Aestura Regederm 365 Retinoid Eye Serum

Aestura

Regederm 365 Retinoid Eye Serum

eyes serum

Added Last edited

Fit by skin type

General, ingredient-based — not your personalized match.

Dry
65%
Combination (dry)
65%
Balanced
95%
Combination (oily)
75%
Oily
75%

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55
Ingredients
8
Benefits
7
Actives
Find Dupes

The AESTURA Regederm 365 Retinoid Eye Serum is a targeted anti-aging treatment designed to smooth fine lines, improve firmness, and brighten the delicate eye area. Formulated with a gentle yet effective retinoid complex, this lightweight serum promotes skin renewal while minimizing irritation. Enriched with peptides and barrier-supporting ingredients, it helps restore elasticity and resilience to thin, tired-looking skin around the eyes.

Key Insights

Benefits

8
Anti-Acne
Anti-Aging
Dark Spot Fading
Evens Skin Tone
Hydration
Oil Control
Pore Minimizer
Soothing

Active Ingredients

7
AHA Hyaluronic acid Neuropeptides Retinoids Vitamin B3 (niacinamide) Vitamin B5 (panthenol) Vitamin C

Risks

2
Silicone
Synthetic polymer

About Regederm 365 Retinoid Eye Serum

Overview

Regederm 365 Retinoid Eye Serum is a cushioning serum from Aestura, a brand based in Korea. The formula is built mainly around hydration. The ingredient list runs to 55 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as moderately cushioned — emollient enough to feel like a cream, without the heaviest occlusives near the top. It contains both silicones and oils, a combination that usually finishes smooth and slightly satin and sits well under makeup. Hydration is handled by Butylene Glycol, Glycerin and Betaine, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: Very high. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Butylene Glycol, Glycerin, Betaine and Panthenol.

Soothing: Moderate. Ingredients aimed at visible redness and reactivity, and here that comes from Panthenol, Hydroxypinacolone Retinoate, Niacinamide and Sodium Hyaluronate.

Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Panthenol, Hydrogenated Lecithin and Cholesterol.

Oil control: Moderate. Ingredients that moderate sebum or absorb shine, and here that comes from Niacinamide, Silica and Sodium Polyacrylate.

Who it suits

On richness alone it suits Balanced skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on antioxidant protection. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, essential-oil-free, no drying alcohol, paraben-free, microplastic-free and sulfate-free. Those claims come from the ingredient list itself, not from the packaging.

Where it fits in a routine

It can be used morning and evening. In a routine it goes before moisturiser. Tap along the orbital bone with your ring finger; product migrates upward on its own.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No essential oils
  • No drying alcohol
  • No microplastics
  • Strong humectant content for hydration
  • No common irritants flagged in the list

Things to know

  • 8 ingredients could feed malassezia (fungal acne)
  • Contains ingredients usually flagged for review during pregnancy

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin

May suit

  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 22 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 9 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 6 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Evens Skin Tone 2 ingredients

    Brightens and balances complexion for a more uniform appearance

  • Oil Control 2 ingredients

    Regulates sebum production to reduce shine and greasiness

  • Anti-Acne 1 ingredient

    Targets breakouts by reducing bacteria and unclogging pores

  • Dark Spot Fading 1 ingredient

    Fades hyperpigmentation and evens out dark spots over time

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

Does not target

Blackhead Reducing Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

2nd on the list, which puts it at an estimated 5–20% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration

3rd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging

4th on the list, which puts it at an estimated 2–10% of the formula.

Dimethicone

Hydration
Niacinamide Vitamin B3 (niacinamide)

5th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

6th on the list, which puts it at an estimated 2–10% of the formula.

2-Ethylhexyl stearate

Hydration

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Alcohols, C16-18

Hydration

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt

Hydration
Panthenol Vitamin B5 (panthenol)

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
Sodium Hyaluronate Hyaluronic acid

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Stearic acid, monoester with glycerol

Hydration

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Poly[oxy(dimethylsilylane)], .alpha.-hydro-.omega.-hydroxy-

Hydration

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration Very high

Ingredients that pull and hold water in the upper layers of skin

Barrier support Moderate

Lipids and repair signals that support skin barrier integrity

Antioxidant support None

Ingredients that mop up free radicals from UV and pollution

Oil control Moderate

Ingredients that moderate sebum or absorb shine

Brightening Moderate

Ingredients that act on uneven tone and post-inflammatory marks

Soothing Moderate

Ingredients aimed at visible redness and reactivity

Cell renewal Low

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling Low

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (8)

