Numbuzin No.5+ Glutathione Vitamin Dark Spot Cream

Numbuzin

No.5+ Glutathione Vitamin Dark Spot Cream

face cream

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Fit by skin type

General, ingredient-based — not your personalized match.

Dry
61%
Combination (dry)
61%
Balanced
91%
Combination (oily)
79%
Oily
79%

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70
Ingredients
7
Benefits
6
Actives
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Nourishing moisturizer with antioxidants, skin repairing and regenerating ingredients, deeply moisturizes and strengthens skin barrier while gently fading hyperpigmentation and dark spots for rejuvenated, blemish-free complexion.

Key Insights

Benefits

7
Anti-Aging
Dark Spot Fading
Evens Skin Tone
Hydration
Oil Control
Pore Minimizer
Soothing

Active Ingredients

6
Ceramides Hyaluronic acid Recombinant peptides Vitamin B3 (niacinamide) Vitamin B5 (panthenol) Vitamin C

Risks

3
Microplastic
Silicone
Synthetic polymer

Full Ingredients

70 total
WATER DIPROPYLENE GLYCOL GLYCERIN NIACINAMIDE Vitamin B3 (niacinamide) OCTYLDODECANOL HELIANTHUS ANNUUS SEED OIL BUTYLENE GLYCOL TREHALOSE PENTYLENE GLYCOL 1,2-HEXANEDIOL CAPRYLYL METHICONE PANTHENOL Vitamin B5 (panthenol) POLYMETHYLSILSESQUIOXANE PROPANEDIOL HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER CETEARYL OLIVATE POLYGLYCERYL-10 BEHENATE/EICOSADIOATE AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER SORBITAN OLIVATE ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER TROMETHAMINE XANTHAN GUM C12-16 ALCOHOLS ETHYLHEXYLGLYCERIN SORBITAN ISOSTEARATE ADENOSINE ERIOBOTRYA JAPONICA LEAF EXTRACT PALMITIC ACID HYDROGENATED LECITHIN GLUTATHIONE PHOSPHATIDYLCHOLINE POLYGLYCERYL-10 LAURATE DILAURYL THIODIPROPIONATE PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE SODIUM PHYTATE COPTIS JAPONICA ROOT EXTRACT ALLANTOIN MENTHA VIRIDIS EXTRACT MADECASSOSIDE LECITHIN CELLULOSE SODIUM PHOSPHATE SODIUM HYALURONATE Hyaluronic acid POLYGLUTAMIC ACID DEXTRIN THEOBROMA CACAO EXTRACT ASIATICOSIDE CENTELLA ASIATICA LEAF EXTRACT CYSTEINE TOCOPHEROL 3-O-ETHYL ASCORBIC ACID Vitamin C ARBUTIN BISABOLOL SH-OLIGOPEPTIDE-1 Recombinant peptides SH-OLIGOPEPTIDE-2 Recombinant peptides SH-POLYPEPTIDE-1 Recombinant peptides SH-POLYPEPTIDE-10 Recombinant peptides SH-POLYPEPTIDE-11 Recombinant peptides SH-POLYPEPTIDE-3 Recombinant peptides SH-POLYPEPTIDE-59 Recombinant peptides SH-POLYPEPTIDE-9 Recombinant peptides ARGANIA SPINOSA KERNEL OIL CHOLESTEROL SESAMUM INDICUM SEED OIL CHITOSAN SERENOA SERRULATA FRUIT EXTRACT ASCORBIC ACID Vitamin C BETA-SITOSTEROL ASCORBYL GLUCOSIDE Vitamin C CERAMIDE NP Ceramides

About No.5+ Glutathione Vitamin Dark Spot Cream

Overview

No.5+ Glutathione Vitamin Dark Spot Cream is a lightweight cream from Numbuzin, a brand based in Korean. The formula is built mainly around hydration and soothing. The ingredient list runs to 70 ingredients, each broken down in full below.

Texture and finish

By its ingredient list the formula reads as light: water and humectants lead, with emollients kept lower in the order. It contains both silicones and oils, a combination that usually finishes smooth and slightly satin and sits well under makeup. Hydration is handled by Glycerin, Butylene Glycol and Trehalose, humectants that pull water into the upper layers of skin rather than sealing it there.

What the formula does

Hydration: Very high. Ingredients that pull and hold water in the upper layers of skin, and here that comes from Glycerin, Butylene Glycol, Trehalose and Panthenol.

Soothing: High. Ingredients aimed at visible redness and reactivity, and here that comes from Panthenol, Polyglyceryl-10 Behenate/eicosadioate, Allantoin and Madecassoside.

Barrier support: Moderate. Lipids and repair signals that support skin barrier integrity, and here that comes from Niacinamide, Panthenol, Hydrogenated Lecithin and Madecassoside.

Brightening: Moderate. Ingredients that act on uneven tone and post-inflammatory marks, and here that comes from Niacinamide, 3-o-ethyl Ascorbic Acid, Arbutin and Ascorbic Acid.

Who it suits

On richness alone it suits Balanced skin best, and is the least natural fit for Dry and Combination (dry) skin. Nothing in the list is flagged as a common irritant, which is a reasonable starting point for reactive skin — though a patch test is still the only way to know.

