-
Estimated level
- 30–80%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Solvent
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Hydration
3 scientific references
- Skin Research and Technology, May 2015, pages 131-136
- Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
- Journal of Cosmetic Science, September-October 1993, pages 249-262
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Occlusive, Texture agent, Solvent
2nd on the list, which puts it at an estimated 5–20% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
Hydration
Anti-Aging
6 scientific references
- Journal of Pharmaceutical Investigation, March 2021, pages 223-231
- International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
- International Journal of Cosmetic Science, August 2016, ePublication
- British Journal of Dermatology, July 2008, pages 23-34
- Journal of Cosmetic Dermatology, June 2007, pages 75-82
- Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
-
Estimated level
- 5–20%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Humectant, Texture agent, Solvent
3rd on the list, which puts it at an estimated 5–20% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7)
(R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
Hydration
5 scientific references
- CosmeticsInfoorg, Accessed March 2021, ePublication
- US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
- International Journal of Toxicology, May 2011, pages 5S-16S
- Skin Research and Technology, November 2007, pages 417-24
- Journal of the American College of Toxicology, September 1985, pages 223-248
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Active
4th on the list, which puts it at an estimated 2–10% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
Soothing
Anti-Aging
Pore Minimizer
15 scientific references
- International Journal of Dermatology, February 2021, pages 166-173
- Biomolecules & Therapeutics, July 2019, pages 562-569
- Experimental Dermatology, February 2019, pages 15-22
- Dermatologic Therapy, September 2017, ePublication
- Journal of Investigative Dermatology, May 2017, page S116
- International Journal of Pharmaceutics, March 2017, pages 158-162
- Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
- Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
- Skin Pharmacology and Physiology, June 2014, pages 311-315
- International Journal of Pharmacy, January 2013, pages 192-201
- Dermatoendrocrinology, July 2012, pages 308-319
- International Journal of Toxicology, September 2005, pages 1-31
- Dermatologic Surgery, July 2005, pages 860-865
- International Journal of Cosmetic Science, October 2004, pages 231-238
- Journal of Cosmetic Dermatology, April 2004, pages 88-93
-
Estimated level
- 2–10%
-
Confidence
- Moderate — INCI order above the 1% line
-
Roles
-
Plant extract, Texture agent
5th on the list, which puts it at an estimated 2–10% of the formula.
Chondrus Crispus Extract is an extract of the carrageenan, Chondrus crispus, Gigartinaceae
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Solvent
6th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Irish Moss
Hydration
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Antioxidant
8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone
Anti-Aging
Hydration
4 scientific references
- Journal of Oleo Science, February 2019, pages 183-191
- Applied Environmental Microbiology, June 2018, ePublication
- Journal of Biosciences, May-June 2004, pages 345-353
- Scientific Reports, April 2021, pages 1–7
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Emollient, Occlusive, Texture agent
9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ceratonia Siliqua Gum is the ground seed of the ripe fruit of St. John's Bread (carob), Ceratonia siliqua L. (Locust bean), Leguminosae
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Agar
Hydration
5 scientific references
- IOP Conference Series Earth and Environmental Science, February 2020
- Marine Drugs, November 2018, pages 1-41
- International Journal of Innovative Research in Science, Engineering and Technology, February 2018, ePublication
- Carbohydrate Polymers, July 2013, Volume 96, Issue 1, pages 71-81
- Biomedical Materials, November 2008, Volume 3, Number 4
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Soothing
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Urea, (2,5-dioxo-4-imidazolidinyl)-
Soothing
8 scientific references
- Chemistry Series, March 2020, pages 7-21
- Molecules, June 2019, pages 1-33
- European Journal of Pharmacology, February 2018, pages 68-78
- Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
- Pharmacognosy Review, Volume 5, July-December 2011
- International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
- Journal of Occupational Medicine and Toxicology, October 2008, ePublication
- https://wwwaccessdatafdagov/scripts/cdrh/cfdocs/cfcfr/CFRSearchcfm?CFRPart=347&showFR=1
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Soothing
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Sucrose
Hydration
8 scientific references