Supporting ingredients (47)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Butylene Glycol Glycerin Dimethicone Ethylhexyl Stearate 1,2-hexanediol Hydroxyethyl Acrylate/sodium Acryloyldimethyl Taurate Copolymer Cetearyl Alcohol Betaine Glyceryl Polymethacrylate Glyceryl Stearate Acrylates/c10-30 Alkyl Acrylate Crosspolymer Dimethicone/vinyl Dimethicone Crosspolymer Dimethiconol Hydrogenated Lecithin Cellulose Gum Glyceryl Caprylate Glucosyl Hesperidin Stearic Acid Tromethamine Polyglyceryl-3 Methylglucose Distearate Palmitic Acid Sorbitan Isostearate Ethylhexylglycerin Dimethyl Isosorbide Adenosine Sodium Polyacrylate Sodium Metaphosphate Polyglyceryl-6 Caprylate Hydroxypropyl Bispalmitamide MEA Mannitol Myristic Acid Acrylates/ammonium Methacrylate Copolymer Lauric Acid Thymol Trimethoxycinnamate Cholesterol Silica Oleanolic Acid Caprylyl Glycol Pullulan Acetyl Heptapeptide-4 Zein Pectin Hydrolyzed Extensin Simmondsia Chinensis Seed Oil Sodium Hydroxide Polyglyceryl-10 Laurate

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • Essential-oil-free
  • No drying alcohol
  • Paraben-free
  • Microplastic-free
  • Sulfate-free
  • Dye-free
  • No animal-derived ingredients

Contains

  • Silicones

    Dimethicone, Dimethicone/vinyl Dimethicone Crosspolymer, Dimethiconol

  • Facial oils

    Simmondsia Chinensis Seed Oil

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Retinoids (retinol, retinal)
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • AHAs (glycolic, lactic)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • BHA (salicylic acid)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • PHAs (gluconolactone)

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Benzoyl peroxide

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Vitamin C (L-ascorbic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • Azelaic acid

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Eye
  4. Moisturise
  5. Protect

This product is the "Eye" step.

  • Tap along the orbital bone with your ring finger; product migrates upward on its own.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Contains Hydroxypinacolone Retinoate, usually reviewed with a doctor during pregnancy.
Fungal acne (malassezia)
8 ingredients could feed malassezia: Ethylhexyl Stearate, Glyceryl Stearate, Glyceryl Caprylate, Polyglyceryl-3 Methylglucose Distearate, Sorbitan Isostearate, Polyglyceryl-6 Caprylate, Simmondsia Chinensis Seed Oil, Polyglyceryl-10 Laurate. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 55 ingredients on the label.

17
Texture agent

Sets the thickness, spread and stability of the formula

13
Emollient

Softens and smooths by filling gaps between skin cells

12
Surfactant

Lifts oil and dirt, or holds oil and water together

10
Humectant

Draws water into the upper layers of skin

9
Occlusive

Forms a film that slows water loss

8
Active

Changes how skin behaves rather than how it feels

5
Solvent

Dissolves and carries everything else

4
pH adjuster

Sets the acidity the formula needs to work

3
Peptide

Amino-acid chains that signal for repair or firmness

2
Chelator

Binds trace metals that would otherwise spoil the formula

1
Antioxidant

Neutralises free radicals from UV and pollution

1
Exfoliant

Loosens or dissolves dead surface cells

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Butylene Glycol Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
3 Glycerin Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
4 Dimethicone Emollient
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Occlusive

4th on the list, which puts it at an estimated 2–10% of the formula.

Dimethicone

Hydration Silicone
7 scientific references
  • FDA Code of Federal Regulations, April 2020, ePublication
  • International Journal of Toxicology, May 2014, pages 65S-115S
  • The Journal of Clinical and Aesthetic Dermatology, May 2014, pages 36-44
  • Dermatologic Therapy, May 2012, pages 229-233
  • Clinics in Dermatology, May-June 2012, pages 345-348
  • International Journal of Cosmetic Science, January 2008, pages 19-33
  • Skin Research and Technology, May 2000, pages 77-80
5 Niacinamide Active
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

5th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

6th on the list, which puts it at an estimated 2–10% of the formula.

