ma:nyo Glutathione 7 Dark Spot Serum Patch

ma:nyo

Glutathione 7 Dark Spot Serum Patch

face patch

Added Last edited

Fit by skin type

General, ingredient-based — not your personalized match.

Dry
54%
Combination (dry)
54%
Balanced
84%
Combination (oily)
86%
Oily
86%

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47
Ingredients
7
Benefits
4
Actives
Find Dupes

Target dark spots with ma:nyo Glutathione 7 Dark Spot Serum Patch, brightening patches that help improve uneven skin tone and discoloration. Give stubborn spots a little extra attention with patches that sit comfortably over areas you want to target. Made with Glutathione, Niacinamide, Arbutin, Alpha-Arbutin, Kojic Acid, and Ascorbic Acid, the formula focuses on brighter, more even-looking skin. Multiple forms of Hyaluronic Acid add hydration, while Centella Asiatica Extract, Panthenol, and Allantoin help keep skin feeling comfortable while you wear them.

Key Insights

Benefits

7
Anti-Aging
Dark Spot Fading
Evens Skin Tone
Hydration
Oil Control
Pore Minimizer
Soothing

Active Ingredients

4
Hyaluronic acid Vitamin B3 (niacinamide) Vitamin B5 (panthenol) Vitamin C

Risks

1
Synthetic polymer

About Glutathione 7 Dark Spot Serum Patch

Overview

Glutathione 7 Dark Spot Serum Patch is a lightweight patch from ma:nyo. The formula is built mainly around hydration. The ingredient list runs to 47 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Hydration is handled by Glycerin, Butylene Glycol and Propanediol, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: Very high. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Butylene Glycol, Propanediol and Ethylhexylglycerin.

Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Allantoin, Panthenol, Centella Asiatica Extract and Niacinamide.

Brightening: Moderate. Ingredients that act on uneven tone and post-inflammatory marks, and here that comes from Niacinamide, Dipotassium Glycyrrhizate, Arbutin and Alpha-arbutin.

Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Panthenol and Squalane.

Who it suits

On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on cell renewal and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, silicone-free and microplastic-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

Use it in the evening. In a routine it goes on affected areas only, after serums. Keep it to the spot itself — treating clear skin buys irritation, not results.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • Silicone-free
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • One ingredient could feed malassezia (fungal acne)
  • Contains ingredients usually flagged for review during pregnancy

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin
  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 21 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 15 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 10 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Dark Spot Fading 5 ingredients

    Fades hyperpigmentation and evens out dark spots over time

  • Evens Skin Tone 5 ingredients

    Brightens and balances complexion for a more uniform appearance

  • Oil Control 1 ingredient

    Regulates sebum production to reduce shine and greasiness

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

Does not target

Anti-Acne Blackhead Reducing Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

2nd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

3rd on the list, which puts it at an estimated 5–20% of the formula.

2-propenoic acid, 2-methyl-, polymer with ethyl 2-propenoate and methyl 2-methyl-2-propenoate

Hydration
Niacinamide Vitamin B3 (niacinamide)

4th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

5th on the list, which puts it at an estimated 2–10% of the formula.

Carrageenan Carrageenin Chondrus Chondrus Crispus (Carrageenan)

Hydration

6th on the list, which puts it at an estimated 2–10% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glucomannan is the polymer of Mannose containing side chains of glucose

Hydration

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone

Anti-Aging Hydration

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urea, (2,5-dioxo-4-imidazolidinyl)-

