Numbuzin No.5+ Glutathione Vitamin Concentrated Serum

Numbuzin

No.5+ Glutathione Vitamin Concentrated Serum

face serum

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Fit by skin type

General, ingredient-based — not your personalized match.

Dry
57%
Combination (dry)
57%
Balanced
87%
Combination (oily)
83%
Oily
83%

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47
Ingredients
6
Benefits
5
Actives
Find Dupes

Daily serum enriched with tone-evening ingredients, glutathione and vitamin C, and antioxidants, to gently yet effectively fade dark spots and hyperpigmentation, leaving you with glowing, clear skin.

Key Insights

Benefits

6
Anti-Aging
Dark Spot Fading
Evens Skin Tone
Hydration
Pore Minimizer
Soothing

Active Ingredients

5
Ceramides Hyaluronic acid Vitamin B3 (niacinamide) Vitamin B5 (panthenol) Vitamin C

Risks

1
Synthetic polymer

About No.5+ Glutathione Vitamin Concentrated Serum

Overview

No.5+ Glutathione Vitamin Concentrated Serum is a lightweight serum from Numbuzin, a brand based in Korean. The formula is built mainly around hydration, soothing and brightening and tone. The ingredient list runs to 47 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. Hydration is handled by Butylene Glycol, Panthenol and Glycerin, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Butylene Glycol, Panthenol, Glycerin and Ethylhexylglycerin.

Soothing: High. Ingredients aimed at visible redness and reactivity, and here that comes from Panthenol, Bisabolol, Allantoin and Beta-glucan.

Brightening: High. Ingredients that act on uneven tone and post-inflammatory marks, and here that comes from Niacinamide, Tranexamic Acid, 3-o-ethyl Ascorbic Acid and Alpha-arbutin.

Barrier support: High. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Panthenol, Butyrospermum Parkii Butter and Hydrogenated Lecithin.

Who it suits

On richness alone it suits Balanced, Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on cell renewal and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, silicone-free and microplastic-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • Silicone-free
  • No microplastics
  • Strong humectant content for hydration
  • Meaningful barrier-support lipids
  • Several soothing ingredients
  • No common irritants flagged in the list

Things to know

  • 2 ingredients could feed malassezia (fungal acne)
  • Contains ingredients usually flagged for review during pregnancy

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin
  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Anti-Aging 20 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Hydration 16 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Soothing 14 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Dark Spot Fading 6 ingredients

    Fades hyperpigmentation and evens out dark spots over time

  • Evens Skin Tone 6 ingredients

    Brightens and balances complexion for a more uniform appearance

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

Does not target

Anti-Acne Blackhead Reducing Oil Control Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

2nd on the list, which puts it at an estimated 5–20% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
Niacinamide Vitamin B3 (niacinamide)

3rd on the list, which puts it at an estimated 5–20% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
Panthenol Vitamin B5 (panthenol)

4th on the list, which puts it at an estimated 2–10% of the formula.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing

5th on the list, which puts it at an estimated 2–10% of the formula.

Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-

Dark Spot Fading Evens Skin Tone Anti-Aging

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

D-Glucitol

Hydration

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Vaccinium Vitis-Idaea Fruit Extract is an extract of the fruit of the Cowberry, Vaccinium vitis-idaea L., Ericaceae

Anti-Aging Soothing

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Docosan-1-ol

Hydration

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Dihydroxypentane

Hydration

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butyrospermum Parkii Butter is the fat obtained from the fruit of the Shea Tree, Butyrospernum parkii, Sapotaceae

Anti-Aging Hydration Soothing

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration High

Ingredients that pull and hold water in the upper layers of skin

Barrier support High

Lipids and repair signals that support skin barrier integrity

Antioxidant support Low

Ingredients that mop up free radicals from UV and pollution

Oil control Moderate

Ingredients that moderate sebum or absorb shine

Brightening High

Ingredients that act on uneven tone and post-inflammatory marks

Soothing High

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling None

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (7)

Supporting ingredients (40)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Butylene Glycol Tranexamic Acid 1,2-hexanediol Neopentyl Glycol Dicaprate Caprylic/capric Triglyceride Sorbitol Vaccinium Vitis-idaea Fruit Extract Behenyl Alcohol Pentylene Glycol Glycerin Chondrus Crispus Extract Butyrospermum Parkii Butter Saccharum Officinarum Extract Carbomer Alpha-arbutin Bisabolol Tromethamine Ethylhexylglycerin Bifida Ferment Lysate Adenosine Hydrogenated Lecithin Allantoin Xanthan Gum Glutathione Disodium Edta Melia Azadirachta Flower Extract Ocimum Sanctum Leaf Extract Melia Azadirachta Leaf Extract Curcuma Longa Root Extract Corallina Officinalis Extract Beta-glucan Dipotassium Glycyrrhizate Tocopherol Tocopheryl Acetate Hydroxypropyl Cyclodextrin Ubiquinone Thioctic Acid Tremella Fuciformis Extract Potassium Hydroxide