What it does not target

The formula contributes little or nothing on cell renewal. That is not a fault — most products are not meant to do everything — but if one of those is your priority, this is not the product that will address it.

What is not in it

Reading the full list, the formula is fragrance-free, no drying alcohol, paraben-free, sulfate-free, dye-free and no animal-derived ingredients. Those claims come from the ingredient list itself, not from the packaging. It does contain essential oils, worth knowing if your skin reacts to any of them.

Where it fits in a routine

It can be used morning and evening. In a routine it goes after serums. Seal in your serums with it; in the morning, sunscreen still goes on top.

This summary is generated from the product's ingredient list. It is not a review, it is not the brand's own marketing claims, and it does not replace advice from a dermatologist.

Pros and cons

Drawn purely from the ingredient list

Pros

  • No fragrance or declared allergens
  • No drying alcohol
  • Strong humectant content for hydration
  • Several soothing ingredients
  • No common irritants flagged in the list

Things to know

  • Contains essential oils, a common source of reactivity
  • Contains a solid synthetic polymer (microplastic)
  • 8 ingredients could feed malassezia (fungal acne)
  • Contains ingredients usually flagged for review during pregnancy

Which skin types it suits

Scored on how rich or light the formula reads from its INCI order.

Suitable for

  • Balanced skin

May suit

  • Combination (oily) skin
  • Oily skin

Less suitable for

  • Dry skin
  • Combination (dry) skin

Sensitive skin

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Skin concerns

Based on the curated benefits documented for this product's ingredients.

Helps with

  • Hydration 23 ingredients

    Attracts and locks in moisture to keep skin plump and dewy

  • Anti-Aging 17 ingredients

    Boosts collagen and cell turnover to reduce fine lines and wrinkles

  • Soothing 10 ingredients

    Calms redness, irritation, and inflammation for sensitive skin

  • Dark Spot Fading 5 ingredients

    Fades hyperpigmentation and evens out dark spots over time

  • Evens Skin Tone 5 ingredients

    Brightens and balances complexion for a more uniform appearance

  • Oil Control 1 ingredient

    Regulates sebum production to reduce shine and greasiness

  • Pore Minimizer 1 ingredient

    Tightens and refines the look of enlarged pores

Does not target

Anti-Acne Blackhead Reducing Smooths Bumpy Skin

None of the ingredients in this formula are associated with these benefits. This is not unusual, as most products are designed to target a limited number of concerns.

Key ingredients

The actives, UV filters and benefit-carrying ingredients in this formula, in the order they are listed.

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration

3rd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
Niacinamide Vitamin B3 (niacinamide)

4th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer

5th on the list, which puts it at an estimated 2–10% of the formula.

2-Octyldodecan-1-ol

Hydration

6th on the list, which puts it at an estimated 2–10% of the formula.

Helianthus Annuus Seed Oil is the oil expressed from the seeds of the Sunflower, Helianthus annuus L., Compositae

Anti-Aging Hydration

7th on the list, which puts it at an estimated 1–5% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration

8th on the list, which puts it at an estimated 1–5% of the formula.

alpha-D-Glucopyranoside, alpha-D-glucopyranosyl

Hydration

9th on the list, which puts it at an estimated 1–5% of the formula.

1,2-Dihydroxypentane

Hydration

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,1,3,5,5,5-Heptamethyl-3-octyl-trisiloxane

Hydration
Panthenol Vitamin B5 (panthenol)

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-dihydroxypropane

Hydration

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cetearyl Olivate is the ester of Cetearyl Alcohol and the fatty acids derived from olive oil

Hydration

Formula analysis

Each axis is scored from the ingredients present and how high up the list they sit.

Hydration Very high

Ingredients that pull and hold water in the upper layers of skin

Barrier support Moderate

Lipids and repair signals that support skin barrier integrity

Antioxidant support Low

Ingredients that mop up free radicals from UV and pollution

Oil control Moderate

Ingredients that moderate sebum or absorb shine

Brightening Moderate

Ingredients that act on uneven tone and post-inflammatory marks

Soothing High

Ingredients aimed at visible redness and reactivity

Cell renewal None

Retinoids, acids and enzymes that speed surface turnover

Firmness signalling Moderate

Peptides and growth factors that signal for collagen support

Active and supporting ingredients

"Active" here means an ingredient carrying a recorded active type or a recognised UV filter.

Active ingredients (15)

Supporting ingredients (55)

Solvents, emollients, texture agents and preservatives — the formula that carries the actives.