Soothing

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-dihydroxypropane

Hydration

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sucrose

Hydration

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt

Soothing Dark Spot Fading

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration Very high

Ingredients that pull and hold water in the upper layers of skin

Barrier support Moderate

Lipids and repair signals that support skin barrier integrity

Antioxidant support Low

Ingredients that mop up free radicals from UV and pollution

Oil control Moderate

Ingredients that moderate sebum or absorb shine

Brightening Moderate

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Moderate

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Supporting ingredients (38)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Glycerin Acrylates Copolymer Carrageenan Butylene Glycol 1,2-hexanediol Glucomannan Hydroxyacetophenone Cellulose Gum Calcium Chloride Ceratonia Siliqua Gum Allantoin Gardenia Florida Fruit Extract Polyglyceryl-10 Laurate Potassium Chloride Propanediol Cyamopsis Tetragonoloba Gum Sucrose Dipotassium Glycyrrhizate Dextrin Adenosine Caprylyl Glycol Arginine Ethylhexylglycerin Sodium Phytate Sphingomonas Ferment Extract Glutathione Phosphatidylcholine Squalane Acetyl Glucosamine Arbutin Alpha-arbutin Kojic Acid Centella Asiatica Extract Citrus Limon Fruit Extract Hydroxypropyltrimonium Hyaluronate Tocopheryl Acetate Hydrolyzed Sodium Hyaluronate

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Silicone-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • Oil-free
  • No animal-derived ingredients

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Vitamin C (L-ascorbic acid)
  • PHAs (gluconolactone)
  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • Benzoyl peroxide

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Retinoids (retinol, retinal)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • AHAs (glycolic, lactic)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • BHA (salicylic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Evening
  1. Cleanse
  2. Toning
  3. Spot treat
  4. Moisturise

This product is the "Spot treat" step.

  • Keep it to the spot itself — treating clear skin buys irritation, not results.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Contains Arbutin, Alpha-arbutin, Kojic Acid, usually reviewed with a doctor during pregnancy.
Fungal acne (malassezia)
1 ingredient could feed malassezia: Polyglyceryl-10 Laurate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 47 ingredients on the label.

10
Texture agent

Sets the thickness, spread and stability of the formula

9
Active

Changes how skin behaves rather than how it feels

9
Humectant

Draws water into the upper layers of skin

8
Occlusive

Forms a film that slows water loss

6
Antioxidant

Neutralises free radicals from UV and pollution

5
Solvent

Dissolves and carries everything else

4
Plant extract

Botanical material, usually for antioxidants or scent

3
Soothing

Calms visible redness and irritation

3
Emollient

Softens and smooths by filling gaps between skin cells

2
Surfactant

Lifts oil and dirt, or holds oil and water together

1
Chelator

Binds trace metals that would otherwise spoil the formula

1
pH adjuster

Sets the acidity the formula needs to work

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Glycerin Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Occlusive, Texture agent

3rd on the list, which puts it at an estimated 5–20% of the formula.

2-propenoic acid, 2-methyl-, polymer with ethyl 2-propenoate and methyl 2-methyl-2-propenoate

Hydration Synthetic polymer
3 scientific references
  • CosmeticsInfoorg, Accessed October 2021, ePublication
  • Cosmetic Ingredient Review, January 2019, pages 1-42
  • Swiss Society of Chemists, September 2015, ePublication
4 Niacinamide Active
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

4th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line

5th on the list, which puts it at an estimated 2–10% of the formula.

Carrageenan Carrageenin Chondrus Chondrus Crispus (Carrageenan)

Hydration
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
6 Butylene Glycol Humectant
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

6th on the list, which puts it at an estimated 2–10% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

8 Glucomannan Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glucomannan is the polymer of Mannose containing side chains of glucose

Hydration
9 Hydroxyacetophenone Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone

Anti-Aging Hydration
4 scientific references
  • Journal of Oleo Science, February 2019, pages 183-191
  • Applied Environmental Microbiology, June 2018, ePublication
  • Journal of Biosciences, May-June 2004, pages 345-353
  • Scientific Reports, April 2021, pages 1–7
10 Cellulose Gum Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cellulose, carboxymethyl ether, sodium salt

11 Calcium Chloride Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Calcium chloride

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Occlusive, Texture agent

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceratonia Siliqua Gum is the ground seed of the ripe fruit of St. John's Bread (carob), Ceratonia siliqua L. (Locust bean), Leguminosae

13 Allantoin Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Soothing

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urea, (2,5-dioxo-4-imidazolidinyl)-