2-Ethylhexyl stearate

Hydration
2 scientific references
  • PubChem, Accessed November 2021, ePublication
  • CosmeticsInfoorg, Accessed Novembe 2021, ePublication
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

7th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

8th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium hydroxyethyl acrylate and acryloyldimethyl taurate monomers

Synthetic polymer
9 Cetearyl Alcohol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant, Texture agent

9th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Alcohols, C16-18

Hydration
4 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • FDA Cosmetic Labeling Claims, August 2020, ePublication
  • Journal of the Society of Cosmetic Scientists of Korea, June 2009, pages 103-110
  • Journal of the American College of Toxicology, 1988, pages 359-413
10 Betaine Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Texture agent

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt

Hydration
5 scientific references
  • International Journal of Toxicology, 2018, pages 28S-46S
  • Food Science and Biotechnology, October 2017, pages 1391-1397
  • The Journal of Chemical Physics, June 2015, ePublication
  • The American Journal of Clinical Nutrition, September 2004, pages 539-549
  • Skin Research and Technology, February 2003, pages 50-58
11 Panthenol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, 2-methyl-, homopolymer, ester with 1,2,3-propanetriol

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
14 Glyceryl Stearate Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Stearic acid, monoester with glycerol

Hydration
3 scientific references
  • Cosmeticsinfoorg, Accessed November 2021, ePublication
  • Drugs in Context, April 2018, pages 1-14
  • International Journal of Toxicology, May 2007, pages 1–30
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dimethicone/Vinyl Dimethicone Crosspolymer is a crosslinked dimethyl siloxane polymer (silicone elastomer) that is formed by the reaction between Hydrogen Dimethicone or Bis-Hydrogen Dimethicone, and Vinyl Dimethicone or Bis-Vinyldimethicone.

Silicone
17 Dimethiconol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Emollient

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Poly[oxy(dimethylsilylane)], .alpha.-hydro-.omega.-hydroxy-

Hydration
3 scientific references
  • CosmeticsInfoorg, Accessed September 2021, ePublication
  • International Journal of Toxicology, November 2017, pages 31S-50S
  • International Journal of Cosmetic Science, April 2005, page 139
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, hydrogenated

Hydration
4 scientific references
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Nanocosmetics, June 2019, pages 95–140
  • Current Drug Delivery, 2016, pages 111–120
  • Pharmaceutical Research, February 2013, pages 538–55
19 Cellulose Gum Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cellulose, carboxymethyl ether, sodium salt

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Octanoic acid, monoester with glycerol

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

(S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether

Anti-Aging
22 Stearic Acid Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant, Texture agent

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Stearic acid

Hydration
4 scientific references
  • Cosmetic Ingredient Review, May 2019, pages 1-61
  • International Journal of Cosmetic Science, August 2008, page 310
  • Therapeutics for the Clinician, May 2005, pages 317-324
  • Journal of Cosmetic Science, December 2003, pages 559-568
23 Tromethamine pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Methyl-D-glucopyranoside, ethers with 1,2,3-propanetriol homopolymer, octadecanoates (1:1:2) (3 mol glycerol average molar ratio)

25 Palmitic Acid Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hexadecanoic acid

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sorbitan, isooctadecanoate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
28 Dimethyl Isosorbide Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Solvent

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Occlusive, Texture agent

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Propenoic acid, homopolymer, sodium salt

Oil Control Synthetic polymer
7 scientific references
  • International Food Research Journal, February 2021, pages 44 - 55
  • Journal of Nanoscience and Nanotechnology, March 2018, pages 1, 611-1, 614
  • Industrial & Engineering Chemistry Research, November 2014, pages 18, 346-18, 351
  • Journal of Applied Polymer Science, November 2001, pages 1, 515-1, 520
  • United States Patent, April 2000, ePublication
  • https://wwwsocochemcom/is-sodium-polyacrylate-safehtml
  • https://wwwcir-safetyorg/sites/default/files/acryco092018TARpdf
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Chelator, pH adjuster

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium metaphosphate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ester of hexaglycerol and caprylic acid

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Propanediamino, 2-hydroxy-, N,N'-bis(1-oxohexadecyl)-N,N'-bis(2-hydroxyethyl)-

34 Mannitol Humectant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Texture agent

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

D-Mannitol

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Anti-Acne Anti-Aging Evens Skin Tone
36 Myristic Acid Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Tetradecanoic acid

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3-O-Ethyl Ascorbic Acid is the organic compound.