Water Dipropylene Glycol Glycerin Octyldodecanol Helianthus Annuus Seed Oil Butylene Glycol Trehalose Pentylene Glycol 1,2-hexanediol Caprylyl Methicone Polymethylsilsesquioxane Propanediol Hydroxyethyl Acrylate/sodium Acryloyldimethyl Taurate Copolymer Cetearyl Olivate Polyglyceryl-10 Behenate/eicosadioate Ammonium Acryloyldimethyltaurate/vp Copolymer Sorbitan Olivate Acrylates/c10-30 Alkyl Acrylate Crosspolymer Tromethamine Xanthan Gum C12-16 Alcohols Ethylhexylglycerin Sorbitan Isostearate Adenosine Eriobotrya Japonica Leaf Extract Palmitic Acid Hydrogenated Lecithin Glutathione Phosphatidylcholine Polyglyceryl-10 Laurate Dilauryl Thiodipropionate Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate Sodium Phytate Coptis Japonica Root Extract Allantoin Mentha Viridis Extract Madecassoside Lecithin Cellulose Sodium Phosphate Polyglutamic Acid Dextrin Theobroma Cacao Extract Asiaticoside Centella Asiatica Leaf Extract Cysteine Tocopherol Arbutin Bisabolol Argania Spinosa Kernel Oil Cholesterol Sesamum Indicum Seed Oil Chitosan Serenoa Serrulata Fruit Extract Beta-sitosterol

What is and is not in it

Read from the full ingredient list. A brand's own claim may differ.

Free from

  • Fragrance-free
  • No drying alcohol
  • Paraben-free
  • Sulfate-free
  • Dye-free
  • No animal-derived ingredients

Contains

  • Essential oils

    Mentha Viridis Extract

  • Silicones

    Caprylyl Methicone, Polymethylsilsesquioxane

  • Microplastics

    Polymethylsilsesquioxane

  • Facial oils

    Helianthus Annuus Seed Oil, Argania Spinosa Kernel Oil, Sesamum Indicum Seed Oil

What to layer it with

Judged by the same curated rules our routine checker uses. It reads the ingredients, not the label.

Compatible with

  • Vitamin C (L-ascorbic acid)
  • PHAs (gluconolactone)
  • Azelaic acid
  • Copper peptides
  • Bakuchiol
  • Niacinamide
  • Hyaluronic acid
  • Ceramides
  • Signal peptides
  • Panthenol
  • Sunscreen

Use with caution

  • Benzoyl peroxide

    Best kept to separate routines — one in the morning, one at night, or on alternate days.

  • Retinoids (retinol, retinal)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • AHAs (glycolic, lactic)

    Can be layered, but the combination raises the irritation risk. Go slowly.

  • BHA (salicylic acid)

    Can be layered, but the combination raises the irritation risk. Go slowly.

Where it fits in a routine

Morning Evening
  1. Cleanse
  2. Toning
  3. Treat
  4. Moisturise
  5. Protect

This product is the "Moisturise" step.

  • Seal in your serums with it; in the morning, sunscreen still goes on top.

Safety and suitability

Flags to check, not verdicts. None of this is medical advice — if you are pregnant, breastfeeding or treating a skin condition, ask a doctor.

Pregnancy and breastfeeding
Contains Arbutin, usually reviewed with a doctor during pregnancy.
Fungal acne (malassezia)
8 ingredients could feed malassezia: Helianthus Annuus Seed Oil, Cetearyl Olivate, Polyglyceryl-10 Behenate/eicosadioate, Sorbitan Olivate, Sorbitan Isostearate, Polyglyceryl-10 Laurate, Argania Spinosa Kernel Oil, Sesamum Indicum Seed Oil. That is about the yeast's food supply, not a prediction that you will break out.
Sensitive and reactive skin
No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.
Recorded ingredient risks
Microplastic, Silicone, Synthetic polymer

Ingredients by function

Most ingredients do more than one job, so these counts add up to more than the 70 ingredients on the label.

15
Active

Changes how skin behaves rather than how it feels

14
Texture agent

Sets the thickness, spread and stability of the formula

9
Antioxidant

Neutralises free radicals from UV and pollution

9
Surfactant

Lifts oil and dirt, or holds oil and water together

8
Emollient

Softens and smooths by filling gaps between skin cells

8
Peptide

Amino-acid chains that signal for repair or firmness

8
Solvent

Dissolves and carries everything else

6
Occlusive

Forms a film that slows water loss

6
Plant extract

Botanical material, usually for antioxidants or scent

4
Humectant

Draws water into the upper layers of skin

3
pH adjuster

Sets the acidity the formula needs to work

2
Soothing

Calms visible redness and irritation

1
Chelator

Binds trace metals that would otherwise spoil the formula

Ingredient breakdown

Every ingredient on the label, in order, with what it does and roughly how much of it is likely to be there.

1 Water Solvent
Estimated level
30–80%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

1st on the list, which puts it at an estimated 30–80% of the formula.

Aqua (EU),Deionized Water,Distilled Water,Micromatrix Fractile AN,Onsen-Sui (JPN),Purified Water

Hydration
3 scientific references
  • Skin Research and Technology, May 2015, pages 131-136
  • Skin Pharmacology and Applied Skin Physiology, November-December 1999, pages 344-351
  • Journal of Cosmetic Science, September-October 1993, pages 249-262
2 Dipropylene Glycol Texture agent
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Texture agent, Solvent

2nd on the list, which puts it at an estimated 5–20% of the formula.

1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol

3 Glycerin Humectant
Estimated level
5–20%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Occlusive, Texture agent, Solvent

3rd on the list, which puts it at an estimated 5–20% of the formula.

