1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
Dr.Althea
345 Relief Serum
face serum
Dr.Althea
face serum
Added Last edited
Fit by skin type
General, ingredient-based — not your personalized match.
See how this fits your skin
Take the skin test and I'll show you how suitable this product is for you.
Take the skin testDiscover the Dr.Althea 345 Relief Serum, a lightweight hydrating serum that helps soothe stressed, dehydrated skin while leaving it soft and refreshed. Made to slot right into the beloved 345 routine, the serum layers beautifully before the viral 345 Relief Cream for an extra boost of calming hydration.
345 Relief Serum is a watery-light serum from Dr.Althea. The formula is built mainly around hydration. The ingredient list runs to 50 ingredients, each broken down in full below.
By its ingredient list the formula reads as very light — essentially a water-and-humectant base with little emollient weight. With almost no emollient load it should absorb quickly and finish close to matte. Hydration is handled by Propanediol, Butylene Glycol and Glycerin, humectants that pull water into the upper layers of skin rather than sealing it there.
Hydration: High. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Propanediol, Butylene Glycol, Glycerin and Panthenol.
Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Panthenol, Madecassoside, Asiaticoside and Beta-glucan.
Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Panthenol, Hydrogenated Lecithin and Madecassoside.
On richness alone it suits Combination (oily) and Oily skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.
The formula contributes little or nothing on cell renewal and firmness signalling. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.
Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, silicone-free and microplastic-free. Those claims come from the ingredient list itself, not from the packaging.
It can be used morning and evening. In a routine it goes after toner, before moisturiser. Apply to clean, dry skin and give it a minute to absorb before the next layer. Introduce one new treatment at a time so you can identify what is working.
This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.
Drawn purely from the ingredient list
Scored on how rich or light the formula reads from its INCI order.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Based on the curated benefits documented for this product's ingredients.
Attracts and locks in moisture to keep skin plump and dewy
Boosts collagen and cell turnover to reduce fine lines and wrinkles
Calms redness, irritation, and inflammation for sensitive skin
Fades hyperpigmentation and evens out dark spots over time
Tightens and refines the look of enlarged pores
None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.
The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
3rd on the list, which puts it at an estimated 5–20% of the formula.
1,3-dihydroxypropane
6th on the list, which puts it at an estimated 2–10% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
7th on the list, which puts it at an estimated 1–5% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
8th on the list, which puts it at an estimated 1–5% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
9th on the list, which puts it at an estimated 1–5% of the formula.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1-Decene, homopolymer, hydrogenated
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octanoic acid, monoester with glycerol
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Dihydroxypentane
Each axis is scored from the ingredients present and how high up the list they sit.
Ingredients that pull and hold water in the upper layers of skin
Lipids and repair signals that support skin barrier integrity
Ingredients that mop up free radicals from UV and pollution
Ingredients that moderate sebum or absorb shine
Ingredients that act on uneven tone and post-inflammatory marks
Ingredients aimed at visible redness and reactivity
Retinoids, acids and enzymes that speed surface turnover
Peptides and growth factors that signal for collagen support
"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.
Solvents, emollients, texture agents and preservatives — the formula that carries the actives.
Read from the full ingredient list. A brand's own claim may differ.
Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.
Nothing in this formula belongs to a group our rules can put in conflict, so it layers freely. Order still matters — thinnest texture first.
This product is the "Treat" step.
Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.
Most ingredients do more than one job, so these counts add up to more than the 50 ingredients on the label.
Sets the thickness, spread and stability of the formula
Lifts oil and dirt, or holds oil and water together
Changes how skin behaves rather than how it feels
Dissolves and carries everything else
Draws water into the upper layers of skin
Neutralises free radicals from UV and pollution
Softens and smooths by filling gaps between skin cells
Botanical material, usually for antioxidants or scent
Forms a film that slows water loss
Binds trace metals that would otherwise spoil the formula
Calms visible redness and irritation
Sets the acidity the formula needs to work
Keeps the product free of microbial growth
Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.
1st on the list, which puts it at an estimated 30–80% of the formula.
Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water
2nd on the list, which puts it at an estimated 5–20% of the formula.
Betula Platyphylla Japonica Juice is the sap from the tree, Betula platyphylla japonica, Betulaceae
3rd on the list, which puts it at an estimated 5–20% of the formula.
1,3-dihydroxypropane
4th on the list, which puts it at an estimated 2–10% of the formula.
Melaleuca Alternifolia Leaf Water is an aqueous solution of the steam distillates obtained from the leaves of the Tea Tree, Melaleuca alternifolia, Myrtaceae
5th on the list, which puts it at an estimated 2–10% of the formula.
1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol
6th on the list, which puts it at an estimated 2–10% of the formula.
Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)
7th on the list, which puts it at an estimated 1–5% of the formula.
Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane
8th on the list, which puts it at an estimated 1–5% of the formula.
Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**
9th on the list, which puts it at an estimated 1–5% of the formula.