- Supercharged Hydration
- How Hyaluronic Acid Benefits Skin
- What is Dehydrated Skin & How to Choose the Best Products
- What Your Moisturizer Must Contain
- Moisturizer Myths You Should Stop Believing Now
- The Benefits of Glycerin in Skin Care
- The Best Face Oils for Skin
- How Facial Oils Help Skin
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ultramarines (blue, green, pink, red and violet) are synthetic pigments composed of complex sodium aluminum sulfosilicates having a typical formula Na(AlSiO)S with proportions of each element varying with each colour. To identify the colorant allowed for use in the European Union (EU), the INCI Name CI 77007 must be used.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
Hydration
5 scientific references
- PLoS One, October 2016, ePublication
- Contact Dermatitis, May 2016, pages 281-288
- International Journal of Toxicology, September 2013, pages 5S-21S
- Personal Care, 2008, pages 1-4
- Cosmetic Science Technology, 2006, pages 1-11
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
6-Amino-9-beta-D-ribofuranosyl-9H-purine
Soothing
8 scientific references
- PubChem, Accessed May 2021, ePublication
- Cosmetic Ingredient Review, September 2020, pages 1-38
- Experimental Dermatology, August 2014, pages 553-554
- Journal of Investigative Dermatology, August 2011, pages 526-546
- International Journal of Cosmetic Science, December 2006, pages 447-451
- British Journal of Pharmacology, October 2008, issue 4, pages 475-486
- PloS One, May 2008 (ePublication)
- >International Journal of Cosmetic Science, August 2006, pages 447-451
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt
Soothing
Dark Spot Fading
8 scientific references
- How to Care for Red, Sensitive Skin
- 7 Best Products for Sensitive Skin
- Skincare Tips for Calming Redness
- Skin-Soothing Ingredients
- How the Paula’s Choice CALM Collection Works
- The Best Moisturizers for Sensitive Skin
- The Best Ways to Treat Acne and Sensitive Skin
- Skin Care for Extremely Dry, Sensitive Skin
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Texture agent
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Maltodextrin
Oil Control
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Potassium chloride
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2,3-Propanetriol, homopolymer, tetradecanoates (1:1) (10 mol glycerol average molar ratio)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
UV filter
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
UV filter, Texture agent
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Titanium dioxide (CI 77891)
Anti-Aging
10 scientific references
- Journal of Cosmetic Dermatology, February 2021, pages 532-537
- Frontiers in Bioengineering and Biotechnology, June 2020
- Journal of Nanoparticle Research, March 2020
- Journal of the European Academy of Dermatology and Venereology, November 2019, pages 34-46
- Photodermatology, Photoimmunology and Photomedicine, November 2019, pages 442-446
- Journal of Cosmetic Science, September 2019, pages 223-234
- Materials, July 2019, pages 1-24
- Photodermatology, Photoimmunology, and Photomedicine, April 2011, pages 58-67
- Skin Therapy Letter, July-August 2008, pages 5-7
- Environmental and Health Perspectives, July 2008, pages 893
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Calcium Aluminium Borosilicate is a glass consisting essentially of calcium and aluminium borosilicates
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Chelator, pH adjuster
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Trisodium citrate
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Exfoliant, Texture agent
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Calcium Titanium Borosilicate is a glass consisting essentially of calcium and titanium borosiliates
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Fluorphlogopite, Mg3K[AlF2O(SiO3)3] (synthetic)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent, Solvent
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Butanamide, N,2,3-trimethyl-2-(1-methylethyl)-
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
Hydration
Anti-Aging
Soothing
5 scientific references
- Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
- Journal of Cosmetic Dermatology, July 2014, pages 277-287
- Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
- DermatoEndocrinology, July-December 2012, pages 253-258
- Journal of Drugs in Dermatology, September 2011, pages 990-1000
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
2,2,2-Trichloro-1-phenylethyl Acetate; rosacetate; rosacetol; rose crystals
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Exfoliant, Texture agent
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tin dioxide (CI 77861)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Emollient, Occlusive
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Collagens, hydrolyzates. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of hoofs and horns composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin.