Anti-Aging Evens Skin Tone Dark Spot Fading
5 scientific references
  • Free Radical Biology and Medicine, September 2021, pages 151–169
  • Life, May 2021, pages 1–13
  • International Journal of Pharmaceutics, December 2019, pages 1–9
  • Journal of Cosmetic Science, July-August 2018, pages 233–243
  • AAPS PharmSciTech, June 2016, pages 767–777
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ammonium butenoate, polymer with propenoic acid, butenoic acid, and/or alkyl propenoates

Synthetic polymer
39 Lauric Acid Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dodecanoic acid

Hydration Soothing
5 scientific references
  • Dermatologic Therapy, July 2020, pages 1-4
  • IOP Conference Series: Earth and Environmental Science, June 2020, pages 1-6
  • Biomaterials, October 2009, pages 6, 035-6, 040
  • Journal of the American college of Toxicology, 1987, pages 1-81
  • Tenside Surfactants Detergents, December 1976, pages 313-316
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Antioxidant

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Thymol Trimethoxycinnamate

41 Cholesterol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant, Texture agent

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cholest-5-en-3-ol (beta)-

Hydration Anti-Aging
4 scientific references
  • Frontiers in Bioengineering and Biotechnology, August 2015, pages 1-6
  • Journal of Cosmetic Dermatology, July 2007, pages 239-242
  • Journal of Structural Biology, June 2007, pages 386-400
  • International Journal of Toxicology, 2006, pages 1-89
42 Silica Exfoliant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Exfoliant, Texture agent

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Silicon dioxide

Oil Control
6 scientific references
  • Advances in Colloid and Interface Science, July 2021, page 10, 2437
  • Cosmetic Ingredient Review, October 2019, pages 1-34
  • Nanomedicine, August 2019, pages 2, 243-2, 267
  • Biological and Pharmaceutical Bulletin, 2016, pages 1, 201-1, 205
  • European Journal of Pharmaceutics and Biopharmaceutics, January 2015, pages 116-125
  • Cosmetics & Toiletries, April 2015, pages 36-45
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3beta-Hydroxyolean-12-en-28-oic acid

Soothing
3 scientific references
  • European Journal of Pharmaceutical Sciences, October 2012, pages 549-555
  • Folio Histochemica et Cytobiologica, Volume 4, 2011, pages 664-669
  • Journal of Ethnopharmacology, December 1995, pages 57-68
44 Caprylyl Glycol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Octane-1,2-diol

45 Pullulan Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Pullulan is a polysaccharide produced from starch by cultivating the yeast, Aureobasidium pullulans

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Peptide

46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Acetyl Heptapeptide-4 is the reaction product of acetic acid and Heptapeptide-4

47 Zein Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Zeins. A protein derived from Zea mays, Gramineae. It belongs to the prolamine class and contains seventeen amino acids

48 Pectin Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Pectin

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active, Peptide

49th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Acetyl hexapeptide-8 is the synthetic peptide consisting of arginine, methionine, and acetylated glutamic acid residues

Anti-Aging Hydration
6 scientific references
  • Cosmetics, November 2020, Issue 7, Volume 4, page 91
  • La Clinica Terapeutica, November 2020, pages e539-e548
  • https://wwwcir-safetyorg/sites/default/files/AcetylHexapeptide-8pdf
  • Cutaneous and Ocular Toxicology, March 2015, pages 46-52
  • European Journal of Pharmaceutical Sciences, February 2015, pages 27-35
  • Dermatologic Therapy, September-October 2007, issue 5, pages 343-349
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

50th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycoproteins (specific or class), extensins, hydrolyzates

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

51st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Simmondsia Chinensis Seed Oil is the fixed oil expressed or extracted from seeds of the desert shrub, Jojoba, Simmondsia chinensis, Buxaceae

52 Sodium Hydroxide pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

52nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium hydroxide

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

53rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio)

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active, Peptide

54th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Acetyl Octapeptide-3 is the reaction product of acetic acid and Octapeptide-3

Anti-Aging Hydration
8 scientific references
  • 5 Super Anti-Aging Antioxidants Your Skin Needs
  • How to Keep Your Neck & Chest Looking Young
  • Acne & Aging Skin
  • How to Diminish Uneven Skin Tone and Get Your Glow Back
  • What Are Peptides and What Do They Do for Skin?
  • The Truth About Firming Creams
  • Top 5 Reasons to Add Antioxidants to Your Skin Care Routine
  • Anti-Aging Superstars
55 Citric Acid Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Chelator, pH adjuster

55th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-Hydroxy-1,2,3-propanetricarboxylic acid

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Frequently asked questions

What ingredients are in Regederm 365 Retinoid Eye Serum?