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Silicone-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • Oil-free
  • No animal-derived ingredients

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Vitamin C (L-ascorbic acid)
  • PHAs (gluconolactone)
  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • Benzoyl peroxide

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Retinoids (retinol, retinal)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • AHAs (glycolic, lactic)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • BHA (salicylic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Treat" step.

  • Apply to clean, dry skin and give it a minute to absorb before the next layer.
  • Introduce one new treatment at a time so you can identify what is working.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Contains Alpha-arbutin, usually reviewed with a doctor during pregnancy.
Fungal acne (malassezia)
2 ingredients could feed malassezia: Butyrospermum Parkii Butter, Bifida Ferment Lysate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 47 ingredients on the label.

9
Plant extract

Botanical material, usually for antioxidants or scent

8
Antioxidant

Neutralises free radicals from UV and pollution

8
Texture agent

Sets the thickness, spread and stability of the formula

7
Active

Changes how skin behaves rather than how it feels

7
Humectant

Draws water into the upper layers of skin

5
Solvent

Dissolves and carries everything else

3
pH adjuster

Sets the acidity the formula needs to work

2
Soothing

Calms visible redness and irritation

2
Emollient

Softens and smooths by filling gaps between skin cells

2
Occlusive

Forms a film that slows water loss

2
Surfactant

Lifts oil and dirt, or holds oil and water together

1
Chelator

Binds trace metals that would otherwise spoil the formula

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Butylene Glycol Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
3 Niacinamide Active
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

3rd on the list, which puts it at an estimated 5–20% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
4 Panthenol Active
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

4th on the list, which puts it at an estimated 2–10% of the formula.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line

5th on the list, which puts it at an estimated 2–10% of the formula.

Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-

Dark Spot Fading Evens Skin Tone Anti-Aging
8 scientific references
  • Journal of Cosmetic Dermatology, February 2021, pages 561-565
  • International Journal of Medical Sciences, March 2020, pages 903-911
  • Journal of Cosmetic Dermatology, April 2019, pages 563-567
  • Journal of Cutaneous and Aesthetic Surgery, January-March 2019, pages 63-67; and July-August 2013, pages 139-143
  • BioMed Research International, November 2018, ePublication
  • Dermatologic Surgery, June 2018, pages 814-825
  • Dermatology and Therapy, September 2017, pages 417-424
  • Journal of Research in Medical Sciences, August 2014, pages 753-757
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

6th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,2-Dimethyl-1,3-propanediyl didecanoate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl

Hydration
5 scientific references
  • International Journal of Toxicology, September 2020, pages 34-35
  • Periodica Polytechnica Chemical Engineering, 2014, pages 43-48
  • International Journal of Toxicology, January 2003, pages 4-5
  • Food and Chemical Toxicology, January 2000, pages 79-98
  • Journal of the Society of Cosmetic Chemists, August 1985, pages 303-311
9 Sorbitol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

D-Glucitol

Hydration
7 scientific references
  • International Journal of Pharmaceutics, January 2019, pages 175–183
  • Clinical Medicine and Research, January 2017, pages 75–87
  • Frontiers in Microbiology, December 2017, ePublication
  • 3 Biotech, June 2012, pages 115-125
  • The Journal of Clinical and Aesthetic Dermatology, August 2011, pages 31-49
  • Applied Biochemistry and Biotechnology, July-September 2004, pages 321-336
  • https://wwwcir-safetyorg/sites/default/files/Mannitol, %20Sorbitol, %20Xylitol_0pdf
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant, Plant extract

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Vaccinium Vitis-Idaea Fruit Extract is an extract of the fruit of the Cowberry, Vaccinium vitis-idaea L., Ericaceae

Anti-Aging Soothing
3 scientific references
  • Molecules, January 2019, ePublication; and December 2017, ePublication
  • Plant Foods for Human Nutrition, November 2017, pages 360-364
  • International Journal of Molecular Sciences, October 2015, pages 25, 673-24, 706
11 Behenyl Alcohol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Texture agent