Glycerine ;Glycerol (INN); Glycerol (RIFM); Glycerolum (EP); Glycyl Alcohol; 1,2,3-Propanetriol; 1,2,3-Trihydroxypropane

Hydration Anti-Aging
6 scientific references
  • Journal of Pharmaceutical Investigation, March 2021, pages 223-231
  • International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
  • International Journal of Cosmetic Science, August 2016, ePublication
  • British Journal of Dermatology, July 2008, pages 23-34
  • Journal of Cosmetic Dermatology, June 2007, pages 75-82
  • Proceedings of the National Academy of Sciences, June 2003, pages 7, 360-7, 365
4 Niacinamide Active
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Active

4th on the list, which puts it at an estimated 2–10% of the formula.

Niacinamide (vitamin B3) is a gentle skincare active that repairs the skin barrier, calms redness, controls oil and evens tone at 2–5%. Official IUPAC name: **3-Pyridinecarboxamide**

Soothing Anti-Aging Pore Minimizer
15 scientific references
  • International Journal of Dermatology, February 2021, pages 166-173
  • Biomolecules & Therapeutics, July 2019, pages 562-569
  • Experimental Dermatology, February 2019, pages 15-22
  • Dermatologic Therapy, September 2017, ePublication
  • Journal of Investigative Dermatology, May 2017, page S116
  • International Journal of Pharmaceutics, March 2017, pages 158-162
  • Facial Plastic Surgery Clinics of North America, May 2016, pages 145-152
  • Clinical, Cosmetic, and Investigational Dermatology, July 2015, pages 405-412
  • Skin Pharmacology and Physiology, June 2014, pages 311-315
  • International Journal of Pharmacy, January 2013, pages 192-201
  • Dermatoendrocrinology, July 2012, pages 308-319
  • International Journal of Toxicology, September 2005, pages 1-31
  • Dermatologic Surgery, July 2005, pages 860-865
  • International Journal of Cosmetic Science, October 2004, pages 231-238
  • Journal of Cosmetic Dermatology, April 2004, pages 88-93
5 Octyldodecanol Emollient
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient, Solvent

5th on the list, which puts it at an estimated 2–10% of the formula.

2-Octyldodecan-1-ol

Hydration
Estimated level
2–10%
Confidence
Moderate — INCI order above the 1% line
Roles
Emollient

6th on the list, which puts it at an estimated 2–10% of the formula.

Helianthus Annuus Seed Oil is the oil expressed from the seeds of the Sunflower, Helianthus annuus L., Compositae

Anti-Aging Hydration
4 scientific references
  • Pediatric Dermatology, August 2018, ePublication; and January-February 2013, pages 42-50
  • Chemicke Zvesti, May 2018, pages 2, 607-2, 615
  • International Journal of Molecular Sciences, December 2017, ePublication
  • Dermatology, October 2014, pages 230-239
7 Butylene Glycol Humectant
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant, Texture agent, Solvent

7th on the list, which puts it at an estimated 1–5% of the formula.

Butane-1,3-diol (CAS No. 107-88-0/ EC No. 203-529-7) (R)-(-)-butane-1,3-diol” (CAS No. 6290-03-5/ EC No. 228-532-0)

Hydration
5 scientific references
  • CosmeticsInfoorg, Accessed March 2021, ePublication
  • US Food and Drug Administration Code of Federal Regulations</em>, Accessed March 2021, ePublication
  • International Journal of Toxicology, May 2011, pages 5S-16S
  • Skin Research and Technology, November 2007, pages 417-24
  • Journal of the American College of Toxicology, September 1985, pages 223-248
8 Trehalose Humectant
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Humectant

8th on the list, which puts it at an estimated 1–5% of the formula.

alpha-D-Glucopyranoside, alpha-D-glucopyranosyl

Hydration
7 scientific references
  • Cosmetics, October 2019, pages 1-10
  • Cell Death & Disease, July 2019, pages 1-16
  • International Journal of Toxicology, 2019, pages 5S-38S
  • Applied Microbiology and Biotechnology, February 2018, pages 2, 965-2, 976
  • Journal of Applied Polymer Science, May 2017, pages 1-6
  • Biomedical Reports, September 2014, pages 755-759
  • Journal of Pharmaceutical Sciences, June 2011, pages 2, 020-2, 053
Estimated level
1–5%
Confidence
Moderate — INCI order above the 1% line
Roles
Solvent

9th on the list, which puts it at an estimated 1–5% of the formula.

1,2-Dihydroxypentane

Hydration
4 scientific references
  • https://thedermreviewcom/pentylene-glycol/
  • Regulatory Toxicology and Pharmacology, July 2017, pages 106-111
  • Prospector, June 2015, ePublication
  • International Journal of Toxicology, October 2012, pages 147S-168S
10 1,2-hexanediol Solvent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Solvent

10th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

11th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,1,1,3,5,5,5-Heptamethyl-3-octyl-trisiloxane

Hydration Silicone
12 Panthenol Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

12th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (2R)-; dl-Panthenol

Hydration Soothing
7 scientific references
  • The Linus Pauling Institute, Oregon State University, Accessed April 2021, ePublication
  • International Journal of Cosmetic Science, December 2019, pages 534-547
  • Journal of Cosmetic Dermatology, January 2019, pages 346-354
  • Cosmetic Ingredient Review, March 2018, pages 1-51
  • The Journal of Dermatological Treatment, August 2017, pages 173-180
  • Journal of Cosmetic Science, August 2011, pages 361-370
  • American Journal of Clinical Dermatology, Volume 3, 2002, pages 427-433
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