Soothing
8 scientific references
  • Chemistry Series, March 2020, pages 7-21
  • Molecules, June 2019, pages 1-33
  • European Journal of Pharmacology, February 2018, pages 68-78
  • Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
  • Pharmacognosy Review, Volume 5, July-December 2011
  • International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
  • Journal of Occupational Medicine and Toxicology, October 2008, ePublication
  • https://wwwaccessdatafdagov/scripts/cdrh/cfdocs/cfcfr/CFRSearchcfm?CFRPart=347&showFR=1
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Gardenia Florida Fruit Extract is an extract of the fruit of the Cape Jasmine, Gardenia Florida L., Rubiaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio)

16 Potassium Chloride Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Potassium chloride

17 Propanediol Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Solvent

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-dihydroxypropane

Hydration
4 scientific references
  • PubChem Compound Summary, April 2021, ePublication
  • SpecialChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Cosmetics & Toiletries, May 2013, pages 81-86
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cyamopsis Tetragonoloba Gum is a resinous material derived from the ground endosperm of the Guar, Cyamopsis tetragonoloba L., Leguminosae

19 Sucrose Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Soothing

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sucrose

Hydration
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt

Soothing Dark Spot Fading
8 scientific references
  • How to Care for Red, Sensitive Skin
  • 7 Best Products for Sensitive Skin
  • Skincare Tips for Calming Redness
  • Skin-Soothing Ingredients
  • How the Paula’s Choice CALM Collection Works
  • The Best Moisturizers for Sensitive Skin
  • The Best Ways to Treat Acne and Sensitive Skin
  • Skin Care for Extremely Dry, Sensitive Skin
21 Dextrin Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dextrin

Oil Control
8 scientific references
  • Oil-Absorbing Ingredients
  • Help for Oily Skin
  • Salicylic Acid for Skin
  • How BHA Exfoliants Work
  • Which BHA Exfoliant is Right for Me?
  • Niacinamide Benefits: What Does Niacinamide Do for Skin?
  • The Best Toners for Oily Skin
  • The Best Moisturizers for Oily, Acne-Prone Skin
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
23 Caprylyl Glycol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Octane-1,2-diol

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

L-Arginine

Hydration Anti-Aging
6 scientific references
  • Biobased Surfactants (Second Edition), 2019, pages 413-445
  • Scientific Reports, February 2016, pages 1-10
  • Cosmetic Ingredient Review, October 2012, pages 1-35
  • Journal of Advanced Research, July 2010, pages 169–177
  • International Journal of Cosmetic Science, April 2005, page 139
  • Wound Repair and Regeneration, November-December 2003, pages 419-423
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
26 Panthenol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
27 Sodium Phytate Chelator
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Chelator

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Myo-Inositol, hexakis(dihydrogen phosphate), sodium salt

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sphingomonas Ferment Extract is an extract of the product obtained by the fermentation of Sphingomonas

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycine, N-(N-L-.gamma.-glutamyl-L-cysteinyl)-

Anti-Aging
8 scientific references
  • Journal of Cosmetic Dermatology, June 2019, pages 728–737
  • Clinical Cosmetic and Investigative Dermatology, April 2017, pages 147-153 and October 2014, pages 267-274
  • Nutrients, August 2017, pages 1-27
  • DermatoEndocrinology, July 2012, pages 308-319
  • Journal of Agricultural and Food Chemistry, 2011, pages 3, 940-3, 949
  • The Dermatologist, October 2011, volume 19, issue 10
  • Journal of Dermatologic Science, May 2010, pages 85-90
  • Free Radical Biology and Medicine, October 1994, pages 333-349
30 Phosphatidylcholine Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, egg yolk

Hydration
31 Squalane Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,6,10,15,19,23-Hexamethyltetracosane

Hydration Anti-Aging
9 scientific references
  • Cosmetics Ingredient Review, 2019, ePublication
  • ACS Open, July 2017, pages 3, 989–3, 996
  • Indian Journal of Dermatology, May-June 2016, pages 279-297
  • The Journal of Clinical and Aesthetic Dermatology, June 2014, pages 25-32
  • Journal of Cosmetic Science, January-February 2013, pages 59-66
  • Advances in Food and Nutrition Research, 2012, pages 223-233
  • Molecules, January 2009, pages 540-554
  • Journal of Investigative Dermatology, November 2006, pages 2, 430-2, 437
  • Free Radical Research, April 2002, pages 471-477
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

