOL, GLYCERETH-26, NIACINAMIDE, METHYL GLUCETH-20, 1,2-HEXANEDIOL, RAFFINOSE, PENTYLENE GLYCOL, TREHALOSE, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, DIGLYCERIN, DIMETHICONOL, TRISILOXANE, SODIUM DNA, LACTOBACILLUS FERMENT, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, CURCUMA LONGA ROOT EXTRACT, CERAMIDE NP, TROMETHAMINE, GLYCERYL POLYMETHACRYLATE, DIOSCOREA JAPONICA ROOT EXTRACT, ETHYLHEXYLGLYCERIN, GLYCOSYL TREHALOSE, SODIUM POLYACRYLATE, PVM/MA COPOLYMER, HYDROGENATED LECITHIN, HYDROLYZED COLLAGEN, HYDROGENATED STARCH HYDROLYSATE, XANTHAN GUM, ADENOSINE, DEXTRIN, THEOBROMA CACAO SEED EXTRACT, HYDROLYZED ELASTIN, SUCROSE DISTEARATE, LECITHIN, CARBOMER, POLYQUATERNIUM-51, POLYSORBATE 20, GLYCERYL STEARATE, BHT, CYANOCOBALAMIN, BIOSACCHARIDE GUM-1, TOCOPHEROL, PALMITOYL PENTAPEPTIDE-4, CARNOSINE, CALENDULA OFFICINALIS FLOWER OIL, RETINOL.

What are the active ingredients in PDRN Firming Boosting Ampoule?

NIACINAMIDE, CERAMIDE NP, PALMITOYL PENTAPEPTIDE-4, RETINOL.

How do I use PDRN Firming Boosting Ampoule?

At the final step of your skincare routine, take an appropriate amount and gently massage it into your face and neck. Use morning and/or evening as needed. Tip: Apply it when your skin is slightly damp (after toner or essence) to help lock in moisture more effectively. Start with a thin layer, and increase slightly in colder or drier weather for added protection.

What skin types is PDRN Firming Boosting Ampoule good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is PDRN Firming Boosting Ampoule good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is PDRN Firming Boosting Ampoule fungal acne safe?

5 ingredients could feed malassezia: Lactobacillus Ferment, Sucrose Distearate, Polysorbate 20, Glyceryl Stearate, Calendula Officinalis Flower Oil. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use PDRN Firming Boosting Ampoule while pregnant?

It contains Retinol, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.

Is PDRN Firming Boosting Ampoule fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does PDRN Firming Boosting Ampoule contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is PDRN Firming Boosting Ampoule silicone free?

No — it contains Dimethicone/vinyl Dimethicone Crosspolymer, Dimethiconol, Trisiloxane.

Does PDRN Firming Boosting Ampoule contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is PDRN Firming Boosting Ampoule paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with PDRN Firming Boosting Ampoule?

It layers well with Retinoids (retinol, retinal), Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides. Take more care combining it with AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide, Vitamin C (L-ascorbic acid), Azelaic acid — use them in separate routines or on alternate days.

When should I apply PDRN Firming Boosting Ampoule?

Use it morning and evening, after toner, before moisturiser.

How many ingredients does PDRN Firming Boosting Ampoule have?

It lists 52 ingredients, of which 4 are recorded as actives.

Who makes PDRN Firming Boosting Ampoule?

Centellian24.

Brand
Centellian24

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