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Texture agent, Solvent
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-dihydroxypropane
Hydration
4 scientific references
- PubChem Compound Summary, April 2021, ePublication
- SpecialChem, Accessed April 2021, ePublication
- Cosmetic Ingredient Review, June 2018, pages 1-73
- Cosmetics & Toiletries, May 2013, pages 81-86
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ferric Tetracarboxyphthalocyanine is the organometallic.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid
Anti-Aging
Hydration
5 scientific references
- Journal of Evidence-Based, Complementary and Alternative Medicine, October 2017, pages 816-823
- Journal of Medicinal Food, October 2016, pages 1, 172-1, 179
- Nutrition Journal, July 2013, ePublication
- Journal of Drugs in Dermatology, 2011, issue 9, pages 990-1000
- Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38-43
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Antioxidant, pH adjuster
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ascorbic acid
Anti-Aging
Dark Spot Fading
Evens Skin Tone
12 scientific references
- Drug Delivery, February 2021, pages 445-453
- Journal of Cosmetic Dermatology, December 2020, pages 3, 262-3, 269
- Journal of Oral and Maxillofacial Pathology, May-August 2020, pages 374-382
- Journal of Cosmetic Dermatology, March 2020, pages 671-676
- Journal of Clinical and Aesthetic Dermatology, July 2017 pages 14-17
- Journal of Drugs in Dermatology, July 2016, pages 863-867
- Clinical, Cosmetic, and Investigational Dermatology, September 2015, pages 463-470
- Indian Dermatology Online Journal, April-June 2013, pages 143-146
- AAPS PharmSciTech, July 2011, pages 917-923
- Journal of Drugs in Dermatology, July 2008, Supplement, pages s2-s6
- International Journal of Toxicology, Supplement 2, March 2005, pages 51-111
- Skin Pharmacology and Physiology, July-August 2004, pages 200-206
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (6 mol glycerol average molar ratio)
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Decanoic acid, ester with 1,2,3-propanetriol octanoate;
Glycerides, mixed decanoyl and octanoyl
Hydration
5 scientific references
- International Journal of Toxicology, September 2020, pages 34-35
- Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
- International Journal of Toxicology, January 2003, pages 4-5
- Food and Chemical Toxicology, January 2000, pages 79-98
- Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Surfactant
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lecithins, hydrogenated
Hydration
4 scientific references
- International Journal of Toxicology, September 2020, pages 5S-25S
- Nanocosmetics, June 2019, pages 95–140
- Current Drug Delivery, 2016, pages 111–120
- Pharmaceutical Research, February 2013, pages 538–55
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Adenosine 5'-triphosphate.
Soothing
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Adenosine 5'-(trihydrogen diphosphate), 5'->5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Antioxidant
44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-Benzenediol, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-
Anti-Aging
Dark Spot Fading
Soothing
8 scientific references
- Biomedicine and Pharmacotherapy, November 2021, ePublication
- International Journal of Molecular Sciences, October 2021, pages 1–26
- Phytotherapy Research, March 2020, pages 435–447
- Biomolecules and Therapeutics, October 2018, pages 1–14
- Journal of Cosmetic and Laser Therapy, May 2018 ePublication
- Journal of Drugs in Dermatology, December 2013, pages 1389-1394
- Archives of Biochemistry and Biophysics, April 2011, pages 164-170
- Antioxidants and Redox Signaling, December 2001, pages 1041-1064
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Antioxidant, Peptide, Chelator
45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
SH-Octapeptide-4 is a recombinant human peptide produced synthetically to be identical to the protein, Enkephalin. It contains 8 amino acids consisting of glycine, histidine, leucine, lysine, phenylalanine, and tyrosine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Antioxidant, Peptide, Chelator, pH adjuster
46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Decapeptide-7 is a single chain recombinant human peptide, produced synthetically to be identical to the protein, Enkephalin. It contains 10 amino acids consisting of glycine, leucine, lysine, phenylalanine, serine, threonine and tyrosine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active, Peptide
47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues
Anti-Aging
Hydration
6 scientific references
- Cosmetics, November 2020, Issue 7, Volume 4, page 91
- La Clinica Terapeutica, November 2020, pages e539-e548
- https://wwwcir-safetyorg/sites/default/files/AcetylHexapeptide-8pdf
- Cutaneous and Ocular Toxicology, March 2015, pages 46-52
- European Journal of Pharmaceutical Sciences, February 2015, pages 27-35
- Dermatologic Therapy, September-October 2007, issue 5, pages 343-349
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycine, N-(N-L-.gamma.-glutamyl-L-cysteinyl)-
Anti-Aging
8 scientific references
- Journal of Cosmetic Dermatology, June 2019, pages 728–737
- Clinical Cosmetic and Investigative Dermatology, April 2017, pages 147-153 and October 2014, pages 267-274
- Nutrients, August 2017, pages 1-27
- DermatoEndocrinology, July 2012, pages 308-319
- Journal of Agricultural and Food Chemistry, 2011, pages 3, 940-3, 949
- The Dermatologist, October 2011, volume 19, issue 10
- Journal of Dermatologic Science, May 2010, pages 85-90
- Free Radical Biology and Medicine, October 1994, pages 333-349
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Antioxidant, Peptide, Texture agent, Chelator
49th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Oligopeptide-29 is a synthetic peptide containing 12 amino acids consisting of alanine, arginine, histidine, leucine, lysine, proline and serine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide, Texture agent
50th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Oligopeptide-32 is the synthetic peptide containing 12 amino acids consisting of alanine, arginine, hisitidine, leucine, lysine, propline, serine, and tryptophan
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
51st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lysine, synthetic pentapeptide with serine, and threonine, hexadecanoyl derivatives