13th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Polymer formed by hydrolysis and condensation of methyltrimethoxysilane

Microplastic
14 Propanediol Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent, Solvent

14th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-dihydroxypropane

Hydration
4 scientific references
  • PubChem Compound Summary, April 2021, ePublication
  • SpecialChem, Accessed April 2021, ePublication
  • Cosmetic Ingredient Review, June 2018, pages 1-73
  • Cosmetics & Toiletries, May 2013, pages 81-86
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

15th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium hydroxyethyl acrylate and acryloyldimethyl taurate monomers

Synthetic polymer
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

16th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cetearyl Olivate is the ester of Cetearyl Alcohol and the fatty acids derived from olive oil

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

17th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ester of decaglycerol and behenic/eicosadioic acids

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

18th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of ammonium acryloyldimethyltaurate and vinylpyrrolidone monomers

Hydration
19 Sorbitan Olivate Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

19th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

D-Glucitol, 1,4-Anhydro-, 6-monoester with olive oil fatty acids

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Texture agent

20th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

C10-30 alkyl propenoate, polymer with propenoic acid, butenoic acidand/or alkyl propenoates, product with propenyl sucrose ether or propenyl 2,2-dihydroxymethyl-1,3-propanediol

Synthetic polymer
21 Tromethamine pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

21st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

22 Xanthan Gum Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant, Texture agent

22nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Xanthan gum

23 C12-16 Alcohols Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Texture agent

23rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Alcohols, C12-16

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

24th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2-Propanediol, 3-(2-ethylhexyloxy)

Hydration
5 scientific references
  • PLoS One, October 2016, ePublication
  • Contact Dermatitis, May 2016, pages 281-288
  • International Journal of Toxicology, September 2013, pages 5S-21S
  • Personal Care, 2008, pages 1-4
  • Cosmetic Science Technology, 2006, pages 1-11
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

25th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sorbitan, isooctadecanoate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

26th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

6-Amino-9-beta-D-ribofuranosyl-9H-purine

Soothing
8 scientific references
  • PubChem, Accessed May 2021, ePublication
  • Cosmetic Ingredient Review, September 2020, pages 1-38
  • Experimental Dermatology, August 2014, pages 553-554
  • Journal of Investigative Dermatology, August 2011, pages 526-546
  • International Journal of Cosmetic Science, December 2006, pages 447-451
  • British Journal of Pharmacology, October 2008, issue 4, pages 475-486
  • PloS One, May 2008 (ePublication)
  • >International Journal of Cosmetic Science, August 2006, pages 447-451
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Plant extract

27th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Eriobotrya Japonica Leaf Extract is an extract of the leaves of the Loquat, Eriobotrya japonica, Rosaceae

28 Palmitic Acid Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

28th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hexadecanoic acid

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

29th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, hydrogenated

Hydration
4 scientific references
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Nanocosmetics, June 2019, pages 95–140
  • Current Drug Delivery, 2016, pages 111–120
  • Pharmaceutical Research, February 2013, pages 538–55
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

30th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Glycine, N-(N-L-.gamma.-glutamyl-L-cysteinyl)-

Anti-Aging
8 scientific references
  • Journal of Cosmetic Dermatology, June 2019, pages 728–737
  • Clinical Cosmetic and Investigative Dermatology, April 2017, pages 147-153 and October 2014, pages 267-274
  • Nutrients, August 2017, pages 1-27
  • DermatoEndocrinology, July 2012, pages 308-319
  • Journal of Agricultural and Food Chemistry, 2011, pages 3, 940-3, 949
  • The Dermatologist, October 2011, volume 19, issue 10
  • Journal of Dermatologic Science, May 2010, pages 85-90
  • Free Radical Biology and Medicine, October 1994, pages 333-349
31 Phosphatidylcholine Surfactant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Surfactant

31st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins, egg yolk

Hydration
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

32nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio)

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

33rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Didodecyl 3,3'-thiodipropionate

Anti-Aging Dark Spot Fading
2 scientific references
  • Journal of the American Academy of Dermatology, February 2007, Supplement 2, ePublication
  • International Journal of Toxicology, May 2010, pages 137S–213S; and January/February 1992, pages 25–41
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

34th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 2,2-bis[[3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1-oxopropoxy] methyl]-1,3-propanediyl ester

35 Sodium Phytate Chelator
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Chelator

35th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Myo-Inositol, hexakis(dihydrogen phosphate), sodium salt

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

36th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Coptis Japonica Root Extract is an extract of the roots of Coptis japonica, Ranunculaceae

37 Allantoin Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Soothing

37th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urea, (2,5-dioxo-4-imidazolidinyl)-