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol
10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Decanoic acid, ester with 1,2,3-propanetriol octanoate; Glycerides, mixed decanoyl and octanoyl
12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1-Decene, homopolymer, hydrogenated
13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
C14-22 Alcohols is a mixture of synthetic fatty alcohols with 14 to 22 carbons in the alkyl chain
14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone
15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol
16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
C12-20 Alkyl Glucoside is the product obtained by the condensation of C12-20 alcohols with glucose
17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octanoic acid, monoester with glycerol
19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Propanediol, 3-(2-ethylhexyloxy)
20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Xanthan gum
21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,2-Dihydroxypentane
22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Disodium dihydrogen ethylenediaminetetraacetate
23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Octane-1,2-diol
24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Camellia Sinensis Leaf Water is an aqueous solution of the odoriferous principles of the leaves of the Tea, Camellia sinensis, Theaceae
25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hydrolyzed Hyaluronic Acid is the hydrolysate of Hyaluronic Acid derived by acid, enzyme or other method of hydrolysis
26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid
27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium, salt
28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Oxirane, methyl-, polymer with oxirane (98;67)
29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Hyaluronic acid, sodium salt, polymer with 1,1'-sulfonylbis[ethene]
30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lecithins, hydrogenated
31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
O-6-Deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oate
32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Propanoic acid, 3-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino-, (R)-
33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Polymer of glutamic acid
34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
D-Glucoside, Decyl
35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester (2alpha, 3beta, 4alpha)-
36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
beta-Glucan is a polysaccharide consisting of b(1-3) linked glucose chains carrying b(1-6) linked glucose sidechains
37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
(2.alpha.,3.beta.,4.alpha.)-2,3,23-Trihydroxyurs-12-en-28-oic acid
38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-
39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Myo-Inositol, hexakis(dihydrogen phosphate), sodium salt
40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Deoxyribonucleic acid, sodium salts
41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine
42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Aluminum magnesium hydroxide and stearic acid
43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Centella Asiatica Extract is the extract of the whole plant Hydrocotyl, Centella asiatica L., Apiaceae
44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Cholest-5-en-3-ol (beta)-
45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lecithins, hydrolyzed
46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Lecithins, egg yolk
47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
D-Xylose
48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
.beta.-Cyclodextrin, 2-hydroxypropyl ethers
49th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
Tannins. Gallic acid derivatives found in nutgalls, bark and other plant parts, especially oak bark
50th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.
1,3-Benzenediol, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-
Products in the same category that share this formula's distinguishing ingredients.
Arencia
Shares 15 key ingredients with 345 Relief Serum: Water, Glycerin, Butylene Glycol, Propanediol, Niacinamide
Arencia
Shares 14 key ingredients with 345 Relief Serum: Water, Propanediol, Glycerin, Sodium Hyaluronate, Niacinamide
Arencia
Shares 14 key ingredients with 345 Relief Serum: Water, Butylene Glycol, Glycerin, Propanediol, Niacinamide
NEOGEN
Shares 13 key ingredients with 345 Relief Serum: Water, Caprylic/capric Triglyceride, Propanediol, Niacinamide, Glycerin
Arencia
Shares 13 key ingredients with 345 Relief Serum: Water, Butylene Glycol, Propanediol, Glycerin, Niacinamide
SKIN1004
Shares 13 key ingredients with 345 Relief Serum: Water, Butylene Glycol, Niacinamide, Glycerin, Sodium Hyaluronate
WATER, BETULA PLATYPHYLLA JAPONICA JUICE, PROPANEDIOL, MELALEUCA ALTERNIFOLIA LEAF WATER, DIPROPYLENE GLYCOL, BUTYLENE GLYCOL, GLYCERIN, NIACINAMIDE, PANTHENOL, 1,2-HEXANEDIOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, HYDROGENATED POLYDECENE, C14-22 ALCOHOLS, HYDROXYACETOPHENONE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, C12-20 ALKYL GLUCOSIDE, TROMETHAMINE, GLYCERYL CAPRYLATE, ETHYLHEXYLGLYCERIN, XANTHAN GUM, PENTYLENE GLYCOL, DISODIUM EDTA, CAPRYLYL GLYCOL, CAMELLIA SINENSIS LEAF WATER, HYDROLYZED HYALURONIC ACID, HYALURONIC ACID, SODIUM HYALURONATE, POLOXAMER 407, SODIUM HYALURONATE CROSSPOLYMER, HYDROGENATED LECITHIN, MADECASSOSIDE, PANTOTHENIC ACID, POLYGLUTAMIC ACID, DECYL GLUCOSIDE, ASIATICOSIDE, BETA-GLUCAN, ASIATIC ACID, MADECASSIC ACID, SODIUM PHYTATE, SODIUM DNA, CERAMIDE NP, ALUMINUM/MAGNESIUM HYDROXIDE STEARATE, CENTELLA ASIATICA EXTRACT, CHOLESTEROL, LYSOLECITHIN, PHOSPHATIDYLCHOLINE, XYLOSE, HYDROXYPROPYL CYCLODEXTRIN, TANNIC ACID, RESVERATROL.
NIACINAMIDE, PANTHENOL, HYDROLYZED HYALURONIC ACID, HYALURONIC ACID, SODIUM HYALURONATE, SODIUM HYALURONATE CROSSPOLYMER, PANTOTHENIC ACID, CERAMIDE NP.
Layer the serum before 345 Relief Cream to pair lightweight hydration with a comforting moisturizer.
Judged on how rich the formula reads from its ingredient list, it suits Combination (oily), Oily skin best. It is the least natural fit for Dry, Combination (dry) skin.
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
2 ingredients could feed malassezia: Glyceryl Caprylate, Aluminum/magnesium Hydroxide Stearate. That describes the yeast's food supply, not a prediction that they will cause a breakout.
Nothing in this formula is on the standard pregnancy-caution list. That is not medical clearance — check anything you use daily with your doctor or midwife.
Yes. Reading the full ingredient list, this formula is fragrance-free.
No. Reading the full ingredient list, this formula is no drying alcohol.
Yes. Reading the full ingredient list, this formula is silicone-free.
No. Reading the full ingredient list, this formula is essential-oil-free.
Yes. Reading the full ingredient list, this formula is paraben-free.
It layers well with Vitamin C (L-ascorbic acid), Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide.
Use it morning and evening, after toner, before moisturiser.
It lists 50 ingredients, of which 8 are recorded as actives.
Dr.Althea.
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