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
52nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl-
Anti-Aging
4 scientific references
- International Journal of Toxicology, November 2018, pages 90S-102S
- Cosmetics, May 2017, pages 1-14
- Experimental and Therapeutic Medicine, August 2016, pages 1, 171-1, 176
- International Journal of Cosmetic Science, June 2000, pages 207-218
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Peptide
53rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl Tetrapeptide-5 is product obtained by the acetylation of Tetrapeptide-5
Anti-Aging
Soothing
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
54th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl Tetrapeptide-9 is a reaction product of acetic acid and Tetrapeptide-9
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
55th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl Tetrapeptide-2 is product obtained by the acetylation of Tetrapeptide-2
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Humectant, Active, Peptide
56th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl Octapeptide-3 is the reaction product of acetic acid and Octapeptide-3
Anti-Aging
Hydration
8 scientific references
- 5 Super Anti-Aging Antioxidants Your Skin Needs
- How to Keep Your Neck & Chest Looking Young
- Acne & Aging Skin
- How to Diminish Uneven Skin Tone and Get Your Glow Back
- What Are Peptides and What Do They Do for Skin?
- The Truth About Firming Creams
- Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
- Anti-Aging Superstars
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
57th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl Hexapeptide-1 is reaction product of Alanine, arginine, histidine, leucine, phenylalanine and tryptophane hexapeptide with acetic acid
Anti-Aging
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
58th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Polymer derived from alanine, histidine and lysine, copper derivative, hydrochloride
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
59th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tyrosine acetate and arginine, hexadecyl ester, dipeptide
Anti-Aging
3 scientific references
- Pharmaceuticals, July 2021, pages 1–22
- Journal of Cosmetic Dermatology, June 2020, pages 1, 415–1, 425
- Journal of the European Academy of Dermatology and Venereology, Supplement 1, February 2016, pages 18–20
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
60th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Acetyl sh-Pentapeptide-1 is product obtained by the acetylation of sh-Pentapeptide-1
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
61st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Biotinoyl Tripeptide-1 is the reaction product of Biotin and Tripeptide-1
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
62nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Copper Tripeptide-1 is a copper complex of Tripeptide-1
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
63rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Dipeptide-4 is a synthetic peptide consisting of cysteine and glycine; Cysteine, synthetic dipeptide with glycine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
64th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hexapeptide-9 is a synthetic peptide containing Glutamine, Glycine and Proline residues
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
65th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hexapeptide-11 is a synthetic peptide containing Alanine, Phenylalanine, Proline and Valine residues
Anti-Aging
Hydration
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
66th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hexapeptide-12 is a synthetic peptide containing Alanine, Glycine, Proline and Valine residues
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
67th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Myristoyl Pentapeptide-17 is the product of the reaction of myristic acid and Pentapeptide-17.
Hydration
Soothing
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
68th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Myristoyl Hexapeptide-16 is the product of the reaction of myristic acid and Hexapeptide-16
Hydration
Soothing
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
69th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Myristoyl Pentapeptide-3 is the reaction product of Myristic Acid with a synthetic peptide containing Threonine, Serine and lysine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
70th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Nonapeptide-1 is a synthetic nonapeptide derived from arginine, lysine, methionine, phenylalanine, proline, tryptophan and valine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Antioxidant, Peptide, Chelator
71st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Nicotinoyl Tripeptide-1 is the product obtained by the reaction of Niacin with Tripeptide-1
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
72nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Nonapeptide-7 is a synthetic peptide consisting of alanine, arginine, cysteine, leucine, phenylalanine, proline, serine and threonine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Antioxidant, Peptide
73rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Nicotinoyl Tripeptide-35 is the product obtained by the reaction of Niacin and Tripeptide-35.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
74th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Nicotinoyl Dipeptide-26 is the product obtained by the reaction of Niacin and Dipeptide-26.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
75th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Nicotinoyl Dipeptide-23 is the product obtained by the reaction of Niacin and Dipeptide-23.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
76th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octapeptide-2 is a synthetic peptide composed of glutamic acid, glutamine, leucine, lysine, and threonine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
77th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Palmitoyl Tripeptide-5 is the reaction product of palmitic acid and Tripeptide-5
Anti-Aging
6 scientific references
- Molecules, March 2023, pages 1–12
- Pharmaceuticals, July 2021, pages 1–22