Soothing
8 scientific references
  • Chemistry Series, March 2020, pages 7-21
  • Molecules, June 2019, pages 1-33
  • European Journal of Pharmacology, February 2018, pages 68-78
  • Journal of the American Academy of Dermatology, June 2017, Volume 76, Issue 2, Supplement 1
  • Pharmacognosy Review, Volume 5, July-December 2011
  • International Journal of Toxicology, May 2010, Supplement, pages 84S-97S
  • Journal of Occupational Medicine and Toxicology, October 2008, ePublication
  • https://wwwaccessdatafdagov/scripts/cdrh/cfdocs/cfcfr/CFRSearchcfm?CFRPart=347&showFR=1
38 Mentha Viridis Extract Plant extract
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

38th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Mentha Viridis Extract is an extract of the whole plant of the Garden Mint (spearmint), Mentha viridis L., Labiatae

39 Madecassoside Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

39th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

O-6-Deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oate

Anti-Aging Soothing
40 Lecithin Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant

40th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Lecithins. The complex combination of diglycerides of fatty acids linked to the choline ester of phosphoric acid

Hydration
5 scientific references
  • Cosmetics, November 2020, pages 1-19
  • International Journal of Toxicology, September 2020, pages 5S-25S
  • Molecules, March 2020, pages 1-9
  • Journal of the American Oil Chemists' Society, March 2014, pages 1, 093-1, 101
  • Scientia Pharmaceutica, July 2013, pages 1, 151-1, 166
41 Cellulose Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

41st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cellulose

42 Sodium Phosphate pH adjuster
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
pH adjuster

42nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sodium dihydrogenorthophosphate

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Humectant, Active

43rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Hyaluronic acid, sodium, salt

Hydration Anti-Aging Soothing
5 scientific references
  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line

44th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Polymer of glutamic acid

Hydration Anti-Aging
5 scientific references
  • Biomass Conversion and Biorefinery, March 2021, ePublication
  • Molecules, July 2020, pages 1–33
  • Journal of Materials Science, Materials in Medicine, Volume 31, May 2020, ePublication
  • Journal of Biomedical Materials Research, November 2017, pages
  • Saudi Journal of Biological Sciences, April 2014, pages 153–158
45 Dextrin Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

45th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Dextrin

Oil Control
8 scientific references
  • Oil-Absorbing Ingredients
  • Help for Oily Skin
  • Salicylic Acid for Skin
  • How BHA Exfoliants Work
  • Which BHA Exfoliant is Right for Me?
  • Niacinamide Benefits: What Does Niacinamide Do for Skin?
  • The Best Toners for Oily Skin
  • The Best Moisturizers for Oily, Acne-Prone Skin
46 Theobroma Cacao Extract Plant extract
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

46th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Theobroma Cacao Extract is the extract of Theobroma cacao., Sterculiaceae

47 Asiaticoside Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

47th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester (2alpha, 3beta, 4alpha)-

Anti-Aging Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

48th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Centella Asiatica Leaf Extract is an extract of the leaves of the Hydrocotyl, Centella asiatica L., Apiaceae

49 Cysteine Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

49th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

L-Cysteine

Hydration
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
50 Tocopherol Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

50th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; .alpha.-tocopherol; Vitamin E

Anti-Aging Evens Skin Tone Soothing
4 scientific references
  • Journal or Agricultural and Food Chemistry, June 2010, pages 7013-7020
  • Journal of Investigative Dermatology, November 2001, pages 1212-1217
  • Canadian Family Physician, July 2006, pages 855-856
  • Dermatologic Surgery, April 1999, pages 311-315
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

51st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

3-O-Ethyl Ascorbic Acid is the organic compound.

Anti-Aging Evens Skin Tone Dark Spot Fading
5 scientific references
  • Free Radical Biology and Medicine, September 2021, pages 151–169
  • Life, May 2021, pages 1–13
  • International Journal of Pharmaceutics, December 2019, pages 1–9
  • Journal of Cosmetic Science, July-August 2018, pages 233–243
  • AAPS PharmSciTech, June 2016, pages 767–777
52 Arbutin Antioxidant
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Antioxidant

52nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

4-Hydroxyphenyl-beta-D-glucopyranoside

Dark Spot Fading Evens Skin Tone
53 Bisabolol Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Soothing

53rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

(R*,R*)-.alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (theta,theta)-(+/-)-; 3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (S-(theta,theta))- (levomenol)

Soothing Anti-Aging
6 scientific references
  • CosmeticsInfoorg, Accessed May 2021, ePublication
  • International Journal of Cosmetic Science, August 2019, pages 299-303
  • International Journal of Toxicology, September 2017, pages 24S-25S
  • Cutis, November 2015, pages 337-342
  • Current Pharmaceutical Biotechnology, 2014, pages 173-181
  • Food and Chemical Toxicology, October 2011, pages 2580-2585
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Peptide

54th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Epidermal Growth Factor. It contains a maximum of 53 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids

55 Sh-oligopeptide-2 Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive, Active, Peptide

55th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

It is a single chain recombinant human peptide,produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Insulin-Like Growth Factor used as such or adapted to the production host.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Peptide

56th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

sh-Polypeptide-1 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Basic Fibroblast Growth Factor used as such or adapted to the production host. It contains a maximum of 288 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Peptide

57th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

It is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Fibroblast Growth factor 10 used as such or adapted to the production host. .