N-acetyl-.alpha.-D-glucosamine

Hydration Soothing Evens Skin Tone
6 scientific references
  • Cosmetic Ingredient Review, July 2022, pages 1-25
  • International Journal of Pharmaceutics, March 2020, pages 1-10
  • Life Sciences, May 2016, pages 21-29
  • Drug Design, Development and Therapy, August 2014, pages 1, 923-1, 928
  • Journal of Cosmetic Dermatology, June 2013, pages 96-102; and December 2006, pages 309-315
  • Dermato-endocrinology, July 2012, pages 253-258
33 Arbutin Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

4-Hydroxyphenyl-beta-D-glucopyranoside

Dark Spot Fading Evens Skin Tone
34 Alpha-arbutin Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

4-Hydroxyphenyl-alpha-D-glucopyranoside

Anti-Aging Dark Spot Fading Evens Skin Tone
35 Ascorbic Acid Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Antioxidant, pH adjuster

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ascorbic acid

Anti-Aging Dark Spot Fading Evens Skin Tone
12 scientific references
  • Drug Delivery, February 2021, pages 445-453
  • Journal of Cosmetic Dermatology, December 2020, pages 3, 262-3, 269
  • Journal of Oral and Maxillofacial Pathology, May-August 2020, pages 374-382
  • Journal of Cosmetic Dermatology, March 2020, pages 671-676
  • Journal of Clinical and Aesthetic Dermatology, July 2017 pages 14-17
  • Journal of Drugs in Dermatology, July 2016, pages 863-867
  • Clinical, Cosmetic, and Investigational Dermatology, September 2015, pages 463-470
  • Indian Dermatology Online Journal, April-June 2013, pages 143-146
  • AAPS PharmSciTech, July 2011, pages 917-923
  • Journal of Drugs in Dermatology, July 2008, Supplement, pages s2-s6
  • International Journal of Toxicology, Supplement 2, March 2005, pages 51-111
  • Skin Pharmacology and Physiology, July-August 2004, pages 200-206
36 Kojic Acid Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

5-Hydroxy-2-hydroxymethyl-4-pyrone

Dark Spot Fading Evens Skin Tone Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing, Surfactant, Plant extract

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae

Soothing Anti-Aging
6 scientific references
  • Phytomedicine, April 2018, pages 110–119
  • Clinical, Cosmetic, and Investigational Dermatology, August 2017, pages 311–315
  • Indian Journal of Pharmaceutical Sciences, Jan-Feb 2016, pages 27–33
  • Postepy Dermatologii I, February 2013, pages 46–49
  • Indian Journal of Pharmaceutical Sciences, 2010, pages 546–556
  • Scientific Reports, June 2021, ePublication
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Citrus Limon Fruit Extract is an extract of the fruit of the Lemon, Citrus limon (L.), Rutaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, 2-hydroxy-3-(N,N,N-trimethylammonio)propyl chloride derivatives

41 Tocopheryl Acetate Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate

Anti-Aging Soothing
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium Acetylhyaluronate

Hydration Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis

Hydration
44 Hyaluronic Acid Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid

Anti-Aging Hydration
5 scientific references
  • Journal of Evidence-Based, Complementary and Alternative Medicine, October 2017, pages 816-823
  • Journal of Medicinal Food, October 2016, pages 1, 172-1, 179
  • Nutrition Journal, July 2013, ePublication
  • Journal of Drugs in Dermatology, 2011, issue 9, pages 990-1000
  • Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38-43
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium salt, polymer with 1,1'-sulfonylbis[ethene]

Hydration Anti-Aging Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydrolyzed Sodium Hyaluronate is the hydrolysate of Sodium Hyaluronate derived by acid, enzyme or other method of hydrolysis

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, potassium salt

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Frequently asked questions

What ingredients are in Glutathione 7 Dark Spot Serum Patch?