- Frontiers in Chemistry, October 2020, pages 1–8
- Journal of Topical and Cosmetic Science, October 2020, pages 77–82
- Household and Personal Care Today, November/December 2015, pages 6–11
- The Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38–43
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
78th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Glycine, N-(1-oxohexadecyl)-L-valylglycyl-L-valyl-L-alanyl-L-prolyl-
Anti-Aging
6 scientific references
- Frontiers in Chemistry, October 2020, ePublication
- International Journal of Toxicology, 2018, pages 90S-102S
- Cosmetics, Volume 4, Issue 16, May 2017, pages 1–17
- Tissue Engineering and Regenerative Medicine, February 2017, pages 73–80
- Biomolecules and Therapeutics, July 2014, pages 321–327
- International Journal of Cosmetic Science, June 2005, pages 155–160
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
79th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Pentapeptide-13 is a synthetic peptide consisting of alanine, arginine, lysine, proline and valine
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
80th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Palmitoyl Tetrapeptide-10 is the product obtained by the reaction of palmitic acid and Tetrapeptide-10
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
81st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Palmitoyl Tripeptide-38 is the reaction product of palmitic acid and Tripeptide-38
Anti-Aging
1 scientific reference
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
82nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Palmitoyl Tripeptide-29 is the product obtained by the reaction of palmitic acid and Tripeptide-29
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
83rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Palmitoyl Tripeptide-8 is the product obtained by the reaction of palmitic acid and Tripeptide-8
Anti-Aging
8 scientific references
- 5 Super Anti-Aging Antioxidants Your Skin Needs
- How to Keep Your Neck & Chest Looking Young
- Acne & Aging Skin
- How to Diminish Uneven Skin Tone and Get Your Glow Back
- What Are Peptides and What Do They Do for Skin?
- The Truth About Firming Creams
- Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
- Anti-Aging Superstars
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
84th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tripeptide-1 is a synthetic peptide containing glycine, histidine, and lysine
Anti-Aging
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Peptide
85th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tetrapeptide-44 is the synthetic peptide consisting of alanine, glycine, phenylalanine and proline.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Peptide
86th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tetrapeptide-30 is the synthetic peptide consisting of glutamic acid, lysine and proline
Anti-Acne
Dark Spot Fading
Soothing
2 scientific references
- European Journal of Pharmaceutics and Biopharmaceutics, March 2018, pages 28-33
- Cosmetics, May 2017 ePublication
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
87th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tripeptide-10 Citrulline is the reaction product of Citrulline and Tripeptide-10; Aspartic acid, synthetic tripeptide with isoleucine and lysine, reaction product with 5-ureido-2-aminopentanoic acid
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
88th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tripeptide-32 is the synthetic peptide consisting of proline, serine and threonine
Anti-Aging
Hydration
8 scientific references
- 5 Super Anti-Aging Antioxidants Your Skin Needs
- How to Keep Your Neck & Chest Looking Young
- Acne & Aging Skin
- How to Diminish Uneven Skin Tone and Get Your Glow Back
- What Are Peptides and What Do They Do for Skin?
- The Truth About Firming Creams
- Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
- Anti-Aging Superstars
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
89th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tripeptide-29 is the synthetic peptide consisting of glycine, proline and hydroxyproline
Anti-Aging
3 scientific references
- Amino Acids, January 2018, pages 29-38
- Journal of Cosmetic Dermatology, December 2016, pages 514-519
- Journal of the Society of Cosmetic Scientists of Korea, 2010, pages 65-69
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
90th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-22 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Transforming Growth Factor Beta 1. It contains a maximum of 390 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
91st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Epidermal Growth Factor. It contains a maximum of 53 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
92nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-1 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Basic Fibroblast Growth Factor used as such or adapted to the production host. It contains a maximum of 288 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
93rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
It is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Vascular Endothelial Growth Factor A used as such or adapted to the production host.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
94th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
It is a single chain recombinant human peptide,produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Insulin-Like Growth Factor used as such or adapted to the production host.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
95th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
sh-Polypeptide-11 is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Acidic Fibroblast Growth Factor 1 used as such or adapted to the production host. It contains a maximum of 155 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Peptide
96th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
It is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Keratinocyte Growth Factor used as such or adapted to the production host.
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Occlusive, Active, Peptide
97th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
PGF,PLGF
-
Estimated level
- under 1%
-
Confidence
- Moderate — listed below the 1% line
-
Roles
-
Active, Antioxidant, Peptide
98th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hepatocyte Growth Factor