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Peptide

58th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

sh-Polypeptide-11 is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Acidic Fibroblast Growth Factor 1 used as such or adapted to the production host. It contains a maximum of 155 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Peptide

59th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

It is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Keratinocyte Growth Factor used as such or adapted to the production host.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Peptide

60th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

PDGF-2 PDGFB

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Peptide

61st on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

It is a single chain recombinant human peptide, produced by fermentation in E. Coli. The starting gene is a synthesized copy of the human gene which codes for Vascular Endothelial Growth Factor A used as such or adapted to the production host.

Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

62nd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Argania Spinosa Kernel Oil is the fixed oil expressed from the kernels, Argania Spinosa (L.), Sapotaceae

Hydration Anti-Aging
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
63 Cholesterol Emollient
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient, Surfactant, Texture agent

63rd on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Cholest-5-en-3-ol (beta)-

Hydration Anti-Aging
4 scientific references
  • Frontiers in Bioengineering and Biotechnology, August 2015, pages 1-6
  • Journal of Cosmetic Dermatology, July 2007, pages 239-242
  • Journal of Structural Biology, June 2007, pages 386-400
  • International Journal of Toxicology, 2006, pages 1-89
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Emollient

64th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Sesamum Indicum Seed Oil is the oil obtained from the seed of the Sesame, Sesamum indicum L., Pedaliaceae

65 Chitosan Occlusive
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Occlusive

65th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Chitin, deacylated

Soothing
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Plant extract

66th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Serenoa Serrulata Fruit Extract is an extract of the fruit of the Saw Palm, Serenoa Serrulata, Palmaceae

67 Ascorbic Acid Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Antioxidant, pH adjuster

67th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ascorbic acid

Anti-Aging Dark Spot Fading Evens Skin Tone
12 scientific references
  • Drug Delivery, February 2021, pages 445-453
  • Journal of Cosmetic Dermatology, December 2020, pages 3, 262-3, 269
  • Journal of Oral and Maxillofacial Pathology, May-August 2020, pages 374-382
  • Journal of Cosmetic Dermatology, March 2020, pages 671-676
  • Journal of Clinical and Aesthetic Dermatology, July 2017 pages 14-17
  • Journal of Drugs in Dermatology, July 2016, pages 863-867
  • Clinical, Cosmetic, and Investigational Dermatology, September 2015, pages 463-470
  • Indian Dermatology Online Journal, April-June 2013, pages 143-146
  • AAPS PharmSciTech, July 2011, pages 917-923
  • Journal of Drugs in Dermatology, July 2008, Supplement, pages s2-s6
  • International Journal of Toxicology, Supplement 2, March 2005, pages 51-111
  • Skin Pharmacology and Physiology, July-August 2004, pages 200-206
68 Beta-sitosterol Texture agent
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Texture agent

68th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Stigmast-5-en-3-.beta.-ol

Hydration
8 scientific references
  • Supercharged Hydration
  • How Hyaluronic Acid Benefits Skin
  • What is Dehydrated Skin & How to Choose the Best Products
  • What Your Moisturizer Must Contain
  • Moisturizer Myths You Should Stop Believing Now
  • The Benefits of Glycerin in Skin Care
  • The Best Face Oils for Skin
  • How Facial Oils Help Skin
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active, Antioxidant

69th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

2-O-alpha-D-Glucopyranosyl-L-ascorbic acid

Anti-Aging Dark Spot Fading Evens Skin Tone
11 scientific references
  • Journal of the American Academy of Dermatology, December 2020 Supplement, page AB192
  • Nanomaterials, August 2020, pages 1-13
  • Journal of Oral and Maxillofacial Pathology, May-August 2020, pages 374-382
  • Genes, February 2020, ePublication
  • Cosmetics, October 2019, ePublication
  • International Journal of Cosmetic Science, August 2019, pages 378-386
  • International Journal of Pharmaceutics, May 2019, pages 21-29
  • Asian Journal of Beauty and Cosmetology, December 2018, pages 599-607
  • Nutrients, August 2017, pages 1-27
  • Journal of Cutaneous and Aesthetic Surgery, January-March 2013, pages 4-11
  • Skin Research and Technology, May 2006, pages 105-113
70 Ceramide NP Active
Estimated level
under 1%
Confidence
Moderate — listed below the 1% line
Roles
Active

70th on the list, below the 1% line — present at under 1%, which for most ingredients is the level they work at.

Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Hydration Anti-Aging
11 scientific references
  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1, 466-1, 476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1, 126-1, 136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271

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Frequently asked questions

What ingredients are in No.5+ Glutathione Vitamin Dark Spot Cream?