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Docosan-1-ol

Hydration
5 scientific references
  • International Journal of Cosmetic Science, April 2017, pages 206-216
  • International Journal of Toxicology, May 2014, pages 77-142
  • Expert Opinion on Pharmacotherapy, March 2010, Volume 11, pages 853-860
  • Journal of the American College of Toxicology, 1988, pages 1-55
  • CosmeticsInfoorg, ePublication
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Dihydroxypentane

Hydration
4 scientific references
  • https://thedermreviewcom/pentylene-glycol/
  • Regulatory Toxicology and Pharmacology, July 2017, pages 106-111
  • Prospector, June 2015, ePublication
  • International Journal of Toxicology, October 2012, pages 147S-168S
13 Glycerin Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract, Texture agent

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Chondrus Crispus Extract is an extract of the carrageenan, Chondrus crispus, Gigartinaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butyrospermum Parkii Butter is the fat obtained from the fruit of the Shea Tree, Butyrospernum parkii, Sapotaceae

Anti-Aging Hydration Soothing
3 scientific references
  • Journal of Clinical and Aesthetic Dermatology, June 2011, pages 45-55
  • Journal of Agricultural and Food Chemistry, October 2003, pages 6, 268-6, 273
  • Journal of Allergy and Clinical Immunology, February 2009, page S41
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3-O-Ethyl Ascorbic Acid is the organic compound.

Anti-Aging Evens Skin Tone Dark Spot Fading
5 scientific references
  • Free Radical Biology and Medicine, September 2021, pages 151–169
  • Life, May 2021, pages 1–13
  • International Journal of Pharmaceutics, December 2019, pages 1–9
  • Journal of Cosmetic Science, July-August 2018, pages 233–243
  • AAPS PharmSciTech, June 2016, pages 767–777
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Plant extract

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Saccharum Officinarum Extract is an extract of the sugar cane, Saccharum officinarum L., Poaceae

18 Carbomer Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether

Synthetic polymer
19 Alpha-arbutin Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

4-Hydroxyphenyl-alpha-D-glucopyranoside

Anti-Aging Dark Spot Fading Evens Skin Tone
20 Bisabolol Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

(R*,R*)-.alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (theta,theta)-(+/-)-; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (S-(theta,theta))- (levomenol)

Soothing Anti-Aging
6 scientific references
  • CosmeticsInfoorg, Accessed May 2021, ePublication
  • International Journal of Cosmetic Science, August 2019, pages 299-303
  • International Journal of Toxicology, September 2017, pages 24S-25S
  • Cutis, November 2015, pages 337-342
  • Current Pharmaceutical Biotechnology, 2014, pages 173-181
  • Food and Chemical Toxicology, October 2011, pages 2580-2585
21 Tromethamine pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Bifida Ferment Lysate is a lysate of the product obtained by the fermentation of Bifida

Hydration Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, hydrogenated

Hydration
4 scientific references
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Nanocosmetics, June 2019, pages 95–140
  • Current Drug Delivery, 2016, pages 111–120
  • Pharmaceutical Research, February 2013, pages 538–55
26 Allantoin Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Soothing

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urea, (2,5-dioxo-4-imidazolidinyl)-

Soothing
8 scientific references
  • Chemistry Series, March 2020, pages 7-21
  • Molecules, June 2019, pages 1-33
  • European Journal of Pharmacology, February 2018, pages 68-78
  • Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
  • Pharmacognosy Review, Volume 5, July-December 2011
  • International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
  • Journal of Occupational Medicine and Toxicology, October 2008, ePublication
  • https://wwwaccessdatafdagov/scripts/cdrh/cfdocs/cfcfr/CFRSearchcfm?CFRPart=347&showFR=1
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
28 Xanthan Gum Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant, Texture agent

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Xanthan gum

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycine, N-(N-L-.gamma.-glutamyl-L-cysteinyl)-

Anti-Aging
8 scientific references
  • Journal of Cosmetic Dermatology, June 2019, pages 728–737
  • Clinical Cosmetic and Investigative Dermatology, April 2017, pages 147-153 and October 2014, pages 267-274
  • Nutrients, August 2017, pages 1-27
  • DermatoEndocrinology, July 2012, pages 308-319
  • Journal of Agricultural and Food Chemistry, 2011, pages 3, 940-3, 949
  • The Dermatologist, October 2011, volume 19, issue 10
  • Journal of Dermatologic Science, May 2010, pages 85-90
  • Free Radical Biology and Medicine, October 1994, pages 333-349
30 Disodium Edta Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Chelator

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Disodium dihydrogen ethylenediaminetetraacetate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Melia Azadirachta Flower Extract is an extract of the flowers of the Neem Tree, Melia Azadirachta L., Meliaceae