WATER, GLYCERIN, ACRYLATES COPOLYMER, NIACINAMIDE, CARRAGEENAN, BUTYLENE GLYCOL, 1,2-HEXANEDIOL, GLUCOMANNAN, HYDROXYACETOPHENONE, CELLULOSE GUM, CALCIUM CHLORIDE, CERATONIA SILIQUA GUM, ALLANTOIN, GARDENIA FLORIDA FRUIT EXTRACT, POLYGLYCERYL-10 LAURATE, POTASSIUM CHLORIDE, PROPANEDIOL, CYAMOPSIS TETRAGONOLOBA GUM, SUCROSE, DIPOTASSIUM GLYCYRRHIZATE, DEXTRIN, ADENOSINE, CAPRYLYL GLYCOL, ARGININE, ETHYLHEXYLGLYCERIN, PANTHENOL, SODIUM PHYTATE, SPHINGOMONAS FERMENT EXTRACT, GLUTATHIONE, PHOSPHATIDYLCHOLINE, SQUALANE, ACETYL GLUCOSAMINE, ARBUTIN, ALPHA-ARBUTIN, ASCORBIC ACID, KOJIC ACID, CENTELLA ASIATICA EXTRACT, CITRUS LIMON FRUIT EXTRACT, SODIUM HYALURONATE, HYDROXYPROPYLTRIMONIUM HYALURONATE, TOCOPHERYL ACETATE, SODIUM ACETYLATED HYALURONATE, HYDROLYZED HYALURONIC ACID, HYALURONIC ACID, SODIUM HYALURONATE CROSSPOLYMER, HYDROLYZED SODIUM HYALURONATE, POTASSIUM HYALURONATE.

What are the active ingredients in Glutathione 7 Dark Spot Serum Patch?

NIACINAMIDE, PANTHENOL, ASCORBIC ACID, SODIUM HYALURONATE, SODIUM ACETYLATED HYALURONATE, HYDROLYZED HYALURONIC ACID, HYALURONIC ACID, SODIUM HYALURONATE CROSSPOLYMER, POTASSIUM HYALURONATE.

How do I use Glutathione 7 Dark Spot Serum Patch?

Apply your serum first, then take out a patch and tear it to the size you need. Place the patch directly onto the area of concern. Leave on for at least 30 minutes. Tip : For best results, wait until the patch becomes translucent before removing.

What skin types is Glutathione 7 Dark Spot Serum Patch good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is Glutathione 7 Dark Spot Serum Patch good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is Glutathione 7 Dark Spot Serum Patch fungal acne safe?

One ingredient could feed malassezia: Polyglyceryl-10 Laurate. That describes the yeast's food supply, not a prediction that it will cause a breakout.

Can I use Glutathione 7 Dark Spot Serum Patch while pregnant?

It contains Arbutin, Alpha-arbutin, Kojic Acid, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.

Is Glutathione 7 Dark Spot Serum Patch fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does Glutathione 7 Dark Spot Serum Patch contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is Glutathione 7 Dark Spot Serum Patch silicone free?

Yes. Reading the full ingredient list, this formula is silicone-free.

Does Glutathione 7 Dark Spot Serum Patch contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is Glutathione 7 Dark Spot Serum Patch paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with Glutathione 7 Dark Spot Serum Patch?

It layers well with Vitamin C (L-ascorbic acid), PHAs (gluconolactone), Azelaic acid, Copper peptides, Bakuchiol, Niacinamide. Take more care combining it with Benzoyl peroxide, Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid) — use them in separate routines or on alternate days.

When should I apply Glutathione 7 Dark Spot Serum Patch?

Use it in the evening, on affected areas only, after serums.

How many ingredients does Glutathione 7 Dark Spot Serum Patch have?

It lists 47 ingredients, of which 9 are recorded as actives.

Who makes Glutathione 7 Dark Spot Serum Patch?

ma:nyo.

Brand
ma:nyo

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