WATER, DIPROPYLENE GLYCOL, GLYCERIN, NIACINAMIDE, OCTYLDODECANOL, HELIANTHUS ANNUUS SEED OIL, BUTYLENE GLYCOL, TREHALOSE, PENTYLENE GLYCOL, 1,2-HEXANEDIOL, CAPRYLYL METHICONE, PANTHENOL, POLYMETHYLSILSESQUIOXANE, PROPANEDIOL, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, CETEARYL OLIVATE, POLYGLYCERYL-10 BEHENATE/EICOSADIOATE, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, SORBITAN OLIVATE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, TROMETHAMINE, XANTHAN GUM, C12-16 ALCOHOLS, ETHYLHEXYLGLYCERIN, SORBITAN ISOSTEARATE, ADENOSINE, ERIOBOTRYA JAPONICA LEAF EXTRACT, PALMITIC ACID, HYDROGENATED LECITHIN, GLUTATHIONE, PHOSPHATIDYLCHOLINE, POLYGLYCERYL-10 LAURATE, DILAURYL THIODIPROPIONATE, PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE, SODIUM PHYTATE, COPTIS JAPONICA ROOT EXTRACT, ALLANTOIN, MENTHA VIRIDIS EXTRACT, MADECASSOSIDE, LECITHIN, CELLULOSE, SODIUM PHOSPHATE, SODIUM HYALURONATE, POLYGLUTAMIC ACID, DEXTRIN, THEOBROMA CACAO EXTRACT, ASIATICOSIDE, CENTELLA ASIATICA LEAF EXTRACT, CYSTEINE, TOCOPHEROL, 3-O-ETHYL ASCORBIC ACID, ARBUTIN, BISABOLOL, SH-OLIGOPEPTIDE-1, SH-OLIGOPEPTIDE-2, SH-POLYPEPTIDE-1, SH-POLYPEPTIDE-10, SH-POLYPEPTIDE-11, SH-POLYPEPTIDE-3, SH-POLYPEPTIDE-59, SH-POLYPEPTIDE-9, ARGANIA SPINOSA KERNEL OIL, CHOLESTEROL, SESAMUM INDICUM SEED OIL, CHITOSAN, SERENOA SERRULATA FRUIT EXTRACT, ASCORBIC ACID, BETA-SITOSTEROL, ASCORBYL GLUCOSIDE, CERAMIDE NP.

What are the active ingredients in No.5+ Glutathione Vitamin Dark Spot Cream?

NIACINAMIDE, PANTHENOL, SODIUM HYALURONATE, 3-O-ETHYL ASCORBIC ACID, SH-OLIGOPEPTIDE-1, SH-OLIGOPEPTIDE-2, SH-POLYPEPTIDE-1, SH-POLYPEPTIDE-10, SH-POLYPEPTIDE-11, SH-POLYPEPTIDE-3, SH-POLYPEPTIDE-59, SH-POLYPEPTIDE-9, ASCORBIC ACID, ASCORBYL GLUCOSIDE, CERAMIDE NP.

How do I use No.5+ Glutathione Vitamin Dark Spot Cream?

Apply it after serums. Seal in your serums with it; in the morning, sunscreen still goes on top.

What skin types is No.5+ Glutathione Vitamin Dark Spot Cream good for?

Judged on how rich the formula reads from its ingredient list, it suits Balanced skin best. It is the least natural fit for Dry, Combination (dry) skin.

Is No.5+ Glutathione Vitamin Dark Spot Cream good for sensitive skin?

No ingredient in this formula carries a common-irritant flag, making it a reasonable option for reactive skin. A patch test is still recommended, as individual skin reactivity varies.

Is No.5+ Glutathione Vitamin Dark Spot Cream fungal acne safe?

8 ingredients could feed malassezia: Helianthus Annuus Seed Oil, Cetearyl Olivate, Polyglyceryl-10 Behenate/eicosadioate, Sorbitan Olivate, Sorbitan Isostearate, Polyglyceryl-10 Laurate, Argania Spinosa Kernel Oil, Sesamum Indicum Seed Oil. That describes the yeast's food supply, not a prediction that they will cause a breakout.

Can I use No.5+ Glutathione Vitamin Dark Spot Cream while pregnant?

It contains Arbutin, which are usually reviewed with a doctor during pregnancy. Ask your doctor or midwife before using it.

Is No.5+ Glutathione Vitamin Dark Spot Cream fragrance free?

Yes. Reading the full ingredient list, this formula is fragrance-free.

Does No.5+ Glutathione Vitamin Dark Spot Cream contain alcohol?

No. Reading the full ingredient list, this formula is no drying alcohol.

Is No.5+ Glutathione Vitamin Dark Spot Cream silicone free?

No — it contains Caprylyl Methicone, Polymethylsilsesquioxane.

Does No.5+ Glutathione Vitamin Dark Spot Cream contain essential oils?

Yes — it contains Mentha Viridis Extract.

Is No.5+ Glutathione Vitamin Dark Spot Cream paraben free?

Yes. Reading the full ingredient list, this formula is paraben-free.

What can I layer with No.5+ Glutathione Vitamin Dark Spot Cream?

It layers well with Vitamin C (L-ascorbic acid), PHAs (gluconolactone), Azelaic acid, Copper peptides, Bakuchiol, Niacinamide. Take more care combining it with Benzoyl peroxide, Retinoids (retinol, retinal), AHAs (glycolic, lactic), BHA (salicylic acid) — use them in separate routines or on alternate days.

When should I apply No.5+ Glutathione Vitamin Dark Spot Cream?

Use it morning and evening, after serums.

How many ingredients does No.5+ Glutathione Vitamin Dark Spot Cream have?

It lists 70 ingredients, of which 15 are recorded as actives.

Who makes No.5+ Glutathione Vitamin Dark Spot Cream?

Numbuzin, a brand based in Korean.

Brand
Numbuzin
Country
Korean

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