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ocimum Sanctum Leaf Extract is an extract of the leaves of Ocimum sanctum, Labiatae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Melia Azadirachta Leaf Extract is an extract of the leaves of the Neem Tree, Melia azadirachta L., Meliaceae

Anti-Aging
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
34 Ceramide NP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Hydration Anti-Aging
11 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Curcuma Longa Root Extract is an extract of the rhizomes of the Turmeric, Curcuma longa L., Zingiberaceae

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Corallina Officinalis Extract is an extract of the Alga, Corallina officinalis L., Corallinaceae

Hydration Anti-Aging
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

beta-Glucan is a polysaccharide consisting of b(1-3) linked glucose chains carrying b(1-6) linked glucose sidechains

Soothing Hydration
6 scientific references
  • Journal of Cosmetic Dermatology, December 2018, pages 1, 101-1, 107
  • International Journal of Molecular Sciences, September 2017, pages 1-48
  • Phytotherapy Research, February 2014, pages 159-166
  • Cosmetic Ingredient Review, October 2012, pages 1-52
  • Journal of Drugs in Dermatology, February 2007, pages 167-170
  • International Journal of Cosmetic Science, October 2005, page 292
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

.alpha.-d-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-d-glucopyranuronosyl-, dipotassium salt

Soothing Dark Spot Fading
8 scientific references
  • How to Care for Red, Sensitive Skin
  • 7 Best Products for Sensitive Skin
  • Skincare Tips for Calming Redness
  • Skin-Soothing Ingredients
  • How the Paula’s Choice CALM Collection Works
  • The Best Moisturizers for Sensitive Skin
  • The Best Ways to Treat Acne and Sensitive Skin
  • Skin Care for Extremely Dry, Sensitive Skin
39 Tocopherol Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E

Anti-Aging Evens Skin Tone Soothing
4 scientific references
  • Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
  • Journal of Investigative Dermatology, November 2001, pages 1212-1217
  • Canadian Family Physician, July 2006, pages 855-856
  • Dermatologic Surgery, April 1999, pages 311-315
40 Ascorbic Acid Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Antioxidant, pH adjuster

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ascorbic acid

Anti-Aging Dark Spot Fading Evens Skin Tone
12 scientific references
  • Drug Delivery, February 2021, pages 445-453
  • Journal of Cosmetic Dermatology, December 2020, pages 3, 262-3, 269
  • Journal of Oral and Maxillofacial Pathology, May-August 2020, pages 374-382
  • Journal of Cosmetic Dermatology, March 2020, pages 671-676
  • Journal of Clinical and Aesthetic Dermatology, July 2017 pages 14-17
  • Journal of Drugs in Dermatology, July 2016, pages 863-867
  • Clinical, Cosmetic, and Investigational Dermatology, September 2015, pages 463-470
  • Indian Dermatology Online Journal, April-June 2013, pages 143-146
  • AAPS PharmSciTech, July 2011, pages 917-923
  • Journal of Drugs in Dermatology, July 2008, Supplement, pages s2-s6
  • International Journal of Toxicology, Supplement 2, March 2005, pages 51-111
  • Skin Pharmacology and Physiology, July-August 2004, pages 200-206
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Antioxidant

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-O-alpha-D-Glucopyranosyl-L-ascorbic acid

Anti-Aging Dark Spot Fading Evens Skin Tone
11 scientific references
  • Journal of the American Academy of Dermatology, December 2020 Supplement, page AB192
  • Nanomaterials, August 2020, pages 1-13
  • Journal of Oral and Maxillofacial Pathology, May-August 2020, pages 374-382
  • Genes, February 2020, ePublication
  • Cosmetics, October 2019, ePublication
  • International Journal of Cosmetic Science, August 2019, pages 378-386
  • International Journal of Pharmaceutics, May 2019, pages 21-29
  • Asian Journal of Beauty and Cosmetology, December 2018, pages 599-607
  • Nutrients, August 2017, pages 1-27
  • Journal of Cutaneous and Aesthetic Surgery, January-March 2013, pages 4-11
  • Skin Research and Technology, May 2006, pages 105-113
42 Tocopheryl Acetate Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate

Anti-Aging Soothing
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

.beta.-Cyclodextrin, 2-hydroxypropyl ethers

44 Ubiquinone Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2,5-Cyclohexadiene-1,4-dione, 2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-, (all-E)-