WATER, BUTYLENE GLYCOL, GLYCERIN, DIMETHICONE, NIACINAMIDE, ETHYLHEXYL STEARATE, 1,2-HEXANEDIOL, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, CETEARYL ALCOHOL, BETAINE, PANTHENOL, GLYCERYL POLYMETHACRYLATE, SODIUM HYALURONATE, GLYCERYL STEARATE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, DIMETHICONOL, HYDROGENATED LECITHIN, CELLULOSE GUM, GLYCERYL CAPRYLATE, GLUCOSYL HESPERIDIN, STEARIC ACID, TROMETHAMINE, POLYGLYCERYL-3 METHYLGLUCOSE DISTEARATE, PALMITIC ACID, SORBITAN ISOSTEARATE, ETHYLHEXYLGLYCERIN, DIMETHYL ISOSORBIDE, ADENOSINE, SODIUM POLYACRYLATE, SODIUM METAPHOSPHATE, POLYGLYCERYL-6 CAPRYLATE, HYDROXYPROPYL BISPALMITAMIDE MEA, MANNITOL, HYDROXYPINACOLONE RETINOATE, MYRISTIC ACID, 3-O-ETHYL ASCORBIC ACID, ACRYLATES/AMMONIUM METHACRYLATE COPOLYMER, LAURIC ACID, THYMOL TRIMETHOXYCINNAMATE, CHOLESTEROL, SILICA, OLEANOLIC ACID, CAPRYLYL GLYCOL, PULLULAN, ACETYL HEPTAPEPTIDE-4, ZEIN, PECTIN, ACETYL HEXAPEPTIDE-8, HYDROLYZED EXTENSIN, SIMMONDSIA CHINENSIS SEED OIL, SODIUM HYDROXIDE, POLYGLYCERYL-10 LAURATE, ACETYL OCTAPEPTIDE-3, CITRIC ACID.

What are the active ingredients in Regederm 365 Retinoid Eye Serum?

NIACINAMIDE, PANTHENOL, SODIUM HYALURONATE, HYDROXYPINACOLONE RETINOATE, 3-O-ETHYL ASCORBIC ACID, ACETYL HEXAPEPTIDE-8, ACETYL OCTAPEPTIDE-3, CITRIC ACID.

How do I use Regederm 365 Retinoid Eye Serum?

In the evening, apply a small amount around the eye area using your ring finger. Gently pat until absorbed. Follow with moisturizer. Use sunscreen during the day when using retinoids.

What skin types is Regederm 365 Retinoid Eye Serum good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is Regederm 365 Retinoid Eye Serum good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is Regederm 365 Retinoid Eye Serum fungal acne safe?

8 ingredients could feed malassezia: Ethylhexyl Stearate, Glyceryl Stearate, Glyceryl Caprylate, Polyglyceryl-3 Methylglucose Distearate, Sorbitan Isostearate, Polyglyceryl-6 Caprylate, Simmondsia Chinensis Seed Oil, Polyglyceryl-10 Laurate. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use Regederm 365 Retinoid Eye Serum while pregnant?

It contains Hydroxypinacolone Retinoate, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.

Is Regederm 365 Retinoid Eye Serum fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does Regederm 365 Retinoid Eye Serum contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is Regederm 365 Retinoid Eye Serum silicone free?

No — it contains Dimethicone, Dimethicone/vinyl Dimethicone Crosspolymer, Dimethiconol.

Does Regederm 365 Retinoid Eye Serum contain essential oils?

No. Reading the full ingredient list, this formula is essential-oil-free.

Is Regederm 365 Retinoid Eye Serum paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with Regederm 365 Retinoid Eye Serum?

It layers well with Retinoids (retinol, retinal), Copper peptides, Bakuchiol, Niacinamide, Hyaluronic acid, Ceramides. Take more care combining it with AHAs (glycolic, lactic), BHA (salicylic acid), PHAs (gluconolactone), Benzoyl peroxide, Vitamin C (L-ascorbic acid), Azelaic acid — use them in separate routines or on alternate days.

When should I apply Regederm 365 Retinoid Eye Serum?

Use it morning and evening, before moisturiser.

How many ingredients does Regederm 365 Retinoid Eye Serum have?

It lists 55 ingredients, of which 8 are recorded as actives.

Who makes Regederm 365 Retinoid Eye Serum?

Aestura, a brand based in Korea.

Brand
Aestura
Country
Korea

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