Anti-Aging Soothing
6 scientific references
  • Free Radical Biology and Medicine, March 2021, pages 282-288
  • Biofactors, November-December 2015, pages 383-390; 2008, pages 245-255; and 2005, pages 179-185
  • Journal of Cosmetic Dermatology, March 2006, issue 1, pages 30-38
  • Journal of Investigative Dermatology, 2005, issue 4, pages 12-13
  • Journal of Dermatological Science, August 2001, Supplement, pages 1-4
  • https://wwwcir-safetyorg/sites/default/files/Ubiquinonepdf
45 Thioctic Acid Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Dithiolane-3-pentanoic acid, (+/-)-

Anti-Aging
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Plant extract

46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Tremella Fuciformis (Mushroom) Extract is an extract of the Mushroom, Tremella Fuciformis

47 Potassium Hydroxide pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Potassium hydroxide

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Frequently asked questions

What ingredients are in No.5+ Glutathione Vitamin Concentrated Serum?

WATER, BUTYLENE GLYCOL, NIACINAMIDE, PANTHENOL, TRANEXAMIC ACID, 1,2-HEXANEDIOL, NEOPENTYL GLYCOL DICAPRATE, CAPRYLIC/CAPRIC TRIGLYCERIDE, SORBITOL, VACCINIUM VITIS-IDAEA FRUIT EXTRACT, BEHENYL ALCOHOL, PENTYLENE GLYCOL, GLYCERIN, CHONDRUS CRISPUS EXTRACT, BUTYROSPERMUM PARKII BUTTER, 3-O-ETHYL ASCORBIC ACID, SACCHARUM OFFICINARUM EXTRACT, CARBOMER, ALPHA-ARBUTIN, BISABOLOL, TROMETHAMINE, ETHYLHEXYLGLYCERIN, BIFIDA FERMENT LYSATE, ADENOSINE, HYDROGENATED LECITHIN, ALLANTOIN, SODIUM HYALURONATE, XANTHAN GUM, GLUTATHIONE, DISODIUM EDTA, MELIA AZADIRACHTA FLOWER EXTRACT, OCIMUM SANCTUM LEAF EXTRACT, MELIA AZADIRACHTA LEAF EXTRACT, CERAMIDE NP, CURCUMA LONGA ROOT EXTRACT, CORALLINA OFFICINALIS EXTRACT, BETA-GLUCAN, DIPOTASSIUM GLYCYRRHIZATE, TOCOPHEROL, ASCORBIC ACID, ASCORBYL GLUCOSIDE, TOCOPHERYL ACETATE, HYDROXYPROPYL CYCLODEXTRIN, UBIQUINONE, THIOCTIC ACID, TREMELLA FUCIFORMIS EXTRACT, POTASSIUM HYDROXIDE.

What are the active ingredients in No.5+ Glutathione Vitamin Concentrated Serum?

NIACINAMIDE, PANTHENOL, 3-O-ETHYL ASCORBIC ACID, SODIUM HYALURONATE, CERAMIDE NP, ASCORBIC ACID, ASCORBYL GLUCOSIDE.

How do I use No.5+ Glutathione Vitamin Concentrated Serum?

Apply it after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.

What skin types is No.5+ Glutathione Vitamin Concentrated Serum good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced, Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is No.5+ Glutathione Vitamin Concentrated Serum good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is No.5+ Glutathione Vitamin Concentrated Serum fungal acne safe?

2 ingredients could feed malassezia: Butyrospermum Parkii Butter, Bifida Ferment Lysate. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use No.5+ Glutathione Vitamin Concentrated Serum while pregnant?

It contains Alpha-arbutin, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.

Is No.5+ Glutathione Vitamin Concentrated Serum fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does No.5+ Glutathione Vitamin Concentrated Serum contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is No.5+ Glutathione Vitamin Concentrated Serum silicone free?

Yes. Reading the full ingredient list, this formula is silicone-free.

Does No.5+ Glutathione Vitamin Concentrated Serum contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is No.5+ Glutathione Vitamin Concentrated Serum paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with No.5+ Glutathione Vitamin Concentrated Serum?

It layers well with Vitamin C (L-ascorbic acid), PHAs (gluconolactone), Azelaic acid, Copper peptides, Bakuchiol, Niacinamide. Take more care combining it with Benzoyl peroxide, Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid) — use them in separate routines or on alternate days.

When should I apply No.5+ Glutathione Vitamin Concentrated Serum?

Use it morning and evening, after toner, before moisturiser.

How many ingredients does No.5+ Glutathione Vitamin Concentrated Serum have?

It lists 47 ingredients, of which 7 are recorded as actives.

Who makes No.5+ Glutathione Vitamin Concentrated Serum?

Numbuzin, a brand based in Korean.

Brand
Numbuzin
Country
Korean

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